Congratulations to CAB Alumni Michael Robinson, PhD
Mike will be awarded the Doctor of Medicine/Doctor of Philosophy in Biomedical Sciences
Program Outstanding Student award at The Class of 2015 Graduation Awards Ceremony
on May 28. He completed his PhD training in June 2013 in the labs of Dr. William Maltese and Dr. Paul Erhardt.
2015 Graduate Research Forum Cancer Biology Student Finalists
Congratulations to Cancer Biology students Kari Lavik (Eisenmann lab) for 1st place oral presentation and Ila Datar (Yeung lab) for 3rd place poster presentation at the 2015 Graduate Research Forum. There
were 34 competing students from all four Biomedical Sciences tracks and the College
of Pharmacy. Each winner went through 2-3 rounds of screening to win their awards.
The Keynote Speaker this year was Dr. Keith T. Flaherty, MD, Associate Professor of
Medicine, Harvard Medical School, Director of Developmental Therapeutics, Cancer Center,
Massachusetts General Hospital. Dr. Flaherty's seminar was entitled "Leveraging Molecular
Biology in Cancer Therapy to Develop Rationale Targeted therapy: the Case Made by
Cancer Biology Students Receive Scholarships
Gaurav Mehta (de la Serna lab) has been named the 2015 Robert N. Whiteford Memorial Scholarship recipient.
This award is presented to a graduate student to assist in research for thesis, project
or dissertation and further the student's professional development.
Archit Trivedi (de la Serna lab) received the 2014-2015 GSA Graduate Research Award. The funds will be used
for his research entitled "Role of Bromodomain Containing Proteins in SWI/SNF Mediated
Dr. Lijun Liu Receives Travel Grant
Dr. Lijun Liu, Assistant Professor of Biochemistry & Cancer Biology, has been awarded a travel
grant from the Foy & Phyllis Penn Kohler Fund for International Studies Studies to
support her research collaboration with Aarhus University in Denmark. The travel
grant program provides support to carry out activities that directly benefit the University
of Toledo by internationalizing the campus and/or curriculum. She will travel to
Denmark this spring to meet with her collaborator Dr. Natalya Fedosova.
Manning Paper 2nd Most Highly Cited Publication in Journal of Neuroendocrinology
Dr. Manning recently received a letter from Dr. Tehmina Amin, Managing Editor, Journal
of Neuroendocrinology, notifying him and his co-authors that their paper*, with 16
citations, was the second most highly cited paper in the journal in 2013.
*Manning, M., Misicka, A., Olma, A., Bankowski, K., Stoev, S., Chini, B., Duroux,
T., Mouillac, B., Corbani, M., and Guillon, G. (2012) Oxytocin and Vasopressin Agonists and Antagonists as Research Tools and Potential
Therapeutics. J. Neuroendocrinol., 24:609-628.
Cancer Biology Students Receive Travel Awards
Congratulations to Cancer Biology students, Shweta Aras and Archit Trivedi, recipients
of two travels awards to the 2014 International Pigment Cell Conference to be held
in Singapore, Malaysia, Sept. 4-7, 2014. They both were awarded $1,000 each from
the International Federation of Pigment Cell Society and $600 each from the PanAmerican
Society for Pigment Cell Research.
||Shweta will present an oral presentation on her work entitled "To Investigate the
Role of Baf60a in Melanocyte Differentiation"
||Archit will present a poster on his work entitled "The Role of BRD4 in Melanogenesis"
Both students are mentored by Dr. Ivana de la Serna
Cancer Biology Student Articles Published in the Toledo Blade
The Toledo Blade is publishing a series of articles written by Biomedical Sciences
students here at the University of Toledo College of Medicine & Life Sciences. Following
are the first two in the series by our Cancer Biology students:
Shweta Aras (2/2/15) - Shining a light on the darkness of melanoma
Ila Datar (10/13/14) - The ongoing battle against melanoma
Akshada Sawant (5/5/14) - UT doctoral students fight to tame cancer genes
Jessica Arden (6/2/14) - Stopping cell movement in glioblastoma
Cancer Biology Student Finalists in 2014 Graduate Research Forum
Congratulations to Cancer Biology students Nneka Mbah, Gaurav Mehta and Meghan Wyse
for their wins at the 2014 Graduate Research Forum. A total of 38 students participated
from all four Biomedical Sciences tracks and the College of Pharmacy. Each winner
went through 2-3 rounds of screening to win their awards.
Nneka Mbah (Maltese lab) Gaurav Mehta (de la Serna lab) Meghan Wyse (Eisenmann lab)
1st Place Poster Presentation 1st Place Oral Presentation
2nd Place Oral Presentation
Congratulations to Cancer Biology student, Nneka Mbah
Congratulations to Nneka Mbah (Maltese lab) for winning 3rd place in the Oral Presentation category at the Graduate Student
Association 5th Annual Midwest Graduate Research Symposium held March 29, 2014. The
symposium has been recognized as a premier event and offers great opportunities for
student to present their research, networking, and fostering intercollegiate friendships
Ms. Mbah also received a $1,500 Millennium Scholar-in-Training award from the American
Association for Cancer Research. The award provides financial support for AACR meeting
attendance to offset expenses incurred attending the program. Nneka presented a
poster at the AACR annual meeting (San Diego, April 5-9) entitled "Non-apoptotic death
induced in glioma cells by the indole-based chalcone, MOMIPP, involves disruption
of endolysosomal trafficking and ER stress" (N.E. Mbah, A.D. Trunk, B.A. Dewitt, J.H. Overmeyer and W.A. Maltese).
