PHCL - 2600 FUNCTIONAL ANATOMY AND PATHOPHYSIOLOGY I
[4 hours] A study of functional anatomy, physiology and pathophysiology
to serve as background for the understanding of the action of drugs. Prerequisite: CHEM 1230, 1240, 1280, 1290; BIOL 2150, 2160, 2170
and 2180 Corequisite: 2nd year standing
PHCL - 2620 FUNCTIONAL ANATOMY AND PATHOPHYSIOLOGY II
[4 hours] A continuation of PHCL 2600. Prerequisite: PHCL 2600
PHCL - 3700 PHARMACOLOGY I: PRINCIPLES OF PHARMACOLOGY, AUTONOMIC PHARMACOLOGY AND NON-STEROIDAL ANTI-INFLAMMATORY AGENTS AND
RELATED PHARMACOLOGY
[3 hours] An introduction to the principles of pharmacology and the pharmacology of the autonomic nervous system.
Non-steroidal anti inflammatory agents are also discussed. Prerequisite: Admission to professional division Corequisite: MBC 3550,
MBC 3310
PHCL - 3720 PHARMACOLOGY II: ENDOCRINE AND CNS PHARMACOLOGY
[3 hours] The pharmacology of drugs acting upon the endocrine
and reproductive systems will be discussed, followed by a treatment of drugs used in the management of sleep disorders, for anxiety, for
affective illness, for schizophrenia, and for seizure disorders. Prerequisite: PHCL 3700 Corequisite: MBC 3560
PHCL - 4140 INTERPRETATION OF PHARMACEUTICAL DATA
[3 hours] A course designed to emphasize the interpretation of statistical
data as it appears in the literature which is related to pharmacy. The concepts of statistics will be discussed. Experimental design
as well as appropriateness of analytical methodology and conclusions will be stressed. Prerequisite: Admission to the professional
division, or upper division, or consent of instructor.
PHCL - 4150 BIOPHARMACEUTICS AND PHARMACOKINETICS
[4 hours] Application of kinetic models to the processes of drug
absorption, distribution, biotransformation, and excretion. The influence of dosage form and physiology on these processes.
Application of pharmacokinetic principles to clinical situations. Prerequisite: PHPR 3080, Consent of Instructor
PHCL - 4300 SELECTED TOPICS IN PHARMACOLOGY
[2 hours] The pharmacology of selected classes of agents will be discussed.
Discussions will include the pharmacology of: Drugs used to treat asthma, antihistamines, drugs used to treat migraine, drugs to manage movement
disorders, local anesthetics, and antineoplastic agents. Prerequisite: Completion of PHCL 4700
PHCL - 4600 EPIDEMIOLOGY
[4 hours] This course is intended to provide fundamental concepts of epidemiology and its
basic research methods. The course is designed as a prerequisite for pharmacoepidemiology. Prerequisite: 4th year standing or
permission of instructor
PHCL - 4620 PHARMACOEPIDEMIOLOGY
[4 hours] This course is intended to give an overview of and terminology commonly used in
pharmacoepidemiology and to teach students how to review and comprehend pharmacoepidemiologic studies. Prerequisite: PHCL 4610, or permission of
instructor. Corequisite: PHCL 5140
PHCL - 4700 PHARMACOLOGY III: CNS AND CARDIOVASCULAR PHARMACOLOGY
[3 hours] The pharmacology of central nervous system active
agents such as opioid analgesics and alcohol. Continues from PHCL 3720. Agents acting on the cardiovascular and renal systems are discussed.
Prerequisite: PHCL 3720
PHCL - 4720 PHARMACOLOGY IV: CHEMOTHERAPEUTIC AGENTS
[3 hours] The pharmacology of anti-infective chemotherapeutic agents is
presented. Issues such as the mechanism of antimicrobial action, disposition, resistance, and problems attending the use of antimicrobial
drugs will be discussed. Prerequisite: PHCL 4700, 4150, MBC 3600
PHCL - 4730 TOXICOLOGY I
[3 hours] A synopsis of the basic elements of toxicology including dose-response, lethal dose-50, margin
of safety, mechanisms of toxicity, and nature of toxic injuries including mutagenesis and carcinogenesis. Treatments for poisonings will
not be treated in detail (see PHCL 4740) Prerequisite: 4th yr standing in the College; PHCL 4700 for B.S. Pharm, MBC 4300 for B.S. Pharm;
permission of instructor for non-Pharmacy majors. Co-requisite: PHCL 3700.
