Kandace J. Williams, Ph.D.
Senior Associate Dean for College of Medicine & Life Sciences Graduate
Professor of Cancer Biology
kandace.williams@utoledo.edu
EDUCATION:
| B.S. | 1980 | Medical Technology | University of Alaska, Anchorage, AL |
| Ph.D. | 1987 | Pharmacology and Toxicology | Dartmouth Medical School, Hanover, NJ |
| Post-Doc | 1991 | Pathology | Joseph Gottstein Memorial Cancer Research Laboratory, Univ. of Washington College of Medicine, Seattle, WA |
RESEARCH INTERESTS:
Since 2013, I have been Associate Dean for the College of Medicine & Life Sciences
(UT-COM&LS) Graduate Programs. The Associate Dean position requires me to be involved
with all of the COM&LS graduate programs, including the MD/PhD dual degree program,
all of the PhD and MSBS Biomedical Science Program training tracks, MSBS-Medical Science
for premedical students, MSBS-Medical Physics, MSBS-Oral Biology for Dentistry residents,
MSBS-Orthopedic Sciences, MSBS-Human Donation Sciences, MSBS-Physician Assistant studies,
and MSBS-Assistant in Pathology. Several of the above graduate degrees are in clinical
areas of study, requiring much different training than for a research career, however,
all of the clinical programs are very well organized by each Program Director. The
majority of my time is spent with the Biomedical Science Program research training
tracks.
REPRESENTATIVE PUBLICATIONS:
Williams, K. DNA Damage Response Genes. In: Schwab M. (Ed.) Encyclopedia of Cancer:
SpringerReference (www.springerreference.com). Springer-Verlag Berlin Heidelberg, 2012. DOI: 10.1007/SpringerReference_173167
2012-05-08 09:29:38 UTC
Edelbrock, M., Kaliyaperumal S., and Williams, K.J. (2013) Structural, molecular and cellular functions of MSH2 and MSH6 during DNA mismatch repair, damage signaling and other noncanonical activities. Mutat Res 743–744, 53–66.
Williams, K.J. and Sobol, R.W. (2013) Mutation research/fundamental and molecular mechanisms of mutagenesis. Mutat Res 743– 744, 1-3.
Blomquist, T.M., Brown, R.D., Crawford, E.L., de la Serna, I., Williams, K., Yoon, Y., Hernandez, D-A., and Willey, J.C. (2013) CEBPG Exhibits Allele-Specific Expression in Human Bronchial Epithelial Cells. Gene Regul Syst Bio 7, 125-138.
Gupte, M., Tuck, A.N., Sharma, V.P. and Williams, K.J.(2013) Major differences between tumor and normal human cell fates after exposure to chemotherapeutic monofunctional alkylator. PLoS One 8 (9). E74071.
Kaliyaperumal, S., Patrick, S.M., Williams, K.J. (2011) Phosphorylated hMSH6: DNA mismatch versus DNA damage recognition. Mutat Res 706:36-45.
Mueser, T.C., Hinerman, J.M., Devos, J.M., and Williams, K.J. (2010) Structural analysis of bacteriophage T4 DNA replication: a review in the Virology
Journal series on bacteriophage T4 and its relatives.Virol J 7:359.
Mueser, T.C., Williams, K.J. (2011) Alkylation chemotherapy: Mechanistic potential
and pitfalls. In: Advances in Genetics Research (K.V. Urbano, ed.), Nova Science
Publishers, pp. 179-196.
Schroering, A., Kothandapani, A., Patrick, S.M., Kaliyaperumal, S., Sharma, V.P.,
Williams, K.J. (2009) Prolonged cell cycle response of HeLa cells to low-level alkylation exposure. Cancer Res 69:6307-6314.
Edelbrock, M.A., Kaliyaperumal, S., Williams, K.J. (2009) DNA mismatch repair efficiency and fidelity are elevated during DNA synthesis in human
cells. Mutat Res 662:59-66.
Schroering, A., Williams, K.J. (2008) Rapid induction of chromatin-associated DNA mismatch repair proteins after MNNG treatment. DNA Repair 7:951-969.
Schroering, A., Edelbrock, M.A., Richards, T.J., Williams, K.J. (2007) The cell cycle and DNA mismatch repair. Exp Cell Res 313:292-304.