Rujun Gong, MD, PhD — Publications
Peer-reviewed articles | Chapters in books | Patents
Peer-reviewed articles published in scientific journals
SELECTED Research Articles
1. Shaffner J, Chen B, Malhotra DK, Dworkin LD, Rujun Gong*.
Therapeutic Targeting of SGLT2: A New Era in the Treatment of Diabetes and Diabetic
Kidney Disease.
Frontiers in Endocrinology 12:749010.2021.
1. Sairah Sharif, Bohan Chen, Pamela Brewster, Tian Chen, Lance Dworkin, Rujun Gong*.
Rationale and Design of Assessing the Effectiveness of Short-Term Low-Dose Lithium
Therapy in Averting Cardiac Surgery-Associated Acute Kidney Injury: A Randomized,
Double Blinded, Placebo Controlled Pilot Trial.
Frontiers in Medicine 8:639402. 2021.
1. Chen B, Wang P, Liang X, Jiang C, Ge Y, Lance D. Dworkin and Rujun Gong*.
Permissive effect of GSK3β on profibrogenic plasticity of renal tubular cells in progressive
chronic kidney disease.
Cell Death and Disease 12:432. 2021
1. Chang M, Chen B, Shaffner J, Dworkin LD, Rujun Gong*.
Melanocortin System in Kidney Homeostasis and Disease: Novel Therapeutic Opportunities.
Frontiers in Physiology 12:651236.2021
1. Jiahui Zhang, Fnu Anshul, Deepak K Malhotra, Juan Jaume, Lance D Dworkin, Rujun Gong*.
Microdose Lithium Protects against Pancreatic Islet Destruction and Renal Impairment
in Streptozotocin-Elicited Diabetes.
Antioxidants (Basel). 10(1):E138. doi: 10.3390/antiox10010138. 2021.
2. Snehal Shrivastava, Bohan Chen, Lance D Dworkin, Deepak K Malhotra, Rujun Gong*.
Relapse of Nephrotic Syndrome after Adrenocorticotropic Hormone-Induced Remission:
Implications of Adrenocorticotropic Hormone Antibodies.
American Journal of Nephrology 51(5):390-394, 2020.
3. Qiao Y, Wang P, Chang M, Chen B, Ge Y, Malhotra DK, Dworkin LD, Rujun Gong*.
Melanocortin therapy ameliorates podocytopathy and proteinuria in experimental focal
segmental glomerulosclerosis involving a podocyte specific non-MC1R-mediated melanocortinergic
signaling. (Cover Story)
Clinical Science (London). 134(7):695-710, 2020.
5. Xu Y, Guan X, Zhou R, Rujun Gong*.
Melanocortin 5 receptor signaling pathway in health and disease.
Cellular and Molecular Life Sciences 2020 Apr 4. doi: 10.1007/s00018-020-03511-0.
6. Rujun Gong, Wang P, Dworkin L.
7. Rujun Gong*.
Leveraging melanocortin pathways to treat glomerular diseases. [Invited Review]
Advances in Chronic Kidney Disease 21(2):134-151, 2014.
8. Andrew S. Brem, David J. Morris, Xiangpo Li, Yan Ge, Sunil Shaw, Rujun Gong*.
Adrenalectomy amplifies aldosterone induced injury in cardiovascular tissue: An effect
attenuated by adrenally derived steroids.
Steroids 78(3):347-55, 2013.
9. Rujun Gong*.
The renaissance of corticotropin therapy in proteinuric nephropathies.
Nature Reviews Nephrology 8(2):122-8, 2012.
10. Si J, Ge Y, Zhuang S, Wang LJ, Chen S, Rujun Gong*.
Adrenocorticotropic hormone ameliorates acute kidney injury by steroidogenic-dependent
and -independent mechanisms.
Kidney International 2013 Apr;83(4):635-46.
11. Andrew Brem, David Morris, Rujun Gong*.
Aldosterone induced fibrosis in the kidney: Questions and controversies.
American Journal of Kidney Disease 58(3):471-479, 2011.
12. Andrew S. Brem, David J. Morris, Yan Ge, Lance Dworkin, Evelyn Tolbert, Rujun Gong*.
Direct fibrogenic effects of aldosterone on normotensive kidney: An effect modified
by 11b-HSD activity.
American Journal of Physiology Renal Physiology 298(5): F1178-F1187, 2010.
13. Jin Si, Yan Ge, Shougang Zhuang, Rujun Gong*.
Inhibiting nonmuscle myosin II impedes inflammatory infiltration and ameliorates progressive
renal disease.
Laboratory Investigation 90(3): 448-458, 2010.
Featured article with commentary:
Putting the brakes on inflammatory cell motility. Laboratory Investigation
90(3): 346-347, 2010.
14. Rujun Gong*.
Multi-target anti-inflammatory action of hepatocyte growth factor. [Review]
Current Opinion in Investigational Drugs 9(11):1163-1170, 2008.
Chapters in books
- Rujun Gong, Lance D. Dworkin, Barry M. Brenner and David Maddox. The Renal Circulations and Glomerular Ultrafiltration. In: Brenner and Rector's, The Kidney, 8th Edition, Volume 1: 91-129. W.B. Saunders Company, Philadelphia, 2007.
Patents
- Lance D. Dworkin, Rujun Gong. Compositions and Method for Detecting and Treating Renal Injury and Inflammation. U.S. Patent Application No. 11/731,250, March 2007.
- Steve Cartt, Rujun Gong. ACTH Prophylactic Treatment of Renal Disorders. U.S. Patent Application 13/281,175 08/05/2015.