College of Pharmacy and Pharmaceutical Sciences

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Main and Health Science Campuses
Wolfe Hall 1227 (MC)
Phone: 419.530.2010
Frederic and Mary Wolfe Center 155 (HSC)
Phone: 419.383.1904 pharmacy@utoledo.edu

Research and Scholarly Activity

Research Interests

  • Solubility and Thermodynamic Parameters of Therapeutic Pharmaceutical Agents
  • Physico-Chemical Properties of Therapeutic Agents in Relation to Their Mechanism of Action and Their Molecular Orbital Spatial Configurations
  • Physico-Chemical Properties of Tablets
  • Design and Evaluation of Contemporary Dosage Forms
  • Parenteral Dosage Form Stability and Evaluation
  • Suspension Theory and Stability
  • Stability of Pharmaceuticals and Their Related Excipients in the Solid State
  • Transdermal Absorption of Selected Pharmaceutical Agents and the Use of Enhancers to Facilitate Their Absorption
  • Mathematical Modeling of Pharmaceutical Systems to Explain Their Deviance from Ideal
  • Suspension Stability in the Presence of Pharmaceutical Adjuvants
  • The Stability of Simple Drug Moieties in the Solid State
  • The Formulation and Stability of New Oral Liquid Pediatric Dosage Forms Used in the Treatment of Acute and Chronic Pediatric/Geriatric Diseases
  • The Evaporative Process from a Kinetic and Thermal Viewpoint
  • The Formulation of Products for Human Hair and Their Effects
  • Stability of Pharmaceutical Agents in the Solid State
  • Transdermal Adsorption of Pharmaceutically Important Agents
  • Characterization of Volatile Components Used in Aromatherapy, Perfumery, and Flavors
  • Characterization of Fully Formulated Commercial Tablets
  • Characterization of Polymorphic Materials
  • Characterization of Water Present in Solids, Solutions, and Suspensions
  • Eutectic and Solid Solution Formation
  • Directed undergraduate research projects in the area of: Dosage Form Design and Evaluation for five (5) students since 1973, Solubility and Drug Availability for Commercial "Generic Equivalents" of OTC Products', 1976; Dye Stability for five (5) students, 1986-88; I.V. Admixture Stability for three (3) students, 1988; 1990; 1991; Aminoglycoside Dosing Models for two (2) students, 1989; River Sedimentation 1991, Validation of Stokes' Law 1991.
Research Activities
  • Research advisor in the 'Science Mentor Program' - a joint UT-Toledo Board of Education Summer Science Research Program for 10th and 11th grade high school students who receive college credit and research experience (students supervised): 1985(1); 1986(2); 1987(1); 1988(3)
  • Research advisor in the Research Apprenticeship in Science Program - a program to continue the Research Mentor Program sponsored by Toledo Edison (students supervised): 1990 (1); 1991 (1); 1992 (1); 1993 (3); 1994 (1); 1995 (3)
  • Thesis advisory committee for M.S. students in pharmaceutics and hospital pharmacy option 1980-85
  • Research advisor for M.S. students in The Industrial Pharmacy Option 1985-present
  • Research advisor for BSPS students in the Pharmaceutics Option 2005-present
Undergraduate Research
  • Honors Thesis
    1. Andrea Schroeder Knapp - Co-Advisor with V. Mauro PharmD. - Thesis research entitled - The In-Syringe Compatibility of Toradol and Other Post-Surgical Injectables, May 1992
Graduate Research

