The University of Toledo

MBC Undergraduate Courses

The following is a complete list of the undergraduate courses currently offered by the Department of Medicinal & Biological Chemistry:

• MBC - 3310 MEDICINAL CHEMISTRY I: DRUG ACTION AND DESIGN [3 hours] An introductory course presenting the basic chemical principles governing the behavior of drugs and the design of new therapeutics. Prerequisite: CHEM 2420 Corequisite: MBC 3550
  
  
• MBC - 3320 MEDICINAL CHEMISTRY II: - [3 hours]
  
  
• MBC - 3550 PHYSIOLOGICAL CHEMISTRY I: STRUCTURE AND FUNCTION OF BIOLOGICAL MACROMOLECULES [3 hours] An examination of the levels of structure of proteins, nucleic acids, other biomolecules, and biomolecular assemblies. Prerequisite: CHEM 2420 or completion of one year of Organic Chemistry
  
  
• MBC - 3560 PHYSIOLOGICAL CHEMISTRY II: CHEMICAL REGULATION OF CELLS AND ORGANISMS [3 hours] An examination of the chemistry and regulation of metabolic processes in cells, interacting cells, and tissues. Prerequisite: MBC 3550 or equivalent
  
  
• MBC - 3800 MICROBIOLOGY AND IMMUNOLOGY [3 hours] A lecture course with an emphasis on how the immune system protects the body against bacterial, viral, and parasitic invaders. Medically important human infectious diseases are described, along with chemotherapeutic intervention. Prerequisite: MBC 3550 Corequisite: MBC 3560
  
  
• MBC - 3850 MICROBIOLOGY AND IMMUNOLOGY LAB [1 hour] Lab course associated with MBC 3800. Laboratory on immunology and microbiology techniques. Prerequisite: MBC 3550 Corequisite: MBC 3560, MBC 3800 and admission to the professional division in pharmacy.
  
  
• MBC - 4300 MEDICINAL CHEMISTRY III: CHEMOTHERAPY AND IMMUNOTHERAPY [3 hours] The chemical bases for actions of drugs that counter infectious disease and cancer, including the use and modulation of the immune system and its products to target infectious disease and cancer. Prerequisite: MBC 3600 or BIOL 4030 & BIOL 4050
  
  
• MBC - 4340 CONTEMPORARY NATURAL REMEDIES [2 hours] An introduction to natural remedies, their history, source, chemical constituents, documented therapeutic utility, and toxicity. Prerequisite: MBC 3320 or permission of instructor
  
  
• MBC - 4380 MEDICINAL PLANTS [2 hours] A lecture / field course emphasizing medicinal and poisonous plants of this locale. Prerequisite: Admission to professional division BS program in pharmacy
  
  
• MBC - 4390 GENES AND PROTEINS IN THERAPY [2 hours] Consideration of the symptoms, molecular nature, current treatment, and amelioration by gene therapy of diseases caused by gene and protein defects. Prerequisite: MBC 3550
  
  
• MBC - 4410 NUTRITION IN HEALTH AND DISEASE [2 hours] A comprehensive examination of the role of carbohydrates, lipids, proteins, vitamins, and minerals in maintaining good health, as well as our current understanding of the interplay between nutrition and disease. Prerequisite: MBC 3560
  
  
• MBC - 4420 NEUROSCIENCE [2 hours] An examination of the basic anatomy, chemistry, and physiology of neural systems. The organization of the brain and its role in behavior and in disease states are presented in an interdisciplinary way. Prerequisite: MBC 3560
  
  
• MBC - 4430 BIOCHEMISTRY OF DISEASE [2 hours] Mechanisms of pathogenesis and pathophysiological consequences in diseases already well-understood at a biochemical level. Emphasis is placed on the logic behind existing and future drug therapies in disease. Prerequisite: MBC 3560
  
  
• MBC - 4450 NEW DRUG DEVELOPMENT [2 hours] An examination of all phases of drug discovery and development from conception to marketing: case histories from pharmaceutical research and development. Prerequisite: MBC 3560 or permission of instructor
  
  
• MBC - 4470 ADVANCED IMMUNOTHERAPEUTICS [2 hours] This course emphasizes the development of methods for immunotherapeutic intervention in cancer and autoimmune and infectious disease. The course has a seminar / discussion / student presentation format. Prerequisite: MBC 4300
  
  
• MBC - 4480 CHEMICAL DEFENSE MECHANISMS IN PLANTS [2 hours] A study of the effects on plant predators of secondary metabolites in plants as a basis for the novel development of therapeutics. Prerequisite: MBC 3560
  
  
• MBC - 4710 TARGETED DRUG DESIGN [3 hours] A survey of novel macromolecular targeting approaches to drug design in important human disorders. The course has a seminar / discussion / student presentation format. Prerequisite: MBC 3320
  
  
• MBC - 4720 ADVANCES IN DRUG DESIGN [3 hours] A survey of novel approaches to drug design and development. The course has a seminar / discussion / student presentation format. Prerequisite: MBC 3320
  
  
• MBC - 4760 BIOCHEMICAL TOXICOLOGY [2 hours] The biochemical principles underlying toxicological phenomena, including biotransformation, host and environmental modulation, and target organs. Prerequisite: MBC 3550 Corequisite: MBC 3560
  
  
• MBC - 4770 MOLECULAR MODELING IN DRUG DESIGN [3 hours] Theoretical and graphical approaches to the geometry of drug interactions with their receptors. Methods of determining and predicting conformation at drug receptor sites are examined. Prerequisite: MBC 3320
  
  
• MBC - 4800 QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS [2 hours] Linear free energy relationships and substituent effects in pharmacologically related agents are considered in the quantitative description of structure vs. drug activity. Prerequisite: MBC 3320
  
  
• MBC - 4900 HONORS SEMINAR IN MEDICINAL AND BIOLOGICAL CHEMISTRY [3 hours] An examination of a specific question in the context of the primary literature in medicinal or biological chemistry. Prerequisite: Permission of College of Pharmacy Honors Program Advisor
  
  
• MBC - 4910 PROBLEMS IN BIOMEDICINAL CHEMISTRY [1 - 3 hours] Selected study of topics in biomedicinal chemistry. New chemical and biochemical strategies in drug design are examined in detail. Prerequisite: 4th year status (professional division --BS Pharm Prog)
  
  
• MBC - 4950 RESEARCH IN MEDICINAL CHEMISTRY [6 - 8 hours] Selected research and study in medicinal chemistry. Prerequisite: Permission of instructor
  
  
• MBC - 4960 HONORS THESIS IN MEDICINAL AND BIOLOGICAL CHEMISTRY [2 - 5 hours] An examination of a specific research question in medicinal or biological chemistry that can be answered through experimental work. Prerequisite: Permission of College of Pharmacy Honors Program Advisor
  
  
• MBC - 4980 SPECIAL TOPICS IN DRUG DESIGN [1 - 4 hours] A detailed examination of new chemical and biochemical strategies in drug design. Prerequisite: MBC 3320, 3560