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College of Pharmacy
Graduate Programs
Master of Science in Pharmaceutical Sciences


Degrees Offered
The Master of Science in pharmaceutical sciences degree is designed to prepare an individual for responsibilities in
professional practice, the pharmaceutical industry and scientific research beyond those possible with a baccalaureate.
Although a single degree is conferred, specialization is possible in that the curriculum is organized into three distinct
disciplines. Applicants must select the program of study (option) they wish to pursue.
The Master of Science in pharmaceutical sciences is granted to the student who satisfactorily completes a minimum of 30
semester hours of graduate credit with a 3.0 or better GPA. Of the 30 semester hours, a maximum of six semester hours
is granted for thesis research.

Admission Requirements
In general, a baccalaureate in the sciences is required for admission, although applicants possessing other bachelor’s
degrees will be considered if the latter represent adequate preparation. Certain options and graduate courses require
undergraduate preparation as prerequisites, and this preparation should be completed as soon as possible upon admission
to the Graduate School. The total time required for completion of the graduate program leading to the Master of Science in
pharmaceutical sciences degree will depend upon the preparation of the student entering the Graduate School. Normally
two years of study and research are required.
The admission requirements of the Graduate School of the University apply. The basic requirement is a 2.7 (on a 4.0
scale) GPA on all undergraduate work leading to the bachelor’s degree. Applicants having less than a 2.7 GPA on all
undergraduate work will be considered for admission if other criteria for estimation of potential success in graduate
studies are positive.
Each student must submit three copies of transcripts, one of which must be official and show all post-secondary academic
work and degrees granted, three letters of recommendation from college faculty members acquainted with the applicant’s
character and ability, and scores from the aptitude portion of the GRE.
International students are required to take the TOEFL, which will be given in their own country by the Educational
Testing Service.
Normally, acceptance will be decided by April 1 for admission during the following fall semester. The priority deadline
for completed applications is Jan 15. International students are encouraged to submit applications one month prior to the
stated deadline to allow for delays in international correspondence.
Curriculum and Options – M.S. Program in Pharmaceutical Science
The options available to graduate students are pharmacology/toxicology, administrative pharmacy and industrial
pharmacy.
Pharmacology/Toxicology option:
Undergraduate courses required (or their equivalents):
CHEM 3710 Physical Chemistry For The Biosciences I  ...................  3
CHEM 3720 Physical Chemistry For The Biosciences II ...................  3
MATH 1750 Calculus for the Life Sciences I  ...................................4
MATH 1760 Calculus for the Life Sciences II................................... 3
MBC 3310 Medicinal Chemistry I: Drug Action and Design .............. 3
MBC 3320 Medicinal Chemistry II: Drug Targeting  
   to Receptors  ........................................................................  3
MBC 4300 Medicinal Chemistry III: Chemotherapy and
   Immunotherapy  ...................................................................  3
PHCL 2600 Functional Anatomy and Pathophysiology I ................... 4
PHCL 2620 Functional Anatomy and Pathophysiology II  ................. 4
 
Graduate courses required:
BIOL 5610 Advanced Biostatistics or
PHCL 5140 Interpretation of Pharmaceutical Data  ........................ 2-4
PHCL 5700 Pharmacology I-Principles of Pharmacology,
   Autonomic Pharmacology and Non-Steroidal  
   Anti‑Inflammatory Agents and Related  
   Pharmacology ................................................................................ 3
PHCL 5720 Pharmacology II: Endocrine and CNS Pharmacology .............. 3
PHCL 5730 Toxicology I  ..................................................................... 3
PHCL 5760 Toxicokinetics ................................................................... 3
PHCL 5900 Drug Disposition ............................................................... 2
PHCL 6150 Advanced Pharmacokinetics or  ........................................... 2
PHCL 6600 Seminar in Pharmacology  .................................................. 1
PHCL 6700 Pharmacology III: CNS and Cardiovascular/
   Renal Pharmacology  ....................................................................... 3
PHCL 6720 Pharmacology IV: Chemotherapeutics  ................................. 3
PHCL 6900 M.S. Thesis Research in Pharmacology  ............................. 1-6
PHCL 6920 M.S. Thesis Research in Pharmacology  ............................. 1-6
 
