FacultyJon R. Kirchhoff
Distinguished University Professor
Office: WO 2265
Phone: (419) 530-1515
Fax: (419) 530-4033
B.A. 1979 State University of New York at Cortland
Ph.D. 1985 Purdue University
Postdoctoral Fellow: 1985-1989 University of Cincinnati
Research in my group focuses on developing analytical methodology that enhances selectivity and sensitivity for chemical measurements, especially those involving detection of analytes in complex mixtures or at trace levels. Numerous approaches to enhance selectivity are employed such as the high efficiency of capillary electrophoresis (CE) separations, the development of electrochemical-based sensor devices with analyte specific recognition elements, or the combination of CE with microelectrode sensors as the detector. With all of these approaches, we push the limits of detection and extend those levels at which detection and quantitation can be confidently made.
Research projects are interdisciplinary in nature, spanning many subdisciplines of chemistry and impacting all areas of chemistry. Graduate and undergraduate students have utilized CE to develop separations for isomeric o-quinones and chiral drug compounds, fabricated bio- and electrocatalytic electrodes for the measurement of the neurotransmitter acetylcholine and its metabolic precursor choline, as well as thiols at the sub femtomole level, developed assays for investigating variations in choline uptake in brain tissue by cholinomimetic inhibitors of choline transport, discovered novel chemical vapor deposition and nanomaterials techniques to fabricate disk and ring-disk microelectrodes, specific sensor devices, and new optically transparent electrodes for spectroelectrochemical measurements, and synthesized and characterized novel luminescent rhenium(II) transition metal complexes and cadmium selenide quantum dot structures. The details of many of these projects can be found in the publications listed on this web site.