The University of Toledo

Research - Clinical Research - Multiple Sclerosis

Research Home

Clinical Research - Neurology      Epilepsy      Headache      Multiple Sclerosis      Stroke      Parkinson's Disease

Grant Funded Research - Neurology

MULTIPLE SCLEROSIS

For questions about becoming involved with our multiple sclerosis studies, please contact:
Andrea Korsnack, RN, Certified Clinical Research Coordinator * 419-383-3801 * andrea.korsnack@utoledo.edu

The University of Toledo Multiple Sclerosis Clinic maintains clinical affiliation with the National Multiple Sclerosis Society (www.nationalMSsociety.org), and participates in NIH- and pharmaceutically supported clinical trials for the treatment of multiple sclerosis.

Clinical Trials:

The University of Toledo participated in the following clinical trials (enrollment complete):

CombiRx Trial:  A multi-center, randomized, blinded study of Avonex^® alone, Copaxone^® alone, or a Combination^® of both Avonex^® and Copaxone^® in subjects with relapsing-remitting multiple sclerosis who have never received disease modifying therapy (NIH; Mt. Sinai School of Medicine, New York, NY). 

A 24-month, double-blind, placebo-controlled, parallel-group study comparing the efficacy and safety of 0.5 mg and 1.25 mg Fingolimod (FTY 720) administered once daily versus placebo in patients with relapsing-remitting multiple sclerosis (Novartis).

For current multiple sclerosis clinical trials at the University of Toledo, search clinicaltrials.gov using the key words “multiple sclerosis AND Toledo.” 

Basic science research:

Additional projects include translational research collaborations to evaluate potential new treatments for MS in experimental autoimmune encephalomyelitis (EAE) with:

     Anthony Quinn, PhD, Associate Professor, Department of Biology (http://www.utoledo.edu/nsm/bio/research/quinn.html);

     Miles Hacker, PhD, Professor, Department of Pharmacology (http://www.utoledo.edu/pharmacy/depts/pharmacology/faculty-mhacker.html).

Recent presentations/publications:

Poster presentations: 

Kiraly A, Quinn A, Gunning W, Koffman B, Hacker  M.  "Treatment with a novel aza-anthrapyrazole prevents MOG-induced EAE" for the 15^th annual meeting of ACTRIMS, San Antonio, Texas, June 5, 2010.

Koffman BM, Mutgi S, Crooks R, Khuder S, Herial NA.  “Impact on oral health in multiple sclerosis and epilepsy:  a neurology clinic survey” for the 24^th annual meeting of the Consortium of Multiple Sclerosis Centers (CMSC), San Antonio, Texas, June 2-5, 2010.