BIOE - BIOENGINEERING

BIOE - 1000   ORIENTATION AND INTRODUCTION TO BIOENGINEERING
[2 hours]  Basic orientation to The University of Toledo policies and procedures for Bioengineers, other engineering disciplines and the co-op program. Remainder of course is focused on a general introduction to Bioengineering including examples of engineering analysis and design applied to each of the following subjects: Bioelectrical Engineering, Biomechanical Engineering, and Cellular Engineering.  A review of technological needs, design issues, testing procedures, statistical analysis, governmental regulation, evaluation of costs and benefits, quality of life, and ethical issues.  Prerequisite: Acceptance into Bioengineering

BIOE - 1200   COMPUTER PROGRAMMING FOR BIOENGINEERING
[3 hours]  Introduction and application of computer programming and software such as C++, MathCad, MatLab, and Excel.  Includes concept and properties of an algorithm, analysis of computational problems, flow diagrams, and applications to numerical problem solving methods.  Prerequisite: Acceptance into Bioengineering

BIOE - 2100   BIOENGINEERING THERMODYNAMICS
[3 hours]  Principles of thermodynamics and conservation of mass applied to living systems, biomedical devices, and bioprocesses.  Prerequisite: PHYS 2130; MATH 1860

BIOE - 2200   BIOMATERIALS
[3 hours]  Chemical, mechanical and immunological properties of biomaterials and strategies for their effective use in the fields of medicine and dentistry as well as in cell culturing and processing operations.  Prerequisite: PHYS 2140; MATH 2850; CHEM 1240; BIOL 2150; BIOE 2100

BIOE - 3110   BIOMECHANICS OF THE HUMAN BODY I
[3 hours]  Application of mechanics to understand the behavior of tissues and organs at gross and microscopic levels. Techniques in tissue engineering. Prerequisite: PHYS 2140; MATH 3860; BIOL 2170; BIOE 2200

BIOE - 3120   BIOMECHANICS OF THE HUMAN BODY II
[3 hours]  Bioviscoelastic fluids and solids.  Non-newtonian behavior of blood, synovial fluid, mucus, and protoplasm.  Basic mechanical properties of collagen and elastin, bone, cartilage, muscles, blood vessels, and other living tissues.  Application of continuum mechanics.  Artificial implantable materials and design of prosthetic devices.  Prerequisite: BIOE 3110

BIOE - 3200   PHYSIOLOGY FOR BIOENGINEERS
[3 hours]  Review of general physiological principles followed by a comprehensive study of the human circulatory, respiratory, digestive and excretory systems.  An emphasis will be placed on homeostatic mechanisms.  Prerequisite: BIOL 2170

BIOE - 3300   BIOMEDICAL ELECTRONICS
[3 hours]  Measurement circuits, signal analysis, and computer design in biological systems and medicine.  Prerequisite: EECS 3200

BIOE - 3400   BIOTRANSPORT PHENOMENA
[3 hours]  The quantitative description of momentum transport (viscous flow) and mass transport (convection and diffusion) in living systems.  Application of engineering methods to model and quantify aspects of bioengineering systems.  Prerequisite: MATH 3860; BIOE 3200

BIOE - 3940   CO-OP EXPERIENCE
[1 hour]  Approved co-op experience.  Course may be repeated.  Prerequisite: BIOE 1200

BIOE - 4100   BIOINSTRUMENTATIONS AND MEASUREMENT LAB
[3 hours]  Introduction to measurement theory and techniques for biomedical instrumentation.  Prerequisite: BIOE 3300 Corequisite: BIOE 3200

BIOE - 4200   BIOSYSTEMS AND CONTROL
[3 hours]  Systems and control theory applied to bioengineering.  Prerequisite: BIOE 3300; MATH 3860

BIOE - 4300   ANALYSIS OF BIOENGINEERING SYSTEMS
[3 hours]  Application of modern computing methods to the numerical and statistical analysis of bioengineering systems.  Prerequisite: BIOL 2170; BIOE 3300; MATH 3860

BIOE - 4400   BIOENGINEERING DESIGN PROJECT
[4 hours]  This course integrates the engineering and life science backgrounds of senior bioengineering students through the presentation of design principles for medical devices, biological processes, and biological systems.  Prerequisite: Senior Standing; BIOE 4100, BIOE 4200, BIOE 4300; MIME 2600

BIOE - 4500   BIOENGINEERING LABORATORY
[3 hours]  A laboratory course providing the undergraduate student the opportunity to explore and experience fundamental concepts and to use laboratory research tools and equipment.  Prerequisite: Senior Standing. 1 hour lecture and 3 hour laboratory.

