Center for Hypertension and Personalized Medicine

CHRISTOPHER J. COOPER, M.D., F.A.C.C., F.A.C.P., F.A.H.A.

Executive Vice President for Clinical Affairsl
Professor and Dean of the College of Medicine & Life Sciences

Health Science Campus
Mulford Library Building
Second Floor - 213
Phone: 419.383.4243
Email: christopher.cooper@utoledo.edu

Education

1985 - B.A., Biology major, Philosophy minor, Wittenberg University, Springfield, Ohio
1988 - M.D., Medicine, University of Cincinnati, College of Medicine, Cincinnati, Ohio

Post Graduate Training, Residencies and Fellowships

1988-1989: Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, Internship
1989-1991: Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, Residency
1991-1994: Brigham and Women’s Hospital, and Harvard Medical School, Boston, Massachusetts, Cardiology, Fellowship
1992:Harvard School of Public Health, Clinical Effectiveness Course: Intensive 2 month course in biostatistics, epidemiology, decision analysis, and health policy research

Employment

1994 - 1998: Assistant Professor of Medicine, Medical College of Ohio, Division of Cardiology, Department of Medicine, Toledo, OH

1998 - 2002: Associate Professor of Medicine, Medical College of Ohio, Division of Cardiology, Department of Medicine, Toledo, OH

1999 - 2006: Director, Cardiovascular Research, Medical University of Ohio (formerly Medical College of Ohio),  Toledo, OH

2002 – 2012: Chief, Division of Cardiovascular Medicine, The University of Toledo - Health Science Campus (formerly Medical University of Ohio), Toledo, OH

2002 – Present: Professor of Medicine, The University of Toledo - Health Science Campus, Division of Cardiovascular Medicine, Department of Medicine, Toledo, OH

2002 - Present: Director, UT Clinical Coordinating Center, The University of Toledo - Health Science Campus, Toledo, OH

2005 – 2008: Director, Cardiovascular Interventional Fellowship, The University of Toledo - Health Science Campus, Toledo, OH

2007 – 2008: Director, Cardiovascular Medicine Fellowship, The University of Toledo - Health Science Campus, Toledo, OH

2008 - 2011: Director, Heart and Vascular Center, University of Toledo Medical Center, Toledo, OH

2012 – 2013: Interim Chairman, Department of Medicine, The University of Toledo, Toledo, OH

4/1/13–8/17/14: Chairman, Department of Medicine, The University of Toledo, Toledo, OH

7/1/13-8/17/14: Vice President, University of Toledo Physicians

7/1/14-8/17/14: Vice Chief of Staff, University of Toledo Medical Center, Toledo, OH

8/18/14-Present: Dean, College of Medicine, The University of Toledo, Toledo, OH     

8/18/14-Present: Executive Vice President for Clinical Affairs, The University of Toledo, Toledo, OH

8/18/14-Present: CEO, University of Toledo Physicians

Certifications and Licensures

  • Internal Medicine, The American Board of Internal Medicine, September 1991, #137285, recertification 2004, 2014, exp. 2024
  • Cardiovascular Disease, The American Board of Internal Medicine, January 1995, #137285, recertification 2004, 2014, exp. 2024
  • Interventional Cardiology, The American Board of Internal Medicine, January 2000, #137285, recertification 2009, exp 2019
  • Ohio Medical License #66906, exp. 04/01/2017

Awards and Commendations

Mortar Board, Wittenberg University, Springfield, Ohio, 1983
Award for Highest Course Honors, University of Cincinnati, Department of Physiology, 1985
Magna cum laude graduate, with Honors in Major, Biology, Wittenberg University, 1985
Academic Scholarship, University of Cincinnati, 1985-1986
Pharmacology Award, Merrell Dow Research Institute, 1986
Academic Scholarship, University of Cincinnati, 1986-1987
UFCW Scholarship, 1986-1987
Third year Alpha Omega Alpha, University of Cincinnati, 1987
Academic Scholarship, University of Cincinnati, 1987-1988
Valedictorian, University of Cincinnati, College of Medicine, 1988
Finalist, Samuel A. Levine Young Clinical Investigator Awards, American Heart Association, Council on Clinical Cardiology, 69th Scientific Sessions, New Orleans, Louisiana, 1996
"Best Doctors in America" Award, Issued by: Best Doctors in America, Midwest, 2002
Elected Fellow, American Heart Association, Council of High Blood Pressure Research, 2004
“America’s Top Doctors” Award, Issued by: Castle Connolly, 2006
“America’s Top Doctors” Award, Issued by: Castle Connolly, 2007
College of Medicine Award for Excellence in Clinical Research. University of Toledo, 2008
“America’s Top Doctors”. Award, issued by Castle Connolly, 2008
“America’s Top Doctors”. Award, issued by Castle Connolly, 2009
“Best Doctor’s in America: Award, Issued by Best Doctors, LLC. 2010
“America’s Top Doctors”. Award, issued by Castle Connolly, 2010
“Best Doctor’s in America: Award, Issued by Best Doctors, LLC 2011
“America’s Top Doctors”. Award, issued by Castle Connolly, 2011
“America’s Top Doctors”.  Award, issued by US News and World Report, 2012
“Best Doctors in America” Award, issued by Best Doctors, LLC. 2013
“Best Doctors in America” Award, issued by Best Doctors, LLC, 2014
“America’s Top Doctors” Award, Issued by Castle Connolly, 2014
“America’s Top Doctors” Award, Issued by Castle Connolly, 2015

