Bioengineering

BIOE 4740 Tissue Engineering

Designation:    Elective
  
Description:    Application of principles from engineering and the life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function.
  
Prerequisite:    BIOE 2200; BIOE 4100
  
Textbook:    Tissue Engineering 
B. Palsson and S. Bhatia 
Prentice Hall
  
Objectives:    The overall aim of this course is to understand the basic principles involved in development and fabrication of artificial cellular materials for the replacement of diseased and aged tissues.
  
Topics:    Morphogenesis 
Cellular Fate Processes 
Coordination of Cellular Fate Processes 
Cell and Tissue Characterization 
Cell and Tissue Properties 
Cell and Tissue Culture 
Cell Culture Demonstration 
Biomaterial Scaffolds 
Tailoring Biomaterials 
Conventional Clinical Approaches 
Host Interaction 
Tissue Engineered Products 
Engineering Methods and Design 
Extracellular matrix Materials 
Extracellular regulation of cell function 
Cell culture and cryopreservation 
Basic immunology and biocompatibility 
Specific tissue requirements 
Progress in generating Engineered Substitutes
  
Schedule:    2 - 1 hour and 15 minute lectures per week
  
Contribution:    Engineering topics
  
Outcomes:   
(a)    An ability to apply knowledge of mathematics, science, and engineering
(e)    An ability to identify, formulate, and solve engineering problems
(8a)    An understanding of biology and physiology
  
Prepared by:    Scott Molitor (scott.molitor@utoledo.edu) and Tammy Phares (tamara.phares@utoledo.edu).
  
Last Updated: 6/27/22