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Admission Requirements
Industrial Pharmacy Option
Master of Science in Medicinal Chemistry
Doctor of Philosophy in Medicinal Chemistry

Master of Science in Pharmaceutical Sciences
Graduate Programs

Degrees Offered

The Master of Science in pharmaceutical sciences degree is designed to prepare an individual for responsibilities in professional practice, the pharmaceutical industry and scientific research beyond those possible with a baccalaureate.

Although a single degree is conferred, specialization is possible in that the curriculum is organized into three distinct disciplines, referred to here as "options". Applicants must select the program of study (option) they wish to pursue.

The requirements for the Master of Science in pharmaceutical sciences degree differ according to the option.  The minimum didactic course work for the industrial pharmacy major is 30 semester hours, for the pharmacology/toxicology major 36 semester hours and for the pharmacy administration major 32 semester hours.  In addition, each major requires a minimum of 6 semester hours of thesis research.

Admission Requirements

In general, a baccalaureate in the sciences is required for admission, although applicants possessing other bachelor’s degrees will be considered if the latter represent adequate preparation. Certain options and graduate courses require undergraduate preparation as prerequisites, and this preparation should be completed as soon as possible upon admission to the Graduate School. The total time required for completion of the graduate program leading to the Master of Science in pharmaceutical sciences degree will depend upon the preparation of the student entering the Graduate School. Normally two years of study and research are required.

The admission requirements of the Graduate School of the University apply. The basic requirement is a 2.7 (on a 4.0 scale) GPA on all undergraduate work leading to the bachelor’s degree. Applicants having less than a 2.7 GPA on all undergraduate work will be considered for admission if other criteria for estimation of potential success in graduate studies are positive.

Each student must submit three copies of transcripts, one of which must be official and show all post-secondary academic work and degrees granted, three letters of recommendation from college faculty members acquainted with the applicant’s character and ability, and scores from the aptitude portion of the GRE.

International students are required to take the TOEFL, which will be given in their own country by the Educational Testing Service.

Normally, acceptance will be decided by April 1 for admission during the following fall semester. The priority deadline for completed applications is January 15th. Complete applications received by this deadline will be considered for admission. Applications received after the January 15th deadline may also be considered, if positions are available in a program. International students are encouraged to submit applications one month prior to the stated deadline to allow for delays in international correspondence.

Curriculum and Options – M.S. Program in Pharmaceutical Science

The options available to graduate students are pharmacology/toxicology, administrative pharmacy and industrial pharmacy.

Pharmacology/Toxicology option: A minimum of 36 semester hours of courses plus a minimum of 6 thesis credit hours are required for the degree.

Undergraduate courses required (or their equivalents):

CHEM                  3710                  Physical Chemistry for the Biosciences I                           3

CHEM                  3720                  Physical Chemistry for the Biosciences II                          3

MATH                  1750                  Calculus for the Life Sciences I                                        4

MATH                  1760                  Calculus for the Life Sciences II                                       3

MBC                  3310                  Medicinal Chemistry I: Drug Action and Design                   3

MBC                  3320                  Medicinal Chemistry II: Drug Targeting

                                                      to Receptors                                                               3

MBC                  4300                  Medicinal Chemistry III: Chemotherapy and

                                                      Immunotherapy                                                          3

PHCL                  2600                  Functional Anatomy and Pathophysiology I                       4

PHCL                  2620                  Functional Anatomy and Pathophysiology II                      4

 

Graduate courses required:

PHCL                  5140                  Interpretation of Pharmaceutical Data                                         2

PHCL                  5700                  Pharmacology I-Principles of Pharmacology,

                                                      Autonomic Pharmacology and Non-Steroidal

                                                      Anti-inflammatory Agents and Related

                                                      Pharmacology                                                                       3

PHCL                  5720                  Pharmacology II: Endocrine and CNS Pharmacology                    3

PHCL                  5730                  Toxicology I                                                                             3

PHCL                  5760                  Toxicokinetics                                                                          3

or

PHCL                  6600                  Seminar in Pharmacology                                                        1-2

PHCL                  6700                  Pharmacology III: CNS and Cardiovascular/

                                                      Renal Pharmacology                                                            3

PHCL                  6720                  Pharmacology IV: Chemotherapeutics                                      3

PHCL                  6900*                  M.S. Thesis Research in Pharmacology                                  1-6

PHCL                  6920*                  M.S. Thesis Research in Pharmacology                                  1-6

 

*6 credit hours are the required minimum, more than 6 credit hours can be taken.