Dr. de la Serna Receives Research Award from Melanoma Know More
Congratulations to Dr. Ivana de la Serna on receiving the 2013 Melanoma Know More
research grant for her research on the role of epigenetic regulators in melanocyte
development. Melanoma Know More is a Cincinnati-based, grass-roots organization that was formed in 2006 to generate
awareness and education about melanoma and the importance of early detection and prevention.
Biochemistry & Cancer Biology Faculty Receive 2013 Deans Awards
Congratulations to Dr. Kathryn Eisenmann and Dr. Cynthia Smas on receiving 2013 Dean Awards for research and teaching.
Dr. Eisenmann was selected as the recipient of a 2013 College of Medicine & Life Sciences
Dean's Award for Research in the New Investigator category. Dr. Smas received the
2013 College of Medicine & Life Sciences Dean's Award for Teaching Excellence in Basic
Sciences. Both were strongly support by their chair, peers and by student representatives
for these awards. They were honored at the University of Toledo College of Medicine
& Life Sciences Faculty Recognition Reception held on October 10.
(photo courtesy of Dr. Maurice Manning)
Life-Saving compound developed and patented at UToledo licensed to Prolong Pharmaceuticals
UTNews - December 2, 2013, By Jon Strunk
A compound developed at The University of Toledo that can be used to prevent blood
vessels from leaking fluid into surrounding tissue following a traumatic injury to
the human body has been licensed to Prolong Pharmaceuticals LLC, South Plainfield,
NJ, for continued development and commercialization.
The invention uses polyethylene-glycol (PEG) to modify albumin, a protein found in
blood, to expand the blood’s volume and prevent it from escaping through holes in
“The University of Toledo is proud of our role in developing this technology that
has the potential to save lives and limit the internal fluid leakage that can lead
to multi-organ dysfunction and failure, and even death,” UT President Dr. Lloyd Jacobs
said. “This technology is an example of the great contribution the science developed
and patented at The University of Toledo can have on people around the globe.”
The technology – developed by Dr. Ragheb Assaly, professor of medicine, Dr. David Dignam, professor of biochemistry and Dr. Joseph Shapiro a former professor of nephrology and now dean of the Marshall
University medical school – promises to become the optimal blood volume expander to
prevent decreased blood volume caused by severe burns, hemorrhagic shock, sepsis,
anaphylaxis, traumatic brain injury, adult respiratory distress syndrome and other
PEG-albumin has been tested in animal models and in all cases has demonstrated superiority
to regular albumin as a plasma expander.
“The university is excited to enter into this license with Prolong Pharmaceuticals
for the development and commercialization of this technology,” said Stephen Snider,
vice president of technology transfer and associate general counsel. “This collaboration
with Prolong will serve to bring this life-saving treatment to patients and further
UT’s mission to improve the human condition.”
Prolong Pharmaceuticals is developing products to treat several diseases and their
debilitating co-morbidities that reduce quality of life and increase medical cost
For more information, go to prolongpharma.com
|Cover image of August 2013 issue of The Journal of Pharmacology and Experimental Therapeutics
|The Journal of Pharmacology and Experimental Therapeutics chose to highlight a structural
homology model of a monomeric mouse oxytocin receptor on their August 2013 cover.
The figure was published from the article "Selective and Potent Agonist and Antagonists
for Investiging the Role of Mouse Oxytocin Receptors" by M. Busnelli, E. Bulgheroni,
M. Manning, G. Kleinau, and B. Chini (pp. 381-327).
Dr. Manning named UT COM Student Ombudsman
An Ombudsman is generally defined as a representative of an organization whose position
is designed to investigate complaints and suggest solutions. Within a university,
the Ombuds helps students resolve concerns, problems or conflicts with regards to
university policies, procedures and decisions. The Ombuds will provide a confidential
and neutral place for students to come to express their concerns and work to identify
options for a successful resolution of their problem. This does not take the place
of other formal processes, but acts as an additional option to guide conflict resolution.
The University of Toledo College of Medicine and Life Sciences is happy to announce
that Maurice Manning, Ph.D., D.Sc. has agreed to serve as the Ombuds for the College
of Medicine and Life Sciences. Dr. Manning is a Distinguished University Professor
in the Department of Biochemistry and Cancer Biology. He has been widely recognized
for his excellence in teaching having received the Deans Award for Teaching Excellence
and 13 Golden Apple Teaching Awards. He is also a renowned researcher whose work
on peptide ligands for vasopressin and oxytocin receptors has contributed significantly
to the scientific literature. Many of these peptides have been utilized as research
tools in laboratories worldwide and have helped to advance continuing research in
the oxytocin vasopressin field. In addition to his teaching and research excellence,
he has been an outstanding mentor to many students through the years. It is his true
caring for his students and the University that makes him an excellent person to be
our Ombuds. Dr. Manning can be reached at (419) 383-4143 for appointments.
University of Toledo WIRED Newsletter, March 26, 2013
Biochemistry & Cancer Biology department research highlighted
A recent Rocket Science publication highlights research by several members of the Department of Biochemistry
& Cancer Biology. This includes articles describing the research of Dr. Kam Yeung
on the function of the RKIP protein in slowing the growth and spread of cancer cells;
Dr. Ivana de la Serna on the role of modifications of chromatin structure for cancer
treatment; Drs. Kandace Williams and Steve Patrick exploring how DNA repair pathways
may be exploited to boost effectiveness of cancer therapies; Dr. Manohar Ratnam on
development of new therapies for breast and prostate cancers; and that of department
chair, Dr. William Maltese, on gene-based strategies to kill glioblastoma cells.