Additional course work may be selected from the following:
CHEM 6310 Separation Methods  ...................................................... 2-4
MBC 5620 Biochemical Techniques  ................................................... 2
MBC 6190 Advanced Medicinal Chemistry  ......................................... 4
PHCL 5300 Selected Topics in Pharmacology  ..................................... 2
PHCL 5420 Advanced Neuroscience .................................................. 2
PHCL 5750 Toxicology II ................................................................. 3
PHCL 5760 Toxicokinetics ............................................................... 3
PHCL 6770 Toxicological Risk Assessment ........................................ 3
 
Administrative Pharmacy option:  
Undergraduate courses required  
(or their equivalents):
BUAD 2040 Financial Accounting Information.................................. 3
ECON 1200 Principles of Microeconomics ....................................... 3
PHPR 3510 Pharmaceutical Dimensions of Health Care System ......... 3
PHPR 4520 Pharmaceutical Management and Marketing................... 3
Required courses include (or their equivalents):
FINA 5310 Managerial Finance ........................................................ 3
MGMT 5110 Introduction to Management ......................................... 3
MKTG 5410 Marketing Systems ....................................................... 3
PHPR 6520 Analysis of the Pharmaceutical Environment ..................... 3
PHPR 6530 Research Methods in Pharmacy Practice ........................... 3
PHPR 6600 Seminar in Administrative Pharmacy ............................... 1
PHPR 6960 M. S. Thesis Research in Pharmacy ................................. 1-6
RESM 5110 Quantitative Methods I ................................................. 3
RESM 6120 Quantitative Methods II ................................................ 3
Additional course work may be selected from these (or their equivalents; others as
approved by adviser):
BANS 5210 Economics for Business Decisions .................................. 3
BANS 6520 Managerial Economics .................................................. 3
BLAW 5150 Dynamics of Legal Environment of Business .................... 3
FINA 6130 Managerial Finance ....................................................... 3
INFS 6460 Management Information Systems .................................. 3
OPMT 5520 Analysis of Manufacturing & Service Systems .................. 3
ORGD 6170 The Individual and the Organization .............................. 3
ORGD 6590 Organization Theory and Design ................................... 3
PHPR 5990 Problems in Pharmacy Practice ...................................... 1-6
PHPR 6550 Management Topics for Clinical Practice .......................... 2
PHPR 6810 Hospital Pharmacy Administration .................................. 3
PHPR 6820 Selected Topics in Hospital Pharmacy  ............................ 3
PHPR 6830 Advanced Community Pharmacy Administration ............... 3
PHPR 6840 Selected Topics in Community Pharmacy ......................... 3
Industrial Pharmacy option:  
Undergraduate courses required:  
Courses will be evaluated for students with a B.S. in pharmacy, Pharm.D. or B.S.P.S. degree.
MBC 3550 Physiological Chemistry I: Structure and Function
   of Biological Macromolecules ...................................................... 3
MBC 3560 Physiological Chemistry II: Chemical Regulation
   of Cells and Organisms .............................................................. 3
PHPR 3070 Pharmaceutics and Pharmaceutical Technology I and  
PHPR 3080 Pharmaceutics and Pharmaceutical Technology II   
  or
CHEM 3710 Physical Chemistry for the Biosciences I and  
CHEM 3720 Physical Chemistry for the Biosciences II and
CHEM 3730 Physical Chemistry I ..................................................... 8-9
PHPR 4520 Pharmaceutical Management and Marketing ..................... 3
PHPR 4550 Analysis of the Pharmaceutical Environment...................... 3
Graduate required courses:  
CHEM 6300 Advanced Analytical Chemistry ....................................... 2-4
CHEM 6310 Separation Methods ...................................................... 2-4
EEES 5710 Advanced Biostatistics ................................................... 4
PHCL 6150 Advanced Pharmacokinetics ........................................... 2
PHPR 5690 Dosage Form Design ..................................................... 3
PHPR 5700 Equilibrium Phenomenon ............................................... 2
PHPR 5720 Pharmaceutical Rate Processes........................................ 3
PHPR 6600 Seminar in Administrative Pharmacy ............................... 1
PHPR 6850 Product Development .................................................... 3
Additional course work may be selected from the following:  
CHEM 6320 Characterization of Condensed Phases and Surfaces ... 2-4
CHEM 6330 Spectroscopic Methods and Analysis of Spectra .......... 2-4
CHEM 6720 Physical Chemistry of Material Transformations .......... 2-4
CHEM 6810 Materials Science I ................................................ 4
CHEM 6820 Materials Science II................................................ 4
CHEM 6980 Special Topics in Chemistry .....................................2-4
PHCL 5760 Toxicokinetics ........................................................ 3
PHPR 5680 Parenteral Manufacturing ........................................ 2
PHPR 5710 Selected Topics in Pharmaceutical Technology ............ 2-4
PHPR 5990 Problems in Pharmacy Practice ................................ 1-6
PHPR 6530 Research Methods in Pharmacy Practice .................... 3
PHPR 6610 Seminar I ............................................................. 1
PHPR 6960 M.S. Thesis Research in Pharmacy ........................... 1-6
 
