Bioinformatics Program

fundamentals in Bioinformatics

UToledo course #: BIPG5100/7100 - 3 cr 
Prerequisites:  BMSP6340/8340 Current Problems & Research Approaches in Genes and Genomes (3cr) is recommended and can be taken concurrently. However, this should not be necessary for students who have had upper-level courses in biology or biochemistry.

Offered:  Fall semester.  Lectures are posted online.

Summary: This course introduces the student to the powerful tools for accessing and analyzing biological sequence and structural information (including data from the Human Genome Project). Topics presented include sequence databases, sequence comparisons, database searches, phylogenetic analysis, protein structure, proteomics, RNA structure prediction, gene prediction and identification, genetic analysis of disease, and microarray-based studies of gene expression. For each topic the basic theory will be presented, followed by practical applications of the theory and exercises based on the lectures. There will be scheduled sessions at the UToledo Health Science Campus Bioinformatics Computer Lab to assist students in these exercises. There will also be a term project on a subject of the student's choosing (requiring instructor approval). This project will employ methods from the diverse topics covered in the lectures. 

Grading: Weekly homework assignments are worth 10 points each. The term project is worth 30 points. Midterm grades are used to assist students with determining where they stand academically in the course. Final Grading: students who complete all assignments should obtain an A or B in the course. (See syllabus at link above for grading breakdown.)

Instruction: The course is team-taught with lecturers from the faculty at the University of Toledo and Bowling Green State University.

Text: ISBN: 978-1-118-58178-0  Jonathan Pevsner, Bioinformatics and Functional Genomics, third edition, Wiley-Blackwell, copyright 2015. 


Last Updated: 8/16/22