BIOE - 4610   ARTIFICIAL ORGANS
[3 hours]  The application of engineering principles to the design and analysis of artificial organs and their clinical application.  Prerequisite: Senior Standing

BIOE - 4620   BIOCHEMICAL ENGINEERING
[3 hours]  The application of engineering principles to the design and analysis of biological processes that employ living organisms or biochemicals.  Prerequisite: Senior Standing

BIOE - 4630   BIOSEPARATIONS
[3 hours]  Practical and theoretical aspects of processes required to separate and purify cells, proteins, and other biological compounds.  Prerequisite: Senior Standing

BIOE - 4640   MEDICAL IMAGING
[3 hours]  An introduction to the physical principles, design and function of medical diagnostic imaging systems.  Prerequisite: Senior Standing; BIOE 3300

BIOE - 4650   INTELLIGENT MEDICAL DECISION MAKING
[3 hours]  Introduction to expert systems and their characteristics, knowledge representation, inference techniques, dealing with uncertain information in knowledge-based systems, and machine learning techniques for rule extraction.  Prerequisite: Senior standing

BIOE - 4910   BIOENGINEERING HONORS THESIS
[1 - 3 hours]  Thesis research.  The student completes and defends a written thesis under the direction and guidance of their faculty research adviser.  Prerequisite: Senior standing in Bioengineering

BIOE - 4980   BIOENGINEERING SPECIAL TOPICS
[1 - 3 hours]  Selected subjects in the field of bioengineering with intensive investigation of the recent literature in a few areas of special interest to the class and the professor.  Prerequisite: Consent of instructor

BIOE - 4990   BIOENGINEERING INDEPENDENT STUDY
[1 - 3 hours]  The student, under the guidance of their research adviser, explores in-depth specific areas or topics related to their research.  Prerequisite: Consent of instructor

BIOE - 5110   BIOENGINEERING PRINCIPLES
[3 hours]  This course provides new bioengineering graduate students with the knowledge base needed to apply engineering concepts to the field of bioengineering. This course will also provide the necessary background needed for additional study in the life sciences and bioengineering.

BIOE - 5120/7120   BIOENGINEERING LABORATORY
[1 hour]  A laboratory course providing the bioengineering graduate student the opportunity to explore and experience fundamental concepts and to use laboratory research tools and equipment.  Prerequisite: Graduate standing.  Corequisite: BIOE 5110

BIOE - 5200 PHYSIOLOGY AND ANATOMY FOR BIOENGINEERS
[3 hours]  Review and study of general physiological principles and bioengineering perspectives of the human circulatory, respiratory, digestive, immune, nervous, muscular, and excretory systems.

BIOE - 5260/7260   MEDICAL IMAGING SYSTEMS I
[3 hours]  An introduction to the physical principles, design and function of x-ray based diagnostic imaging systems, including radiographic, fluoroscopic, and computer tomography (CT) systems.  Prerequisite: EECS 3200 or consent of instructor.

BIOE - 5720/7720   INTRODUCTION TO BIOMATERIALS
[3 hours]  This course will address chemical, mechanical and immunological properties of biomaterials and strategies for their effective use in the fields of medicine and dentistry as well as in cell culturing and processing operations.  Biomaterials applications in artificial organs, bone/joint replacement, plastic surgery, immunoisolation, and controlled drug delivery will be addressed.  The continued development and fabrication of biocompatible materials is critical for these areas.  Prerequisite: Consent of instructor.

BIOE - 5930/7930   BIOENGINEERING SEMINAR
[1 hour]  Presentations of ongoing research in the field of bioengineering.  Includes presentations by guest speakers, faculty, and graduate students.  Prerequisite: Graduate Standing.