 

Elective course work may be selected from the following***:

PHCL                  5630                  Cancer Chemotherapy (highly recommended)                              3

PHCL                  5750                  Toxicology II                                                                             3

PHCL                  5990**                  Problems in Pharmacology (highly recommended)                   6-18

 

**May replace PHCL-5700, 5720, 5730, 6700, 6720, and 5760 if these were taken at UT at the undergraduate level as PHCL-3700, 3730, 4730, 4810, 4820 and 4760, respectively, and a grade of B- or above received for the course.

 

MBC                  6100                  Advanced Immunology                                                             2

MBC                  6550                  Biochemistry                                                                           4

MBC                  5620                  Biochemical techniques                                                            2

MBC                   6800                  Methods in Biotechnology                                                        3

 

***Other electives may be recommended by the department graduate committee.

Administrative Pharmacy option: A minimum of 32 semester hours of course work plus a minimum of 6 thesis hours are needed for the degree.

 

MKTG                  5410                  Marketing Systems                                                                        3

PHPR                   5260                  Pharmacy & Healthcare Administration I                                          2

PHPR                  5520                  Pharmaceutical Marketing and Management                                     3

PHPR                  5590                  Readings in Health Care Access and Cultural
                                                  Competence                                                                                   2

PHPR                  5610                  Pharmacoeconomics and Outcomes Research I                                 2

PHPR                   6600                  Seminar in Administrative Pharmacy                                               1

PHPR                   6520                  Analysis of the Pharmaceutical Environment                                    2

PHPR                  6530                  Research Methods in Pharmacy Practice                                           2

PHPR                  6960                  Thesis Research in Pharmacy                                                         1-6*

RESM                  5110                  Statistics and Quantitative Methods I                                             3

RESM                  6120                  Statistics and Quantitative Methods II                                            3

**Track courses                  As approved by advisor                                                      minimum of 9 credit hours

 

*A minimum of 6 credit hours of Thesis Research In Pharmacy is required.

 

**Students enrolled in this option must select a Track Focus after the first semester.

 

Program Tracks, with approved track courses are as follows:

 

1. Business Administration

  • BUAD 6100 Accounting for Strategic Decisions                                                 3
  • BUAD 6200 Financial Systems                                                                        3
  • BUAD 6300 Strategic Marketing & Analysis                                                      3
  • BUAD 6400 Results-Based Management                                                          3
  • BUAD 6500 International business                                                                  3
  • BUAD 6600 Supply Chain Management                                                           3
  • BUAD 6800 Information Technology & E-Business                                           3
  • BUAD 6900 Strategic management Capstone                                                  3

 

 

2. Outcomes Research-Track Courses

  • PUBH 6600 Health Behavior                                                                        3
  • PUBH 6460 Health Promotion Programs                                                        3
  • PUBH 601 Public Health Epidemiology                                                          3
  • PUBH 603 Advanced Epidemiology                                                               3
  • PUBH 611 Categorical Data Analysis                                                            3

 

3. Pharmacoeconomics-Track Courses

  • PHPR 5620 Pharmacoeconomics and Outcomes II                                     3
  • ECON 5750 Health Economics                                                                 3
  • ECON 5810 Econometrics Models and Methods I                                       3
  • ECON 5820 Econometrics Models and Methods II                                      3
  • ECON 5830 Econometrics Models and Methods III                                    3

 

4. Social Behavior Sciences- Track Courses

  • PUBH 6600 Health Behavior                                                                        3
  • PUBH 6460 Health Promotion Programs                                                       3
  • RESM 6220 Measurement I                                                                         3
  • RESM 6230 Measurement II                                                                        3

 

Other Track Courses or electives may be approved by the department graduate committee

Industrial Pharmacy option: A minimum of 30 semester hours of course work and a minimum of 6 credit hours of thesis work is required for the degree.

Undergraduate courses required:

Courses will be evaluated for students with a B.S. in pharmacy, Pharm.D. or B.S.P.S. degree.

MBC                                    3550                  Physiological Chemistry I: Structure and Function
                                                                   of Biological Macromolecules                                                               3

MBC                                    3560                  Physiological Chemistry II: Chemical Regulation
                                                                   of Cells and Organisms                                                                       3

PHPR                                    3070                  Pharmaceutics and Pharmaceutical Technology I
  
                                                                                         and

PHPR                                    3080                  Pharmaceutics and Pharmaceutical Technology II

                                                                                          or

CHEM                                    3710                  Physical Chemistry for the Biosciences I and

CHEM                                    3720                  Physical Chemistry for the Biosciences II and

CHEM                                    3730                  Physical Chemistry I                                                                    8-9

PHPR                                    4520                  Pharmaceutical Management and Marketing                                     3

PHPR                                    4550                  Analysis of the Pharmaceutical Environment                                    3

Graduate required courses:

CHEM                  6300                  Advanced Analytical Chemistry                                                                      2-4

