Radiation Biology
UT HSC Medical Physics Course MPHY6160/8160 (CRN: 27965/27971)
Spring semester 2022
| Class meeting time: |
Wednesday 9:30 AM - 12:15 PM
(*Wednesday, 4:30 – 7:15 PM for MH lectures)
|
| Class meeting place: |
Ruppert Center, Suit K, 0005A
(*DCC 2nd floor conference room for MH lectures)
|
| Textbook: |
Radiobiology for the Radiologist, 7th edition
Eric J. Hall, Amato Giaccia; Lippincott, Williams & Wilkins Co, Philadelphia, PA
(the electronic version is available through the UT library)
|
| Instructors: |
Diana Shvydka, E. Ishmael Parsai, Nicholas N. Sperling, Mersiha Hadziahmetovic, Faheem
Ahmad, TBD physician
|
| Grades: |
Midterm - 50%, Final exam - 50% |
Syllabus:
|
Date
|
Prof.
|
Topic(s)
|
Chapters
|
|
19 Jan
|
EIP
|
Physics & Chemistry of Radiation Absorption
|
1
|
|
26 Jan
|
DS
|
DNA Strand Breaks; Chromosome Aberrations; Cell Survival Curves
|
2, 3
|
|
2 Feb
|
DS
|
Radiosensitivity and Cell Age in the Mitotic Cycle; Fractionated Radiation and the
Dose-Rate Effect
|
4, 5
|
| **7 Feb |
FA |
Heritable Effects of Radiation; Effects of Radiation on the Embryo and Fetus |
11, 12 |
|
9 Feb
|
EIP
|
Oxygen Effects; Re-oxygenation; Linear Energy Transfer; Relative Biological Effectiveness
|
6, 7
|
|
16 Feb
|
NNS
|
Effects of Total Body Irradiation; Radiation Cataractogenesis; Radiation Carcinogenesis
|
8, 10, 13
|
|
*2 Mar
|
MH
|
Cancer Biology
|
18
|
|
Week of Mar 9th
|
|
SPRING BREAK
|
|
|
16 Mar
|
DS
|
MIDTERM EXAMINATION
|
1-8, 10-13, 18
|
|
23 Mar
|
DS
|
Dose-Response Relationships; Normal Tissue Responses
|
19, 20
|
|
30 Mar
|
NNS
|
Diagnostic Imaging; Nuclear Medicine; Radiation Risk vs. Benefit; Radiation Protection
|
15, 16, 17
|
|
6 Apr
|
DS
|
Model Tumor Systems; Tumor Kinetics
|
21, 22
|
|
*13 Apr
|
MH
|
Time, Dose and Fractionation in Clinical Radiotherapy; Newer & Less Common Radiation
Modalities
|
23, 24, 25
|
|
*20 Apr
|
TBD
|
Radioprotectors; Radiosensitizers; Chemotherapy Agents
|
9, 26, 27
|
|
27 Apr
|
DS
|
Hyperthermia; Predictive Assays; Radiation and Immunotherapy
|
28
|
|
4 May
|
DS
|
FINAL EXAMINATION
|
9, 15-17, 19-28
|
