The University of Toledo

MBC Graduate Courses

Graduate Catalog

The following is a complete list of the graduate courses currently offered by the Department of Medicinal & Biological Chemistry:

• MBC - 5100 RESEARCH PRACTICES IN MEDICINAL CHEMISTRY [1 hour] Consideration of the scientific, ethical, and legal obligations of the graduate student researcher. Prerequisite: Admission to the graduate program in medicinal chemistry, chemistry, biology, pharmaceutical sciences, or permission of instructor
  
  
• MBC - 5620 BIOCHEMICAL TECHNIQUES [2 hours] A detailed study of biochemical laboratory techniques necessary for the development of novel therapeutics, including bioassays and data analysis. Prerequisite: Admission to the graduate program in medicinal chemistry, chemistry, biology, or pharmaceutical sciences, or permission of instructor
  
  
• MBC - 5900 MEDICINAL CHEMISTRY SEMINAR [1 hour] Presentation and discussion of advanced research topics in medicinal chemistry will be presented and argued with an emphasis on evaluating and criticizing emerging data as a way of testing hypotheses. Prerequisite: Admission to graduate program in medicinal chemistry, chemistry, biology, or pharmaceutical sciences, or permission of instructor
  
  
• MBC - 6100 ADVANCED IMMUNOLOGY [2 hours] Readings in and critical analysis of the recent literature in immunology and basic immunologic responses, especially as considered in immunotherapy. Prerequisite: Admission to Ph.D. program in chemistry, medicinal chemistry, or biology, and permission of the instructor.
  
  
• MBC - 6190 ADVANCED MEDICINAL CHEMISTRY [4 hours] Discussion of the qualitative and quantitative aspects of the design of new therapeutic agents. Approaches to the design of drugs and new therapeutic modalities directed at enzymes, receptors, membrane transport proteins and nucleic acids are examined. Prerequisite: Admission to the graduate program in medicinal chemistry, biology, or pharmaceutical sciences, or permission of instructor
  
  
• MBC - 6200 BIOMEDICINAL CHEMISTRY [4 hours] Examination of the primary literature on approaches to the design of new therapeutic agents. Recent novel directions in the design of drugs will be examined and compared. Prerequisite: MBC 6190 or permission of instructor
  
  
• MBC - 6300 BIOMEDICINAL CHEMISTRY LABORATORY I [4 hours] Experimental research problems in biomedicinal chemistry. Prerequisite: MBC 6190, 6550
  
  
• MBC - 6310 BIOMEDICINAL CHEMISTRY LABORATORY II [4 hours] Additional experimental research problems in biomedicinal chemistry (see MBC 6300). Prerequisite: MBC 6190, 6550 or permission of course director
  
  
• MBC - 6420 PROTEIN CHEMISTRY [4 hours] A detailed analysis of the structure and function of proteins: current methodology for the analysis of structure, the basis for molecular associations, and relationships between structure and biological function. Prerequisite: MBC 6550 or equivalent
  
  
• MBC - 6430 NUCLEIC ACID CHEMISTRY [4 hours] The chemical basis for storage and transmission of genetic information. Prerequisite: MBC 6550 or equivalent
  
  
• MBC - 6440 ENZYMOLOGY [4 hours] The principles of chemical catalysis applied to molecular enzymology. Prerequisite: MBC 6550 or equivalent
  
  
• MBC - 6550 BIOCHEMISTRY [4 hours] A consideration of the structure and function of biological macromolecules as well as the basic and regulated metabolism of cells. Prerequisite: Admission to Graduate Program in medicinal chemistry, chemistry, biology, or pharmaceutical sciences, or permission of instructor; undergraduate course in Organic Chemistry
  
  
• MBC - 6750 BIOORGANIC CHEMISTRY: CHEMICAL APPROACHES TO ENZYMES [2 hours] An advanced course in the application of organic chemistry, stereochemistry, synthesis and kinetics to the study of enzymes, enzyme inhibition and enzyme mechanisms. Prerequisite: MBC 6550 and a graduate course in Organic Chemistry, or permission of instructor
  
  
• MBC - 6800 METHODS IN BIOTECHNOLOGY [3 hours] Experimental investigations of current techniques in biochemistry and molecular biology that involve DNA or protein amplification, modification, and interactions relevant to drug research. Prerequisite: MBC 6550
  
  
• MBC - 6960 M.S. THESIS RESEARCH IN MEDICINAL CHEMISTRY [1 - 15 hours] Dewvelopment and pursuit of research leading to an M.S. thesis in medicinal chemistry. Prerequisite: Admission to M.S. program in medicinal chemistry
  
  
• MBC - 6980 SPECIAL TOPICS IN BIOMEDICINAL CHEMISTRY [1 - 5 hours] Selected study of topics in medicinal chemistry. New chemical and biochemical strategies in drug design are examined in detail. Prerequisite: Admission to graduate program in medicinal chemistry, chemistry, biology, or pharmaceutical sciences, or permission of instructor
  