CHEM                  6310                  Separation Methods                                                                                     2-4

EEES                  5710                  Advanced Biostatistics                                                                                    4

PHCL                  6150                  Advanced Pharmacokinetics                                                                            2

PHPR                  5690                  Dosage Form Design                                                                                      3

PHPR                  5700                  Equilibrium Phenomenon                                                                                2

PHPR                  5720                  Pharmaceutical Rate Processes                                                                       3

PHPR                  6600                  Seminar in Administrative Pharmacy                                                               1

PHPR                  6850                  Product Development                                                                                     3

PHPR                  6960                  M.S. Thesis Research in Pharmacy                                                                  6

 

Additional course work may be selected from the following:

CHEM                  6320                  Characterization of Condensed Phases and Surfaces                                     2-4

CHEM                  6330                  Spectroscopic Methods and Analysis of Spectra                                            2-4

CHEM                  6720                  Physical Chemistry of Material Transformations                                            2-4

CHEM                  6810                  Materials Science I                                                                                     4

CHEM                  6820                  Materials Science II                                                                                    4

CHEM                  6980                  Special Topics in Chemistry                                                                       2-4

PHCL                  5760                  Toxicokinetics                                                                                            3

PHPR                  5680                  Parenteral Manufacturing                                                                            2

PHPR                  5710                  Selected Topics in Pharmaceutical Technology                                            2-4

PHPR                  5990                  Problems in Pharmacy Practice                                                                  1-6

PHPR                  6530                  Research Methods in Pharmacy Practice                                                       3

PHPR                  6610                  Seminar I                                                                                                 1

 

Applicants for the administrative pharmacy and industrial pharmacy options who possess a B.S. in pharmacy, Pharm.D. or bachelor of science in pharmaceutical sciences degree from an ACPE-accredited institution will be given preference for admission into those options. International applicants must have earned pharmacy degrees from their home institutions.

Master of Science in Medicinal Chemistry

Admission Requirements

Satisfactory completion of a bachelor’s degree in chemistry, biology, pharmacy or a related discipline is required. It is assumed the undergraduate training will include differential and integral calculus, college physics, a one-year course in general and inorganic chemistry including a laboratory, a one-year course in organic chemistry including a laboratory, and training in analytical chemistry. An undergraduate course in physical chemistry is recommended.

The admission requirements of the Graduate School of the University apply.

Degree Requirements

Master’s students need to complete the following courses as partial fulfillment of their requirement for an M.S. degree:

MBC                  5100                  Research Practices in Medicinal Chemistry                                                 1

MBC                  5620                  Biochemical Techniques                                                                           2

MBC                  5900                  Medicinal Chemistry Seminar (4 hours required)                                        1

MBC                  6190                  Advanced Medicinal Chemistry                                                                  4

MBC                  6200                  Biomedicinal Chemistry                                                                            4

MBC                  6550                  Biochemistry                                                                                           4

MBC                  6960                  M.S. Thesis Research in

                                                      Medicinal Chemistry (6 hours required)                                              1-15

Other 5000- to 6000-level courses as advised

 

In addition, the following items also must be completed:

  1. Minimum of 30 semester hours of graduate credit, of which no more than six hours are counted from the category of M.S. thesis or Ph. D. dissertation research (MBC 6960/8960)
  2. Preparation of a written M.S. thesis based upon the results of an original research investigation performed by the student during the M.S. program at The University of Toledo.
  3. Successful oral defense of the thesis before the thesis advisory committee (consisting of the thesis adviser and two other members) and presentation of the results of the thesis research in a seminar before the department of medicinal and biological chemistry.
  4. Acceptance of this thesis by the M.S. thesis adviser and the thesis advisory committee.
  5. Maintenance of a GPA of 3.0 or higher.

Doctor of Philosophy in Medicinal Chemistry

Admission Requirements

Satisfactory completion of a bachelor’s degree in chemistry, biology, pharmacy or a related discipline is required. It is assumed that the undergraduate training will include differential and integral calculus, college physics, a one-year course in general and inorganic chemistry including a laboratory, a one-year course in organic chemistry including a laboratory, and training in analytical chemistry. An undergraduate course in physical chemistry is recommended.

The ability to excel in graduate studies and research must be evident based on grades from undergraduate studies, recommendations from college faculty, results from standardized aptitude and achievement examinations (Graduate Record Examination), and performance in research and independent study.

Students with M.S. degrees in medicinal chemistry or related fields may be admitted directly to the Ph.D. program. Students without M.S. degrees may be admitted directly to the Ph.D. program, but must take 30 credits at the master’s level prior to accruing doctoral level credits.

Ph.D. students need to complete the following courses as partial fulfillment of their requirement for a Ph.D. degree. Additional graduate courses (5000 to 8000 level) may be required, as advised during the development of each student’s plan of study.

