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Health Science Campus
Block Health Science Building

Mail Stop # 1007
3000 Arlington Avenue
Toledo, Ohio 43614-2598
Phone: 419.383.4109
Fax: 419.383.3008

Xin Wang, M.D., Ph.D.

Assistant Professor

1995:  B.S., Tianjin Medical University, Tianjin, China
2000:  M.D., Anesthesiology, Tianjin Medical University, Tianjin, China
2006:  Ph.D., Neuroscience, University of Toledo

Research Interests:
1.  Development of post-traumatic psychiatric and neurological disorders, particularly PTSD and pain
2.  Application of neuro-plasticity concept to study the mechanisms of these psychiatric and neurological disorders
3.  Using functional and structural neuroimaging techniques to study human brain abnormalities underlying these post-traumatic disorders
4.  The links between pre-traumatic factors (e.g., risky genotypes) and development of post-traumatic disorders

Professional Interests: functional Magnetic Reonance Imaging (fMRI), post traumatic stress disorder

Wang X, Wang G. Application of porpofol anesthesia in the operation of rental insufficiency patients. Journal of Anesthesia and Relative Clinical Medicine. 4(1):27-8 (in Chinese);1996.

Wang G, Xie H, Wang X, Yu Y. Reptilase enhances coagulation during anesthesia. Chinese Pharmacy. 8 (supplement):144-5 (in Chinese); 1997.
Wall JT, Xu J, Wang X. Human brain plasticity: an emerging view of the multiple substrates and mechanisms that cause cortical changes and related sensory dysfunctions after injuries of sensory inputs from the body. Brain Research Reviews. 39(2-3):181-215; 2002.
Xie H, Wang X, Liu G, Wang GL. Analgesic effects and pharmacokinetics of a low dose of ketamine preoperatively administered epidurally or intravenously. Clinical Journal of Pain.
19(5):317-22; 2003.
Wang X, Wall JT. Cortical influences on sizes and rapid plasticity of tactile receptive fields in the dorsal column nuclei. Journal of Comparative Neurology. 489(2):241-8; 2005.
Wang X, Wall JT. Cortical influences on rapid brainstem plasticity. Brain Research. 1095:73-84; 2006.
Wang X, Xie H, Wang GL. Improved postoperative analgesia with coadministration of preoperative epidural ketamine and midazolam. Journal of Clinical Anesthesia. 18(8):563-9; 2006.
Xie H, Dong ZQ, Ma F, Bauer WR, Wang X, Wu GC. Involvement of serotonin 2A receptors in the analgesic effect of tramadol in mono-arthritic rats. Brain Research. 1210:76-83; 2008.
Geha PY, Baliki MN, Wang X, Harden RN, Paice JA, Apkarian AV. Brain dynamics for perception of tactile allodynia (touch-induced pain) in postherpetic neuralgia. Pain.138(3):641-56; 2008.

Wang X, Bauer W, Chiaia N, Dennis M, Gerken M, Hummel J, et al. Longitudinal MRI evaluations of human global cortical thickness over minutes to weeks. Neuroscience Letters. 441(2):145-8; 2008.
Wang X, Gerken M, Dennis M, Mooney R, Kane J, Khuder S, Xie H, Bauer WR, Apkarian AV, Wall JT. Profiles of precentral and postcentral cortical mean thicknesses in individual subjects over acute and subacute time-scales. Cerebral Cortex. 20(7):1513-22; 2010.
Wang X, Garfinkel SN, King AP, Angstadt M, Dennis MJ, Xie H, Welsh RC, Tamburrino MB, Liberzon I. A multiple-plane approach to measure the structural properties of functionally active regions in the human cortex. Neuroimage. 49(4):3075-85; 2010.
Kim P, Leckman JF, Mayes LC, Feldman R, Wang X, James E. Swain. The plasticity of human maternal brain: longitudinal changes in brain anatomy during the early postpartum period. Behavioral
Neuroscience. 124(5):695-700; 2010.
Sripada RK, King AP, Garfinkel SN, Wang X, Sripada C, Welsh RC, Liberzon I. Altered resting-state amygdala functional connectivity in PTSD. Journal of Psychiatry Neuroscience 37(4):241-9; 2012.
Sripada RK, King AP, Welsh RC, Garfinkel SN, Wang X, Sripada CS, Liberzon I. Neural dysregulation in posttraumatic stress disorder: Evidence for disrupted equilibrium between salience and default mode brain networks. Psychosomatic Medicine 74(9):904-11; 2012.
Xie, H, Kane, J, Dennis, MJ, Mooney R, Bauer WR, Wang X, Wall JT. Case series evidence for changed interhemispheric relationships in cortical structure in some amputees. Journal of Clinical Neuroscience.
20(4):523-6; 2013.
Lubomirsky B, Wang X(co-first author and corresponding author), Xie H, Smirnoff JB, Biehn TL, Contractor AA, Elhai JD, Sutu C, Brickman KR, Liberzon I, McLean SA, Tamburrino MB.  Preliminary study on the relationship between visitation in the emergency department and post-traumatic mental health. Social Work in Mental Health (accepted 8/24/2013).



Last Updated: 10/16/15