M.Sc. Thesis Advisory Committee for:
  1. Mr. John Mroczkowski, MS. 1981 - Thesis entitled: Influence of Some Formulation Factors on the Intramuscular Absorption of Gentamicin.
  2. Ms. Alma N Malanyaon, MS Chemistry Dept. - in progress
  3. Mrs. Sahaja Rao, MS December 1996, Department of Chemistry, Thesis entitled "Thermal Decomposition Study of Selected Calcium Carboxylates Both in the Presence and also in the Absence of Excipients"
  4. Mr. Yuanwen Wu, Chemistry Department, MS in progress
  5. Ms. Caroline O'Connell, Chemistry Department, MS June 1998, Department of Chemistry, Thesis entitled "Thermal Decomposition Studies of Selected Fatty Substances and the Substances Used to Preserve Them"
  6. Ms. Pauline Phang, Chemistry Department, MS in progress
M.S. Theses
  1. Mr. James K. Smith, MS 1987 - project entitled "An Update on Particulate Contamination: Does the Supplier of D5/NS for Injection Make a Difference"
  2. Mr. Faroog A. Patel, MS 1988 - project entitled: "An Investigation of Suspensions of China Clay and Kaolin N.F"
  3. Mr. VyKuntam Uppala, MS 1990 - Thesis entitled "The Behavior of Concentrate Calcium Carbonate Suspensions"
  4. Mr. Kaushik Dani, MS 1990 - Thesis entitled "The Stability of Ascorbic Acid in Tablet Formulations Using Thermal Analytical Techniques"
  5. Mr. Rajiu Haribhakt, MS 1990 - Thesis entitled "The Formulation and Stability of Oral Liquid Pediatric Dosage Forms: Acetazolamide"
  6. Ms. Shahnaz S. Tata, MS 1990 - Thesis entitled "An Investigation of the Hindered Settling Behavior of Concentrated Magnesium Hydroxide Slurries"
  7. Mr. Gireesh V. Gupchup, MS 1990 - Thesis entitled "An Investigation Into the Solid State Behavior of Aspirin in Pharmaceutical Tablet Mixtures Using Thermoanalytical Techniques"
  8. Mr. Maddasudin Puddapedi, MS 1991 - Thesis entitled "The Formulation and Stability of Oral Liquid Pediatric Dosage Forms: Procainamide and Hydralazine"
  9. Ms. Sujata Swaminathan, MS 1991 - Thesis entitled "The Determination of Stability Constants for the Complexation of Dextrose and Glycine in Intravenous Fluids with Transition Metals"
  10. Ms. A. Savitri Murthy, MS 1991 - Thesis entitled "Investigation of Sedimentation Parameters of Concentrated Aluminum Hydroxide Slurries"
  11. Mr. Norool-Huda, S.A.F., MS 1992 - Thesis entitled "Investigation and Characterization of Model Carbon Systems in Concentrated Slurries"
  12. Mr. Nipun Dawar, MS 1992 - Thesis entitled "Formulation Development and Stability of Alopurinol and Rifampin Suspensions"
  13. Ms. Divya Gangwal, MS 1992 - Thesis entitled "Sedimentation Behavior of Concentrated Aluminum Hydroxide Suspensions"
  14. Ms. Nandini Konar, MS 1992 - Thesis entitled "Characterization of Cholesterol in Kidney and Gallstone Formation"
  15. Ms. Weeriyit Chirarutsami, MS 1992 - Thesis entitled "An Investigation of the Dehydration of Magnesium Hydroxide Paste"
  16. Ms. Nuthanun Kusolmanomai, MS 1993- Thesis entitled "The Behavior pf Magnesium Hydroxide Suspensions in the Never Dried State and Flocculated with Polymer Flocculants"
  17. Ms. Dipoli Roy, MS 1993 - Thesis entitled "The Determination of Stability Constants for the Complexation of Dextrose and the Amino Acids Arginine and Serine"
  18. Mr. Sanjay Rayathatha, MS 1993 - Thesis entitled "Comparison of Isothermal and Non-Isothermal Stability Studies for Hydralazine Pediatric Syrup"
  19. Mr. Shyam Vangala, MS 1993 - Thesis entitled "The Formulation and Stability of Oral Liquid Pediatric Dosage Forms: Spironalactone and Metronidazole"
  20. Mr. Manish Agrawal, MS 1994 - Thesis entitled "The Stability of Erythrocin Dye"
  21. Ms. Dolly Patel, MS 1994 - Thesis entitled "An Investigation Into The Use of Thermal Analysis In Pharmaceutical Applications"
  22. Ms. Supattra Ochacharion, MS 1994 - Thesis entitled "The Investigation of Concentrated Suspensions of Aluminum Hydroxide, Magnesium Hydroxide and Calcium Carbonate"
  23. Ms. Kavita Nair, MS 1994 - Thesis entitled "An Investigation Into the Thermal Decomposition of Dolomite As Influenced By The Effects of Grinding and The Presence of Excipients Using Thermal Analysis and Associated Techniques"
  24. Mr. Pavan Heda, MS 1994 - Thesis entitled "The Stability of Sodium Bicarbonate and Other Formulation Ingredients in Toothpaste"
  25. Mr. Abhijit Chakraborty, MS 1994, Thesis entitled "Solubility and Thermodynamic Parameters of Monosubstituted Benzoic Acid s"
  26. Mr. Madhusudanrao Kothapalli, MS 1995, Thesis entitled "Development of a Stable Analytical Method for Sodium Citrate" and "Stability of Levothyroxine Pediatric Oral Solution"
  27. Mr. Vineet Chaudry, MS 1995, Thesis entitled "The Characterization of Human Hair and the Development of a New Non-Interactive Hair Straightening Formulation"
  28. Ms. Ping Tong, MS 1995, Thesis entitled "An Investigation of Concentrated Suspensions of Calcium Phosphate and Calcium Oxalate and Their Relationship to Gall Stone Formation"
  29. Mr. Aditya Prendse, MS 1995, Thesis entitled "Hindered Settling Studies Using 'Never-Dried' Suspensions"
  30. Mr. Hanumanthrao V. Ramachandruni, MS 1995, Thesis entitled "The Formulation and Stability of Oral Liquid Pediatric Dosage Forms: Captropril and Atenolol"
  31. Ms. Supaporn Lerdkanchanaporn, MS 1995, Thesis entitled "Investigation Into the Shelf-Life Stability of Pharmaceutical Products Containing Ascorbic Acid"
  32. Mr. Isam Tahboub, MS 1995, Thesis entitled " Investigation of a Carbon Black Model in Aqueous Suspension With Respect to Changes in Reactivity Parameters".
  33. Mr. Mohamad Mazin Chwiki, MS 1996, Thesis entitled "An Investigation of the Effect of Microwave Heating on Thermal Stability and Hindered Settling"
  34. Mr. Yichun Sun, MS 1996,Thesis entitled "Study of the Evaporation of Benzaldehyde from PEG Base"
  35. Ms. Monica Motwani, MS 1996, Thesis entitled "Investigation and Characterization of the Components of a Cosmetic Cream Using Thermogravimetry"
  36. Mr. Youssef, Bassam, MS December 1996, thesis entitled "The Application of Thermal Analysis to the Study of the Behavior of Concentrated Aqueous Suspensions or Kaolin and Talc"
  37. Ms. Lalitha Arikapudi, MS 1997, thesis entitled "Thermal Characterization and Accelerated Stability Testing of an Extemporaneous Syrup Formulation of Metoprolol Tartrate"
  38. Mr. Anirban Basu, MS 1997, thesis entitled "Mathematical Modeling of Hindered Settling Behavior with Respect to Concentrated Magnesium Carbonate Suspensions"
  39. Ms. Kranthi Yelamanchely, MS 1997 Thesis entitled: "Treatment Base Compositional Influence on the In Vitro Diffusion of Methyl Salicylate and Effect of the Design of the Diffusion Cell on the Amount of Drug Released."
  40. Mr. Bhanu Kalvakota MS 1997, thesis entitled "The Thermal Stability of Aspirin in the Presence of Magnesium Stearate"
  41. Ms Li Shen, MS August 1998 thesis entitled "Solid State Stability of Medium Chain Length Fatty Acids with Pharmaceutical Excipients", currently enrolled in the Ph.D. program Chemistry Department University of Toledo
  42. Ms. Lihua Zhang, MS December 1998, thesis entitled "Solid State Stability of Medium Chain Length Fatty Acids with Pharmaceutical Excipients", currently employed at Oread, Lawrence, Kansas
  43. Ms. Xu Zheng, MS June 1998, thesis entitled "An In Vitro Diffusion Study of Atropine Across Shed Snake Skin Used As A Model Membrane System"
  44. Mr. Yu-Hsiu Cheng, MS August 1999, thesis entitled "A Thermal Analysis Study of Methyl Salicylate"
  45. Ms. Chunhong Gu, MS December 1999, thesis entitled A Stability Study of Ascorbic Acid Using Thermal Analysis Techniques"
  46. Ms. Yu-I Huang, MS December 1999, thesis entitled "A Thermal Analysis Study of Captopril and Its Selected Excipients"
  47. Mr. Mahesh N. Samtani, August 2000, thesis entitled: "Thermal Analysis of Ground Dolomite."
  48. Mr. Sachin Mittal, August 2000, thesis entitled: "Characterization of Yohimbine HCl Using Analytical Physical, Transdermal and Excipient Compatibility Studies."
  49. Ms. Nasreen Khan, August 2000, thesis entitled: "Thermal Decomposition Studies on Selected Magnesium Hydroxy Carbonate Samples."
  50. Mr. Rahul Malhotra, August 2000, thesis entitled: "Effects of Compaction and Presence of Excipients on Thermal Decomposition of Magnesium Hydroxide."
  51. Mr. Kostuv Chatterjee, August 2000, thesis entitled: "Calculation of Vapor Pressure Curves for Selected Benzoic Acid Derivatives Using Thermogravimetry."
  52. Mr. Aditya Tatavarti, August 2000, thesis entitled: "The Application of Thermal Analysis to Study the Behavior of Selected Pharmaceutically Import and Polymers and Polymer Additives."
  53. Mr. Nitin Kaila, MS August 2001, thesis entitled "Formulation Development and Stability of an Extemporaneous Suspension prepared from Commercially available Dapsone tablets "
  54. Ms. Anasuya Hazra, MS August 2001,thesis entitled ‘Characterization and Kinetics of Essential Oils and Their Key Components Using Thermal Analytical Techniques".
  55. Mr. Murali Duvvuri , MS August 2001,thesis entitled "Comparison of Commercially available Saw Palmetto Products against USP’s Nutritional Standards and Other Criteria."
  56. Ms. Divya Menon, MS August 2001,thesis entitled "A Thermal Analysis Study of Tableting of Nicotinic acid."
  57. Mr. Anuj Kumar, MS August 2001,thesis entitled "An In-Vitro Biological Modelling of Polymethacrylate Microspheres Incorporating Hyoscyamine Hemisulfate."
  58. Mr. Parthiv Vora, MS August 2001,theis entitled "Characterization and Thermal Behavior of Vitamins: Nicotinic acid and Nicotinamide using Thermogravimetry.
  59. Ms. Simin Hassannejad Tabasi, MS August 2001,thesis entitled," The Stability and Thermal Behavior of Calcium Oxalate in the presence of Cholesterol to Explain the formation of Kidney stones."
  60. Ms. Qian Zhu, MS August 2001, thesis entitled "A Hindred Settling Behavior Study for Calcium Hydrogen Phosphate Aqueous Suspensions-Particle Size analysis and Their Associate Liquid Determined Using Thermal analysis."
  61. Ms. Farah Khan, MS August 2001,thesis entitled "Thermal Dehydration of Epsom salts and D. Gluconic acid salt."
  62. Ms. Akansha Vora, MS December 2001, Thesis entitled: "Thermal Stability of Folic Acid and Associated Excipients."
  63. Mr. Ravishankar Vedula - MS, December 2001. Thesis entitled "A Study of the Effect of Particle Size and Other Parameters on the Sedimentation of Concentrated Pumice Suspensions." Currently employed at the Pharmaceutical Industry.
  64. Mr. Yuantao Wang - MS, December 2001. Thesis entitled "Suspension Stability of Magnesium Trisilicate in Various Pharmaceutical Dispension Systems." Currently employed in a Biotech firm in NJ.
  65. Mr. Shouvik Roy - MS June 2002. Thesis entitled "investigation of the Stability and InVitro Release Profile of Sulfamerazine Polymorphs from Directly Compressed Tablets - A Preformulation Study." Currently enrolled in the PhD program at the University of Colorado.
  66. Ms. Renuka Thirumangalathu - MS, August 2002. Thesis entitled" Formulation and Modeling of In-vitro Release Kinetics of Phenylpropenolamine Hydrochloride Microspheres." Currently enrolled in the PhD program at the University of Colorado.
  67. Ms. Kavitha Bhasi - MS, August 2002. Thesis entitled "A Study of the Sedimentation of Pumice Using Carbopol Sodium Alginate and Gelatin as Dispensing Agents." Currently enrolled in the PhD program at the State University of New York at Buffalo.
  68. Mr. Nagarajan Thyagarajapuram - MS, August 2002. Thesis entitled "Analytical Method Development of Amiodarone Hydrochloride: Formulation and Stability Studies of Extemporaneous Suspensions of Amiodarone Hydrochloride." Currently enrolled in the PhD program at the University of Kansas.
  69. Ms. Sarita Kaushik - MS, August 2002. Thesis entitled "Formulation Development and Stability Testing of Extemporaneously Prepared Mexiletine Hydrochloride Solution." Currently seeking employment in the pharmaceutical industry.
  70. Ms. Pallabi Mitra - MS, May 2003. Thesis entitled "Analytical method development, formulation development, and stability testing of an extemporaneously prepared propylthiouracil suspension." Currently enrolled in the Ph.D. program at the University of Kansas
  71. Mr. Pradyot Nandi - MS, May 2003. Thesis entitled "Thermal Characterization And Kinetics Of Essential Oils And Their Major Constituents Used In Aromatherapy." Currently enrolled in the Ph.D. program at the University of Kansas
  72. Mr. Rajesh Vadlapatla - MS, May 2003. Thesis entitled "Solid State Cbhacterization of Anhydrous and Hydrous Forms of Aminophylline and Their In-Vitro Drug Release atternsN." Currently enrolled in the Ph.D. program at the University of Arkansas.
  73. Mr. Sumit Majundar - MS May 2003. Thesis entitled "Thermal Characterization of the moisture interaction of the Microcrystalline Cellulose grades in a model Pharmaceutical formulation and their effect on the drug release behavior." Currently enrolled in the PhD program at the University of Kansas
  74. Mr. Sandipan Sinha - MS, May 2003. Thesis entitled" Preparation and Evaluation of the Amorphous Form of Sulfapyridine-the Effect of Relative Humidity, Excipients and Temperature" Currently enrolled in the PhD program at the University of Kansas
  75. Mr. Lalit M. Oberroi - MS, May 2004. Thesis entitled "Formulation of a fast acting ibuprofen suspension by using nicotinamide as a hydrotropic agent- application of DSC, spectroscopy and microscopy in assessment of the type of interaction." Currently enrolled in the Ph.D. program at the University of Arkansas.
  76. Ms. Paroma Chakabarty - MS, May 2004. Thesis entitled "Evaluation of the Crystalline Properties and Dissolution Profiles of Tolbutamide: Effect of Experimental Factors and Solid Dispersions" Currently enrolled in the Ph.D. Program at the University of Minnesota.
  77. Ms. Bhaswati DattaChowdhury - MS, May 2004. Thesis entitled "Application of Theoretical Models in the Crystallization Kinetics of Pharmaceuticals from the Amorphous State." Currently enrolled in the Ph.D. program at the University of Kansas.
  78. Ms. Marcia A. Williams - MS May 2004. Thesis entitled "A Comparison of the Disintegration Properties of Three Starches and a Super-Disintegrant-A novel Approach", Returned to Jamaica to resume teaching duties in Pharmaceutics at her home University.
  79. Ms. Jayeeta Sen - MS, May 2005. Thesis entitled "Synergistic Effects of Ternary Systems on the Release Profiles of Naproxen and Tolbutamide " Currently employed in a pharmaceutical company in India
  80. Mr. Amanda Jones - MS, May 2005. Thesis entitled "Pharmaceutical Eutectics: Formation, Evaluation and Relevance in Preformulation Studies Using Thermal Analytical Techniques." Currently enrolled in the Ph.D. program at the Ohio State University
  81. Mr. Pinaki Basu - MS, May 2005. Thesis entitled "Crystalliation Kinetics of Amorphous Ketoconazole" Currently enrolled in the Ph.D. program at the University of Colorado
  82. Mr. Indranil Rao - MS May 2005. Thesis entitled "A Vaporization Study of Vegetable Oils and Their Constituents: Construction of Vapor Pressure Curves and Kinetics of Degradation by Thermogravimetry" Currently enrolled in the PhD program at the University of Buffalo
  83. Ms. Jinal Desai - MS, August 2005. Thesis entitled "Development of Controlled Released Formulations of Dimenhydrinate Using Ethyl Cellulose: Application of the Solid Dispersion and Wet Granulation Technique" Currently employed in a biotech firm in New Jersey
  84. Mr. Ping Ma - MS August 2006 Thesis entitled " "
Ph.D. Theses
  1. Mr. Olusola Sunday Ogundiram, Department of Chemical Engineering, Ph.D. 1991, Thesis entitled: Application of Membranes in Chemical Reaction Systems
  2. Mr. John D. Skelton Jr., Department of Chemistry, Ph.D., 1993, Thesis entitled: Micellar Behavior and Particle Size Determination of Surfactants and Cholesterol Aggregates
  3. Mr. William Jones III, Chemistry Dept. – did not finish
  4. Ms. Poonam Aggrawal, Department of Chemistry, Ph.D. March 1997, Thesis entitled "Physicochemical Characteristics of Starch and Modified Starch"
  5. Ms. Olga Shulga, Department of Chemistry, MS 2001, Ph.D. 2005
  6. Ms. Shamtell F. Wright, Department of Chemistry, MS 2004

Consultantships

  • North American Science Associates, Northwood, Ohio (1975-1982)
  • Owens Illinois, Toledo, Ohio, Professional Affairs Division (1976) - aid provided in the development of a chart to be used by pharmacists to determine packaging requirements for compendial drug products
  • Owens Illinois, Toledo, Ohio, Glass Research Division (1978) - assistance provided in determining quality of glass and glass particles sloughed into solution for parenteral containers so as to meet U.S.P. requirements
  • Consultations with hospital pharmacists (1975-2000) concerning:
  • I.V. Admixture procedures, compatibilities and policies
  • Equipment utilization and availability
  • Consultation with community pharmacists (1974-2000) concerning:
  • Extemporaneous Prescription Compounding problems
  • Chemical and equipment availability
  • Utilization of University facilities for the compounding of basic medicaments which were not possible within the retail setting
  • Dr. Morton Schulak, Podiatrist, Toledo, Ohio (1982-1985) - development of podiatric dosage forms containing parachlorometaxylenol (PCMX)
  • Gottfried Medical Products Co., Toledo, Ohio (1982) - investigation of legal definition of the term "generic equivalent" as it applies to medical products in order to prepare a company position paper on same
  • Men's Garden Club of Toledo, Toledo, Ohio (1982) - development of a suspension system for the application of a widely used rooting compound for field testing purposes
  • Owens Illinois, Toledo, Ohio, Marketing Division (1982) - aid provided in the development of a confidential marketing report proposed for a new product
  • Oral-Mate, Inc., Swanton, Ohio (1983) - development of a Novel Fluoride Delivery System for their patented invention
  • B.E.C. Laboratories, Toledo, Ohio (1983) - Dosage Form Design and Development
  • Elder Pharmaceutical Company, Bryan, Ohio (1983) - development and evaluation of a dissolution methodology for their psoralen derivatives for submission to the U.S.P.
  • North American Science Associates, Northwood, Ohio (1983-1985) - Formal contract as pharmaceutical consultant - drug stability; dosage form stability; U.S.P. evaluation
  • ARCO Corp., Bryan, Ohio (1986) - development of an industrial burn ointment.
  • St. Vincent's School of Anesthesiology, St. Vincent Medical Center, Toledo, Ohio (1985-1987) taught pharmacology to Registered Nurse Student Anesthetists.
  • Falhgren & Swink, Toledo, Ohio (1989) - aid in defining reuse of prescription vials for local glass company.
  • Pharmaceutical Services & Technologies, Lambertville, Michigan (1987-present).
  • R.Ph. Procare, Lambertville, Michigan (1985-present).

