Department of Pharmacology : Dr. Caren L. Steinmiller

Caren L. Steiniller
Visiting Assistant Professor
Department of Pharmacology

WO 2243
419.530.1912

Institutions/Degrees

Research Interests

• Behavioral Neuroscience of Opioid Addiction and Treatment
• Behavioral Neuroscience of Poly-Substance Abuse/Addiction and Treatment
• Behavioral Neuroscience of Alcohol Abuse/Addiction and Treatment
• Behavioral Economic Analysis of Drug Abuse and its Consequences

Publications

Steinmiller CL, Greenwald MK (in preparation) Correlates of recent alcohol use in heroin-dependent research volunteers.

Young AM, Steinmiller CL, Irtenkauf S, Childrey A, Walker B, Muhammad E, Bowen SE, Evola M (in preparation) Apparent potency of opioid antagonists varies as a function of behavioral endpoint.

Greenwald MK, Steinmiller CL (in preparation) Behavioral economic analysis of opioid consumption in heroin-dependent individuals: effects of alternative reinforcer magnitude and post-session drug supply.

Suto N, Steinmiller CL, Pham CT, Baker LK, Vezina P (in preparation) Neuroadaptation underlying compulsive drug-seeking. 

Steinmiller CL, Young AM (2008) Pharmacological selectivity of CTAP in the warm water tail-withdrawal antinociception assay in rats. Psychopharmacology 195(4):497-507

Steinmiller CL, Greenwald MK (2007) Factors associated with non-medical opioid abuse among heroin-dependent research volunteers. Experimental and Clinical Psychopharmacology 15(5):492-500.

 Tanabe, LM, Suto N, Creekmore E, Steinmiller CL, Vezina P  (2004) Blockade of D2 dopamine receptors in the VTA produces a long-lasting enhancement of the locomotor activating effects of amphetamine.  Behavioral Pharmacology 15 (5-6), 387-395.

Steinmiller, CL, Maisonneuve IM, Glick SD  (2003) Effects of dextromethorphan on dopamine release in the nucleus accumbens:  Interactions with morphine.  Pharmacology, Biochemistry, and Behavior.  74(4), 803-810.

Dimmock, JR, Puthcode RN, Tuchek J, Baker GB, Hinko CN, Steinmiller CL, Stables JP (1999)  Anticonvulsant activities of 4-(4’-Fluorophenoxy)-benzaldehyde semicarbazone.  Drug Development Research 46, 112-125.

Hinko, CN, Crider AM, Kleim MA, Steinmiller CL, Seo TH, Ho B, Venkatarangan P, El-Assadi AA, Chang H, Burns CM, Tietz EI, Andersen PH, Klitgaard H (1996) Anti-convulsant activity of novel derivatives of 2- and 3-piperidenecarboxylic acid in mice and rats.  Neuropharmacology, 35(12), 1721-1735.

Books and Chapters:

Greenwald MK, Steinmiller CL (2008) Imaging opioid receptors:  applications to substance use disorders.  In:  Dean R, Negus SS, Bilsky E (Eds.), Opioid Receptors and Antagonists: From Bench to Clinic.  New York: Humana Press.

Published Abstracts

Steinmiller CL, Moretti JA, Irtenkauf SM, Young AM.  (1997) Characterization of the antagonistic profile of CTAP using the warm water tail-withdrawal assay.  27^th Annual Meeting of the Society for Neuroscience. 

Steinmiller CL, Young AM  (1998)  Antagonist potency of CTAP, naloxone methiodide, and naltrexone in the warm water tail-withdrawal assay.  28^th Annual Meeting of the Society for Neuroscience. 

Bowen SE, Moretti JA, Steinmiller CL, Young AM (1998) Behavioral pharmacology of the highly potent and mu-selective opioid antagonist CTAP.  Problems of Drug Dependence 2002:  Proceeding of the 60^th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc.

Bowen SE, Steinmiller CL, Young AM  (1999)  Pharmacological characterization of sensitization to opioid antagonists.  Problems of Drug Dependence 2002:  Proceeding of the 61st Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc.