PHCL - 4740 INTRODUCTION TO CLINICAL TOXICOLOGY
[2 hours] An introduction to the diagnosis and treatment of human poisoning
and risk assessment will be discussed utilizing the lecture and case presentation format. Prerequisite: 4th or 5th yr. standing in the
College; PHCL 4700
PHCL - 4750 TOXICOLOGY II
[3 hours] This course provides the students with an overview of environmental toxicology, which
emphasizes both air and water pollution. It also reviews the applications of different areas of toxicology, such as food toxicology emphasizing
the safety standards of food and methods of evaluation of food safety, analytic toxicology and its applications in forensic toxicology, and
occupational toxicology, emphasizing the health effects of industrial chemicals on workers and also the permissible levels of these chemicals in
the work place. Prerequisite: Completion of PHCL 4730 or permission of instructor.
PHCL - 4760 TOXICOKINETICS
[3 hours] The theory and practice of using kinetic principles to model the time course of toxic
chemicals in the body and in the environment. Relation of the chemical time course to negative outcomes and application to risk assessment.
Hands-on practice with kinetic analysis methods and software. Prerequisite: 4th year standing; permission for non-pharmacy students
PHCL - 4770 TOXICOLOGICAL RISK ASSESSMENT
[3 hours] Study of human health risk assessment based on National Research Council
paradigm. Topics (pharmacokinetic/dynamic modeling, etc.) are designed to provide the student with the tools necessary to conduct
quantitative risk assessment. Prerequisite: PHCL 4760 or PHCL 4150 or consent of instructor
PHCL - 4780 PRACTICUM IN TOXICOLOGY
[3 hours] In this experiential course students will acquire practical knowledge and
hands-on experience in the areas of pharmacology and/or toxicology by working at private or government laboratories. Prerequisite:
fourth year student in good standing in BSPS program. All required courses in the first 3 years of the PTOX major must have been successfully
completed.
PHCL - 4800 HUMAN-XENOBIOTIC INTERACTIONS
[3 hours] This course will summarize the ways in which xenobiotics affect the
human condition both in the context of therapeutic benefit and also chemically-induced diseases. Existing strategies for developing xenobiotics
to control disease and for managing xenobiotics in order to limit disease will be discussed. Prerequisite: PHCL 3700, 3720, 4700,
4730, 4140
PHCL - 4850 DRUG DISPOSITION
[2 hours] The influence of host factors such as disease states, drug-drug interactions, and
environmental chemical exposure will be discussed within the framework of basic principles of drug absorption, distribution, metabolism, and
excretion. Prerequisite: PHCL 4150
PHCL - 4900 HONORS SEMINAR IN PHARMACOLOGY
[1-3 hours] An examination of a specific question in the context of the primary
literature in pharmacology and in the context of the student�s own findings based on his/her thesis research. Prerequisite: 4th yr.
standing; 3.3 overall GPA; 3.5 GPA in Pharmacology/or instructor consent
PHCL - 4910 PROBLEMS IN PHARMACOLOGY
[1 - 3 hours] An examination of a specific question in pharmacology which can be
answered through application of experimental work. Prerequisite: Consent of Instructor
PHCL - 4960 HONORS THESIS IN PHARMACOLOGY
[2-5 hours] An examination of a specific question in pharmacology which can be
answered through application of experimental work. Prerequisite: 4th. yr. standing; 3.3 GPA overall; 3.5 GPA in Pharmacology/or
consent of instructor
PHCL - 5140 INTERPRETATION OF PHARMACEUTICAL DATA
[2 hours] A course designed to emphasize the presentation, analysis and
interpretation of data in the pharmaceutical sciences. The concepts of statistics will be discussed. Experimental design as well as
appropriateness of analytical methodology and conclusions will be stressed. Prerequisite: Admission to the graduate program or consent of
instructor.
PHCL - 5300 SELECTED TOPICS IN PHARMACOLOGY
[2 hours] This course discusses the pharmacodynamics and pharmacotherapeutics of
selected classes of pharmacologic agents. The pathophysiology of the disease states for which these agents are commonly employed will be
described. Prerequisite: PHCL 5700
PHCL - 5600 RESEARCH METHODS IN EPIDEMIOLOGY
[4 hours] This course is intended to provide fundamental concepts of
epidemiology and its basic research methods. The course is designed as a prerequisite for pharmacoepidemiology. Prerequisite: 4th
year standing or permission of instructor
PHCL - 5620 PHARMACOEPIDEMIOLOGY
[4 hours] This course is intended to give an overview of and terminology commonly used in
pharmacoepidemiology and to teach students how to review and comprehend pharmacoepidemiologic studies. Prerequisite: PHCL 4610, or permission of
instructor. Corequisite: PHCL 5140
PHCL - 5700 PHARMACOLOGY I �PRINCIPLES OF PHARMACOLOGY, AUTONOMIC PHARMACOLOGY AND NON-STEROIDAL ANTI-INFLAMMATORY AGENTS AND
RELATED PHARMACOLOGY
[3 hours] An introduction to the principles of pharmacology and the pharmacology of the autonomic system.