Grants

1.  

Title:

The Education of Undergraduate & Graduate Thermal Analysts

 

Agency:  

Mettler-Toledo Thermal Analysis Education Grant In Honor of Prof. Edith Turi

 

PI:

Kenneth S. Alexander, PhD

 

Co-Pi:

Alan T. Riga, PhD

 

Amount:

$135,000; Date submitted - March 10, 2003

 

Status:

Not funded - July 2003

 

   

2.

Title:

Structure Based Drug Design

 

Agency:

Ohio BRTT Program 2003

 

PI:

Paul Erhardt PhD (UT); J. Karn Ph.D. (CWRU); A. Gudkov Ph.D. (TCCF)

 

Co-Pi:

College of Pharmacy Faculty including K.S. Alexander

 

Amount:

$600,000; Date submitted - March 10, 2003

 

Status:

Not funded

 

   

3.

Title:

Considereing ADMET During Drug Design and Development

 

Agency:

Ohio Hayes Investment Fund Program 2003

 

PI:

Paul Erhardt PhD; J. Karn Ph.D. (CWRU); A. Gudkov Ph.D. (TCCF)

 

Co-Pi:

College of Pharmacy Faculty including K.S. Alexander

 

Amount:

$500,000; Date submitted - March 10, 2003

 

Status:

Not funded

 

   

4.

Title:

The Education of Undergraduate & Graduate Thermal Analysts

 

Agency:

Mettler-Toledo Thermal Analysis Education Grant In Honor of Prof. Edith Turi

 

PI:

Kenneth S. Alexander, PhD

 

Amount:

$158,000; Date submitted - March 10, 2004

 

Status:

funded - August 2004 Equipment Received 1/19/2005

 

Monographs and books

  1. Dispensing of Medication, 9th Edition, Robert E. King, Editor, Chapter 11: Apprisal of Product Quality, pp 221 -257, 1984, Mack Publishing Co., Easton PA
  2. ICS Learning Systems, Scranton, PA , Copyright 1997 ICS Intangibles Holding Company - Development of the following Study Units to be incorporated into a self-paced Pharmacy Technician Course to be commercially distributed:
    1. Pharmaceutical Dispensing III: Liquid Dosage Forms by K.S. Alexander and D. Berlekamp
    2. Pharmaceutical Dispensing IV: Topical Dosage Forms by K.S. Alexander and D. Berlekamp
    3. Pharmaceutical Dispensing V: Miscellaneous Dose Forms by K.S. Alexander and D. Berlekamp
  3. Pharmaceutical Excipients published by APhA. Publications, submitted 10/92, accepted 4/1/93, January 1995:
    1. Canola Oil
    2. Corn Oil
  4. Pharmaceutical Excipients published by APhA. Publications, submitted 10/97, accepted 11/1/97, to be published January 1999:
    1. Canola Oil
    2. Corn Oil
    3. Cottonseed Oil
  5. Handbook of Pharmaceutical Excipients, 5th Edition published January 2005
    1. Canola Oil
    2. Corn Oil
    3. Cottonseed Oil
  6. American Drug Index, Billups, N.F., Editor, Facts & Comparisons, St. Louis, MO, Editor of two tables: Container and Storage Requirements for U.S.P. Compendial Sterile Dosage Forms; and, Container Requirements for USP/NP Compendial Dosage Forms and Nutritional Supplements (1985-present).
  7. Instrumental Analysis Handbook, Walter Kluwer Press,  Chapter 15, Thermal Analysis – Chapter submitted September 15th 2003 – Galley’s received July 15th 2004 and resubmitted for publication July 30th, 2004.  Published December 2004.

Papers Presented

  1. Solubility Profiles for Barbiturates in n-Alkanols - APhA Convention, Houston, Texas, 1972

  2. Molecular Orbital Calculations for Barbiturate Moieties, APhA Convention, Houston, Texas, 1972

  3. Solubility of Parabens in l-Alkanols II: Thermodynamic Parameters, APhA Convention, Academy of Pharmaceutical Sciences, Basic Pharmaceutics Section, San Francisco, April 12, 1975

  4. The Impact of a Mandatory Sterile Product Technology Course in the Undergraduate Curriculum: presented to the Section of Teachers of Pharmacy, Council of Faculties, American Association of Colleges of Pharmacy, Seattle, Washington, August 9, 1977

  5. Hyperalimentation Component Compatibility Prediction, invited presentation to Graduate Students and Faculty, May 13, 1985, Duquesne University, Pittsburgh, Pennsylvania

  6. An Investigation of China Clay and Kaolin NF: Is There A Difference by Patel, F. and Alexander, K., presented to the 18th Annual Pharmaceutics Graduate Research Meeting, June 16, 1986, Chicago, Illinois

  7. Color is The Difference - presented to participants in 'Science Experiences for Junior High School Students, October 8, 1986, The University of Toledo

  8. Thermal Analysis Methodologies for Product Stability Prediction by Dani, K.J. and Alexander, K., presented to the 19th Annual Pharmaceutics Graduate Student Research Meeting, June 25, 1987, Ann Arbor, Michigan

  9. Uppala V., Alexander, K.S., and Dollimore, D. "Interpretation of Calcium Carbonate Suspensions in Terms of Permeability" presented at the Twentieth Annual Pharmaceutical Graduate Student Research Meeting, The University of Missouri-Kansas City, Kansas City, Missouri, June 10, 1988

  10. Alexander, K.S., Azizi, J., Dollimore, D. and Patel, F. "An Interpretation of the Sedimentation Behavior of Pharmaceutical Kaolin and Other Kaolin Preparations in Aqueous Environments" presented as a refereed invited paper at the 8th Pharmaceutical Technology Conference, Beach Plaza Hotel, Monte Carlo, Monaco, March 29-31, 1989

  11. Gupchup G.V., Alexander, K.S., Azizi, J., Dollimore, D. and Wilburn, F.W., "A Thermal Analysis Study of Aspirin Tablets Subjected to Disintegration in Aqueous Environment" presented at the Twenty-First Annual Pharmaceutical Graduate Student Research Meeting, The University of Minnesota, Minneapolis, Minnesota, June 18, 1989

  12. Tata, S.S., Alexander, K.S., Dollimore, D. and Wilburn, F.W., "A Study of the Behavior of Magnesium Hydroxide Slurries in Various Environments" presented at the Twenty-First Annual Pharmaceutical Graduate Student Research Meeting, The University of Minnesota, Minneapolis, Minnesota, June 18, 1989

  13. Haribhakti, R.P., Alexander, K.S. and Packer, G.A., "Formulation Development and Stability of Pediatric Acetazolamide Suspensions" presented at the Twenty-First Annual Pharmaceutical Graduate Student Research Meeting, The University of Minnesota, Minneapolis, Minnesota, June 18, 1989

  14. Uppala, V., Alexander, K.S. and Dollimore, D., "The Relationship Between Steinour's Parameter A and Richardson-Zaki Parameter n and Its Evaluation Using Sedimenting Suspensions" presented at the Twenty-First Annual Pharmaceutical Graduate Student Research Meeting, The University of Minnesota, Minneapolis, Minnesota, June 18, 1989

  15. Swaminathan, S., Alexander, K., Parker, G.A., Swartz, E. and Paulock, J., "Determination of the Metal-Binding Properties of Dextrose and Glycine," presented at the 22nd Annual Pharmaceutics Graduate Research Meeting, Ohio State University, Columbus, Ohio, June 15-17, 1990

  16. Murthy, A.S., Alexander, K. and Dollimore, D. "Sedimentation Behavior of Concentrated Aluminum Hydroxide Slurries," presented at the 22nd Annual Pharmaceutics Graduate Research Meeting, Ohio State University, Columbus, Ohio, June 15-17, 1990

  17. Madhusudhan, P., Alexander, K.S., and Parker, G.A. "Compatibility Studies on Hydralazine Hydrochloride", podium presentation, The 23rd Annual Pharmaceutics Graduate Student Research Meeting, University of Wisconsin, Madison, WI June 13-15, 1991

  18. Murthy, A.S., Alexander, K.S., Dollimore, D. and Tata, S.S. "Investigation of Sedimentation Parameters of Concentrated Aluminum and Magnesium Hydroxide Slurries", podium presentation, 23rd Central Regional Meeting and 24th Great Lakes Regional Meeting of the American Chemical Society, University Place Conference Center, Indiana University, Purdue University at Indianapolis, Indiana, May 29-31, 1991

  19. Konar, N., Alexander, K.S. and Dollimore, D. "The Flocculating Action of Cholesterol on the 'In-Situ' Precipitation of Calcium Oxalate", podium presentation, 23rd Annual Pharmaceutics Graduate Student Research Meeting, University of Wisconsin, Madison, Wisconsin, June 13-15, 1991

  20. Gangwal, D., Alexander, K.S. and Dollimore, D. "Hindered Settling of Alumina in the Never Dried State", podium presentation, 23rd Annual Pharmaceutics Graduate Student Research Meeting, University of Wisconsin, Madison, Wisconsin, June 13-15, 1991

  21. Noorul-Huda, Alexander, K.S. and Dollimore, D. "Investigation of Model Carbon Systems in Concentrated Slurries and Their Characterization", podium presentation, 23rd Annual Pharmaceutics Graduate Student Research Meeting, University of Wisconsin, Madison, Wisconsin, June 13-15, 1991

  22. Konar, N., Swaminathin, S., Alexander, K.S. and Dollimore, D. "The Characterization of Calcium Oxalate Precipitated in the Presence of Cholesterol", podium presentation, 50th Ann. Anachem Symposium, Botsford Inn, Farmington, Michigan, November 7, 1991

  23. Gangwal, D., Murthy, A.S., Alexander, K.S. and Dollimore, D. "Comparison of Parameters of Concentrated Aluminum Hydroxide Slurries Prepared from Dried Gel and From Preparations in the ‘Never Dried State’", podium presentation, 50th Ann, Anachem Symposium, Botsford Inn, Farmington, Michigan, November 7, 1991

  24. Noorul-Huda, Alexander, K.S., Dollimore, D. and Bensch, K. "Characterization of Carbon Black Dispersions at High Concentration", podium presentation, 50th Ann, Anachem Symposium, Botsford Inn, Farmington, Michigan, November 7, 1991

  25. Alexander, K.S., Dollimore, D., and Murthy, A.S., "Investigation of Sedimentation Parameters of Concentrated Akluminum Hydroxide Slurries", podium presentation, 11th Pharmaceutical Technology Conference, University of Manchester Institute of Science and Technology, Manchester, UK, April 8, 1992

  26. The following were presented at The Fourteenth Annual Undergraduate Research Seminar, West Virginia University School of Pharmacy, Morgantown, West Virginia, October 9, 1992
    1. Kositchaivat, P., Alexander, K.S. and Dollimore, D., "The Effect of Kaolin and Ionic Strength on a Free Falling Substance"
    2. Tan, S.L., Alexander, K.S., Dollimore, D. and Skelton, J.D., "An Improved Method for Calculating Flox Size for Pharmaceutical Suspensions From Bulk Volume Determinations"
    3. Potter, J.A., Alexander, K.S. & Dollimore, D., "Verification of Stokes’ Law"
  27. Pavan Heda, Dollimore, D., Alexander, K.S. and Chen, D., "Thermal Decomposition of Sodium Bicarbonate" presented as a podium presentation, 25th Annual Pharmaceutics Graduate Student Research Meeting, Purdue University, West Lafayette, Indiana, June 10-12, 1993

  28. Chakraborty, A., Alexander, K.S., Alexander, K.A. and Dollimore, D., "Solubility Studies for o-, m-, and p- Substituted Carboxylic Acid Cogeners", podium presentation, 25th Annual Pharmaceutics Graduate Student Research Meeting, Purdue University, West Lafayette, Indiana, June 10-12, 1993

  29. Nair, K., Dollimore, D., Alexander, K.S. and Chen, D., "Thermal Decomposition of Dolomite" presented as a podium presentation, 25th Annual Pharmaceutics Graduate Student Research Meeting, Purdue University, West Lafayette, Indiana, June 10-12, 1993

  30. Vangala, S. and, Alexander, K.S., "The Formulation Development and Chemical Stability of Extemporaneously Prepared Metronidazole Suspension" as a podium presentation, 25th Annual Pharmaceutics Graduate Student Research Meeting, Purdue University, West Lafayette, Indiana, June 10-12, 1993.