Young AM, Bowen SE, Steinmiller CL (2000)  Characterization of sensitization to opioid antagonists.  2000 Meeting for British Association for Psychopharmacology.

Young AM, Bowen SE, Steinmiller CL (2000)  Characterization of sensitization to opioid antagonists.  American Society for Pharmacology and Experimental Therapeutics.  Boston, MA.

Weber AA, Bowen SE, Steinmiller CL, Young AM  (2000)  Examination of the potency of naloxone methiodide following acute and chronic administration of morphine.  2000 Michigan Chapter, Society for Neuroscience.  Ypsilanti, MI.

Steinmiller CL, Bowen SE, Young AM (2000) CTAP precipitated withdrawal in morphine dependent rats.  Problems of Drug Dependence 2002:  Proceeding of the 62^th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc.

Bowen SE, Weber AA, Steinmiller CL, Young AM  (2000) Further characterization of sensitization to opioid antagonists. Problems of Drug Dependence 2002:  Proceeding of the 62^th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc.

Steinmiller CL, Maisonneuve IM, Glick SD (2001)  The effects of self-administered morphine on extracellular concentrations of dopamine, serotonin, and their metabolites in the nucleus accumbens of rats.  31^st Annual Meeting of the Society for Neuroscience. 

Maisonneuve IM, Steinmiller CL, Glick SD  (2001)  Dextromethorphan (DM) and 18-methoxycoronaridine (18MC):  Synergistic effects of morphine self-administration and possible mediation by nicotinic receptors. 31^st Annual Meeting of the Society for Neuroscience. 

Steinmiller CL, Kennedy RH, Baker LK, Suto N, Vezina P (2003) Evidence that previous exposure to amphetamine can sensitize AMPA-evoked dopamine overflow in the nucleus accumbens.  33^rd Annual Meeting of the Society for Neuroscience.

Steinmiller CL, Maisonneuve IM, Glick SD (2002) Effects of morphine on extracellular levels of dopamine in the basolateral amygdala.  32^nd Annual Meeting of the Society for Neuroscience.

Steinmiller CL, Maisonneuve IM, Glick SD (2002) Effects of dextromethorphan on dopamine release in the nucleus accumbens:  Interactions with acute and chronic morphine. Problems of Drug Dependence 2002:  Proceeding of the 64^th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc.

Glick SD, Maisonneuve IM, Steinmiller CL, Kitchen BA, Warner LM. (2002)  Antagonism of a3b4 nicotinic receptors as a strategy to reduce opioid, stimulant, and nicotine self-administration. Problems of Drug Dependence 2002:  Proceeding of the 64^th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc.

Steinmiller CL, Greenwald MK (2005) Gender differences in prescription and non-medical use of opioids, sedatives and stimulants among heroin dependent research volunteers.  Problems of Drug Dependence 2005: Proceedings of the 67th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc.         

Steinmiller CL, Greenwald MK (2006) Factors associated with recreational opioid use in heroin-dependent research volunteers. Problems of Drug Dependence 2006: Proceedings of the 68th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc.

Steinmiller CL, Greenwald MK (2007) Correlates of Recent Alcohol Use in Heroin-Dependent Research Volunteers. Problems of Drug Dependence 2007: Proceedings of the 69^th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc.

Roddy J, Steinmiller CL, Greenwald MK (2007) Heroin Purchasing is Income- and Price-Sensitive. Problems of Drug Dependence 2007: Proceedings of the 69^th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc.

Steinmiller CL, Greenwald M (2008) Opioid Abstinence Reinforcement Delays Heroin Lapse During Buprenorphine Dose Tapering.  Problems of Drug Dependence 2008:  Proceedings of the 70^th Annual Scientific Meeting, The College on Problems of Drug dependence, Inc.

Lundahl LH, Lockhart H, Steinmiller CL, Tancer M, Johanson CE (2008) Differences in Subjective and Physiological Response to Oral THC in Cannabis Dependent Humans.  Problems of Drug Dependence 2008: Proceedings of the 70^th Annual Scientific Meeting, The College on Problems of Drug Dependence, Inc.