BIOE - 5950/7950 BIOENGINEERING SEMINAR
[1 hour] Presentation of ongoing research in the field of bioengineering.  Includes presentations by guest speakers, faculty, and graduate students.  Prerequisite: Must have taken and successfully completed 2 semester hours of BIOE 5930/7930.

BIOE - 5980/7980   SPECIAL TOPICS IN BIOENGINEERING
[1 - 5 hours]  Selected subjects in the field of bioengineering with intensive investigation of the recent literature in a few areas of special interest to the class and the professor.      Prerequisite: Consent of instructor.

BIOE - 5990/7990   INDEPENDENT STUDY IN BIOENGINEERING
[1 - 6 hours]  The student, under the guidance of their research adviser, explores in-depth specific areas or topics related to their thesis or dissertation research.  Prerequisite: Graduate standing, consent of faculty adviser.  Corequisite: BIOE 5110

BIOE - 6210/8210   OPTICAL INSTRUMENTATION FOR BIOENGINEERING
[3 hours]  Introduction to the theory and design of topical instruments for bioengineers.  Instruments using geometrical, physical and quantum optical principles will be discussed.  Prerequisite: Graduate standing.

BIOE - 6220/8220  SEMICONDUCTOR BIOSENSORS
[3 hours]  Introduction to the theory and design of semiconductor sensors for measuring biological parameters.  All major aspects of fabrication and characterization will be discussed.  Prerequisite: Graduate standing.

BIOE - 6230/8230   BIOELECTRICAL INSTRUMENTATION
[3 hours]  This course is intended to give students in bioengineering a basic understanding of bioelectrical instrumentation and physiological measurements.  Prerequisite: Graduate standing.

BIOE - 6240/8240   BIOELECTRICAL INSTRUMENTATION LABORATORY
[1 hour]  Laboratory introduction to measurement of bioelectrical potentials and use of instruments.      Prerequisite: Graduate standing.

BIOE - 6250/8250   ADVANCED BIOELECTRICAL INSTRUMENTATION
[3 hours]  Advanced discussion of the theory and design of bioelectrical instrumentation.  Computer analysis of data, data conversion and complex sensor systems will be considered.  Prerequisite: Graduate standing.

BIOE � 6270/8270   MEDICAL IMAGING SYSTEMS II
[3 hours]  An introduction to the physical principles, design and function of ultrasonic, nuclear medicine, and magnetic resonance imaging (MRI) diagnostic imaging systems.  Prerequisite: EECS 3200 or consent of instructor.

BIOE - 6280/8280   ADVANCED IMAGING TECHNIQUES
[3 hours]  Contemporary techniques for producing and processing images and image data, including remote sensing, industrial inspection and medical diagnosis.  Modeling and analysis of spatially invariant image sequences.  Image reconstruction from projections.  Prerequisite: Prior imaging course.

BIOE - 6290/8290   BIOSIGNAL PROCESSING
[3 hours]  Analog and discrete-data bioelectrical and bioengineering signals and their characteristics, bioengineering signal classification, signal processing and analysis techniques and decision making.  Prerequisite: Signal & System Analysis

BIOE - 6310/8310   BIOCHEMICAL ENGINEERING PRINCIPLES
[3 hours]  The application of engineering principles to the design and analysis of biological processes that employ living organisms or biochemicals.

BIOE - 6340/8340   BIOSEPARATIONS
[3 hours]  Practical and theoretical aspects of various processes required to separate and purify cells, proteins, and other biological compounds.  Topics covered include various types of chromatography, liquid/liquid separations, solid/liquid separations, membrane processing, flow cytometry, and field-enhanced separations.  This course will focus on new and non-traditional methods.  Prerequisite: BIOE 6310 or consent of instructor.

BIOE - 6410/8410   BIOLOGICAL AND ARTIFICIAL NEURAL NETWORKS
[3 hours]  Introduction to biological neural networks and cognitive science. Discriminant functions,  training methods, TLUs, perceptrons and adalines. Backpropagation, and statistical methods.  Kohonen networks.  Hopfield network.  Associative memories, Radial Basis Functions. Ontogenic neural networks. Neuro-fuzzy networks.  Prerequisite: MATH- Linear Algebra;  MATH-Prob.Theory; Data Structures.

