Department of Physiology and Pharmacology

Tao Yang, PhD

 

 

TaoAssistant Professor 

419.383.4139

Tao.Yang2@UToledo.Edu

Microbiota and Drug Metabolism in Hypertension Research Laboratory

 

 

 

 

 

 

 

education

Ph.D.                                                  University of Florida, Gainesville, FL

Master of Life Sciences                  Jilin University, Changchun, China

Bachelor of Life Sciences              Jilin University, Changchun, China

 

honors and awards

2014   Outstanding International Student Award, University of Florida

2015   New Investigator Award, AHA

2015   Best of Specialty, AHA Scientific Session

2016   Data Sciences International Outstanding Graduate Student, Neural Control & Autonomic Regulation Section, APS

2016   Charles F. Simpson Memorial Scholarship Award, College of Vet Medicine, University of Florida

2018   Experimental Biology Meeting Travel Award, APS

2018   International Hypertension Meeting Travel Award, International Society of Hypertension (ISH)

2018   Mcknight Brain Institute Postdoctoral Fellowship, University of Florida

2019   Trainee Research Recognition Award, Physiological -Omics group, APS

2019   Biocodex Microbiota USA Foundation Research Grant $50,000 (PI)

2019   New Investigator Award, AHA

2019   Best of Specialty, AHA

2020   Star Reviewer for the APS Journal Physiological Genomics

2021   Research Recognition Award, Cardiovascular Section, APS

2021   Stephanie Watts Career Development Award Finalist

2022   Experimental Biology Blue Ribbon Pick, ASPET

 

Society memberships

American Heart Association

American Physiological Society

International Society of Hypertension

American Society of Pharmacology and Experimental Therapeutics

 

Journal editorial board Memberships

Hypertension

Physiological Genomics

 

media reports

  1. Gut bacteria may contribute to blood pressure medicine resistance. EurekAlert! ; CathLabDigest; MedicalXpress.
  2. Gut bacteria may be an important factor in blood pressure medicine resistance. SciTechDaily.
  3. Resistant high blood pressure: Gut bacteria may be to blame. Medical News Today.
  4. Gut bacteria may explain why hypertension drugs don’t work for everyone with high blood pressure. PhillyVoice.
  5. Intestinal flora can cause resistance to drugs.
  6. Intestinal bacteria can contribute to resistance to blood pressure medications. WORLDFACE.
  7. High blood pressure: Gut bacteria may contribute to drug resistance.
  8. Gut bacterium may be an important factor in resistance to antihypertensive medications. News Medical Life Sciences.
  9. Gut bacteria may contribute to blood pressure drug resistance. Drug Target Review.
  10. Your gut health might be making it harder to keep your blood pressure in check. Eating Well.
  11. Med-munching gut bacteria. Spirituality&Health.
  12. Gut microbiome linked to resistant hypertension.
  13. Gut bacteria may interfere with the effectiveness of blood pressure medications. NHLBI
  14. Study finds gut bacteria can make blood pressure medication less effective. UToledo News. https://news.utoledo.edu/index.php/05_26_2022/study-finds-gut-bacteria-can-make-blood-pressure-medication-less-effective
  15. Las bacterias intestinalis pueden reducier la eficacia de la medicacion antihipertensiva. JANO.es

 

selected publications

  1. 1) Yang T*, Mei X, Tackie-Yarboi E, Akere MT, Kyoung J, Mell B, Yeo JY, Cheng X, Zubcevic J, Richards EM, Pepine CJ, Raizada MK, Schiefer IT, Joe B*. Identification of a gut commensal that compromises the blood pressure-lowering effect of ester angiotensin-converting enzyme inhibitors. Hypertension. 2022. * Corresponding. Media Reported
  2. Kyoung J, Yang T*. Depletion of gut microbiota enhances blood pressure-lowering effect of captopril: implication of gut microbiota in resistant hypertension. Hypertension Research. 2022. * Corresponding
  3. Yang T, Chakraborty S, Mandal J, Mei X, Joe B. Microbiota and Metabolites as Factors Influencing Blood Pressure Regulation. Comprehensive Physiology. 2021 Apr 1;11(2):1731-1757. doi: 10.1002/cphy.c200009. PubMed PMID: 33792901.
  4. Yang T, Magee KL, Colon-Perez LM, Larkin R, Liao YS, Balazic E, Cowart JR, Arocha R, Redler T, Febo M, Vickroy T, Martyniuk CJ, Reznikov LR, Zubcevic J. Impaired butyrate absorption in the proximal colon, low serum butyrate and diminished central effects of butyrate on blood pressure in spontaneously hypertensive rats. Acta Physiol (Oxf). 2019 Jun;226(2):e13256. doi: 10.1111/apha.13256. Epub 2019 Feb 20. PubMed PMID: 30656835; PubMed Central PMCID: PMC7199780. Top Cited Article 2019-2020
  5. Yang T, Aquino V, Lobaton GO, Li H, Colon-Perez L, Goel R, Qi Y, Zubcevic J, Febo M, Richards EM, Pepine CJ, Raizada MK. Sustained Captopril-Induced Reduction in Blood Pressure Is Associated With Alterations in Gut-Brain Axis in the Spontaneously Hypertensive Rat. J Am Heart Assoc. 2019 Feb 19;8(4):e010721. doi: 10.1161/JAHA.118.010721. PubMed PMID: 30755073; PubMed Central PMCID: PMC6405665.
  6. Yang T, Richards EM, Pepine CJ, Raizada MK. The gut microbiota and the brain-gut-kidney axis in hypertension and chronic kidney disease. Nat Rev Nephrol. 2018 Jul;14(7):442-456. doi: 10.1038/s41581-018-0018-2. Review. PubMed PMID: 29760448; PubMed Central PMCID: PMC6385605.
  7. Yang T, Santisteban MM, Rodriguez V, Li E, Ahmari N, Carvajal JM, Zadeh M, Gong M, Qi Y, Zubcevic J, Sahay B, Pepine CJ, Raizada MK, Mohamadzadeh M. Gut dysbiosis is linked to hypertension. 2015 Jun;65(6):1331-40. doi: 10.1161/HYPERTENSIONAHA.115.05315. Epub 2015 Apr 13. PubMed PMID: 25870193; PubMed Central PMCID: PMC4433416.
Last Updated: 7/6/22