Department of Medicinal and Biological Chemistry

Ghassan M. Abushaikha, Ph.D.

 Dr. Ghassan AbushaikhaResearch Assistant Professor

  Department of Medicinal and Biological Chemistry
  Wolfe Hall, Room 2221 MC
  Phone: 419.530.1570
  E-mail: ghassan.abushaikha@utoledo.edu

 

 

Area of Research

Design, synthesis, and biological evaluation of small molecules in the fields of anticancer, antihyperlipidemia, and antiviral.

Educational background

Ph.D. in Medicinal Chemistry University of Pisa, Italy, 1997
B.S. in Pharmacy University of Camerino, Italy, 1993
B.S. in Chemistry and Pharmaceutical Technology University of Camerino, Italy, 1992

Training

Molecular modelling; structure-based drug design and molecular docking by using MOE software at Skaggs School of Pharmacy and Pharmaceutical Sciences/University of California, San Diego, 2019.

Scope of Practice/Professional Experience

The design of small molecules based on the knowledge of the target(s) structure and function. Structure-Based Drug Design (SBDD) and Docking are performed for further structural optimization. 

Awards, Honors and Grants

Grants

  1. Co-investigator, Research Project entitled: Design, Synthesis, and Biological Evaluation of PI3Ka and EGFR Inhibitors Targeting Colon and Breast Cancer, 2018. 
  2. Co-investigator. Project title: Design, Synthesis, and Biological Evaluation of a new series of CETP Inhibitors. 2017.

Awards

  1. Distinguished researcher award from Al-Zaytoonah University of Jordan in 2012.
  2. Distinguished researcher award from Al-Zaytoonah University of Jordan in 2010.
  3. Award of 15 fellowships for research work on AIDS, Istituto Superiore di Sanita, Ministry of Health, Rome, Italy, October 1995- April 1998.

Issued Patents

  1. Tariq Al-Qirim, Ghassan Shattat, Kamal Sweidan, Ghassan Abu Sheikha, Yusuf AlHiari. Benzofuran- and benzothiophene-2-carboxamide derivatives, a process for their preparation and their use as potential antihyperlipidaemic agents. Jordan Patent 47/2009.
  2. Ghassan Shattat, Tariq Al-Qirim, Moyad Shahwan, Yusuf Al-Hiari, Ghassan Abu Sheikha. N-substituted-1H-indole-2-carboxamide derivatives, a process for their preparation and their use as potential antihyperlipidaemic agents. Jordan Patent 373/2008.

Publications and Journals

UToledo Scholars

Last Updated: 10/28/21