Non-steroidal anti inflammatory agents are also discussed. Prerequisite: Admission to the Graduate Program
PHCL - 5720 PHARMACOLOGY II: ENDOCRINE AND CNS PHARMACOLOGY
[3 hours] The pharmacology of drugs acting upon the
endocrine and reproductive systems will be discussed, followed by a treatment of drugs used in the management of sleep disorders, for anxiety,
for affective illness, for schizophrenia, and for seizure disorders. Prerequisite: PHCL 5700
PHCL - 5730 TOXICOLOGY I
[3 hours] This course reviews the basic elements of toxicology. It includes those principles most
frequently involved in a full understanding of toxicologic events, such as dose-response, lethal dose-50 (LD50) and margin of safety. It also
identifies toxic chemicals and their systemic sites and mechanisms of action. Finally, this course provides information about the kinds of toxic
injuries produced in specific organs or systems and the toxic agents that produce these effects. Information about the possible management of
some cases of intoxication or poisoning by some agents will be briefly reviewed. Prerequisite: PHCL 5700
PHCL - 5750 TOXICOLOGY II
[3 hours] This course provides the students with an overview of environmental toxicology, which
emphasizes both air and water pollution. It also reviews the applications of different areas of toxicology, such as food toxicology emphasizing
the safety standards of food and methods of evaluation of food safety, analytic toxicology and its applications in forensic toxicology, and
occupational toxicology, emphasizing the health effects of industrial chemicals on workers and also the permissible levels of these chemicals in
the work place. Prerequisite: Completion of PHCL 5730 or permission of instructor.
PHCL - 5760 TOXICOKINETICS
[3 hours] The theory and practice of using kinetic principles to model the time course of toxic
chemicals in the body and in the environment. Relation of the chemical time course to negative outcomes and application to risk assessment.
Hands-on practice with kinetic analysis methods and software. Prerequisite: Graduate status
PHCL - 5900 DRUG DISPOSITION
[2 hours] The influence of host factors such as disease states, drug-drug interactions, and
environmental chemical exposure will be discussed within the framework of basic principles of drug absorption, distribution, metabolism, and
excretion. Prerequisite: Graduate status
PHCL - 5990 PROBLEMS IN PHARMACOLOGY
[1 - 6 hours] Tutorial or directed individual research in pharmacology.
Prerequisite: Graduate status
PHCL - 6150 ADVANCED PHARMACOKINETICS
[2 hours] A study of the mathematical models describing the time course of drugs in
the body and their application in the interpretation of in vivo data. Prerequisite: Admission to the graduate program; or consent of
instructor
PHCL - 6600 SEMINAR IN PHARMACOLOGY
[1 hour] Pharmacology students will attend seminar presentations offered through the
seminar/colloquia programs in the departments of Biology and Chemistry and in the College of Pharmacy, and must present at least one seminar.
Prerequisite: Graduate status
PHCL - 6700 PHARMACOLOGY III: CNS AND CARDIOVASCULAR/RENAL PHARMACOLOGY
[3 hours] The pharmacology of central nervous
system active agents such as the opiod analgesics and alcohol continues from PHCL 5720. Agents acting on the cardiovascular and renal
systems are discussed. Prerequisite: PHCL 5720
PHCL - 6720 PHARMACOLOGY IV; CHEMOTHERAPEUTICS
[3 hours] The pharmacology of anti-infective chemotherapeutic agents is
presented. Issues such as the mechanism of antimicrobial action, disposition, resistance, and problems attending the use of antimicrobial
drugs will be discussed. Prerequisite: PHCL 6700
PHCL - 6770 TOXICOLOGICAL RISK ASSESSMENT
[3 hours] Study of human health risk assessment on NRC paradigm of: hazard
identification, effects characterization, exposure characterization, and risk characterization. Topics to be covered
(pharmacokinetic/pharmacodynamic modeling, etc.) are designed to provide the student with the tools necessary to conduct quantitative risk
assessment. Prerequisite: PHCL 5760 or PHCL 6150
PHCL - 6900 M.S. THESIS RESEARCH IN PHARMACOLOGY
[1 - 6 hours] M.S. thesis research in pharmacology. Prerequisite:
Graduate status
PHCL - 6920 M.S. THESIS RESEARCH IN PHARMACOLOGY
[1 - 6 hours] M.S. thesis research in pharmacology Prerequisite:
Graduate status
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