  31. Huynh, T.C., Alexander, K.S. and Dollimore D. "Titration Method to Determine Porosity in Pharmaceutical Powders" presented at The Fifteenth Annual Undergraduate Research Seminar, West Virginia University School of Pharmacy, Morgantown, West Virginia, October 18, 1993.

  32. The following papers were presented by Dr. Alexander at the Annual Meeting of the Fine Particle Society, April 3, 1998 at the Hotel Continental, Dallas TX:
    1. Heda, P.K., Dollimore, D. And Alexander, K.S., "An Assessment of the Solid State Reactivity of Sodium Bicarbonate in the Presence of Solid Dental Excipients Using Thermal Analysis."
    2. Dollimore, D., Heda, P.K., Alexander, K.S. and Chen, D. "Single Pan DTA and Heating Curve on an SDT 2960 Simultaneous TGA/DTA Equipment."
    3. Heda, P.K., Dollimore, D., Alexander, K.S., Law, E. and Bicknell, P. "A Novel Approach in Relating the Solid State Reactivity of a Substance to Its Particle Size and Surface Area Using Thermal Analysis and Associated Techniques."
  33. Alexander, K.S. and Dollimore, D., "The Use of Hindered Settling Data to Evaluate Particle Size or Floc Size and the Effect of Particle-Liquid Association on Such Sizes" a short course presented at the Annual Meeting of the Fine Particle Society, Hotel Continental, Dallas TX, April 3, 1998.

  34. Shen, L., Alexander, K.S. and Dollimore, D., "A Thermal Analysis Study of Lactic Acid," a podium presentation at the North American Thermal Analysis Society Meeting, Cleveland, OH September 12-15, 1998.

  35. Shen, L., Alexander, K.S. and Dollimore, D., "A Thermal Analysis Study of Long Chain Fatty Acids," a podium presentation at the North American Thermal Analysis Society Meeting, Cleveland, OH September 12-15, 1998.

  36. Burnham, L.K., Dollimore, D. and Alexander, K.S."A Rising Temperature Kinetic Model to Describe Complex Reaction Kinetics of a Drug: Procainamide Hydrochloride", a podium presentation at the 26th Conference of the North American Thermal Analysis Society, Cleveland, Ohio, September 13-15, 1998

  37. Samtani, M., Dollimore, D., and Alexander, K. "Thermal Decomposition of Dolomite in an Atmosphere of Carbon Dioxide," podium presentation at the 28th Conference of the North American Thermal Analysis Society, Orlando, FL, September 16-19, 2000

  38. Samtani, M., Dollimore, D., and Alexander, K. "Comparison of Dolomite Decomposition Kinetics with Related Carbonates and the Effect of Procedural Variables on Its Kinetic Parameters," podium presentation at the 28th Conference of the North American Thermal Analysis Society, Orlando, FL, September 16-19, 2000

  39. Chatterjee, K., Dollimore, D., Alexander, K. "Calculation of Vapor Pressure Curves for Hydroxy Benzoic Acid Compounds Using Thermogravimetry" a podium presentation at the 28th Conference of the North American Thermal Analysis Society, Orlando, FL, September 16-19, 2000

  40. Anasuya Hazra, Alexander, K.S., and Dollimore, D. "Thermal Analysis of the Evaporation of Compounds Used in Aromatherapy, "podium presentation at the 28th Conference of the North American Thermal Analysis Society, Orlando, FL, September 16-19, 2000

  41. Menon, D., Dollimore, D., and Alexander, K. "A TG-DTA Study of Sublimation of Nicotinic Acid," podium presentation at the 28th Conference of the North American Thermal Analysis Society, Orlando, FL, September 16-19, 2000

  42. Burnham, L., Dollimore, D., and Alexander, K. "A Rising Temperature Kinetic Model to Describe Complex Reactor Kinetics of the Drug Procainamide HCl," podium presentation at the 28th Conference of the North American Thermal Analysis Society, Orlando, FL, September 16-19, 2000

  43. Vora, A., Alexander, K.S., and Dollimore, D. "Thermal Stability of Folic Acid and Associated Excipients," podium presentation at the 28th Conference of the North American Thermal Analysis Society, Orlando, FL, September 16-19, 2000

  44. Wright, S.F., Phang, P., Dollimore, D., Alexander, K.S. "The Use of Benzoic Acid as a Calibration Material in Thermal Analysis," podium presentation at the 28th Conference of the North American Thermal Analysis Society, Orlando, FL, September 16-19, 2000

  45. Khan, F., Alexander, K.S., and Dollimore, D. "A Thermal Analysis Study of the Dehydration of Epsom Salt," podium presentation at the 28th Conference of the North American Thermal Analysis Society, Orlando, FL, September 16-19, 2000

  46. Khan, N., Dollimore, D., and Alexander, K.S. "The Kinetics of Decomposition of Magnesium Carbonate Hydroxide Hydrate" podium presentation at the 28th Conference of the North American Thermal Analysis Society, Orlando, FL, September 16-19, 2000

  47. Chatterjee, A. Hazra, D. Dollimore, K.S. Alexander, a poster Number W4648 entitled, "Rapid Estimation of Vapor Pressure Curves by Thermogravimetry," presented at the AAPS Annual Meeting and Exposition in Denver, Colorado, October 21-25, 2001

  48. K.S. Alexander, "Drug Polymorphism" podium presentation to the Ohio Regional Thermal Analysis Symposium, University of Akron, Akron, OH, June 12, 2002

  49. A. T. Riga and K.S. Alexander,"Activity of Druga in Transdermal Patches by Dielectric Thjermal Analysis," presented at the 30th Annual Meeting of the North American Thermal Analysis Society, Pittsburgh, PA, September 23-25, 2002

  50. A. T. Riga B. Biddlecom, K.S. Alexander, "Thermal Properties and Drug Interactions of Excipients by DSC and TG presented at the 30th Annual Meeting of the North American Thermal Analysis Society, Pittsburgh, PA, September 23-25, 2002

  51. A. T. Riga, S. Roy, K.S. Alexander,"A Differential Scanning Calorimetry Standard Test Method Based on Statristical Experimental Design for Pharmaceutical Preformulation Research and Quality Control" presented at the 30th Annual Meeting of the North American Thermal Analysis Society, Pittsburgh, PA, September 23-25, 2002

  52. P. Chakravarty, K.S. Alexander, A. T. Riga "DSC Study of Low Temperature Properties of Vegetable Oils", podium presentation to the Ohio Regional Thermal Analysis Symposium, University of Akron, Akron, OH, June 12, 2003

  53. S. Majundar, K.S. Alexander, A.T. Riga, "Determination of the Glass Transition Temperature (Tg) for Various Grades of Microcrystalline Cellulose (MCC) and the Effect of Absorbed Moisture on this Parameter," presented at the 30th Annual Meeting of the North American Thermal Analysis Society, Pittsburgh, PA, September 23-25, 2002

  54. P. Mitra, K.S. Alexander, A.T. Riga, "Optimizing the Experimental Condit-ions and Determining the Bound Water Associated with Commercially Available Suspensions of Milk of Magnesia," presented at the 30th Annual Meeting of the North American Thermal Analysis Society, Pittsburgh, PA, September 23-25, 2002

  55. P. Nandi, K.S. Alexander, and A.T. Riga, "A Thermogravemetric Study of Peppermint Oil," presented at the 30th Annual Meeting of the North American Thermal Analysis Society, Pittsburgh, PA, September 23-25, 2002

  56. S. Sinha, K.S. Alexander, A.T. Riga, "Determination of the Kinetic Model of Decomposition for the Commercially Available Form of Sulfamenazine by Thermogravimetric Techniques," presented at the 30th Annual Meeting of the North American Thermal Analysis Society, Pittsburgh, PA, September 23-25, 2002

  57. K. Bhasi, , K.S. Alexander, A. T. Riga, "Evaluation of Bound Water in Flocculated Systems of Pumice Using DSC Experiments," presented at the 30th Annual Meeting of the North American Thermal Analysis Society, Pittsburgh, PA, September 23-25, 2002

  58. G. Pan, A. T. Riga, W. P. Pan, K. S. Alexander, "Dielectric Thermal Analysis and DSC of Liquid and Solid Pharmaceutical Excipients", presented at the 30th Annual Meeting of the North American Thermal Analysis Society, Pittsburgh, PA, September 23-25, 2002

  59. R. Vladapatla, N. Thyagarajapyram, K. S. Alexander, A. T. Riga, "Thermal Characterization of Amiodarone HCl and its Interactions With Excipients", presented at the 30th Annual Meeting of the North American Thermal Analysis Society, Pittsburgh, PA, September 23-25, 2002

  60. Kenneth S. Alexander "Thermal Analytical Techniques used in the Phrmaceutical Industry", presented at the International Conference on Pharmnaceutical Technology and Quality Control(VII PHARMATECH: IV ENECQ) Centro de Convencoes, Hotel Tropical Tambau, Joao Pessoa, Brazil, August 6th-9th 2003

  61. Kenneth S. Alexander, "Thermal Analytical Techniques used in the Pharmaceutical Industry", presented to the North American Thermal Analysis Society, Thermal Analysis Short Course, September 20th -21st 2003

  62. A. T. Riga, A. O’Conner, C. Scott, D. Nash and K.S. Alexander, "Thermal Analysis in University Research and Undergraduate Teaching Labs" presented at the 30th Annual Meeting of the North American Thermal Analysis Society, Williamsburgh, VA, October 4-6, 2004

  63. R. Szalkowski, A. T. Riga, A Somrack and K.S. Alexander, "Bio-Polymer Snake SkinFilms Characterized by Thermal Analytical Methods," presented at the 32nd Annual North American Thermal Analysis Society, Williamsburgh, VA, October 4-6, 2004 (CD)

  64. K. S. Alexander "Extemporaneous Formulation of Liquid Pediatric/ Geriatric Dosage Forms from Commercially Available Tablets and Capsules" presented to the Carrabean Pharmaceutical Association, Beleize City. Belieze August 18th, 2004

  65. Kenneth S. Alexander, "Thermal Analytical Techniques used in the Pharmaceutical Industry", presented to the North American Thermal Analysis Society, Thermal Analysis Short Course, October 2- 6, 2004