BIOE - 6420/8420   MEDICAL DATA MINING
[3 hours]  Fuzzy sets, the extension principle, fuzzy relations, fuzzy logic.  Approximate operations on sets, lower and upper approximation, dependency and reduction of attributes.  Populations of objects, fitness function, mutation, crossover.  Prerequisite: MATH Linear Algebra; MATH Prob. Theory;  Data Structures.

BIOE - 6430/8430   INTELLIGENT MEDICAL DIAGNOSTIC SYSTEMS
[3 hours]  Knowledge representation, dealing with uncertainty in knowledge-based systems.  Machine learning techniques for rule extraction.  Prerequisite: BIOE 5420

BIOE - 6440/8440  WAVELETS & THEIR APPLICATIONS
[3 hours]  Fundamentals of series expansion using wavelets, continuous wavelets and frames, and signal compression.  Applications of wavelets in signal processing, signal reconstruction, compression and analysis for biomedical applications.  Background in signal processing is desired.

BIOE - 6510/8510   OCCUPATIONAL BIOMECHANICS
[3 hours]  Occupational biomechanics deals with the mechanical behavior of musculoskeletal tissues during performance of physical work.  It combines knowledge of mechanics and physiology together with industrial work specifications and practice and provides an understanding of the physics of manual industrial activities.  Prerequisite: Undergraduate mechanics & statics courses.

BIOE - 6520/8520   ORTHOPAEDIC BIOMECHANICS
[3 hours]  The course of orthopaedic biomechanics has been designed to fuse the biological and physiological problems with the science and technology of engineering.  It focuses on a brief review of the physiology and biology of the human body, introduces the physical law of mechanics, brings some engineering knowledge and reviews some orthopaedic applications in modern surgery.

BIOE - 6700/8700   ARTIFICIAL ORGANS
[3 hours]  This course is concerned with the application of engineering principles to the design and analysis of artificial organs and their clinical application.

BIOE - 6710/8710   TISSUE ENGINEERING
[3 hours]  Tissue engineering combines engineering, materials science, and cellular biology knowledge to solve the critical problems of tissue loss and organ failure.  This course aims to not only teach aspects of engineering and cellular biology in the same course, but also to present them in such a way that the student learns the cellular phenomena involved in tissue development and growth and gains an appreciation of the role of biochemical and mechanical environment in regenerating tissues.

BIOE - 6730/8730   BIOLOGICAL TRANSPORT PHENOMENA
[3 hours]  Application of transport phenomena and reaction engineering in the understanding of signaling, growth processes, and the flow of biological fluids in mammalian vessels in living systems.  Prerequisite: consent of instructor.

BIOE - 6810   SOLID STATE ELECTRONICS WITH BIOENGINEERING APPLICATIONS
[3 hours]  Course is crosslisted as EECS 6810. A comprehensive treatment of the theory and operation of physical electronic devices emphasizing electrical transport in metals and semiconductors, various models of BJT�s and FET�s, and applications to biochemical and biomechanical sensing will be considered. Prerequisite: Graduate standing

BIOE - 6820   MICROELECTRONIC AND MICROMECHANICAL FABRICATION
[3 hours]  Course is crosslisted as EECS 6820. A comprehensive treatment of the theory, principles and techniques associated with microfabrication of electronic circuits and biosensors. Prerequisite: Graduate standing

BIOE - 6830  COMPUTATIONAL METHODS OF NEURAL FUNCTIONS
[3 hours]  The course focuses on the development and analysis of mathematical models of biological processes. Students will use advanced mathematics and computers to implement models from the literature.  Prerequisite: Graduate standing

BIOE - 6920   BIOENGINEERING PROJECT
[1 - 4 hours]  The student performs a special project of an advanced nature in bioengineering.  A written report is required.  Prerequisite: Graduate standing; consent of instructor.

BIOE - 6960   BIOENGINEERING RESEARCH AND THESIS - MASTER�S
[1 - 6 hours]  Graduate thesis research.  The student completes and defends a written thesis under the direction and guidance of their faculty research adviser.  Prerequisite: Consent of instructor.

BIOE - 8960   BIOENGINEERING DISSERTATION
[1 - 16 hours]  Original investigations of significant bioengineering problems at the graduate level under the guidance of a member of the faculty.  Prerequisite: Consent of department

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Last Updated: 5/5/14