  
• MBC - 7100 RESEARCH PRACTICES IN MEDICINAL CHEMISTRY [1 hour] Scientific, ethical and legal obligations of the graduate student researcher will be considerd. Prerequisite: Admission to graduate program in medicinal chemistry, chemistry, biology, or pharmaceutical sciences, or permission of instructor
  
  
• MBC - 7620 BIOCHEMICAL TECHNIQUES [2 hours] A detailed study of biochemical laboratory techniques necessary for the development of novel therapeutics, including bioassays and data analysis. Prerequisite: Admission to the graduate program in medicinal chemistry, chemistry, biology, or pharmaceutical sciences, or permission of instructor
  
  
• MBC - 7900 MEDICINAL CHEMISTRY SEMINAR [1 hour] Presentation and discussion of advanced research topics in medicinal chemistry will be presented and argued with an emphasis on evaluating and criticizing emerging data as a way of testing hypotheses. Prerequisite: Admission to Ph.D. program in medicinal chemistry, chemistry, biology, or pharmaceutical sciences, or permission of instructor
  
  
• MBC - 8100 ADVANCED IMMUNOLOGY [2 hours] Readings in and critical analysis of the recent literature in immunology and basic immunologic responses, especially as considered in immunotherapy. Prerequisite: Admission to Ph.D. program in chemistry, medicinal chemistry or biology and permission of the instructor
  
  
• MBC - 8190 ADVANCED MEDICINAL CHEMISTRY [4 hours] Discussion of the qualitative and quantitative aspects of the design of new therapeutic agents. Approaches to the design of drugs and new therapeutic modalities directed at enzymes, receptors, membrane transport proteins and nucleic acids are examined. Prerequisite: Admission to the graduate program in medicinal chemistry, chemistry, biology, or pharmaceutical sciences or permission of instructor.
  
  
• MBC - 8200 BIOMEDICINAL CHEMISTRY [4 hours] Examination of the primary literature on approaches to the design of new therapeutic agents. Recent novel directions in the design of drugs will be examined and compared. Prerequisite: MBC 8190 or permission of instructor
  
  
• MBC - 8300 BIOMEDICINAL CHEMISTRY LABORATORY I [4 hours] Experimental research problems in biomedicinal chemistry. Prerequisite: MBC 8190, MBC 8550
  
  
• MBC - 8310 BIOMEDICINAL CHEMISTRY LABORATORY II [4 hours] Additional experimental research problems in biomedicinal chemistry (see MBC 8300). Prerequisite: MBC 8190 and MBC 8550; or permission of course director
  
  
• MBC - 8420 PROTEIN CHEMISTRY [4 hours] A detailed analysis of the structure and function of proteins: current methodology for the analysis of structure, the basis of molecular associations, and relationships between structure and biological function. Prerequisite: MBC 8550 or equivalent
  
  
• MBC - 8430 NUCLEIC ACID CHEMISTRY [4 hours] The chemical basis for storage and transmission of genetic information. Prerequisite: MBC 8550 or equivalent
  
  
• MBC - 8440 ENZYMOLOGY [4 hours] The principles of chemical catalysis applied to molecular enzymology. Prerequisite: MBC 6550 or equivalent
  
  
• MBC - 8550 BIOCHEMISTRY [4 hours] A consideration of the structure and function of biological macromolecules as well as the basic and regulated metabolism of cells. Prerequisite: Admission to Graduate Program in medicinal chemistry, chemistry, biology, pharmaceutical sciences or permission of instructor. Undergraduate course in organic chemistry
  
  
• MBC - 8750 BIOORGANIC CHEMISTRY: CHEMICAL APPROACHES TO ENZYMES [2 hours] An advanced course in the application of organic chemistry, stereochemistry, synthesis, and kinetics to the study of enzymes, enzyme inhibition and enzyme mechanisms. Prerequisite: MBC 8550 and a graduate course in Orgamic Chemistry, or permission of instructor
  
  
• MBC - 8800 METHODS IN BIOTECHNOLOGY [3 hours] Experimental investigations of current techniques in biochemistry and molecular biology that involve DNA or protein amplification, modification, and interactions relevant to drug research. Prerequisite: MBC 8850 or equivalent
  
  
• MBC - 8960 PH.D. DISSERTATION RESEARCH IN MEDICINAL CHEMISTRY [1 - 15 hours] Development and pursuit of research leading to a Ph.D. dissertation in medicinal chemistry. Prerequisite: Admission to Ph.D. program in medicinal chemistry
  
  
• MBC - 8980 SPECIAL TOPICS IN BIOMEDICINAL CHEMISTRY [1 - 5 hours] Selected study of topics in medicinal chemistry. New chemical and biochemical strategies in drug design are examined in detail. Prerequisite: Admission to Ph.D. program in medicinal chemistry, chemistry, or biology, or permission of instructor.