Applicants for the administrative pharmacy and industrial pharmacy options who possess a B.S. in pharmacy, Pharm.D.
or bachelor of science in pharmaceutical sciences degree from an ACPE-accredited institution will be given preference
for admission into those options. International applicants must have earned pharmacy degrees from their home
institutions.

Master of Science in Medicinal Chemistry
Admission Requirements
Satisfactory completion of a bachelor’s degree in chemistry, biology, pharmacy or a related discipline is required. It is
assumed the undergraduate training will include differential and integral calculus, college physics, a one-year course in
general and inorganic chemistry including a laboratory, a one-year course in organic chemistry including a laboratory,
and training in analytical chemistry. An undergraduate course in physical chemistry is recommended.   
 
The admission requirements of the Graduate School of the University apply.
Degree Requirements
Master’s students need to complete the following courses as partial fulfillment of their requirement for an M.S.
degree:
MBC 5100 Research Practices in Medicinal Chemistry ....................... 1
MBC 5620 Biochemical Techniques ................................................ 2
MBC 5900 Medicinal Chemistry Seminar (4 hours required) .............. 1
MBC 6190 Advanced Medicinal Chemistry ...................................... 4
MBC 6200 Biomedicinal Chemistry ................................................ 4
MBC 6550 Biochemistry ............................................................... 4
MBC 6960 M.S. Thesis Research in  
   Medicinal Chemistry (6 hours required)...................................... 1-15
Other 5000- to 6000-level courses as advised
 
In addition, the following items also must be completed:
a.  Minimum of 30 semester hours of graduate credit, of which no more than six hours are counted from the category of
M.S. thesis or Ph. D. dissertation research (MBC 6960/8960)
b.  Preparation of a written M.S. thesis based upon the results of an original research investigation performed by the
student during the M.S. program at The University of Toledo.
c.  Successful oral defense of the thesis before the thesis advisory committee (consisting of the thesis adviser and two
other members) and presentation of the results of the thesis research in a seminar before the department of
medicinal and biological chemistry.  
d.  Acceptance of this thesis by the M.S. thesis adviser and the thesis advisory committee.  
e.  Maintenance of a GPA of 3.0 or higher.  


Doctor of Philosophy in Medicinal Chemistry  
Admission Requirements

Satisfactory completion of a bachelor’s degree in chemistry, biology, pharmacy or a related discipline is required. It is
assumed that the undergraduate training will include differential and integral calculus, college physics, a one-year
course in general and inorganic chemistry including a laboratory, a one-year course in organic chemistry including a
laboratory, and training in analytical chemistry. An undergraduate course in physical chemistry is recommended.  
The ability to excel in graduate studies and research must be evident based on grades from undergraduate studies,
recommendations from college faculty, results from standardized aptitude and achievement examinations (Graduate
Record Examination), and performance in research and independent study.
 
Students with M.S. degrees in medicinal chemistry or related fields may be admitted directly to the Ph.D. program.
Students without M.S. degrees may be admitted directly to the Ph.D. program, but must take 30 credits at the master’s
level prior to accruing doctoral level credits.
 
Degree Requirements
Ph.D. students need to complete the following courses as partial fulfillment of their requirement for a Ph.D. degree.
Additional graduate courses (5000 to 8000 level) may be required, as advised during the development of each student’s
plan of study.
 