MBC                  5100/7100                  Research Practices in Medicinal Chemistry                                      1

MBC                  5620/7620                  Biochemical Techniques                                                                2

MBC                   5900/7900                  Medicinal Chemistry Seminar (6 hours required)                            1

MBC                  6190/8190                  Advanced Medicinal Chemistry                                                      4

MBC                  6200/8200                  Biomedicinal Chemistry                                                                 4

MBC                  6300/8300                  Biomedicinal Chemistry Laboratory I                                              4

MBC                  6310/8310                  Biomedicinal Chemistry Laboratory II                                             4

MBC                  6550/8550                  Biochemistry                                                                                4

MBC                   8960                  Ph.D. Dissertation Research in Medicinal

                                    Chemistry (30 hours required)                                                                           1-15

 

Select 8 hours in chemistry, biology, or medicinal and biological chemistry:

Chemistry Courses

CHEM                  6330            Spectroscopic Methods                                                                               2-4

CHEM                  6400/8400                  Advanced Organic Chemistry                                                       2-4

CHEM                  6410/8410                  Organic Synthesis                                                                       2-4

CHEM                  6420                  Physical Organic Chemistry                                                                   2-4

CHEM                  6510/8510                  Protein Chemistry                                                                        2-4

CHEM                  6520/8520                  Enzymology                                                                                2-4

CHEM                  6530/8530                  Nucleic Acid Chemistry                                                                2-4

Biology Courses

BIOL                  6010/8010                  Advanced Molecular Biology                                                            4

BIOL                  6020/8020                  Advanced Molecular Biology Laboratory                                           3

BIOL                  6090/8090                  Advanced Cell Biology                                                                    4

BIOL                  6100/8100                  Research Methodology: Cell and Molecular Biology                           3

Medicinal and Biological Chemistry Courses

MBC                  5380/7380                  Medicinal and Poisonous Plants                                                        3

MBC                  6100/8100                  Advanced Immunology                                                                    2

MBC                  6800/8800                  Methods in Biotechnology                                                                3

Other MBC courses as advised

 

In addition, all students must satisfy the following:

  1. Minimum of 60 semester hours of graduate credit beyond the master’s level (see master of science in medicinal chemistry), including a minimum of 15 hours of courses, laboratories and seminars (exclusive of dissertation research) and a minimum of 30 hours of Ph.D. dissertation research.
  2. Satisfactory overall performance on a written qualifying examination covering graduate-level medicinal chemistry, biochemistry and either organic chemistry or advanced cell/molecular biology.
  3. Selection of a doctoral research adviser, preparation of an acceptable written Ph.D. dissertation proposal in consultation with the adviser, and the satisfactory oral defense of the proposal before the dissertation advisory committee. The written qualifying examination and the defense of the dissertation proposal will constitute the examination requirements necessary for advancement to candidacy for the Ph.D. in medicinal chemistry. The chair of the doctoral dissertation advisory committee will be the student’s doctoral research adviser. The dissertation advisory committee will consist of two additional faculty plus one member from outside the student’s department or college.
  4. Subsequent to admission to candidacy for the Ph.D. degree, the student is expected to spend a minimum of two semesters in full-time study at The University of Toledo.
  5.  Preparation of a Ph.D. dissertation based on the results of an original research investigation performed by the student during his/her Ph.D. program at The University of Toledo.
  6.  Successful oral defense of the dissertation before the dissertation advisory committee and presentation of the results of the dissertation research in a seminar before the department of medicinal and biological chemistry.
  7.  Acceptance of the dissertation by the Ph.D. dissertation adviser and the dissertation advisory committee.
  8. Maintenance of a GPA of 3.0 or higher.

Doctor of Pharmacy Degree Programs

The Doctor of Pharmacy degree for applicants having, among other qualifications, a B.S. in Pharmacy, is unavailable at this time.

Combined Pharm.D. – Ph.D. in Medicinal Chemistry Program

Admission Requirements

Students who are admitted to both programs separately may pursue both degrees concomitantly.

Program Requirements

Although the requirements for both programs will be met, there is some overlap and flexibility, allowing a student to complete graduate-level requirements for both degrees in four to four and a half years. In general terms, students will follow the sequence for the Pharm.D. curriculum during the first four semesters, taking one graduate-level medicinal chemistry course each semester. In the fifth semester, students will take the required Pharm.D. clerkships, plus the two-hour seminar, with at least one clerkship rotation involving a research experience. The Ph.D. requirement for MBC 6550 (Biochemistry) will be waived. Beginning with sixth semester (summer following the second year), students will complete the requirements for the Ph.D. in medicinal chemistry.

Last Updated: 6/26/15