The University of Toledo | Protecting Health

Protecting Health

UToledo is Developing Solutions to Prevent and Treat Global Health Challenges
UTMC physician administering shot to patient

With reports projecting antimicrobial resistance to cost millions in lives and economic damages worldwide by 2050, researchers at The University of Toledo have a renewed urgency to develop vaccines and treatments to protect our public health.

Steven Sucheck, Ph.D., and Katherine Wall, Ph.D., are collaborating on new prevention methods that don't rely on dead or weakened pathogens. Supported by a $2.3 million grant from the National Institutes of Health, the chemists are creating a synthetic vaccine against Pseudomonas aeruginosa, an antibiotic-resistant bacterial infection that can be deadly for people with compromised immune systems and conditions such as cystic fibrosis.

Photo Dr. Steven Sucheck and Dr. Katherine Wall collaborating

Lyme disease affects more than 300,000 Americans annually, and Mark Wooten, Ph.D. has dedicated his career to developing more effective therapies to prevent and treat the illness that is spread by ticks. He created advanced microscopy methods to study how the disease progresses in real-time.

Dr. Mark Wooten in a lab

Tuberculosis is the world's leading cause of death from infectious disease. Dr. Sucheck's expertise also includes working to create a new, more effective drug to treat the illness that is becoming increasingly drug-resistant. His research is supported by a $2.1 million grant from the National Institutes of Health.

Headshot of Dr. Sucheck

Heather Conti, Ph.D., studies the body's immune response to the fungal infection called oral candidiasis, more commonly known as thrush. Her work looks at the role blood platelets play in the body's natural defense against oral candidiasis in hopes of developing therapeutics that can both kill the fungi and boost the immune response.

Headshot of Dr. Heather Conti

Cheryl McCullumsmith, M.D., Ph.D., is investigating the use of ketamine as a novel treatment for suicide ideation. Ketamine is traditionally used as an anesthetic agent, but her research is showing promise for treating suicidal individuals in crisis.

Headshot of Dr. Cheryl McCullumsmith

Incidents of sepsis, a life-threatening condition caused when the body's response to infection damages its own tissues and organs, have risen nearly 30% in the past decade. Kevin Pan, M.D., Ph.D., is exploring whether the drug rolipram - shown to be an effective antidepressant - could be a viable treatment.

Photo of Kevin Pan, M.D., Ph.D.

Learn More


More Features Like This:     Finding Cures     Providing Hope     Improving Care