Posters

  1. Educational Enrichment Through Undergraduate Research: A Dual Purpose Pharmaceutics Experience, Poster Session presented to the Pharmaceutics Section, American Association of Colleges of Pharmacy Annual Meeting, June 28, 1982, Kansas City, Missouri

  2. Changing the Status Quo of Teaching: Adopting Systematic Instruction, Poster Session presented to the Pharmaceutics Section, American Association of Colleges of Pharmacy Annual Meeting, June 28, 1982, Kansas City, Missouri

  3. Degradation Studies with Aspirin, Poster Session presented at the Anachem Symposium by Ager, D., Alexander, K., Bhatti, A., Dollimore, D., Koogan, T., Mooseman, K. and Mahovic, October 13, 1983, Dearborn, Michigan

  4. Hyperalimentation Component Compatibility Prediction, Poster Session presented at the Joint Annual Ohio State Pharmaceutical Association and Midyear Ohio State Pharmacists Association Convention, October 20, 1984, Akron, Ohio

  5. Computer and Microcomputer Assisted Instruction in Pharmaceutical Calculations at The University of Toledo, Poster Session presented to the American Association of Colleges of Pharmacy, Annual Meeting, Toronto, Canada, July 1986

  6. Stability of Certified Dyes, Poster Session presented at the Undergraduate Research Seminar, West Virginia University, by M. Vuletich, N. Dmytryka, J. Vogel, M. Savage and K. Alexander, November 12, 1986, Morgantown, West Virginia

  7. An Investigation of Suspensions of China Clay Including Pharmaceutical Kaolin Preparations - Poster presented at the Annual Pharmaceutical Graduate Student Research Seminar by F.A. Patel and K. Alexander, The University of Michigan, June 25, 1987, Ann Arbor, Michigan

  8. J.K. Smith, R.T. Baumann, W.T. Gunning and K.S. Alexander poster presentation "Particulate Matter Content of D5/NS for Injection: Manufacturer Difference and Conformance with USP Limits" given at the Seventh Annual Ohio Conference on Clinical Pharmacy and Clinical Pharmacology, Sea Gate Center, Toledo, Ohio, September 11, 1987

  9. L. Annancy, J.K. Smith, W.T. Gunning and K.S. Alexander poster presentation "Intravenous Fluid Particulate Matter Content: Manufacturer Difference and Conformance with USP Limits" given at West Virginia University, Undergraduate Research Seminar, November 11-13, 1987

  10. Dani, K., Alexander, K.S., and Dollimore, D., "Finger Printing of Ascorbic Acid Pharmaceutical Formulations by Differential Thermal Analysis (DTA)," poster presented at the Twentieth Annual Pharmaceutical Graduate Student Research Meeting, The University of Missouri-Kansas City, Kansas City, Missouri, June 10, 1988

  11. Gupchup G.V., Alexander, K.S., Dollimore, D. and Wilburn, F.W., "A Behavioral Study of Aspirin in the Solid State Using Thermal Analytical Techniques," poster presentation at:
    1. Midwest Regional Meeting, The American Association of Pharmaceutical Scientists, The O'Hare Marriot, Chicago, Illinois, May 14, 1990
    2. 22nd Annual Pharmaceutics Graduate Research Meeting, Ohio State University, Columbus, Ohio, June 15-17, 1990.
  12. Tata, S.S., Alexander, K.S. and Dollimore, D., "Sedimentation of Concentrated Magnesium Hydroxide Suspensions," poster presentation at:
    1. Midwest Regional Meeting, The American Association of Pharmaceutical Scientists, The O'Hare Marriot, Chicago, Illinois, May 14, 1990
    2. 22nd Central Regional Meeting, American Chemical Society, Saginaw Valley State University, Saginaw, Michigan, June 6, 1990
    3. 22nd Annual Pharmaceutics Graduate Research Meeting, Ohio State University, Columbus, Ohio, June 15-17, 1990
  13. Haribhakti, R.P., Alexander, K.S. and Parker, G.A., "Formulation Development and Stability of Pediatric Acetazolamide Suspensions," poster presentation at:
    1. Midwest Regional Meeting, The American Association of Pharmaceutical Scientsts, The O'Hare Marriot, Chicago, Illinois, May 14, 1990
    2. 22nd Annual Pharmaceutics Graduate Research Meeting, Ohio State University, Columbus, Ohio, June 15-17, 1990
  14. Madhusudhan, P., Alexander K.S. and Parker, G., "Formulation Development and Stability of Pediatric/Geriatric Hydralazine Hydrochloride Syrup"
    1. Poster presentation, Midwest Regional Meeting, The American Association of Pharmaceutical Scientists, The O'Hare Marriott, Chicago, Illinois, May 6, 1991
    2. Poster Presentation, 50th Ann. Anachem Symposium, Botsford Inn, Farmington, Michigan, November 7, 1991
  15. Sujata, S., Alexander, K.S., Parker, G.A., Schwartz, E. and Pavlock, J., "Metal Binding Studies of Glycine and Dextrose in Hyperalimentation Solutions"
    1. Poster Presentation, Midwest Regional Meeting, The American Association of Pharmaceutical Scientists, The O'Hare Marriott, Chicago, Illinois, May 6, 1991
    2. Poster Presentation, 50th Ann. Anachem Symposium, Botsford Inn, Farmington, Michigan, November 7, 1991
  16. Swaminathan, S., Alexander, K.S., Parker, G.A., Schwartz, E. and Pavlov, J. "The Determination of Stability Constants for the Complexation of Dextrose and Glycine in Intravenous Fluids with Transition Metals"
    1. Poster Presentation, 23rd Annual Pharmaceutics Graduate Student Research Meeting, University of Wisconsin, Madison, Wisconsin, June 13-15, 1991
  17. Murthy, A.S., Alexander, K.S. and Dollimore, D., "Investigation of Sedimentation Parameters of Concentrated aluminum Hydroxide Slurries." presented at the, Midwest Regional Meeting, American Association of Pharmaceutical Scientists, O'Hare Marriott, Chicago, Illinois, May 6, 1991

  18. Alexander, K.S., Dollimore, D. and Gupchup, G.V., "The Thermal Degradation Process in Aspirin" Presented at the 23rd Central Regional Meeting and 24th Great Lakes Regional Meeting of the American Chemical Society, University Place Conference Center, Indiana University, Purdue University at Indianapolis, Indiana, May 29-31, 1991

  19. Haribhakti, R., Madhusudan, P.and Alexander, K.S., "Anticipating Unusual Uses for Commercially Formulated Tablets and Capsules" Presented at the Southeastern Regional Meeting, American Association of Pharmaceutical Scientists, Blockade Runner Resort, Wilmington, NC, April 9, 1992

  20. Dawar, N., Alexander, K.S. and Parker, G., "Formulation ad Stability of Allopurinol Suspension Compounded from Tablets" presented at the Midwest Regional Meeting, American Association of Pharmaceutical Scientists, O'Hare Marriott, Chicago, Illinois, May 4, 1992

  21. Konar, N., Alexander, K.S. and Dollimore, D., "The Flocculating Action of Cholesterol on Calcium Oxalate" Presented at the Midwest Regional Meeting, American Association of Pharmaceutical Scientists, O'Hare Marriott, Chicago, Illinois, May 4, 1992

  22. Gangwal, D., Alexander, K.S. and Dollimore, D., "Settling Behavior of Concentrated Suspensions of Aluminum Hydroxide Made from Gel in the ‘Never-Dried’ State and From Dry Aluminum Hydroxide Powder" Poster presentation, Midwest Regional Meeting, American Association of Pharmaceutical Scientists, O'Hare Marriott, Chicago, Illinois, May 4, 1992

  23. Patel, D., Alexander, K.S. and Dollimore, D., "The Use of Thermogravimetry to Determine Cholesterol, Calcium Carbonate and Calcium Oxalate in Gallstones" presented at the Midwest Regional Meeting, American Association of Pharmaceutical Scientists, O'Hare Marriott, Chicago, Illinois, May 4, 1992

  24. Noorul-Huda, A.F., Alexander, K.S., Bensch, K. and Dollimore, D., "Investigation and Characterization of a Model Carbon System in Concentrated Slurries" presented at the Midwest Regional Meeting, American Association of Pharmaceutical Scientists, O'Hare Marriott, Chicago, Illinois, May 4, 1992

  25. Chirarutsami, W., Kusolmanomai, N., Alexander, K.S. and Dollimore, D., "An Investigation of the Dehydration of Magnesium Hydroxide Paste" Presented at the Midwest Regional Meeting, American Association of Pharmaceutical Scientists, O'Hare Marriott, Chicago, Illinois, May 4, 1992

  26. Smith, L. Wunderly, D., Pryka, R. and Alexander, K.S., "Stability of Sodium Citrate Irrigation", presented at the American Society of Hospital Pharmacists Mid-Year Clinical Meeting, Orlando, Florida, Florida, December 6-10, 1992

  27. Patel, D., Alexander, K.S., and Dollimore, D., "Characterization of the Tablet Lubricant Magnesium Stearate Using Qualitative Techniques", presented at the Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 17, 1993

  28. Vangala, S., Alexander, K.S., Parker, G.A., "Formulation Development and Chemical Stability of Extemporaneously Prepared Spironolactone Suspension" presented at the Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 17, 1993

  29. Rayathatha, S. Dollimore, D. and Alexander, K.S., "The Shelf Life Determination of an Extemporaneously Formulated Hydralazine HCl Syrup Using Simple Syrup", presented at the Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 17, 1993

  30. Roy, D., Alexander, K.S., Parker, G.A., "The Determination of the Complexation of Dextrose and the Amino Acid Serine with Transition Metals in Intravenous Fluids" presented at the Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 17, 1993

  31. Okatchareon, S., Alexander, K.S. and Dollimore, D., "The Investigations of Concentrated Suspensions of Aluminum Hydroxide, Magnesium Hydroxide and Calcium Carbonate", presented at the Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 17, 1993

  32. Kusolmanomai, N., Alexander, K.S. and Dollimore, D., "The Behavior of the Never Dried Magnesium Hydroxide Suspension Compared with the Addition of Polymer Flocculant". Presented at the Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 17, 1993

  33. Kothapoli, M., Alexander, K.S., Parker, G.A., "Stability of Extemporaneously Compounded Levothyroxine Sodium Syrup from Tablets", presented at the Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 17, 1993

  34. Agrawal, M., Alexander, K.S. and Chrysochoos, J., "Photodegradation Studies of Erythrosin (Red #3) in Aqueous Solutions", presented at the Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 17, 1993

  35. Rayathatha, S., Dollimore, D. and Alexander, K.S., "Use of Temperature Jump and Isothermal Methods to Determine the Shelf Life of Hydralazine HCl Syrup", presented at the 25th Annual Pharmaceutics Graduate Research Meeting, Purdue University, West Lafayette, Indiana, June 10-12, 1993

  36. Roy, D., Alexander, K.S., Parker, G.A., "The Determination of Stability Constants for the Complexation of Serine and Dextrose With Transition Metals in Intravenous Fluids" presented at the 25th Annual Pharmaceutics Graduate Research Meeting, Purdue University, West Lafayette, Indiana, June 10-12, 1993

  37. Okatchareon, S., Alexander, K.S. and Dollimore, D., "The Hindered Settling Behavior of Calcium Carbonate and Magnesium Hydroxide and the Synthesis of Aluminum Hydroxide inb the Never Dried State", presented at the 25th Annual Pharmaceutics Graduate Research Meeting, Purdue University, West Lafayette, Indiana, June 10-12, 1993

  38. Agrawal, M., Alexander, K.S. and Chrysochoos, J., "Photostability of Aqueous Solutions of Erythrosin (Red #3)" presented at the 25th Annual Pharm. Graduate Research Meeting, Purdue University, West Lafayette, Indiana, June 10-12, 1993

