Jian-Ting Zhang, Ph.D.
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Jian-Ting Zhang, Ph.D. Professor and Chairman Cancer Biology McMaster Endowed Chair of Biochemistry and Cancer Biology jianting.zhang@utoledo.edu |
EDUCATION:
1979 B.S. Biochemistry Nanjing University
1989 Ph.D. Molecular and Cell Biology State University at New York, Buffalo
1993 Post Doc Cancer Biology University of Toronto
RESEARCH INTERESTS:
The research in Dr. Zhang's laboratory focuses primarily on cancer biology and experimental
therapeutics. In cancer biology, we are investigating how eukaryotic translation initiation
factors are involved in regulating gene expression, signal transduction, cell growth
and differentiation. More specifically, we are interested in the role of eIF3 complex
in Wnt/beta-catenin signaling, tumorigenesis and cancer prognosis. In experimental
therapeutics, we are interested in multiple mechanisms of drug resistance including
studies on ABC transporters, 14-3-sigma, survivin and fatty acid synthase. We also
perform drug discovery research targeting these proteins and various other known targets
using chemoinformatics and rational design.
PUBLICATIONS: