PHCL - PHARMACOLOGY

PHCL - 2220   DRUGS, MEDICINE AND SOCIETY
[3 hours]  The course provides the student with a general knowledge of drugs including why drugs act, how drugs act, where drugs act, and the general pharmacology of specific classes of drugs, e.g. �the pill�, central nervous system active agents, etc.

PHCL - 2600   FUNCTIONAL ANATOMY AND PATHOPHYSIOLOGY I
[4 hours]  A study of functional anatomy, physiology and pathophysiology to serve as background for the  understanding of the action of drugs.  Prerequisite: CHEM 1230, 1240, 1280, 1290; BIOL 2150, 2160, 2170 and 2180  Corequisite: 2nd year standing

PHCL - 2620   FUNCTIONAL ANATOMY AND PATHOPHYSIOLOGY II
[4 hours]  A continuation of PHCL 2600.  Prerequisite: PHCL 2600

PHCL - 3700   PHARMACOLOGY I:  PRINCIPLES OF PHARMACOLOGY, AUTONOMIC PHARMACOLOGY AND NON-STEROIDAL ANTI-INFLAMMATORY AGENTS AND RELATED PHARMACOLOGY
[3 hours]  An introduction to the principles of pharmacology and the pharmacology of the autonomic nervous system. Non-steroidal anti inflammatory agents are also discussed.  Prerequisite: Admission to professional division  Corequisite: MBC 3550, MBC 3310

PHCL - 3720   PHARMACOLOGY II: ENDOCRINE AND CNS PHARMACOLOGY
[3 hours]  The pharmacology of drugs acting upon the endocrine and reproductive systems will be discussed, followed by a treatment of drugs used in the management of sleep disorders, for anxiety, for affective illness, for schizophrenia, and for seizure disorders.  Prerequisite: PHCL 3700  Corequisite: MBC 3560

PHCL - 4140   INTERPRETATION OF PHARMACEUTICAL DATA
[3 hours]  A course designed to emphasize the interpretation of statistical data as it appears in the literature which is related to pharmacy.  The concepts of statistics will be discussed.  Experimental design as well as appropriateness of analytical methodology and conclusions will be stressed.  Prerequisite: Admission to the professional division, or upper division, or consent of instructor.

PHCL - 4150   BIOPHARMACEUTICS AND PHARMACOKINETICS
[4 hours]  Application of kinetic models to the processes of drug absorption, distribution, biotransformation, and excretion.  The influence of dosage form and physiology on these processes.  Application of pharmacokinetic principles to clinical situations.  Prerequisite: PHPR 3080, Consent of Instructor

PHCL - 4300   SELECTED TOPICS IN PHARMACOLOGY
[2 hours]  The pharmacology of selected classes of agents will be discussed. Discussions will include the pharmacology of: Drugs used to treat asthma, antihistamines, drugs used to treat migraine, drugs to manage movement disorders, local anesthetics, and antineoplastic agents.  Prerequisite: Completion of PHCL 4700

PHCL - 4600    EPIDEMIOLOGY
[4 hours]  This course is intended to provide fundamental concepts of epidemiology and its basic research methods. The course is designed as a prerequisite for pharmacoepidemiology.   Prerequisite: 4th year standing or permission of instructor

PHCL - 4620  PHARMACOEPIDEMIOLOGY
[4 hours]  This course is intended to give an overview of and terminology commonly used in  pharmacoepidemiology and to teach students how to review and comprehend pharmacoepidemiologic studies. Prerequisite: PHCL 4610, or permission of instructor. Corequisite: PHCL 5140

PHCL - 4700  PHARMACOLOGY III: CNS AND CARDIOVASCULAR PHARMACOLOGY
[3 hours]  The pharmacology of central nervous system active agents such as opioid analgesics and alcohol. Continues from PHCL 3720. Agents acting on the cardiovascular and renal systems are discussed. Prerequisite: PHCL 3720

PHCL - 4720   PHARMACOLOGY IV: CHEMOTHERAPEUTIC AGENTS
[3 hours]  The pharmacology of anti-infective chemotherapeutic agents is presented.  Issues such as the mechanism of antimicrobial action, disposition, resistance, and problems attending the use of antimicrobial drugs will be discussed.  Prerequisite: PHCL 4700, 4150, MBC 3600

PHCL - 4730  TOXICOLOGY I
[3 hours]  A synopsis of the basic elements of toxicology including dose-response, lethal dose-50, margin of safety, mechanisms of toxicity, and nature of toxic injuries including mutagenesis and carcinogenesis.  Treatments for poisonings will not be treated in detail (see PHCL 4740)  Prerequisite: 4th yr standing in the College; PHCL 4700 for B.S. Pharm, MBC 4300 for B.S. Pharm; permission of instructor for non-Pharmacy majors. Co-requisite: PHCL 3700.

