Department of Biological Sciences


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Phone: 419.530.2065
Fax: 419.530.7737

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Departmental News:



 2013 Publications

  • Angel CA1, Lutz L, Yang X, Rodriguez A, Adair A, Zhang Y, Leisner SM, Nelson RS, Schoelz JE. (2013). The P6 protein of Cauliflower mosaic virus interacts with CHUP1, a plant protein which moves chloroplasts on actin microfilaments. Virology. 2013 Sep 1;443(2):363-74. doi: 10.1016/j.virol.2013.05.028. Epub 2013 Jun 12.

  • Avidor-Reiss T. Gopalakrishnan J. Cell Cycle Regulation of the Centrosome and Cilium. Drug Discovery Today: Disease Mechanisms 2013

  • Basiri, ML. Blachon S.  Chim, YCF, and Avidor-Reiss T. Imaging Centrosomes in Fly Testes.  The Journal of Visualized Experiments 2013 Sep 20;(79):e50938. doi: 10.3791/50938.

  • Chadee DN. Involvement of mixed lineage kinase 3 in cancer. Can J Physiol Pharmacol. 2013 Apr;91(4):268-74. doi: 10.1139/cjpp-2012-0258. Epub 2012 Dec 19. Review.

  • Du P, Tang F, Qiu Y, Dong F. GFI1 is repressed by p53 and inhibits DNA damage-induced apoptosis. PLoS One. 2013 Sep 4;8(9):e73542. doi: 10.1371/journal.pone.0073542. eCollection 2013.

  • Gao S, Hsieh CL, Bhansali M, Kannan A, Shemshedini L.  A peptide against soluble guanylyl cyclase α1: a new approach to treating prostate cancer. PLoS One. 2013 May 27;8(5):e64189. doi: 10.1371/journal.pone.0064189. Print 2013.

  • Gao S, Hsieh CL, Zhou J, Shemshedini L. Zinc Finger 280B regulates sGCα1 and p53 in prostate cancer cells. PLoS One. 2013 Nov 13;8(11):e78766. doi: 10.1371/journal.pone.0078766. eCollection 2013.

  • Hammer A, Rider L, Oladimeji P, Cook L, Li Q, Mattingly RR, Diakonova M. (2013). Tyrosyl phosphorylated PAK1 regulates breast cancer cell motility in response to prolactin through filamin A. Mol Endocrinol. 2013 Mar;27(3):455-65. doi: 10.1210/me.2012-1291. Epub 2013 Jan 22.

  • Hapiak V, Summers P, Ortega A, Law WJ, Stein A, Komuniecki R. (2013). Neuropeptides amplify and focus the monoaminergic inhibition of nociception in Caenorhabditis elegans. J Neurosci. 2013 Aug 28;33(35):14107-16. doi: 10.1523/JNEUROSCI.1324-13.

  • Hapiak V, Summers P, Ortega A, Law WJ, Stein A, Komuniecki R. Neuropeptides amplify and focus the monoaminergic inhibition of nociception in Caenorhabditis elegans. J Neurosci. 2013 Aug 28;33(35):14107-16. doi: 10.1523/JNEUROSCI.1324-13.2013.

  • Ma, J. , Zhang, L., *Tipton, A.R, Wu, J., Messmer-Blust, A., Philbrick, M., Qi, Y., Liu, S.T., Liu, H., Li, J. and Guo, S. (2013) Structural and Functional Analysis of the Related Transcriptional Enhancer Factor-1 (RTEF-1) and Nuclear Factor Kappa B (NF-κB) Interaction. American Journal of Physiology-Heart and Circulatory Physiology. 2013 Nov 8. [Epub ahead of print]. PMID: 24213609

  • Pei Du, Fangqiang Tang, Yaling Qiu, and Fan Dong*. (2013). GFI1 Is Repressed by p53 and Inhibits DNA Damage-Induced Apoptosis. PLoS One. 2013; 8(9): e73542.

  • Pierce LR1, Willey JC, Crawford EL, Palsule VV, Leaman DW, Faisal M, Kim RK, Shepherd BS, Stanoszek LM, Stepien CA. (2013).  A new StaRT-PCR approach to detect and quantify fish Viral Hemorrhagic Septicemia virus (VHSv): enhanced quality control with internal standards. J Virol Methods. 2013 Apr;189(1):129-42. doi: 10.1016/j.jviromet.2013.01.006. Epub 2013 Jan 30.

