Department of Orthopaedic Surgery
| Biomaterials, Medical Devices, and Regenerative Medicine Laboratory | ||
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| The PI | ||
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A. Champa Jayasuriya, Ph.D.
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Research Interests:
Dr. Jayasuriya is a Professor in the Department of Orthopaedic Surgery at the University
of Toledo. Dr. Jayasuriya also has an adjunct faculty appointment with the Department
of Bioengineering at the University of Toledo. Dr. Jayasuriya’s laboratory currently
investigates injectable bone graft devices to regenerate or repair damaged human bone
tissues. These injectable bone grafts mainly manufactured using natural polymer biomaterials
including chitosan biopolymer. The major advantage of injectable graft is that it
can be applied to bone defect site via an arthroscopically, a minimally invasive procedure
used in orthopaedics. Injectable bone graft devices are evaluated for biocompatibility,
biodegradation, and mechanical testing using in vitro and in vivo studies. New bone formation with bone grafts are assessed using a rat model craniomaxillofacial
bone defects which treated using bone graft devices over time. The new bone tissues
are evaluated using histology, histomorphology, Raman, micro-CT, and mechanical analysis.
In addition to bone regeneration studies, Dr. Jayasuriya’s laboratory also focuses
on delivery of drugs, antibiotics, growth factors, and cells.