  39. Nair, K., Alexander, K.S., and Dollimore, D., presented:
    1. "A Study of the Thermal Decomposition of Dolomite by the Presence of Excipients Particle Size", Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, IL, May 23, 1994
    2. "A Study of the Thermal Decomposition of Dolomite as Influenced by the Presence of Excipients and Particle Size", 26th Central Regional Meeting and 27th Great Lakes Regional Meeting of the American Chemical Society, University Conference Center, University of Michigan, Ann Arbor, Michigan, June1-3, 1994
    3. "An Assessment of the Solid State Reactivity of Dolomite as Influenced by Particle Size and the Presence or Excipients Using Thermal Analysis and Associated Techniques" Annual Pharmaceutics Graduate Research Meeting, University of Maryland, Baltimore, Maryland, June 3-5, 1994
  40. Heda, P., Alexander, K.S. and Dollimore, D. presented:
    1. "Stability Studies for Sodium Bicarbonate in Dental Formulations", Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 23, 1994
    2. "An Assessment of the Solid State Reactivity of Sodium Bicarbonate as a Dentifrice by Thermal Analysis", 26th Central Regional Meeting and 27th Great Lakes Regional Meeting of the American Chemical Society, University Conference Center, University of Michigan, Ann Arbor, Michigan, June1-3, 1994
    3. "An Assessment of the Solid State Reactivity of Sodium Bicarbonate as a Dentifrice Using Thermal Analysis", Annual Pharmaceutics Graduate Research Meeting, University of Maryland, Baltimore, MD, June 3-5, 1994
  41. Chakraborty, A., Alexander, K.S. and Dollimore, D. presented:
    1. "Solubility Studies of Mono Substituted Benzoic Acids". Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 23, 1994
    2. "Solubility and Thermodynamic Parameters of Mono Substituted Benzoic Acids", 26th Central Regional Meeting and 27th Great Lakes Regional Meeting of the American Chemical Society, University Conference Center, University of Michigan, Ann Arbor, Michigan, June1-3, 1994
    3. "Application of Extended Hildebrand Approach in Predicting Solubility of Mono Substituted Benzoic Acids in a Homologous Series of Pure Solvents". Annual Pharmaceutics Graduate Research Meeting, University of Maryland, Baltimore, Maryland, June 3-5, 1994
  42. Tong, P., Alexander, K.S., and Dollimore, D., poster presented:
    1. "A Study on the Effect of Cholesterol as a Flocculant on Gallstone-Related Calcium Salts by Means of Hindered Settling Techniques", Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 22, 1995
    2. "A Study of Hindered Settling Phenomena on Selected Calcium Oxysalts", The 27th Annual Pharmaceutics Graduate Research Meeting, University of Michigan, Baltimore, Ann Arbor, Michigan, June 22-24, 1995
  43. Ramachandruni, H., Alexander, K.S. and Dollimore, D. "Formulation of a Liquid Oral Dosage Form of Atenolol", poster presented at the Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 22, 1995

  44. Tahboub, I., Alexander, K.S., and Dollimore, D., poster presented:
    1. "The Behavior of Concentrated Suspensions of Carbon", Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 22, 1995
    2. "Investigation of a Carbon Black Model in Aqueous Suspension With Respect to Changes in Reactivity Parameters", The 27th Annual Pharmaceutics Graduate Research Meeting, University of Michigan, Ann Arbor, Michigan, June 22-24, 1995
  45. Lerdkanchanaporn, S., Alexander, K.S. and Dollimore, D. poster presented:
    1. "A Thermal Analysis Study of Ascorbic Acid and its Excipients in Pharmaceutical Formulations", Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 22, 1994
    2. "An Analytical Thermal Method to Study the Stability of Ascorbic Acid and Excipients Used in Pharmaceutical; Formulations", The 27th Annual Pharmaceutics Graduate Research Meeting, University of Michigan, Ann Arbor, Michigan, June 22-24, 1995
  46. Chaudhary, V., Alexander, K.S., and Dollimore, D., poster presented:
    1. "Characterization of Human Hair and the Analysis of Afro-American Hair Straightening Formulations in the Market", Midwest Regional Meeting, American Assoc. of Pharmaceutical Scientists, Chicago, IL, May 22, 1995
    2. "Statistical Analysis of Human Hair and the Development of Afro-American Hair Straightening Formulations", The 27th Annual Pharmaceutics Graduate Research Meeting, University of Michigan, Ann Arbor, Michigan, June 22-24, 1995
  47. Pendse, A., Alexander, K.S. and Dollimore, D. poster presented:
    1. "Interpretation of Hindered Settling Behavior of Magnesium Carbonate Suspensions", Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 22, 1995
    2. "The Effect of Physical Changes of the Reacting Environment on the Size and Hindered Settling Behaviorof Magnesium Carbonate Suspensions", The 27th Annual Pharmaceutics Graduate Research Meeting, University of Michigan, Ann Arbor, Michigan, June 22-24, 1995
  48. Motwani, Monica, Alexander, K.S., and Dollimore, D., "A Thermograimetric Study of a Cosmetic Cream", poster presented at the Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, IL, May 20, 1996

  49. Sun, Yichum, Alexander, K.S., and Dollimore, D., "The Measurement of the Activation Energy of Evaporation for Benzaldehyde", poster presented at the Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 20, 1996

  50. Basu, Aniraban, Pendse, A., Alexander, K.S. and Dollimore, D. poster presented:
    1. "Interpretation of Hindered Settling Behavior of Never Dried Magnesium Carbonate Suspensions", Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 20, 1996
    2. "Interpretation of Hindered Settling Behavior of Never Dried Magnesium Carbonate Suspensions", The 28th Annual Pharmaceutics Graduate Research Meeting, University of Minnesota, Minneapolis, Minnesota, June 28-30, 1996
  51. Arikapudi, Lalitha, Alexander, K.S. and Dollimore, D. "Investigation of the Thermal Degradation of A Beta-Adrenergic Blocking Agent", poster presented at the Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 20, 1996

  52. Aggrawal, Poonam, Alexander, K.S., and Dollimore, D., "The Use of a Thermogravimetry Unit to Follow the Rate of Evaporation of an Ingredient Used in Perfumes", poster presented at the Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 20, 1996

  53. Bahnu, Kalvokata., Sun, Yichun, Alexander, K.S. and Dollimore, D. "The Measurement of the Activation Energy of Evaporation for Benzaldehyde", poster presented at The 28th Annual Pharmaceutics Graduate Research Meeting, University of Minnesota, Minneapolis, Minnesota, June 28-30, 1996

  54. Yelamanchi, Kranthi, Motwani, Monica, Alexander, K.S. and Dollimore, D. "A Thermograimetric Study of a Cosmetic Cream", poster presented at The 28th Annual Pharmaceutics Graduate Research Meeting, University of Minnesota, Minneapolis, Minnesota, June 28-30, 1996

  55. Basu, A., Alexander, K.S. and Dollimore, D., "Predicting the Hindered Settling Behavior of Concentrated Suspensions", poster presented at the Midwest Regional Meeting, American Assoc. of Pharmaceutical Scientists, Chicago, IL May 19, 1997

  56. Yelamanchi, K., Alexander, K.S. and Dollimore, D., "Ointment Base Compositional Influence on the In Vitro Diffusion of Methyl Salicylate and the Effect of the Diffusional Cell on the Amount of Drug Released", poster presented at the Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 19, 1997

  57. Kalvakota, B., Alexander, K.S. and Dollimore, D., "Solid State Stability of Aspirin in the Presence of Excipients Using DTA-TA, HPLC and FTIR", poster presented at the Midwest Regional Meeting, American Association of Pharmaceutical Scientists, Chicago, Illinois, May 19, 1997.

  58. Sarver, J.G., Peng, N., Lerdkanchanaporn, S., Oravez-Wilson, K.I., Alexander, K.S. and Erhardt, P.W., "Analysis of Extemporaneous Alprostadil Formulations" poster presented at the 26th National Medicinal Chemistry Symposium, Omni Richmond Hotel, Richmond, VA, June 14-18, 1998.

  59. Burnham, L., Dollimore, D. and Alexander, K.S., "A Rising Temperature Kinetic Model to Describe Complex Reaction Kinetics of A Drug: Procainamide Hydrochloride. Poster presented at the 26th Annual N.A.T.A.S. Meeting, Cleveland, OH, September 13-15, 1998.

  60. Anasuya Hazra, Alexander, K.S., Pauline Phang, and Dollimore, D., "Determination of Kinetic Parameters of Evaporation of Some Essential Oils and Their Components Using Thermogravimetric Analysis," a poster presented at the 33rd Great Lakes/Central Regional Meeting, American Chemical Society, Grand Rapids, Michigan, June 11, 2001

  61. F. Khan, A. Riga, P. Phang, and K. Alexander, "Thermal Analysis Study of Magnesium Gluconate," poster presented at the 33rd Great Lakes/Central Regional Meeting, American Chemical Society, Grand Rapids, Michigan, June 11, 2001

  62. S. Roy, A.T. Riga, K.S. Alexander, and P. Phang, "An Evaluation of Parameters Affecting Preformulation Studies of Pharmaceuticals by DSC: A Statistical Approach," poster presented at the 33rd Great Lakes/Central Regional Meeting, American Chemical Society, Grand Rapids, Michigan, June 11, 2001

  63. D. Menon, M. El-Reis, P. Phang, and K.S. Alexander, "A Thermal Analysis Study of the Decomposition of Hydrochlorothiazide," poster presented at the 33rd Great Lakes/Central Regional Meeting, American Chemical Society, Grand Rapids, Michigan, June 11, 2001

  64. A. Vora, K. Alexander, P. Phang, and D. Dollimore, "A Thermal Analytical Evaluation of Folic Acid: Mixtures versus Commercial Product," poster presented at the 33rd Great Lakes/Central Regional Meeting, American Chemical Society, Grand Rapids, Michigan, June 11, 2001

  65. S. Hassannejad Tabasi, D. Dollimore, K. Alexander, and P. Phang, "Estimation of Floc Size for Suspensions of Calcium Oxalate Using Cholesterol and the Shape Factor Parameter," poster presented at the 33rd Great Lakes/Central Regional Meeting, American Chemical Society, Grand Rapids, Michigan, June 11, 2001

  66. Nitin, K., Nagarajan, T. and Alexander, K.S., "Formulation Development and Stability Testing of an Extemporaneous Suspension from Dapsone Tablets" a poster presented at the 33rd Pharmaceutics Graduate Student Research Meeting, The University of Wisconsin, Madison, WI, June 14-16, 2001

  67. Roy, S., Riga, A.T., and Alexander, K.S., "A Statistical Approach for the Development of a Standard Protocol for Differential Scanning Calorimetry (DSC) Used in Preformulation Studies of Pharmaceuticals" poster presented at the 33rd Great Lakes/Central Regional Meeting, American Chemical Society, Grand Rapids, Michigan, June 11, 2001

  68. Vora, P.V., Alexander, K.S., and Dollimore, D., "Characterization of the Thermal Behavior of Vitamins: Nicotinic Acid and Nicotinamide Using Thermogravimetry" poster presented at the 33rd Great Lakes/Central Regional Meeting, American Chemical Society, Grand Rapids, Michigan, June 11, 2001

  69. S. Kaushik, K.S. Alexander, and A.T. Riga, "Analysis and Stability Testing of an Extemporaneous Solution Prepared from Commercially Available Mexiletine Hydrochloride Capsules Using High Performance Liquid Chromatography," poster presented at the 34th Pharmaceutics Graduate Student Research Meeting, University of Nebraska Medical Center, Omaha, Nebraska, June 13-15, 2002.