  • Qu C, Dwyer T, Shao Q, Yang T, Huang H, and Liu G (2013). Direct Binding of TUBB3 with DCC Couples Netrin-1 Signaling to Intracellular Microtubule Dynamics in Axon Outgrowth and Guidance. Journal of Cell Science 126 (14): 3070-3081. (Selected in In This Issue)       

  • Qu C, Li W, Shao Q, Dwyer T, Huang H, Yang T, and Liu G (2013). c-Jun N-Terminal Kinase 1 (JNK1) Is Required for Coordination of Netrin Signaling in Axon Guidance. Journal of Biological Chemistry 288 (3): 1883–1895.            

  • Rider L, Oladimeji P, Diakonova M. (2013). PAK1 regulates breast cancer cell invasion through secretion of matrix metalloproteinases in response to prolactin and three-dimensional collagen IV. Mol Endocrinol. 2013 Jul;27(7):1048-64. doi: 10.1210/me.2012-1322. Epub 2013 Jun 6.

  • Rossig C, Reinbothe C, Gray J, Valdes O, von Wettstein D, Reinbothe S. (2014). New functions of the chloroplast Preprotein and Amino acid Transporter (PRAT) family members in protein import. Plant Signal Behav. Jan 29;9(1). pii: e27693. [Epub ahead of print] Review.

  • Tipton AR, Ji W, Sturt-Gillespie B, Bekier ME 2nd, Wang K, Taylor WR, Liu ST. Monopolar spindle 1 (MPS1) kinase promotes production of closed MAD2 (C-MAD2) conformer and assembly of the mitotic checkpoint complex. J Biol Chem. 2013 Dec 6;288(49):35149-58. doi: 10.1074/jbc.M113.522375. Epub 2013 Oct 22.

  • Zhang X, Tao Y, Wang J, Garcia-Mata R, Markovic-Plese S. 2013. Simvastatin inhibits secretion of Th17-polarizing cytokines and antigen presentation by DCs in patients with relapsing remitting MS. Eur J Immunol. 43, 281-289.

2014 Publications:

  • Blachon S, Khire A, and Avidor-Reiss T.  The Origin of the Second Centriole of the Zygote.  Genetics. Early Online February 13, 2014, doi:10.1534/genetics.113.160523

  • C. Guilluy, L. Osborne, L. Van Landeghem, L. Sharek, R. Superfine, R. Garcia-Mata, and Keith Burridge. 2014. Isolated nuclei adapt to force and reveal a mechanotransduction pathway within the nucleus, Nature Cell Biology (Mar 9. doi: 10.1038/ncb2927. [Epub ahead of print])

  • Liu, S.T. (2014) Kinetochore Strucuture, Function and Evolution (version 2.0), In: Encyclopedia of Life Sciences (ELS).John Wiley & Sons, Ltd. Chichester. invited review.

  • Richard Komuniecki, Vera Hapiak, Ph. D.; Gareth Harris, Ph. D.; Bruce Bamber, Ph. D. (2014) Context-dependent modulation configures interact sensory-mediated microcircuits in C. elegans

  • Rossig C, Reinbothe C, Gray J, Valdes O, von Wettstein D, Reinbothe S. New functions of the chloroplast Preprotein and Amino acid Transporter (PRAT) family members in protein import. Plant Signal Behav. 2014 Jan 29;9(1). pii: e27693. [Epub ahead of print] Review.

  • S.M. Goicoechea , R. Garcia-Mata, J. Staub, A. Valdivia, L. Sharek, C.A. McCulloch, R. Hwang, R. Urrutia, J.J. Yeh, H.J, Kim, and C. Otey. 2014. Palladin promotes invasion of pancreatic cancer cells by enhancing invadopodia formation in cancer-associated fibroblasts, Oncogene  (6;33(10):1265-73)

  • S.M. Goicoechea , S. Awadia and R. Garcia-Mata. 2014. I'm coming to GEF you. Regulation of RhoGEFs during cell migration. Cell Adhesion & Migration (in press)

  • RNase L interacts with Filamin A to regulate actin dynamics and barrier function for viral entry. Malathi K*, Siddiqui MA, Dayal S, Naji M, Ezelle HJ, Zeng C, Zhou A, Hassel BA. MBio. 2014 Oct 28;5(6):e02012. doi: 10.1128/mBio.02012-14.PMID:25352621(*Communicating  author).

  • RNase L contributes to experimentally induced type 1 diabetes onset in mice. Zeng C, Yi X, Zipris D, Liu H, Zhang L, Zheng Q, Malathi K, Jin G, Zhou A. J Endocrinol. 2014 Dec;223(3):277-87. doi: 10.1530/JOE-14-0509. Epub 2014 Oct 6. PMID:25287058

  • Epigallocatechin-3-gallate suppresses proinflammatory cytokines and chemokines induced by Toll-like receptor 9 agonists in prostate cancer cells. Mukherjee S, Siddiqui MA, Dayal S, Ayoub YZ, Malathi K*.  J Inflamm Res. Jun 17;7:89-101, 2014. (*Communicating  author).

