Ghassan M. Abushaikha, Ph.D.
Research Assistant Professor
Department of Medicinal and Biological Chemistry
Wolfe Hall, Room 2221 MC
Phone: 419.530.1570
E-mail: ghassan.abushaikha@utoledo.edu
Area of Research
Design, synthesis, and biological evaluation of small molecules in the fields of anticancer, antihyperlipidemia, and antiviral.
Educational background
| Ph.D. in Medicinal Chemistry | University of Pisa, Italy, 1997 |
| B.S. in Pharmacy | University of Camerino, Italy, 1993 |
| B.S. in Chemistry and Pharmaceutical Technology | University of Camerino, Italy, 1992 |
Training
Molecular modelling; structure-based drug design and molecular docking by using MOE software at Skaggs School of Pharmacy and Pharmaceutical Sciences/University of California, San Diego, 2019.
Scope of Practice/Professional Experience
The design of small molecules based on the knowledge of the target(s) structure and function. Structure-Based Drug Design (SBDD) and Docking are performed for further structural optimization.
Awards, Honors and Grants
Grants
- Co-investigator, Research Project entitled: Design, Synthesis, and Biological Evaluation of PI3Ka and EGFR Inhibitors Targeting Colon and Breast Cancer, 2018.
- Co-investigator. Project title: Design, Synthesis, and Biological Evaluation of a new series of CETP Inhibitors. 2017.
Awards
- Distinguished researcher award from Al-Zaytoonah University of Jordan in 2012.
- Distinguished researcher award from Al-Zaytoonah University of Jordan in 2010.
- Award of 15 fellowships for research work on AIDS, Istituto Superiore di Sanita, Ministry of Health, Rome, Italy, October 1995- April 1998.
Issued Patents
- Tariq Al-Qirim, Ghassan Shattat, Kamal Sweidan, Ghassan Abu Sheikha, Yusuf AlHiari. Benzofuran- and benzothiophene-2-carboxamide derivatives, a process for their preparation and their use as potential antihyperlipidaemic agents. Jordan Patent 47/2009.
- Ghassan Shattat, Tariq Al-Qirim, Moyad Shahwan, Yusuf Al-Hiari, Ghassan Abu Sheikha. N-substituted-1H-indole-2-carboxamide derivatives, a process for their preparation and their use as potential antihyperlipidaemic agents. Jordan Patent 373/2008.