Psychiatry

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Health Science Campus
Ruppert Health Center
Basement, Room # 0079
Phone: 419.383.5695
Fax: 419.383.3031  webmaster@utoledo.edu

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                                  UT Department of Psychiatry Research 
Current Research Projects  

MilitaryThe Ohio Army National Guard Mental Health Initiative
Department of Defense Congressionally Directed Medical Research Program: W81XHW-07-1-0409
Principle Investigators:  Joseph Calabrese, MD (Case Medical Center), Marijo Tamburrino, MD (UT Medical Center)

Description: This 10-year longitudinal study, that began enrollment in October 2008, is a clinical epidemiology and health services project to explore risk and resilience factors for combat-related posttraumatic psychopathology and post-combat adjustment. DNA saliva samples are also collected. 


Ohio GuardEarly Intervention to Reduce Alcohol Misuse and Abuse in the Ohio Army National Guard
Congressionally Directed Medical Research Program: 13277015
Principle Investigator:
Fred Blow, PhD (University of Michigan), Co-PI's Joseph Calabrese, MD (Case Medical Center), Marijo Tamburrino, MD (UT Medical Center); Co-Investigator: John M. Wryobeck, PhD (UT Medical Center)

Description: This is a 5 year study which begins in 2014 and will develop and test a Web- and text- based alcohol brief intervention and compare it to an enhanced usual care condition for National Guard members in the state of Ohio who meet criteria for unhealthy drinking.


DNANeuroimaging and Genetic Investigation of Resilience and Vulnerability to PTSD in the Ohio National Guard and Army Reserve Cohort
Supported by Translational Research Stimulation Award of the University of Toledo & Promedica Health System 
Investigators:
Marijo Tamburrino, MD, Xin Wang, PhD and Ahmed Janjua, MD (ProMedica)

Description:This study is an extension of ongoing collabration among Ann Arbor VA Medical Center, Case West Reserve University, and University of Toledo on Ohio National Gruard Project. We will explore the brain and genetic mechanisms of resilience and vulnerability of PTSD in veterans.


ACTACT Against Violence Raising Safe Kids Program: Parent and Child Outcomes
Investigator:
Michele Knox, PhD

Description:This multi-site study examines the effects of the ACT RSK program on child maltreatment and related parenting and child outcomes. The study also addresses characteristics of parents and parenting that relate to harsh discipline and abuse.


CardiacRehabEffects of Depression and Anxiety on Adherence to Cardiac Rehabilitation
Investigators:
Angele McGrady, PhD, Daylnn Badenhop, PhD  (UT Cardiac Rehabilitation), Ron McGinnis, MD

Description: This study examines the role of depressive and anxious symptoms on adherence to structured cardiac rehabilitation and the potential of a brief stress management intervention to increase adherence.


ImagingLongitudinal MRI study of PTSD Development within Weeks after Trauma
Supported by National Institute of Mental Health and William Bauer fMRI Research Fund.
Investigator:Xin Wang, PhD

Description: this study explores the risk factors for PTSD development in the early post traumatic period in order to design effective approaches to prevent PTSD. The trauma (e.g., motor vehicle accident) survivors are examined using psychological questionnaires and MRI techniques. Patient’s psychological conditions, as well as brain functions and structures, in the days to weeks after trauma are used to predict the PTSD symptoms in the long-term.  


ScoldCharacteristics of Mental Health Treatment Seeking Children and Youths
Investigators:
Michele Knox, PhD, Kimberly Hunter, PhD

Description: This study examines the characteristics of children and youths who seek outpatient mental health treatment, with a focus on sleep issues, media violence exposure and parental discipline practices.


ChildAdvocacyThe Effects of Training in Child Advocacy and Child Abuse Prevention and Intervention for First Year Medical Students
Investigator:
Michele Knox, PhD

Description: The purpose of this study is to examine the effects of training in child advocacy on students' preparedness to prevent and intervene in cases of suspected child maltreatment.



Recent Faculty Publications 

 2013-2014

Haskett, M.E., Loehman, J.L., & Burkhart, K. (2014). Parenting interventions in shelter settings: A qualitative review of the literature. Child and Family Social Work. doi: 10.1111/cfs.12147

Knox, M., & Burkhart, K., (2014). A multi-site study of the ACT raising safe kids program: Predictors of outcomes and attrition. Youth Services Review, 39, 20-24. doi: 10.1016/j.childyouth.2014.01.006

Alastal, Y., Hasan S., Chowdhury, MA., Hammad,T., Safi, F., Rapport, D., Assaly, R. (2014). Hypertriglyceridemia Induced Pancreatitis in Psychiatric Patients: A case report and review of literature. American Journal of Therapeutics, 21(4).