Major Research Interests

Renovascular Hypertension; Renal insufficiency and Cardiovascular Events; Cell therapy for vascular diseases

Publications

Publications by Dr. Cooper since inception of CHPM in January 1st, 2012:

1) Moza A, Taleb M, Cooper CJ, Burket MW.  Percutaneous coronary intervention through unintentional sheath placement in the inferior epigastric artery.  Cardiovasc Interv Ther. 2013 Jan;28(1):98-100.  Epub 2012 Aug 9.  PMID: 22875748.

2) Moza A, Sheikh M, Rock-Willoughby J, Cooper C, Kanjwal Y.  Idiopathic hypereosinophilic syndrome presenting with cardiac tamponade. Heart Lung. 2012. PMID: 22770997.

3) Liu C, Bai Y, Chen Y, Wang Y, Sottejeau Y, Liu L, Li X, Lingrel JB, Malhotra D, Cooper CJ, Shapiro JI, Xie ZJ, Tian J. Reduction of Na/K-ATPase potentiates marinobufagenin-induced cardiac dysfunction and myocyte apoptosis. J Biol Chem. 2012 May 11;287(20):16390-8. doi: 10.1074/jbc.M111.304451. Epub 2012 Mar 27. PMID: 22451662

4) Taleb MM, Sheikh MA, Cooper CJ, Tinkel JL. Multiple coronary to pulmonary artery fistulas: a case report and review of the literature. Cardiovasc Interv Ther. 2012 May;27(2):127-30. Epub 2012 Feb 14.  PMID: 22623009.

5) Sheikh M, Bruhl SR, Omer S, Schwaan T, Grubb B, Cooper C, Kanjwal Y. Transmyocardial voyage of a temporary epicardial lead: an unusual long-term complication. Pacing Clin Electrophysiol. 2012 Jul;35(7):e185-6. doi: 10.1111/j.1540-8159.2011.03112.x. Epub 2011 Apr 28. PMID: 21535035.

6) Haller S, Kalra PA, Ritchie JP, Chrysochou T, Brewster P, He W, Yu H, Shapiro JI, Cooper CJ. Effect of CD40 and sCD40L on Renal Function and Survival in Patients with Renal Artery Stenosis. Hypertension. 2013 Apr;61(4):9894-900.  Epub 2013 Feb 11.  PMID: 23399713.

7) Klochan SA, Taleb M, Hoover MJ, Mauro VF, Anandan V, Willey J, Cooper CJ. Illicit narcotic injection masquerading as acute pulmonary embolism. Vascular Medicine. 2013 Apr; 18(2):92-4.  Epub 2013 Mar 14.  PMID: 23493623.

8) Anderson W, Eshghinejad A, Azadegan R, Cooper CJ, Elahinia M. A variable stiffness transverse mode shape memory alloy actuator as a minimally invasive organ positioner. Accepted April 2013 for publication in European Physical Journal – Special TOPICS.

9) Cooper CJ, Murphy TP, Cutlip DE, Jamerson K, Henrich, W.  Stenting and Medical Therapy for Atherosclerotic Renal-Artery Stenosis.  N Engl J Med.  2013 Nov 18. (Epub ahead of print) PMID: 24245566.

10) Haller ST, Evans KL, Folt DA, Drummond CA, Cooper CJ. Mechanisms and treatments for renal artery stenosis. Discov Med. 2013 Dec;16(90):255-60. Review. PMID: 24333404

11) Murphy TP, Cooper CJ, Cutlip DE, Matsumoto A, Jamerson K, Rundback J, Rosenfeld KA, Henrich W, Shapiro J, Massaro J, Yen CH, Burtch H, Thum C, Redi D, Dworkin L. Roll-in experience from the cardiovascular outcomes with renal atherosclerotic lesions (CORAL) study. J Vasc Interv Radiol 2014 Apr;25(4):511-20 DOI: 10.1016/J.JVIR2013.09.018.EPUB 2013 Dec 8.

12) Khan AR, Sheikh M, Kaw D. Cooper CJ, Khouri S. Prevalence and factors associated with left ventricular remodeling in renal artery stenosis. J Am Soc Hypert. 2014 Apr;8(4):254-61 DOI:10.1016/J.JASH.2014.01.008 EPUB 2014 Jan 27 (EPUB ahead of print).