PHCL - 4740   INTRODUCTION TO CLINICAL TOXICOLOGY
[2 hours]  An introduction to the diagnosis and treatment of human poisoning and risk assessment will be discussed utilizing the lecture and case presentation format.  Prerequisite: 4th or 5th yr. standing in the College; PHCL 4700

PHCL - 4750  TOXICOLOGY II
[3 hours]  This course provides the students with an overview of environmental toxicology, which emphasizes both air and water pollution. It also reviews the applications of different areas of toxicology, such as food toxicology emphasizing the safety standards of food and methods of evaluation of food safety, analytic toxicology and its applications in forensic toxicology, and occupational toxicology, emphasizing the health effects of industrial chemicals on workers and also the permissible levels of these chemicals in the work place. Prerequisite: Completion of PHCL 4730 or permission of instructor.

PHCL - 4760  TOXICOKINETICS
[3 hours]  The theory and practice of using kinetic principles to model the time course of toxic chemicals in the body and in the environment. Relation of the chemical time course to negative outcomes and application to risk assessment. Hands-on practice with kinetic analysis methods and software. Prerequisite: 4th year standing; permission for non-pharmacy students

PHCL - 4770   TOXICOLOGICAL RISK ASSESSMENT
[3 hours]  Study of human health risk assessment based on National Research Council paradigm.  Topics (pharmacokinetic/dynamic modeling, etc.) are designed to provide the student with the tools necessary to conduct quantitative risk assessment. Prerequisite: PHCL 4760 or PHCL 4150 or consent of instructor

PHCL - 4780   PRACTICUM IN TOXICOLOGY
[3 hours]  In this experiential course students will acquire practical knowledge and hands-on experience in the areas of pharmacology and/or toxicology by working at private or government laboratories.   Prerequisite: fourth year student in good standing in BSPS program. All required courses in the first 3 years of the PTOX major must have been successfully completed.

PHCL - 4800   HUMAN-XENOBIOTIC INTERACTIONS
[3 hours]  This course will summarize the ways in which xenobiotics affect the human condition both in the context of therapeutic benefit and also chemically-induced diseases. Existing strategies for developing xenobiotics to control disease and for managing xenobiotics in order to limit disease will be discussed.   Prerequisite: PHCL 3700, 3720, 4700, 4730, 4140

PHCL - 4850   DRUG DISPOSITION
[2 hours]  The influence of host factors such as disease states, drug-drug interactions, and environmental chemical exposure will be discussed within the framework of basic principles of drug absorption, distribution, metabolism, and excretion.  Prerequisite: PHCL 4150

PHCL - 4900   HONORS SEMINAR IN PHARMACOLOGY
[1-3 hours]  An examination of a specific question in the context of the primary literature in pharmacology and in the context of the student�s own findings based on his/her thesis research.  Prerequisite: 4th yr. standing;  3.3 overall GPA;  3.5 GPA in Pharmacology/or instructor consent

PHCL - 4910   PROBLEMS IN PHARMACOLOGY
[1 - 3 hours]  An examination of a specific question in pharmacology which can be answered through application of experimental work.  Prerequisite: Consent of Instructor

PHCL - 4960   HONORS THESIS IN PHARMACOLOGY
[2-5 hours]  An examination of a specific question in pharmacology which can be answered through application of experimental work.  Prerequisite: 4th. yr. standing;  3.3 GPA overall;  3.5 GPA in Pharmacology/or consent of instructor

PHCL - 5140   INTERPRETATION OF PHARMACEUTICAL DATA
[2 hours]  A course designed to emphasize the presentation, analysis and interpretation of data in the pharmaceutical sciences.  The concepts of statistics will be discussed.  Experimental design as well as appropriateness of analytical methodology and conclusions will be stressed.  Prerequisite: Admission to the graduate program or consent of instructor.

PHCL - 5300   SELECTED TOPICS IN PHARMACOLOGY
[2 hours]  This course discusses the pharmacodynamics and pharmacotherapeutics of selected classes of pharmacologic agents. The pathophysiology of the disease states for which these agents are commonly employed will be described.  Prerequisite: PHCL 5700

PHCL - 5600    RESEARCH METHODS IN EPIDEMIOLOGY
[4 hours]  This course is intended to provide fundamental concepts of epidemiology and its basic research methods. The course is designed as a prerequisite for pharmacoepidemiology.   Prerequisite: 4th year standing or permission of instructor

PHCL - 5620  PHARMACOEPIDEMIOLOGY
[4 hours]  This course is intended to give an overview of and terminology commonly used in  pharmacoepidemiology and to teach students how to review and comprehend pharmacoepidemiologic studies. Prerequisite: PHCL 4610, or permission of instructor. Corequisite: PHCL 5140