  70. S. Majundar, K.S. Alexander, A.T. Riga, "Determination of the Glass Transition Temperature (Tg) for Various Grades of Microcrystalline Cellulose (MCC) and the Effect of Absorbed Moisture on this Parameter," poster presented at the 34th Pharmaceutics Graduate Student Research Meeting, University of Nebraska Medical Center, Omaha, Nebraska, June 13-15, 2002.

  71. P. Mitra, K.S. Alexander, A.T. Riga, "An Investigation of the Decomposition Kinetics and Types of Water Associated with Magnesium Hydroxide in Suspension," poster presented at the 34th Pharmaceutics Graduate Student Research Meeting, University of Nebraska Medical Center, Omaha, Nebraska, June 13-15, 2002.

  72. P. Nandi, K.S. Alexander, and A.T. Riga, "A Statistical Approach for the Evaluation of Thermogravemetric Parameters Affecting Studies of Volatile Oils," poster presented at the 34th Pharmaceutics Graduate Student Research Meeting, University of Nebraska Medical Center, Omaha, Nebraska, June 13-15, 2002.

  73. S. Sinha, K.S. Alexander, A.T. Riga, "Determination of the Kinetic Model of Decomposition and Shelf-Life for the Commercially Available Form of Sulfamenazine by Thermogravimetric Techniques," poster presented at the 34th Pharmaceutics Graduate Student Research Meeting, University of Nebraska Medical Center, Omaha, Nebraska, June 13-15, 2002.

  74. R. Thirumangalathu, P. Nandi, K.S. Alexander, J.P. Byers, "Preparation and Evaluation of Phenylpropanolamine Hydrochloride Microspheres," poster presented at the 34th Pharmaceutics Graduate Student Research Meeting, University of Nebraska Medical Center, Omaha, Nebraska, June 13-15, 2002.

  75. S. Majundar, K.S. Alexander, A.T. Riga, "Clustered and Unbound Water in the Excipient Microcrystaline Cellulose by DSC and TGA", a poster presented at the North Coast Thermal Analysis Society, Glidden Pain Division of ICI, Strongsville, OH March 13, 2003

  76. P. Chakravarty, K.S. Alexander, A. T. Riga, "DSC Study of Low Temperature Properties of Vegetable Oils", poster presentation at the:
    1. North Coast Thermal Analysis Society, Glidden Pain Division of ICI, Strongsville, OH March 13, 2003
    2. 35th Annual Pharmaceutics Graduate Research Meeting, Chicago, IL, June 12-14th , 2003
  77. L. Oberoi, K.S. Alexander, A. T. Riga, "Application of DSC to Study Eutectics and Their Use in Pharmaceuticals", poster presentation at the:
    1. North Coast Thermal Analysis Society, Glidden Pain Division of ICI, Strongsville, OH, March 13, 2003
    2. 35th Annual Pharmaceutics Graduate Research Meeting, Chicago, IL, June 12-14th , 2003
  78. P. Nandi, K.S. Alexander, A.T. Riga, "Thermal Characterization and Kinetics of Essential Oils and Their Major Constituents used in Aroma Therapy", a poster presented at the North Coast Thermal Analysis Society, Glidden Pain Division of ICI, Strongsville, OH March 13, 2003

  79. S. Sinha, K. S. Alexander, A. T. Riga, "Evaluation of the Amorphous Form of Sulfapyridine: The Effect of Moisture and Excipients", a poster presented at the North Coast Thermal Analysis Society, Glidden Pain Division of ICI, Strongsville, OH March 13, 2003

  80. R. Vadlapatla, K. S. Alexander, A. T. Riga, "Solid State Characterization of Hydrates of Aminophylline and Their Interaction with Excipients", a poster presented at the North Coast Thermal Analysis Society, Glidden Pain Division of ICI, Strongsville, OH March 13, 2003

  81. B. Dattachowdhury, K. S. Alexander, A. T. Riga, "Thermal Characterization of Polylactic Acid", a poster presented at the North Coast Thermal Analysis Society, Glidden Pain Division of ICI, Strongsville, OH March 13, 2003

  82. M. A. Williams, K. S. Alexander, A. T. Riga, "A Study od the Value of Thermal Mechanical Analysis in Assessing Disintegrants in Pharmaceutical Tablets", a poster presented 35th Annual Pharmaceutics Graduate Research Meeting, Chicago, IL, June 12-14th , 2003

  83. B. Dattachowdhury, K. S. Alexander, A. T. Riga, "Characterization of Polylactic Acid", a poster presented at the 35th Annual Pharmaceutics Graduate Research Meeting, Chicago, IL, June 12-14th , 2003

  84. R. Vadlapatla, K. S. Alexander, A. T. Riga, "Solid State Characterization of Anhydrous and Hydrous Forms of Aminophylline and Their Invivo Drug Release Patterns," a poster presented at the 35th Annual Pharmaceutics Graduate Research Meeting, Chicago, IL, June 12-14th , 2003

  85. Michael Tetelman, Alan T. Riga, Marcia A. Williams and Kenneth S. Alexander, a poster entitled, "Characterization of Sustained Release Ritalin, Methyphenidate HCl, by Isothermal Mechanical Analysis"," presented at the 31st North American Thermal Analysis Society, Sept. 22-24, 2003, Albuquerque, NM

  86. Williams, M. A, Alexander,K. S. and Riga, A.T, a poster entitled "A Study of the Value of Thermal Mechanical Analysis in Assessing Disintegrants in Pharmaceutical Tabletting", presented at the 31st North American Thermal Analysis Society, Sept. 22-24, 2003, Albuquerque, NM

  87. Desai, J., Alexander, K. S. and Riga, A.T., a poster entitled "Influence of Experimental Variables on Differential Scanning Calorimetry Studies of Indomethocin and Antipyrine," presented at the 2nd Annual Regional Recognition and Poster Competition, North Coast Thermal Analysis Society, ICI Glidden, Strongsville, OH March 18th 2004

  88. Pinaki Basu, Kenneth S. Alexander, Alan T. Riga,a poster entitled "A Statistical Experimental Design for the Evaluation of Parameters Affecting Preformulation Studies of Drugs by Differential Scanning Calorimetry," presented at the 2nd Annual Regional Recognition and Poster Competition, North Coast Thermal Analysis Society, ICI Glidden, Strongsville, OH March 18th 2004

  89. Jayeeta Sen, Kenneth S. Alexander and Alan T. Riga, poster entitled "Analysis of the Mechanical Properties of Three Grades of Poly Vinyl Pyrrolidone Varied by Their Difference in Molecular Weights Using Isothermal and Scanning Thermal Mechanical Analysis", presented at the36th Central Regional Meeting, American Chemical Society, Indiana University Purdue University, Indianapolis, IN, June 2nd-4th, 2004

  90. Williams, M. A., Alexander, K. S., Riga, A. T., poster entitled "The Thermal Mechanical Analyzer As A Preformulation Tool in Assessing Disintegrants", presented at the 36th Annual Pharmaceutics Graduate Student Research Meeting, The University of Iowa, Iowa City, Iowa, June 10th-12th, 2004

  91. I. Rao, K. S. Alexander, A. T. Riga, poster entitled "A Statistical Study of the Different Parameters Affecting Heat of Vaporization of Water of an Aqueous Blend of Pharmaceuticals by Utilizing Differential Scanning Calorimetry" presented at the 36th Annual Pharmaceutics Graduate Student Research Meeting, The University of Iowa, Iowa City, Iowa, June 10th-12th , 2004

  92. A. Jones, K. S. Alexander, A. T. Riga, poster entitled "A Study of Clonidine HCl by DSC and TGA to Determine the Decomposition Kinetics and Oxidative Stability", presented at the 36th Annual Pharmaceutics Graduate Student Research Meeting, The University of Iowa, Iowa City, Iowa, June 10th-12th , 2004

  93. Jinal N. Desai, Kenneth S. Alexander, Alan T. Riga, poster entitled "Differential Scanning Calorimetry Studies of Indomethocin and Antipyrine" presented at the 36th Annual Pharmaceutics Graduate Student Research Meeting, The University of Iowa, Iowa City, Iowa, June 10th-12th , 2004

  94. Pinaki Basu, Kenneth S. Alexander, Alan T. Riga, poster entitled "A Statistical Approach in the Estimation and Evaluation of Parameters Affecting Preformulation Studies of Drugs by DSC" presented at the 36th Annual Pharmaceutics Graduate Student Research Meeting, The University of Iowa, Iowa City, Iowa, June 10th-12th , 2004

  95. Sen, Jayeeta, Alexander, K. S., Riga, A. T., poster entitled "Thermal Mechanical Characterization of Three Different Grades of Polyvinyl Pyrrolidone by Using the Isothermal and Scanning Mode of TMA" presented at the 36th Annual Pharmaceutics Graduate Student Research Meeting, The University of Iowa, Iowa City, Iowa, June 10th-12th, 2004

  96. Sen, Jayeeta, Alexander, K. S. and Riga, A.T., a poster entitled "Isothermal and Scanning Thermal Mechanical Analysis of Three Grades of Poly Vinyl Pyrrolidone Having different Molecular Weights", presented at the 2nd Annual Regional Recognition and Poster Competition, North Coast Thermal Analysis Society, ICI Glidden, Strongsville, OH March 18th 2004

  97. Rao, I., Alexander, K. S. and Riga, A.T., a poster entitled "A Stastistical Approach for the Evaluation of the Parameters Affecting Evaporation Studies for Aqueous Blends by Differentiasl Scanning Calorimetry," presented at the 2nd Annual Regional Recognition and Poster Competition, North Coast Thermal Analysis Society, ICI Glidden, Strongsville, OH March 18th 2004

  98. Williams, M. A., Alexander, K. S., Riga, A. T., a poster entitled "A Comparison of the Disintegrant Properties of Three Starches and a Super Disintegrant Using Thermal Mechanical Analysis," presented at the 2nd Annual Regional Recognition and Poster Competition, North Coast Thermal Analysis Society, ICI Glidden, Strongsville, OH March 18th 2004

  99. Bhaswati Dattachowdhury, Kenneth S. Alexander, Alan T. Riga, and Koustuv Chatterjee, a poster entitled "Application of Theoretical Models in the Crystallization Kinetics of Sulfapyridine from the Amourphous State" presented at the 2nd Annual Regional Recognition and Poster Competition, North Coast Thermal Analysis Society, ICI Glidden, Strongsville, OH, March 18th 2004

  100. Paroma Chakravarty, Kenneth S. Alexander, Alan T. Riga. A poster entitled "Evaluation of Tolbutamide-PEG 8000 solid Dispersion: Effect of Surfactants", presented at the 2nd Annual Regional Recognition and Poster Competition, North Coast Thermal Analysis Society, ICI Glidden, Strongsville, OH March 18th 2004

  101. Lalit M. Oberoi, Kenneth S. Alexander and Alan T. Riga, a poster entitled, Solubility Enhancement of Ibuprofen by Using Nicotinamide as a Hydrotropic Agent- Application of DSC and Spectroscopy in Assessment of the Type of Interaction", presented at the 2nd Annual Regional Recognition and Poster Competition, North Coast Thermal Analysis Society, ICI Glidden, Strongsville, OH March 18th 2004

  102. Jinal Desai, Lalit M. Oberoi, Kenneth S. Alexander and Alan T. Riga, poster entitled "Solubility Enahancement of Ibuprofen Using Nicotinamide as a Hydrotropic Agent- Study of the Interaction by Thermal Spectroscopic and Microscopic Techniques", presented at the 36th Central Regional Meeting, American Chemical Society, Indiana University Purdue University, Indianapolis, IN, June 2nd-4th, 2004

  103. Paroma Chakravarty, Kenneth S. Alexander, Alan T. Riga, Koustuv Chatterjee and Pinaki Basu, poster entitled "Effect of Surfactantson Drug Dissolution of Tolbutamide: Use in Solid Dispersions and Dissolution Media", presented at the 36th Central Regional Meeting, American Chemical Society, Indiana University Purdue University, Indianapolis, IN, June 2nd-4th, 2004

