The University of Toledo | Providing Hope

Providing Hope

UToledo researchers are advancing new therapies for brain diseases through innovations in medicinal chemistry.

Through a deeper understanding of proteins and molecules in targeted areas of the brain, University of Toledo researchers are working to develop better treatment options for those living with diseases of the brain.

Isaac Schiefer working out an equation on a white board

Alzheimer's Disease

UToledo Assistant Professor Isaac Schiefer, Ph.D., has received grants totaling more than $2 million from the National Institutes of Health to advance development of a prototype molecule designed to increase proteins important for long-term memory and to study their ability to heal damaged brain cells. Schiefer is among the youngest researchers to receive NIH support at this level.

Dr. Isaac Schiefer

Addiction

Dr. Schiefer also has been funded by the National Institute on Drug Abuse to study drug targets to addiction centers in the brain in a search for methods of addressing or preventing drug addiction.

Stroke

Ph.D.-candidate Kevin Nash was among 38 students nationally to be funded for his drug design research into development of an enzyme-inhibitor to protect neurons and other brain cells from damage during a stroke.

Kevin Nash conducting research

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