PHCL - 5700   PHARMACOLOGY  I �PRINCIPLES OF PHARMACOLOGY, AUTONOMIC PHARMACOLOGY AND NON-STEROIDAL ANTI-INFLAMMATORY AGENTS AND RELATED PHARMACOLOGY
[3 hours]  An introduction to the principles of pharmacology and the pharmacology of the autonomic system. Non-steroidal anti inflammatory agents are also discussed.  Prerequisite: Admission to the Graduate Program

PHCL - 5720   PHARMACOLOGY II:  ENDOCRINE AND CNS PHARMACOLOGY
[3 hours]  The pharmacology of drugs acting upon the endocrine and reproductive systems will be discussed, followed by a treatment of drugs used in the management of sleep disorders, for anxiety, for affective illness, for schizophrenia, and for seizure disorders.  Prerequisite: PHCL 5700

PHCL - 5730  TOXICOLOGY I
[3 hours]  This course reviews the basic elements of toxicology. It includes those principles most frequently involved in a full understanding of toxicologic events, such as dose-response, lethal dose-50 (LD50) and margin of safety. It also identifies toxic chemicals and their systemic sites and mechanisms of action. Finally, this course provides information about the kinds of toxic injuries produced in specific organs or systems and the toxic agents that produce these effects. Information about the possible management of some cases of intoxication or poisoning by some agents will be briefly reviewed.  Prerequisite: PHCL 5700

PHCL - 5750  TOXICOLOGY II
[3 hours]  This course provides the students with an overview of environmental toxicology, which emphasizes both air and water pollution. It also reviews the applications of different areas of toxicology, such as food toxicology emphasizing the safety standards of food and methods of evaluation of food safety, analytic toxicology and its applications in forensic toxicology, and occupational toxicology, emphasizing the health effects of industrial chemicals on workers and also the permissible levels of these chemicals in the work place. Prerequisite: Completion of PHCL 5730 or permission of instructor.

PHCL - 5760  TOXICOKINETICS
[3 hours]  The theory and practice of using kinetic principles to model the time course of toxic chemicals in the body and in the environment. Relation of the chemical time course to negative outcomes and application to risk assessment. Hands-on practice with kinetic analysis methods and software. Prerequisite: Graduate status

PHCL - 5900   DRUG DISPOSITION
[2 hours]  The influence of host factors such as disease states, drug-drug interactions, and environmental chemical exposure will be discussed within the framework of basic principles of drug absorption, distribution, metabolism, and excretion.  Prerequisite: Graduate status

PHCL - 5990   PROBLEMS IN PHARMACOLOGY
[1 - 6 hours]  Tutorial or directed individual research in pharmacology.  Prerequisite: Graduate status

PHCL - 6150   ADVANCED PHARMACOKINETICS
[2 hours]  A study of the mathematical models describing the time course of drugs in the body and their application in the interpretation of in vivo data.  Prerequisite: Admission to the graduate program; or consent of instructor

PHCL - 6600   SEMINAR IN PHARMACOLOGY
[1 hour]  Pharmacology students will attend seminar presentations offered through the seminar/colloquia programs in the departments of Biology and Chemistry and in the College of Pharmacy, and must present at least one seminar.  Prerequisite: Graduate status

PHCL - 6700   PHARMACOLOGY III:  CNS AND CARDIOVASCULAR/RENAL PHARMACOLOGY
[3 hours]  The pharmacology of central nervous system active agents such as the opiod analgesics and alcohol continues from PHCL 5720.  Agents acting on the cardiovascular and renal systems are discussed.  Prerequisite: PHCL 5720

PHCL - 6720   PHARMACOLOGY IV; CHEMOTHERAPEUTICS
[3 hours]  The pharmacology of anti-infective chemotherapeutic agents is presented.  Issues such as the mechanism of antimicrobial action, disposition, resistance, and problems attending the use of antimicrobial drugs will be discussed. Prerequisite: PHCL 6700

PHCL - 6770   TOXICOLOGICAL RISK ASSESSMENT
[3 hours]  Study of human health risk assessment on NRC paradigm of:  hazard identification, effects characterization, exposure characterization, and risk characterization.  Topics to be covered (pharmacokinetic/pharmacodynamic modeling, etc.) are designed to provide the student with the tools necessary to conduct quantitative risk assessment.  Prerequisite: PHCL 5760 or PHCL 6150

PHCL - 6900   M.S. THESIS RESEARCH IN PHARMACOLOGY
[1 - 6 hours]  M.S. thesis research in pharmacology.  Prerequisite: Graduate status

PHCL - 6920   M.S. THESIS RESEARCH IN PHARMACOLOGY
[1 - 6 hours]  M.S. thesis research in pharmacology  Prerequisite: Graduate status

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Last Updated: 5/5/14