  104. Bhawati DattaChowdhury and Kenneth S. Alexander, poster entitles "Application of Theoretical Models in the Crystallization Kinetics of Nifidepine from the Amourphous State", presented at the 36th Central Regional Meeting, American Chemical Society, Indiana University Purdue University, Indianapolis, IN, June 2nd-4th, 2004

  105. Amanda Jones, Kenneth S. Alexander and Alan T. Riga, poster entitled "Thermal Analysis of Clonidine HCl by DSC and TGA to Determine the Oxidative Stability and Decomposition Kinetics", presented at the 36th Central Regional Meeting, American Chemical Society, Indiana University Purdue University, Indianapolis, IN, June 2nd-4th, 2004

  106. Jinal N. Desai, Kenneth S. Alexander and Alan T. Riga, poster entitled "Characterization of Indomethocin and Antipyrine Using Differential scanning Calorimetry", presented at the36th Central Regional Meeting, American Chemical Society, Indiana University Purdue University, Indianapolis, IN, June 2nd-4th, 2004

  107. Pinaki Basu, Kenneth S. Alexander and Alan T. Riga, poster entitled "A Statistical Approach in the Estimation and Evaluation of Parameters Affecting Preformulation Studies of Drugs by Thermal Analysis", presented at the36th Central Regional Meeting, American Chemical Society, Indiana University Purdue University, Indianapolis, IN, June 2nd-4th, 2004

  108. Indranil R. Rao, Kenneth S. Alexander and Alan T. Riga, poster entitled "Vaporization of Water in the Presence of Glass Beads While Changing Various Parameters Utilizing Differential Scanning Calorimetry", presented at the36th Central Regional Meeting, American Chemical Society, Indiana University Purdue University, Indianapolis, IN, June 2nd-4th, 2004

  109. Marcia A. Williams, Kenneth S. Alexander and Alan T. Riga, poster entitled "A Study of the Relationship Between Solvent Expansion of Tablets as Measured by the Thermal Mechanical Analyzer and Their Disintegration Time", presented at the36th Central Regional Meeting, American Chemical Society, Indiana University Purdue University, Indianapolis, IN, June 2nd-4th, 2004

  110. P. Basu, K.S. Alexander, A.T. Riga, "A Statistical Model for the Optimization of DSC Performance in the evaluation of Drugs for Preformulation Studies," poster presented at the 32nd Annual North American Thermal Analysis Society, Williamsburgh, VA, October 4-6, 2004.(CD).

  111. J. Desai, K.S. Alexander, A.T. Riga, "Thermal Mechanical Characterization of Three Different Grades Of Poly Vinyl Pyrrolidon Using The Isothermal and Scanning Mode of TMA," poster presented at the 32nd Annual North American Thermal Analysis Society, Williamsburgh, VA, October 4-6, 2004.(CD)

  112. A. Jones, K.S. Alexander, A.T. Riga, "Thermal Thermal Oxidative Stability and Decomposition Kinetics of Clonidine HCl by DSC and TGA," poster presented at the 32nd Annual North American Thermal Analysis Society, Williamsburgh, VA, October 4-6, 2004.(CD)

  113. M. Williams, K.S. Alexander, A.T. Riga, "The Use of the Thermal Mechanical Analyzer in Comparing the Solvent Expansion of Tablets Formulated with Different Disintegrating Agents," poster presented at the 32nd Annual North American Thermal Analysis Society, Williamsburgh, VA, October 4-6, 2004.(CD)

  114. I. Rao, K, Alexander, A. T. Riga, "A Statistical Approach for the Evaluation of Parameters Affecting Vaporization of an Aqueous Blend by Differential Scanning Calorimetry" poster presented at the 32nd Annual Meeting of the North American Thermal Analysis Society, Williamsburgh, VA, October 4-6, 2004 (CD).

  115. JDesai, K. S. Alexander, A. T. Riga, "Preparation of Dimenhydrinate Controlled Release Formulations Using Wet Granulation and Solid Dispersion Techniques", a poster presented at the North Coast Thermal Analysis Society, Glidden Pain Division of ICI, Strongsville, OH March 17, 2005

  116. A. Jones, K. S. Alexander, A. T. Riga, "Pharmaceutical Eutectics: Evaluation andRelevance in PreformulationStudies Using Thermal Analytical Techniques", a poster presented at the North Coast Thermal Analysis Society, Glidden Pain Division of ICI, Strongsville, OH March 17, 2005

  117. I. Rao, K. S. Alexander, A. T. Riga, "A Vaporization Study of Vegetable Oils and Their Constituents: Construction of Vapor Pressure Curves and Kinetics of Degradation by Thermogravimetry", a poster presented at the North Coast Thermal Analysis Society, Glidden Pain Division of ICI, Strongsville, OH March 17, 2005

  118. J. Sen, K. S. Alexander, A. T. Riga, "Synergistic Effects of PVP and PEG on the Thermal Behavior and Release Profiles of Naproxen;", a poster presented at the North Coast Thermal Analysis Society, Glidden Pain Division of ICI, Strongsville, OH March 17, 2005

  119. P. Ma, K. S. Alexander, A. T. Riga, "Thermal Properties of Seven Whole Grain Rice Varieties", a poster presented at the North Coast Thermal Analysis Society, Glidden Pain Division of ICI, Strongsville, OH March 17, 2005

  120. J. Desai, K. S. Alexander, A. T. Riga, "Preparation of Dimenhydrinate Controlled Release Formulations Using Wet Granulation and Solid Dispersion Techniques", a podium presentation at the 37th Annual Pharmaceutics Graduate Research Meeting, University of Kansas,Lawrence, KS, June 9-11th, 2005

  121. P. Ma, K. S. Alexander, A. T. Riga, "Thermal Properties of Seven Whole Grain Rice Varieties" a poster presented at the 37th Annual Pharmaceutics Graduate Research Meeting, University of Kansas,Lawrence Kansas, June 9-11th, 2005

Publications

  • Smith, J.K., Baumann, R.R., Gunning, W.T., Annancy, L. and Alexander, K.S., "Particulate Matter Content of D5/NS for Injection: Manufacturer Difference and Conformance with U.S.P. Limits," J. Parenteral Science & Technology, 42(6), 180-6 (1988)
  • Alexander, K.S., Azizi, J., Dollimore, D. and Patel, F.A., "An Interpretation of the Sedimentation Behavior of Pharmaceutical Kaolin and Other Kaolin Preparations in Aqueous Environments," Proceedings of the 8th Pharmaceutical Technology Conference, pp. 203-226, Monte Carlo, Monaco, 1989
  • Alexander, K.S., Azizi, J., Dollimore, D. and Patel, F.A., "An Interpretation of the Sedimentation Behavior of Pharmaceutical Kaolin and Other Kaolin Preparations in Aqueous Environments," J. Drug Develop. & Ind. Pharm., 15(14-16), 2559 (1989)
  • Lee, C.Y., Mauro, V.F. and Alexander, K.S., "Intravenous Compatibility of Streptokinase and Tissue-Plasminogen Activation with Nitroglycerin, Heparin, Lidocaine, Dobutamine and Dopamine," Am. J. Hosp. Pharm. 47, 606 (1990).
    Alexander, K.S., Azizi, J., Dollimore, D. and Uppala, V., "The Interpretation of the Hindered Setting of Calcium Carbonate Suspensions in Terms of Permeability," J. Pharm. Sci., 79, 401 (1990)
  • Gupchup, G.V., Alexander, K.S., Dollimore, D., Lee, Y.F. and Wilburn, F.W., The Solid State Thermal Degradation of Aspirin Proceeding 19th NATAS Conference, (Editor I.R. Morrison). Boston, Mass. Vol II, pp. 549-555. (1990)
  • Alexander, K.S., Haribhakti, R.P. and Parker, G.A., Stability of Acetozolamide in Suspension Compounded from Tablets, Am. J. Hosp. Pharm. 48(6), 1241-44 (1991)
  • Harbhakti, R.P., Alexander, K.S. and Parker, G.A., An Improved High Performance Liquid Chromatography Assay for Acetazolamide, Drug Development and Indust. Pharm., 17(6), 805-815 (1991)
  • Alexander, K.S., Dollimore, D., Tata, S.S. and Uppala, V., A Comparison of the Coefficients in the Richardson and Caki's and Steinour's Equations Relating to the Behavior of Concentrated Suspensions, Separation Science and Technology, 26(6), pp. 819-829 (1991)
  • Gupchup, G.V., Alexander, K.S. and Dollimore, D., The Use of Thermal Analysis and Mass Spectrometry To Study The Solid State Behavior in Pharmaceutical Tablet Mixtures, Thermochemica Acta, 196, pp. 267-78 (1992)
  • Alexander, K.S., Dollimore, D., Murthy, A.S. and Tata, S.S. An Improved Method of Calculating Floc Size in Concentrated Pharmaceutical Suspensions by Noting Corrections for Density, Viscosity and Initial Porosity, S.T.P. Pharma, 1(6), 369-378 (1992)
  • Azizi, J., Alexander, K.S., Dollimore, D., Murthy, A.S. and Tata, S.S., The Development of a Permeability Theory Applied to Concentrated Suspensions, Colloids and Surfaces, 62, 1-9 (1992)
  • Alexander, K.S., Dollimore, D. and Murthy, A.S., Investigation of Sedimentation Parameters of Concentrated Aluminum Hydroxide Slurries, Proceedings of the 11th Pharmaceutical Technology Conference, Vol. III, pp. 112-135 (1992)
  • Alexander, K.S., Dollimore, D., Tata, S.S. and Murthy, A.S. The Influence of the Dielectric Constant on the Sedimentation Rate of Concentrated Suspensions of Aluminum and Magnesium Hydroxide, J. Pharm. Sci. 81(8), 787-790, 1992.
  • Pudipeddi, M., Alexander, K., Parker, G.A. Carstensen, J., Decomposition Profiles of Oxygen, Sensitive Drugs in the Presence of Antioxidant; Drug Development and Industrial Pharmacy; 18(20), 2135-43, 1992.
  • Knapp, A.S., Mauro, V., and Alexander, K.S., Incompatibility of Ketorolac with Selected Postoperative Drugs, Am. J. Hosp. Pharm., 49, 2960-62, 1992.
  • Alexander, K.S., Pudipeddi, M. and Parker, G.A., Stability of Procainamide HCl Syrup Compounded from Capsules, Am. J. Hosp. Pharm., 50, 693-96, 1993.
  • Alexander, K.S., Pudipeddi, M. and Parker, G.A., Stability of Hydralazine HCl Syrup Compounded from Tablets, Am. J. Hosp. Pharm., 50, 683-86, 1993.
  • Alexander, K.S., Dollimore, D., Dunn, J.G., Gao, X. and Patel, D., The Determination of Cholesterol, Calcium Carbonate and Calcium Oxalate in Gallstones by Thermogravimetry, Thermochemica Acta, 215, 171-81, 1993.
  • Skelton, Jr., J.D., Alexander, K.S., Dollimore, D., Berman, C. and Miller L., The Influence of Pectin and the Bile Salt-Lecithin-Cholesterol System on the Particle Size of Calcium Carbonate Suspensions, STP Pharma, 3(2), 153-62, 1993.
  • Heda, P., Dollimore, D., Alexander, K.S., Chen, D., Law, E. and Bicknell., A Method of Assessing Solid State Reactivity Illustrated by Thermal Decomposition Experiments on Sodium Bicarbonate, Thermochemica Acta, V. 255, 255 - 272, May 1, 1995.
Last Updated: 3/22/15