Neurosciences and Neurological Disorders

Program Overview (Ph.D.)

The Neurosciences and Neurological Disorders training program at the University of Toledo on the Health Science Campus offers the Ph.D., M.D./Ph.D., and M.S.B.S. degrees through the interdisciplinary degree programs in Medical Sciences. The primary goal of the doctoral program in Neurosciences and Neurological Disorders is to train students for independent, creative careers in research and/or teaching. The curriculum for the Ph.D. degree consists of a core of concentrated course work in the first year, followed by specialized elective courses and an emphasis on laboratory research. Elective courses are offered in developmental and systems neuroscience, as well as ion channel function, sensory physiology, and neuropharmacology. During the first two semesters, each student rotates through four research laboratories, conducting short-term projects, gaining exposure to techniques and identifying potential areas for further investigation. At the end of the second semester, each student selects a major advisor who directs the student's doctoral research. A faculty committee is also jointly chosen by the student and advisor to supervise academic progress toward completion of the Ph.D. degree.

Program Learning Outcomes for Neurosciences and Neurological Disease and Disorders
Core Knowledge 1. Identify and summarize the structure and function of cells, tissues, and organs C2. Describe the molecular, biochemical, and cellular mechanisms that maintain the normal function, development, and plasticity of cells, tissues, and organs C3. Summarize basic disease causes and processes that affect the structure and function of cells, tissues, and organs C4. Assess and critically analyze relevant basic science and clinical literature. C5. Design and conduct applicable biomedical sciences experiments C6. Organize, interpret and summarize results of applicable biomedical sciences experiments. C7. Demonstrate ethical and responsible conduct in research and all other scholarly activities consistent with the University of Toledo, Health Science Campus, Standards of Conduct

Specialized Knowledge 1 Demonstrate knowledge of normal structure and function of the body and its major organ systems, with emphasis on the peripheral and central nervous system. K2 Describe the molecular, biochemical, and cellular mechanisms which are important in homeostatic maintenance of normal nervous system function. K3 Summarize and explain the basic neurophysiology of excitable membranes. K4 Demonstrate knowledge of neurophysiological basis of behavior in health and disease. K5 Distinguish classical and contemporary models of changes in nervous system function in response to changes in intrinsic or extrinsic environmental stimuli throughout the lifespan. K6 Relate nervous system structure and function in normal and disease states as studied with contemporary techniques and related translational research approaches. K7 Identify the pathophysiological underpinnings of prominent neurological disorders (e.g.. cognitive disorders, movement disorders, neurodevelopmental disorders, seizure disorder, substance use disorders). K8 Demonstrate knowledge of basic principles of pharmacology (drug action) and pharmacology of specific drugs and toxins used in basic neuroscience research, in vino and in vitro, and in the treatment of prominent neurological disorders. K9 Apply the use of statistical methods to appropriately design, analyze and interpret research projects. K10 Describe and employ the principles that govern ethical and legal decision making in the design and conduct of research projects, and the accurate reporting of the results. K11 Distinguish the various approaches to the organization and financing of biomedical research projects. 

Integrative Skills 1 The ability to perform selected basic laboratory procedures that are commonly used in the laboratories of most track faculty. results. I2 The ability to perform advanced/specialized procedures that are necessary for the completion of the student's assigned dissertation research projects (s). I3 The ability to design and complete independent research projects, and the ability to perform productively as a member of a research team. I4 The ability to communicate effectively, both orally and in writing, with colleagues, faculty, scientific journal editors/reviewers, and research granting agencies. I5 The ability to retrieve (from electronic databases and other sources), manage, and utilize biomedical information for hypothesis development and solving problems that are relevant to the appropriate completion of a research project, and the accurate reporting of the results. I6 The ability to present their results at local, national and international meetings as well as to be able to organize and chair local meetings I7 The ability to write and submit manuscripts and to communicate effectively with scientific journal editors and reviewers I8 The ability to write a comprehensible research proposal and raise funds to support it from federal, state and other funding agencies 

Professionalism 1 Demonstrate ethical, responsible, reliable, and dependable behavior in all aspects of their professional lives, and a commitment to the profession and to society. P2 Demonstrate honesty and integrity in all interactions with colleagues, research subjects, and others with whom students may interact in their professional lives. P3 Demonstrate professionalism in dress and grooming related to compliance with health and safety rules applicable to research laboratories, and other research sites. P4 Demonstrate compassionate treatment of patients as subjects of research, and respect for their privacy and dignity. P5 Demonstrate compassionate treatment of experimental animals, and respect for all laws and regulations applicable to the use of animals in biomedical research. 

Team Science1 Demonstrate ability to integrate and apply content knowledge and experience in complex projects and assignments, including collaborative efforts. T2 Demonstrate proficiency in the analysis and evaluation of scientific literature and data within collaborative groups including laboratory research teams, manuscript review courses, grant review panels and scientific focus groups. T3 Demonstrate proficiency in the design and creation of a new original, collaborative work including scientific manuscript for peer-reviewed publication, a journal review article for publication and summaries of focus group discussions.

Core Courses

Fall Semester

 Credit hours

 


BMSP 633/833 CPRA Protein Struc & Catalysis
BMSP 634/834 CPRA Genes & Genomes
BMSP 636/836 CPRA Cell Membranes
BMSP 638/838 Methods in Biomed Sci
INDI 602/802 On Being a Scientist
Intro to Biomed Research
BMSP 639/839 Mentored Research (rotation) (8wk)


2
2
2
2
0
0
1

 
Spring Semester    

BMSP 635/835 CPRA Cell Biology & Signaling
BMSP 631/831 Systems Pathophysiology I
BMSP 632/832 Systems Pathophysiology II
BMSP 603/803 Journal Paper Review in NND
BMSP 639/839 Mentored Research (rotation) (2 x 8wk)


3
2
2
1

 
Summer Semester    


PUBH 532 Statistical Methods I


3

 

Track or Major Courses

Spring Semester    


NND 650/850 Seminar in Neuroscience
NND 654/854 Journal Paper Review in Neurosciences
BMS 603/803 Journal paper review


0
1
1

 

 

 

 

Elective Courses

Fall Semester    


BIOE 4720/5620 Cellular Electrophysiology
NND 689/889 Independent study in Neuroscience
NND 656/856 Readings in Neuroscience
672/872 Current Topics in Neuroscience


3
1-12

1-5

 
Spring Semester    


BMSP 625/825 Grant Writing Workshop
NND 581/781 Neuroscience
NND 689/889 Independent study in Neuroscience
NND 656/856 Readings in Neuroscience
672/872 Current Topics in Neuroscience

Cvmd 640/840 Basic principles of Pharmacology 1
INDI679/879. Microscopy Techniques I: Basic and Advanced Light Microscopy:

INDI686/886. Microscopy Techniques II: Transmission and Scanning Electron Microscopy:
Neuropharmacology


2
6
1-12

1-5

 
     
 

 

 
Research Courses

Fall - Spring and Summer Semester    


NND 699/899 Research in Neuroscience
INDI 999 Dissertation Research (30 min)


1-12
1-12

 


Please mail questions, comments, and suggestions to Dr. Giovannucci.
Last Updated: 6/21/22