Division of Medical Physics

Radiation Biology

UT HSC Medical Physics Course MPHY6160/8160 (CRN: 27965/27971) 
Spring semester 2019

 Class meeting time:   Monday 1:30 PM - 4:15 PM
(*Fridays, 4:30 – 6:30 PM for TC lectures
**Tuesdays, 5:00 – 7:00 PM for SS lectures)

 Class meeting place:

Ruppert Center, Suit K, 0005A
(DCC 2nd floor conference room for SS/TC lectures)

 Textbook:

Radiobiology for the Radiologist, 7th edition
Eric J. Hall, Amato Giaccia; Lippincott, Williams & Wilkins Co, Philadelphia, PA 

 Instructors:  Diana Shvydka, E. Ishmael Parsai, David Elliott, Krishna Reddy, Siddharth Saraiya

 Grades: Midterm - 50%, Final exam - 50%

 

Syllabus:

Date

Prof.

Topic(s)

Chapters

 14 Jan

EIP

Physics & Chemistry of Radiation Absorption

1

 24 Jan

DS

DNA Strand Breaks; Chromosome Aberrations; Cell Survival Curves

2, 3

 28 Jan

EIP

Oxygen Effects; Re-oxygenation; Linear Energy Transfer; Relative Biological Effectiveness 

6, 7

 4 Feb

DS

Radiosensitivity and Cell Age in the Mitotic Cycle; Fractionated Radiation and the Dose-Rate Effect

4, 5

 *15 Feb

TC

Effects of Total Body Irradiation; Radiation Cataractogenesis; Radiation Carcinogenesis

8, 10, 13 

 18 Feb

EIP

Heritable Effects of Radiation; Effects of Radiation on the Embryo and Fetus 

11, 12

 **26 Feb

SS

  Cancer Biology 

18

 Week of  Mar 4th

 

SPRING BREAK

 

 11 Mar

DS

MIDTERM EXAMINATION

1-8, 10-13, 18

 18 Mar

DS

Dose-Response Relationships; Normal Tissue Responses 

19, 20

 25 Mar

EIP

Diagnostic Imaging; Nuclear Medicine; Radiation Risk vs. Benefit; Radiation Protection

15, 16, 17

 1 Apr

DS

Model Tumor Systems; Tumor Kinetics 

21, 22

 *12 Apr

TC

Time, Dose and Fractionation in Clinical Radiotherapy; Newer & Less Common Radiation Modalities  

23, 24, 25 

 **16 Apr

SS

Radioprotectors; Radiosensitizers;  Chemotherapy Agents

9, 26, 27

 22 Apr

DS

HyperthermiaPredictive Assays; Radiation and Immunotherapy

28

 29 Apr

DS

FINAL EXAMINATION

9, 15-17, 21, 22, 23-28

Last Updated: 1/12/19