Biehn, T.L., Elhai, J.D., Seligman, L.D., Tamburrino, M., Armour, C., Forbes, D. (2013). Underlying dimensions of DSM-5 posttraumatic stress disorder and major depressive disorder symptoms. Psychological Injury and Law, 6, 290-298.

Contractor, A.A., Mehta, P., Tiamiyu, M.F., Hovey, J.D., Geers, A., Charak, R., Tamburrino, M.B., Elhai, J.D. (2014, January). Relations between PTSD and distress dimensions in an Indian child/adolescent sample following the 2008 Mumbai terrorist attacks. Journal of Abnormal Child Psychology, 42, 925-935. January 2014

Hoggatt, K.J., Presscott, M.R., Goldmann, E., Tamburrino, M.B., Calabrese, J.R., Liberzon, I., et.al. The prevalence and correlates of risky driving behavior among National Guard soldiers. Traffic Injury Prevention (accepted February 18, 2014)

Gewirtz, A., Burkhart, K.,Loehman, J.L., & Haukebo, B. (2014). Research on programs designed to promote positive parenting. In M.E. Haskett, S. Perlman, & B.A. Cowan (Eds.). Supporting Families Experiencing Homelessness (pp. 173-186). New York, NY: Springer.

Brickman, K.R., Blair, A.B., Tamburrino, M.B., Dzurik, A.D., Xie, H., Smirnoff, J.B., Wang, X. Quantitative Minor Injury Scale: pilot study of a scale to measure level of minor injury after motor vehicle collisions. Translation: the UT Journal of Medical Sciences (accepted June, 2014)

Reardon, C., May, M.A., Williams, K.S. (2014). Psychiatry Resident Outpatient Clinic Supervision: How Training Directors Are Balancing Patient Care, Education, and Reimbursement. Academic Psychiatry, 38(4), 476-480.

Cerda, M., Richards, C., Cohen, G.H., Calabrese, J.R., Liberzon, I., Tamburrino, M., et.al. Civilian stressors associated with post-deployment alcohol use disorders among National Guard soldiers returning from Operation Iraqi Freedom and Operation Enduring Freedom. American Journal of Preventive Medicine (accepted May 13, 2014)

Rapport, D. Paul, P. McGrady, A. Kaplish, D. McGinnis, R. Whearty, K. (2013). “Comparing Treatment Outcomes of Bipolar Patients Between Psychiatry Residents and Attending Physicians” Academic Psychiatry, 2013, 37, 329.

Koning JC, Gage EG, Sarhan M, Gaudin D, McGinnis R, Atallah. (2014). Exacerbation of Major Depression in a Patient with a Peripheral Nerve Stimulator. Journal of Anesthesia and Clinical Research, 5, 392. doi:10.4172/2155-6148.1000392

Liberzon, I., King, A., Ressler, K., Almli, L., Zhang, P., Ma, T., Cohen, G., Tamburrino, M., Calabrese, J.R., Galea, S. ADRB2 gene polymorphism interacts with childhood trauma in conveying risk for adult posttraumatic stress disorder (PTSD). JAMA Psychiatry. (Accepted March 4, 2014)

Fine, T.H., Ateka, C.A., Tamburrino, M.B., Elhai, J.D., Prescott, M.R., Cohen, G.H., et.al. (2013). Validation of the telephone-administered PHQ-9 against the in-person administered SCID-I major depression module. Journal of Affective Disorders, 150 (3), 1001-1007.

Knox, M. S., Pelletier, H., & Vieth, V. (2013). Improving future physicians' responses to adolescent maltreatment. In Sher & Merrick (Eds), Adolescent Psychiatry. De Gruyter:  Berlin, Germany.  (Adapted from: Educating medical students about adolescent maltreatment. International Journal of Adolescent Medicine and Health), pp. 93-106.

Walsh, K., Galea, S., Cerda, M., Richards, C., Liberzon, I., Tamburrino, M.B., et.al. Associations between unit support and deployment-related sexual harassment and assault among National Guard Service Members. Women’s Health Issues (accepted May 6, 2014).