 

13) Colyer WR, Cooper CJ.  The Future of Renal Artery Stenting.  Accepted for publication in Interventional Cardiology April 2014.

14) Drummond CA, Sayed M, Evans KL, Shi H, Wang X, Haller ST, Liu J, Cooper CJ, Xie Z, Shapiro JI, Tian J. Reduction of Na/K-ATPase affects cardiac remodeling and increases c-kit cell abundance in partial nephrectomized mice. Am J Physiol Heart Circ Physiol. 2014 Jun 15;306(12):H1631-43. doi: 10.1152/ajpheart.00102.2014. Epub 2014 Apr 18. PMID: 24748592

15) Murphy TP, Dworkin LD, Cooper CJStenting for renal-artery stenosis. N Engl J Med. 2014 May 8;370(19):1854-5. doi: 10.1056/NEJMc1402687. No abstract available. PMID: 24806166

16) Khan AR, Sheikh MA, Kaw D, Cooper CJ, Khouri SJ.Rebuttal: Relationship of left ventricular hypertrophy, age, and renal artery stenosis. J Am Soc Hypertens. 2014 May;8(5):361. doi: 10.1016/j.jash.2014.02.006. Epub 2014 Feb 22. No abstract available. PMID: 24726948

17) Evans, KL, Tuttle, KR, Folt, DA, Dawson, T, Haller, ST, Brewster, PS, He, W, Jamerson, K, Dworkin, L, Cutlip, D, Murphy, TP, Reid, D, D’Agostino, Sr., RB,  Henrich, W, Cooper, CJ. Use of Renin-Angiotensin Inhibitors In People with Renal-Artery Stenosis. Clin J Am Soc Nephrol. 2014 Jul;9(7):1199-206. Doi:10.2215/cjn.

18) Moza A, Moukarbel GV, Cooper CJ, Bhat PK. Myocardial ischemia in a patient with peripheral vascular disease, an arteriovenous fistula, and patent coronary artery bypass grafts.         Cardiovasc Interv Ther. 2015 Jul;30(3):279-82. doi: 10.1007/s12928-014-0284-2. Epub 2014 Jul 16. PMID: 25027049

19) Hendricks NJ, Matsumoto AH, Angle JF, Baheti A, Sabri SS, Park AW, Stone JR, Patrie JT, Dworkin L, Cooper CJ, Murphy TP, Cutlip DE. Is fibromuscular dysplasia underdiagnosed? A comparison of the prevalence of FMD seen in CORAL trial participants versus a single institution population of renal donor candidates. Vasc Med. 2014 Oct;19(5):363-7. doi: 10.1177/1358863X14544715. Epub 2014 Jul 31.

20) Chowdhury MA, Moza A, Siddiqui NS, Bonnell M, Cooper CJEmergent echocardiography and extracorporeal membrane oxygenation: Lifesaving in massive pulmonary embolism. Heart Lung. 2015 Jul-Aug;44(4):344-6. doi: 10.1016/j.hrtlng.2015.05.001. Epub 2015 May 27. PMID: 26025763

21) Folt DA, Evans KL, Brahmandam S, He W, Brewster PS, Yu S, Murphy TP, Cutlip DE, Dworkin LD, Jamerson K, Henrich W, Kalra PA, Tobe S, Thomson K, Holden A, Rayner BL, Grinfeld L, Haller ST, Cooper CJRegional and physician specialty-associated variations in the medical management of atherosclerotic renal-artery stenosis. J Am Soc Hypertens. 2015 Jun;9(6):443-52. doi: 10.1016/j.jash.2015.03.007. Epub 2015 Mar 28.

22) Murphy TP, Cooper CJ, Matsumoto AH, Cutlip DE, Pencina KM, Jamerson K, Tuttle KR, Shapiro JI, D'Agostino R, Massaro J, Henrich W, Dworkin LD. Renal Artery Stent Outcomes: Effect of Baseline Blood Pressure, Stenosis Severity, and Translesion Pressure Gradient. J Am Coll Cardiol. 2015 Dec 8;66(22):2487-94. doi: 10.1016/j.jacc.2015.09.073.

23) Drummond CA, Hill MC, Shi H, Fan X, Xie JX, Haller ST, Kennedy DJ, Liu J, Garrett MR, Xie Z, Cooper CJ, Shapiro JI, Tian J. Na/K-ATPase Signaling Regulates Collagen Synthesis Through microRNA-29b-3p in Cardiac Fibroblasts. Physiol Genomics. 2015 Dec 23:physiolgenomics.00116.2015. doi: 10.1152/physiolgenomics.00116.2015. [Epub ahead of print]

Last Updated: 8/9/17