Mahasin A. Osman, Msc. Ph.D. — Publications
Selected articles
Robinson TS, Osman MA. An Emerging Role for Sigma Receptor 1 in Personalized Treatment of Breast Cancer. Cancers (Basel). 2023 Jul 2;15(13):3464. doi: 10.3390/cancers15133464. PMID: 37444574; PMCID: PMC10340381.
Iyer VJ, Osman MA (2023). The Antipsychotic Drug Haldol Modulates IQGAP1-Signaling and Inhibits Cell Proliferation in Triple Negative Breast Cancer Cell Lines. MicroPubl Biol. 2023 May 5;2023:10.17912/micropub.biology.000823. doi: 10.17912/micropub.biology.000823. PMID: 37215640; PMCID: PMC10199339.
Iyer VJ, Osman MA (2023). Haldol Targets IQGAP1 Pathway and Promotes Novel Partner Interactions in Glioblastoma Cell Lines. MicroPubl Biol. 2023 May 8;2023:10.17912/micropub.biology.000822. doi: 10.17912/micropub.biology.000822. PMID: 37228393; PMCID: PMC10203884.
Osman M. A*., Antonisamy W. J, Yakirevich E. IQGAP1 control of centrosome function defines distinct variants of triple negative breast cancer. Oncotarget. 2020; 11: 2493-2511. Retrieved from https://www.oncotarget.com/article/27623/-- Front COVER PAPER
Emmanuel A. Tagoe, Gordon A. Awandare, Osbourne Quaye, Richard H. Asmah, Timothy N. Archampong, Mahasin A. Osman, and Charles A. Brown (2021). Helicobacter Pylori Variants with ABC-Type Tyrosine Phosphorylation Motif in Gastric Biopsies of Ghanaian Patients. BioMed Res. Interl 2021 6616059. https://www.hindawi.com/journals/bmri/2021/6616059/
Tanos, B. E., Perez Bay, A. E., Salvarezza, S., Vivanco, I., Mellinghoff, I., Osman, M., Sacks, D. B., Rodriguez-Boulan, E. IQGAP1 controls tight junction formation through differential regulation of claudin recruitment.Journal of cell science. 2015; 128 (5) : 853-862. Full Text PubMed
Slavica Tudzarova and Mahasin A. Osman The double trouble of metabolic diseases: the diabetes–cancer link. Molecular biology of the cell. 2015; 26 (18) : 3129-3139. Full Text PubMed
Osman MA, Sarkar FH, Rodriguez-Boulan E A molecular rheostat at the interface of cancer and diabetes.. Biochimica et biophysica acta. 2013; 1836 (1) : 166-76. Full Text PubMed
Osman MA, Bloom GS, Tagoe EA Helicobacter pylori-induced alteration of epithelial cell signaling and polarity: a possible mechanism of gastric carcinoma etiology and disparity.. Cytoskeleton (Hoboken, N.J.). 2013; 70 (7) : 349-59. Full Text PubMed
Wang, J-B, Sonn, R., Tekletsadik, Y. K. Samorodnitsky, D. and Osman, M. A. (2009). IQGAP1 regulates cell proliferation through a novel CDC42-mTOR pathway. J Cell Sci; 122. p. 2024-2033. PMCID: PMC2723156.http://jcs.biologists.org/cgi/content/full/122/12/e1205?etoc highlighted editorially and on the cover
Rittmeyer, E. N. Daniel, S. Hsu, S. C., and Osman, M. A. (2008). A dual role for IQGAP1 in regulating exocytosis. J Cell Sci; 121, 391-408 (http://jcs.biologists.org/cgi/content/full/121/3/e303?etoc). Highlighted editorially and on the cover. PMID: 18216334.
Osman M An emerging role for IQGAP1 in regulating protein traffic..TheScientificWorldJournal. 2010; 10 : 944-53. Full Text PubMed
Books
Mahasin A. Osman Regulation of Cytoskeleton Dynamics in Health and Disease: role of molecular switches and rheostats. 2015; : 11-62. Full Text
Abstracts
Osman MA Role of Signal Dynamics in the Link Between Type 2 Diabetes and Cancer. . Journal of the Pancreas. 2014; 15 (5) : 530. More Info