MBC 5100/7100 Research Practices in Medicinal Chemistry ...................... 1
MBC 5620/7620 Biochemical Techniques ............................................... 2
MBC  5900/7900 Medicinal Chemistry Seminar  (6 hours required) ........... 1
MBC 6190/8190 Advanced Medicinal Chemistry ...................................... 4
MBC 6200/8200 Biomedicinal Chemistry ............................................... 4
MBC 6300/8300 Biomedicinal Chemistry Laboratory I ............................. 4
MBC 6310/8310 Biomedicinal Chemistry Laboratory II ............................ 4
MBC 6550/8550 Biochemistry .............................................................. 4
MBC  8960 Ph.D. Dissertation Research in Medicinal  
  Chemistry (30 hours required) ........................................................... 1-15
Select 8 hours in chemistry, biology, or medicinal and biological chemistry:
Chemistry Courses
CHEM 6330 Spectroscopic Methods ....................................................... 2-4
CHEM 6400/8400 Advanced Organic Chemistry ...................................... 2-4
CHEM 6410/8410 Organic Synthesis ..................................................... 2-4
CHEM 6420 Physical Organic Chemistry ................................................. 2-4
CHEM 6510/8510 Protein Chemistry ..................................................... 2-4
CHEM 6520/8520 Enzymology .............................................................. 2-4
CHEM 6530/8530 Nucleic Acid Chemistry ............................................... 2-4
Biology Courses
BIOL 6010/8010 Advanced Molecular Biology .......................................... 4
BIOL 6020/8020 Advanced Molecular Biology Laboratory .......................... 3
BIOL 6090/8090 Advanced Cell Biology .................................................. 4
BIOL 6100/8100 Research Methodology: Cell and Molecular Biology 3
Medicinal and Biological Chemistry Courses
MBC 5380/7380 Medicinal and Poisonous Plants ...................................... 3
MBC 6100/8100 Advanced Immunology ..................................................2
MBC 6800/8800 Methods in Biotechnology ..............................................3
Other MBC courses as advised
 
In addition, all students must satisfy the following:
1.  Minimum of 60 semester hours of graduate credit beyond the master’s level (see master of science in medicinal
chemistry), including a minimum of 15 hours of courses, laboratories and seminars (exclusive of dissertation
research) and a minimum of 30 hours of Ph.D. dissertation research.  
2.  Satisfactory overall performance on a written qualifying examination covering graduate-level medicinal
chemistry, biochemistry and either organic chemistry or advanced cell/molecular biology.
3.  Selection of a doctoral research adviser, preparation of an acceptable written Ph.D. dissertation proposal in
consultation with the adviser, and the satisfactory oral defense of the proposal before the dissertation advisory
committee. The written qualifying examination and the defense of the dissertation proposal will constitute the
examination requirements necessary for advancement to candidacy for the Ph.D. in medicinal chemistry. The chair
of the doctoral dissertation advisory committee will be the student’s doctoral research adviser. The dissertation advisory committee will consist of two additional faculty, plus one member from outside the student’s department
or college.  
4.  Subsequent to admission to candidacy for the Ph.D. degree, the student is expected to spend a minimum of two
semesters in full-time study at The University of Toledo.  
5.  Preparation of a Ph.D. dissertation based on the results of an original research investigation performed by the
student during his/her Ph.D. program at The University of Toledo.  
6.  Successful oral defense of the dissertation before the dissertation advisory committee and presentation of the
results of the dissertation research in a seminar before the department of medicinal and biological chemistry.  
7.  Acceptance of the dissertation by the Ph.D. dissertation adviser and the dissertation advisory committee.  
8.  Maintenance of a GPA of 3.0 or higher

Doctor of Pharmacy Degree Programs
The Doctor of Pharmacy degree for applicants having, among other qualifications, a B.S. in Pharmacy, is unavailable at
this time.


Combined Pharm.D. – Ph.D. in Medicinal Chemistry Program

Admission Requirements
Students who are admitted to both programs separately may pursue both degrees concomitantly.
Program Requirements
Although the requirements for both programs will be met, there is some overlap and flexibility, allowing a student to
complete graduate-level requirements for both degrees in four to four and a half years. In general terms, students will
follow the sequence for the Pharm.D. curriculum during the first four semesters, taking one graduate-level medicinal
chemistry course each semester. In the fifth semester, students will take the required Pharm.D. clerkships, plus the two-
hour seminar, with at least one clerkship rotation involving a research experience. The Ph.D. requirement for MBC
6550 (Biochemistry) will be waived. Beginning with sixth semester (summer following the second year), students will
complete the requirements for the Ph.D. in medicinal chemistry.
 
Last Updated: 6/26/15