Goodwin, R.D., Cohen, G., Tamburrino, M., Calabrese, J.R., Liberzon, I., Galea, S. Mental health service use in a representative sample of National Guard soldiers. Psychiatric Services (accepted March 26, 2014)

 2012-2013

Military

Prescott, M.R., Tamburrino, M., Calabrese, J., Liberzon, I., Slembarski, R., Shirley, E., et.al. (2014, March). Validation of lay-administered mental health assessments in a large Army National Guard cohort. International Journal of Methods in Psychiatric Research, 23(1), 109-119.

Military

Fine TH, Ateka CA, Tamburrino MB, Elhai JD, Prescott MR, Cohen GH, Shirley E, Chan PK, Goto T, Slembarskid R, Liberzon I, Galea S,. Calabrese JR. Validation of the telephone-administered PHQ-9 against the in-person administered SCID-I major depression module. Journal of Affective Disorders; September 2013; 150 (3): 1001-1007

ACT

Burkhart, K., Knox, M. & Brockmyer, J. Pilot Evaluation of the ACT Raising Safe Kids Program on children's bullying behavior.   Journal of Child and Family Studies, 2012.

ArticleKnox, M., Pelletier, H. & Vieth, V.  (2013). Educating medical students about adolescent maltreatment. International Journal of Adolescent Medicine and Health, 25(3), 301-308.  doi:  10.1515/ijamh-2013-0066

 WellnessMcGrady, A., Brennan, J., Lynch, & Whearty, K. A. (2012). Wellness program for first year medical students. Applied Psychophysiology and Biofeedback, 37(4): 253-60.

ACTKnox, M., Burkhart, K. & Cromley, A. Supporting positive parenting in community health centers: The ACT Raising Safe Kids Program. Journal of Community Psychology. 41:395 – 407, 2013.

 ArticlePanchajanya, P., McGinnis, R., McGrady, A., Whearty, K., & Rapport, D. A comparison of treatment outcomes of bipolar disorder patients at an academic medical center treated by psychiatric residents and attending physicians", submitted to Academic Psychiatry (MS ID APPI-AP-11-12-0220), 2012. 

 ArticleRais, T. Valproate induced hyperammonemic encephalopathy: a case report, Innovations in Clinical Neuroscience (volume 10, numbers 5-6, May-June 2013).

 ArticleBrennan, J. McGrady, A., Whearty, K., Lynch D., Rapport D., Schaefer, P. (2012). Emotional status of third year medical students and their responses to a brief intervention. Annals of Behavioral Science and Medical Education, 18(2): 10-14.

 MilitaryMarshall BD, Prescott MR, Liberzon I, Tamburrino MB, Calabrese JR, Galea S. "Coincident Posttraumatic Stress Disorder and Depression Predict Alcohol Abuse during and after Deployment among Army National Guard Soldiers." Drug and Alcohol Dependence, 2012, 124(3):193-199.

 MilitaryBiehn TL, Contractor A, Elhai JD, Tamburrino M, Fine T, Prescott MR, Shirley E, Chan P, Slembarski R, Liberzon I, Calabrese JR, Galea S. Relations Between the Underlying Dimensions of PTSD and Major Depression using an Epidemiological Survey of Deployed Ohio National Guard Soldiers. Journal of Affective Disorders, Jan. 10, 2013; 144(1-2):106-111.

 MilitaryGoodwin RD, Prescott M, Tamburrino M, Calabrese JR, Liberzon I, Galea S. Cigarette Smoking and Subsequent Risk of Suicidal Ideation among National Guard Soldiers. Journal of Affective Disorders, Feb. 15, 2013; 145(1):111-114.

 MilitaryElhai JD, Contractor A, Tamburrino M, Fine TH, Prescott MR, Shirley E, Chan PK, Slembarski R, Liberzon I, Galea S, Calabrese JR. The Factor Structure of Major Depression Symptoms: A Test of Four Competing Models Using the Patient Health Questionnaire – 9. Psychiatry Research, Oct. 30, 2012; 199(3):169-173.

 MilitaryMarshall BDL, Prescott MR, Liberzon I, Tamburrino MB, Calabrese JR, Galea S. Posttraumatic Stress Disorder, Depression, and HIV Risk Behavior among Army National Guard Soldiers. Journal of Traumatic Stress, 2013; 26(1):64-70.

