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The actin crosslinking protein palladin modulates force generation and mechanosensitivity
of tumor associated fibroblasts. Azatov M , Goicoechea SM , Otey C, Upadhyaya A. Sci. Rep. 6:28805, 2016.
Palladin expression is a conserved characteristic of the desmoplastic tumor microenvironment
and contributes to altered gene expression. Cannon AR, Owen MK, Guerrero MS, Kerber
ML, Goicoechea SM, Hemstreet KC, Klazynski B, Hollyfield J, Chang EH, Hwang RF, Otey CA, Kim HJ. Cytoskeleton.
72(8):402-11, 2015. Featured on the cover.
I'm coming to GEF you: Regulation of RhoGEFs during cell migration. Goicoechea SM, Awadia S, Garcia-Mata R. Cell Adh Migr. 2;8(4), 2014
Palladin promotes invasion of pancreatic cancer cells by enhancing invadopodia formation
in tumor-associated fibroblasts. Goicoechea SM, García-Mata R, Staub J, Valdivia A, Sharek L, McCulloch CAG, Hwang RF, Urrutia R,
Yeh JJ, Kim HJ and Otey CA. Oncogene 6;33(10):1265-73, 2014
Structure and function of palladin's actin binding domain. Beck MR, Dixon RD, Goicoechea SM, Murphy GS, Brungardt JG, Beam MT, Srinath P, Patel J, Mohiuddin J, Otey CA, Campbell
SL. J Mol Biol. 23;425(18):3325-37, 2013
The actin associated protein palladin is important for the early smooth muscle cell
differentiation. Jin L, Gan Q, Zieba BJ, Goicoechea SM, Owens GK, Otey CA, Somlyo AV. PLoS One 22;5(9):e12823, 2010
Isoform-specific upregulation of palladin in human and murine pancreas tumors. Goicoechea SM, Bednarski B, Stack C, Cowan DW, Volmar K, Thorne L, Cukierman E, Rustgi AK, Brentnall
T, Hwang RF, McCulloch CA, Yeh JJ, Bentrem DJ, Hochwald SN, Hingorani SR, Kim HJ,
Otey CA. PLoS One 26;5(4):e10347, 2010.
Cytoplasmic Ig-domain proteins: Cytoskeletal regulators with a role in human disease.
Otey CA, Dixon R, Stack C, Goicoechea SM. Cell Motil Cytoskeleton. 66(8):618-34, 2009
Roles of the small GTPases RhoA and Rac1 in cell behavior. Carol Otey, Silvia Goicoechea and Rafael Garcia-Mata. F1000 Biology Reports 1:4, 2009
Characterization of cortactin as an in vivo Protein Kinase D substrate: interdependence
of sites and potentiation by Src. Line De Kimpe, Katrien Janssens, Rita Derua, Milena
Armacki, Silvia Goicoechea, Carol Otey, Etienne Waelkens, Sandy Vandoninck, Jackie R. Vandenheede, Thomas Seufferlein,
and Johan Van Lint. Cell. Signal. 21(2):253-63, 2009
Palladin contributes to invasive motility in human breast cancer cells. Goicoechea SM, Bednarski B, García-Mata R, Prentice-Dunn H, Kim HJ and Otey CA. Oncogene. 28(4):587-98,
2009
The role of palladin in actin organization and cell motility.Silvia Goicoechea, Daniel Arneman and Carol Otey. Eur J Cell Biol. 87(8-9):517-25, 2008
Palladin binds to Eps8 and enhances the formation of dorsal ruffles and podosomes
in vascular smooth muscle cells. GoicoecheaSM, Arneman D, Disanza A, Garcia-Mata R, Scita G and Otey C. J. Cell Science 119(Pt
16):3316-24, 2006
Low density lipoprotein receptor-related protein is a calreticulin co-receptor that
signals focal adhesion disassembly. A.W. Orr, C. Pedraza, M.A. Paller, C. Elzie, SM Goicoechea, D. Strickland, J. Murphy-Ullrich. J. Cell Biol. 161(6):1179-89, 2003
Anti-adhesive Activity of Thrombospondin is Mediated by The N-terminal Domain of Cell
Surface Calreticulin. Goicoechea SM, Pallero MA, Eggleton P, Michalak M., Murphy-Ullrich JE. J Biol Chem. 277(40):37219-28,
2002
Nck-2 interacts with focal adhesion kinase and modulates cell motility. Goicoechea, SM; Tu, Y; Hua, Y; Chen, K; Shen, T-L; Guan, J-L; Wu, C. Int. J. Biochem. Cell. Biol.
1255:1-15, 2002
Thrombospondin mediates focal adhesion disassembly through interactions with cell
surface calreticulin. Goicoechea SM, Orr WA, Pallero MA, Eggleton P, Murphy-Ullrich JE. J. Biol. Chem. 275(46):36358-68,
2000The LIM-only protein PINCH is a binding protein for the integrin-linked kinase
(ILK). Tu, Y; Li, F; Goicoechea, SM; Wu, C, Molecular and Cellular Biology, 19(3):2425, 1999
Integrin-linked protein kinase regulates fibronectin matrix assembly, E-cadherin expression
and tumorigenicity. Wu, C; Keightley, SY; Leung-Hegesteijn, CH; Radeva, G; Coppolino,
M; Goicoechea, SM; McDonald, JA; Dedhar, S. J. Biol. Chem. 273(1):528-536, 1998
Influence of protein nutrition on calpain activity of mouse kidney: Modulation by
calpastatin. Goicoechea, SM; Conde, RD. Mol. Cell. Biochem. 166 (1/2):95-99, 19
Estimation of ubiquitin and ubiquitin mRNA content in dark senescing wheat leaves.
Pinedo, ML; Goicoechea, SM; Lamattina, L; Conde, RD. Biologia Plantarum, 38(3):321-328, 1996
Effect of dietary level of protein on the activity of mouse liver calpain. Goicoechea, SM; Tabares, L; Pucciarelli, MG; Sabas, ME; Conde, RD. Horm. Metab. Res. 26, 175-180,
1994
Book chapter:
Cell surface calreticulin-thrombospondin de-adhesive activity in Calreticulin in Health
and Disease. SM Goicoechea and J.E.Murphy-Ullrich. In Calreticulin 2nd Edition. Ed. Paul Eggleton and Marek Michalak. Landes Bioscience, Georgetown, Texas
(2002).
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