    2015 Publications:

  • RNase L cleavage products promote switch from autophagy to apoptosis by caspase-mediated cleavage of Beclin-1. Siddiqui, MA, Mukherhee, S, Manivannan, P and Malathi K* Int. J. Mol. Sci. 2015, 16, 17611-17636; doi:10.3390/ijms160817611.  (*Communicating  author).

Other Recent Publications from the Department of Biological Sciences

Biological Sciences Researchers In the News
Interdisciplinary research team swimming together to track fish killer - Dr. Douglas Leaman
Cellular research yields body of knowledge to fight disease, disorders - Dr. Tomer Avidor-Reiss


Recent External Grant Awards in Biological Sciences:

Faculty   Member




Tomer   Avidor-Reiss

Centriole Inheritance During Reproduction

National Science Foundation


Tomer   Avidor-Reiss

The Mechanism of Pericentriolar Material Assembly During Centrosome Biogenesis

National Institutes of Health


Bruce   Bamber

Electrophysiology of C. elegans Behavioral Circuitry

Whitehall Foundation


Deborah   Chadee

MLK4 Regulation of MAPK Signaling

National Institutes of Health


Fan   Dong

ELANE and CSF3R Mutations in Severe Congenital Neutropenia

National   Institutes of Health


Rafael   Garcia-Mata

Molecular Mechanisms of Invadopodia Formation in Breast Cancer Cells

Ohio Cancer Research Associates


John Gray

GEPR: Systems Approaches to Identify Gene Regulatory Networks in the Grasses

Ohio State University/NSF


Richard   Komuniecki

Chimeric Nematode Models for Anthelmintic Discovery

Bill and Melinda Gates Foundation


Scott   Leisner

Examination of Factors Influencing Virus Disease in Floriculture Crops

U.S. Department of Agriculture


Anthony   Quinn

Chemotherapeutic Regulation of Autoimmunity Without Overt Cytotoxicity

American   Heart Association - Great Rivers Affiliate


William   Taylor

Regulation of Sororin Function by Mitotic Phosphorylation

National Institutes of Health


Richard   Komuniecki

Locomotion in Parasitic Nematodes National Institutes of Health


Douglas Leaman

Gene Diversity of the VHS Fish Virus: Evolution of Cellular Immune Response and Pathogenesis National Science Foundation


Guofa Liu

 Coming Soon  Coming Soon  

Song-Tao Liu

TRIP13 AAA-ATPase overexpression in chromosomal instability and breast cancer National Institutes of Health  $1,224,000.00


Other External Grant Awards in the Department of Biological Sciences


Recent Accolades for Department Faculty

  • Anthony Quinn:      Outstanding Teaching Award  2013
  • Song-Tao Liu:        Tenure and Promotion 2013
  • Guofa Liu:              Tenure and Promotion 2014         
  • Brenda Leady:       Promoted to Lecturer 2013
  • John Arnold:          Promoted to Lab Coordinator 2013
  • Brianne Sturt:        Hired as Lab Technologist 2013
  • Donna Braswell:    College of Natural Science and Mathematics Outstanding Staff Award


Recent Graduates from the Departmental graduate degree programs:

  • Veronica Lommler:     M.S.  Biology
  • Hapiak, Vera:            Ph.D. Biology
  • Abi Saab, Widian:      Ph.D. Biology
  • Gao, Shuai:               Ph.D. Biology
  • Du, Pei:                     Ph.D. Biology
  • Lutz, Lindy:               Ph.D. Biology
  • Yuan Wenjue            M.S.   Biology
  • Hang Zhang              M.S.   Biology
  • Lindsay Schreiner     Ph.D.  Biology


Past Graduates from the Departmental graduate degree programs      

 2015 Symposium Winners

Left to Right Names of the Winner: left to right are Yusef Barudi (2nd Place), Alisha Sangal (1st Place) and Shazli Khan (3rd Place)

Department of Biological Sciences
Awards 2015

Undergraduate Research Symposium      
1st Place      Alysha Sangal
2nd Place     Yusef Barudi
3rd Place      Shazli Khan
Outstanding Student     Sandy Baghdy
High GPA      Amy Custer
High GPA      Tess Gao
Outstanding Undergraduate TA     Christian Siebenaler
Outstanding Peer Mentor     Meerna Naji
Wolfe Scholarship     Andrea Tsatalis
Biology Merit (3)     Isaiah Ingram
Batool Mehdi
Karlyn Waldeck
Hartman Scholarship     Ashley LaFontaine
Balch Fellowship     Karlyn Waldeck

 Please see the news archive page for past events.




Last Updated: 9/13/15