 MilitaryGoodwin RD, Prescott M, Tamburrino M, Calabrese JR, Liberzon I, Galea S. Smoking is a Predictor of Depression Onset among National Guard Soldiers. Psychiatry Research, 2013 April 30; 206(2-3):321-3. Epub 2013 Jan 3. PMID:23291043.

 ArticleEilbeck NK, Tamburrino MB. Sleepless and Paranoid: Cases that Test Your Skills, Current Psychiatry, April 2013; 12(4):39-43.

 ArticleSmith MK, Tamburrino MB, Nagel RW, Lynch DJ. Comorbidity of Anxiety in Depressed Primary Care Patients. Psychiatry On-Line, May 25, 2013. http://www.priory.com/psychiatry/depression_comorbid_anxiety.htm

 ArticleLubomirsky, B., Wang, X., Xie, H., Smirnoff, J.B., Biehn, T.L., Contractor, A.A., Elhai, J.D., Sutu, C., Brickman, K.R., Liberzon, I., McLean, S.A., Tamburrino, M.B. (2013, November). Preliminary study on the relationship between visitation in the emergency department and post-traumatic mental health. Social Work in Mental Health. Published online https://www.tandfonline.com/doi/full/10.1080/15332985.2013.841611

 ChapterWryobeck JM, Haines ME, Wynkoop TE, Swanson MA. Depressive Disorders. In C.A. Noggle & R.S. Dean, (editors). The Neuropsychology of Psychopathology. New York: Springer Publishing Company; 2013. p. 201-220.

 MRISripada RK, King AP, Garfinkel SN, Wang X, Sripada C, Welsh RC, Liberzon I. Altered resting-state amygdala functional connectivity in PTSD. Journal of Psychiatry Neuroscience 37(4):241-9; 2012

 MRISripada RK, King AP, Welsh RC, Garfinkel SN, Wang X, Sripada CS, Liberzon I. Neural dysregulation in posttraumatic stress disorder: evidence for disrupted equilibrium between salience and default mode brain networks. Psychosomatic Medicine 74(9):904-11; 2012.

 MRIXie, H, Kane, J, Dennis, MJ, Mooney R, Bauer WR, Wang X, Wall JT. Case series evidence for changed interhemispheric relationships in cortical structure in some amputees. Journal of Clinical Neuroscience. 20(4):523-6; 2013

 Chapter
McGrady, A., Moss, D. Pathways to Illness, Pathways to Health (March 2013). Springer Publishing, New York, New York.

 2011-2012

ArticleKnox, M., Burkhart, K., & Khuder, S. (In press). Parental hostility and depression as predictors of young children’s aggression and conduct problems. Journal of Aggression, Maltreatment & Trauma.

ACTKnox, M., Burkhart, K., & Howe, T. (In press). Effects of the ACT Raising Safe Kids parenting program on children’s externalizing problems. Family Relations.

BookChapter

Wryobeck JM, Rubenfire M. Pulmonary Arterial Hypertension: psychosocial implications and treatment. In: M. Riba, L. Wulsin, & M. Rubenfire, (editors). Psychiatry and Heart Disease: the Mind, Brain, and Heart. Wiley-Blackwell, John Wiley & Sons, Ltd., West Sussex, UK; 2012. p. 88-98.

 

Wellness McGrady, A., Brennan, J., Lynch, & Whearty, K. A wellness program for first year medical students. Applied Psychophysiology and Biofeedback, 2012.

ResearchArticle Sarwar, S., McGinnis, R., "Topiramate-induced Dissociative Disorder" Innovations in Clinical Neuroscience, Vol. 8, No. 8, August 2011. 

ResearchArticleKnox, M., Lentini, J., Cummings, T., McGrady, A., Whearty, K., & Sancrant, L. (In press). Game-based biofeedback for pediatric anxiety and depression. Mental Health in Family Medicine.

MilitaryElhai JD, Naifeh JA, Forbes D, Ractliffe KC, Tamburrino M. Heterogeneity in Posttraumatic Stress Disorder’s Clinical Presentations Among Medical Patients: Testing Factor Structure Variation Using Factor Mixture Modeling. Journal of Traumatic Stress, 2011;24(4):435-443.

MilitaryCalabrese JR, Prescott M, Tamburrino MB, Liberzon I, Slembarski R, Goldmann E, Shirley E, Fine T, Goto T, Wilson K, Ganocy S, Chan P, Serrano MB, Sizemore J, Galea S. “PTSD Comorbidity and Suicidal Ideation associated with PTSD within the Ohio Army National Guard.” The Journal of Clinical Psychiatry, 2011;72(8):1072-1078

MilitaryGoldmann E, Calabrese J, Prescott M, Tamburrino M, Liberzon I, Slembarski R, Shirley E, Fine T, Goto T, Wilson K, Ganocy S, Chan P, Serrano M, Sizemore J, Galea S. “Potentially Modifiable Pre-, Peri-, and Postdeployment Characteristics Associated with Deployment-Related Posttraumatic Stress Disorder Among Ohio Army National Guard Soldiers.” Ann Epidemiol., 2012 Feb;22(2):71-78.

ResearchForan-Tuller William K, Robiner W, Breland-Noble A, Otey-Scott S, Wryobeck J, King C, Sanders K. Early Career Boot Camp: A Novel Mechanism for Enhancing Early Career Development for Psychologists in Academic Healthcare, J Clin Psychol Med S 2012:19:117-125.

ArticleSripada RK, King AP, Garfinkel SN, Wang X, Sripada C, Welsh RC, Liberzon I. Altered Resting-State Amygdala Functional Connectivity in PTSD. J Psychiatry Neurosci. 2012:37(4):241-9

MRIXie, H., Kane, J., Dennis, M.J., Mooney, Bauer, W.R., Wang, X., & Wall, J.T. (In press) Case series evidence for changed interhemispheric relationships in cortical structure in some amputees. Journal of Clinical Neuroscience. (in press)

 Article
Feldman L, Williams KS, Knox M. Coates J, Report. "Influencing Controlled Substance Prescribing: Attending and Resident Physician Use of a State Prescription Monitoring Program." Pain Medicine. June 2012.

ArticleTamburrino, MB, Nagel RW, Lynch DJ. Managing Antidepressants in Primary Care: Physicians' Treatment Modifications. Psychological Reports, 2011;108(3):799-804.

MilitaryMarshall BD, Prescott MR, Liberzon I, Tamburrino MB, Calabrese JR, Galea S. "Coincident Posttraumatic Stress Disorder and Depression Predict Alcohol Abuse during and after Deployment among Army National Guard Soldiers." Drug and Alcohol Dependence, 2012, 124(3):193-199.

MilitaryGoodwin RD, Prescott M, Tamburrino M, Calabrese JR, Liberzon I, Galea S. Cigarette Smoking and Subsequent Risk of Suicidal Ideation among National Guard Soldiers. Journal of Affective Disorders. (Accepted 5-2-2012)

ChapterWilliams KS, Franco-Bronson K., "Emotional and Psychiatric Problems in Patients with Cancer." In Handbook of Cancer Chemotherapy 8th ed., RT Skeel, S. Khleif eds., Chapter 32, 678-693, 2011.

ArticleFeldman L, Williams KS, Coates J, Knox M. Awareness and Utilization of a Prescription Monitoring Program Among Physicians. Journal of Pain and Palliative Care Pharmacotherapy, Vol. 25, No. 4, Pages 313-317, 2011.

MilitaryBiehn TL, Contractor A, Elhai JD, Tamburrino M, Fine T, Prescott MR, Shirley E, Chan P, Slembarski R, Liberzon I, Calabrese JR, Galea S. Relations Between the Underlying Dimensions of PTSD and Major Depression using an Epidemiological Survey of Deployed Ohio National Guard Soldiers. Journal of Affective Disorders. (Accepted 6-12-2012)

ArticleElhai JD, Contractor A, Tamburrino M, Fine TH, Prescott MR, Shirley E, Chan PK, Slembarski R, Liberzon I, Galea S, Calabrese JR. The Factor Structure of Major Depression Symptoms: A Test of Four Competing Models Using the Patient Health Questionnaire – 9. Psychiatry Research. (Accepted 5-20-2012)

ArticleKnox, M., Lentini, J., Cummings, T., McGrady, A., Whearty, K., & Sancrant, L. Game-based biofeedback for pediatric anxiety and depression. Mental Health in Family Medicine 8: 195-203, 2011.

 

 
Last Updated: 6/26/15