Student-Faculty Publications
PUBLICATIONS
(bold = CCB student, faculty, staff, and alumni)
2026
Becker, K.N., Hagood, M., Creeden, J.F., Heck, H., Haak, P.T., Larder, C., Tipton, C., Schroeder, J. and Eisenmann K.M. (February 18, 2026) Baseline Clinician Attitudes and Practices Regarding Long-Term Neurological Follow-Up for COVID-19 Patients: Early Pandemic Insights With Contemporary Relevance. Cureus 18(2): e103837. DOI 10.7759/cureus.103837
Reddy, MVSSRR, Wood, JF., Norris, J, Becker, K, Murphy, SC, Doddi, S, Imami, A, Ryan, WG, Nguyen, J, Schroeder, J, Eisenmann, K, McCullumsmith, RE (2026) Integrative transcriptomic and perturbagen analyses reveal sex-specific molecular signatures across glioma subtypes. Cancers 18:52. https://doi.org/10.3390/cancers18010052
2025
Becker, K.N., Hagood, M.C., Stuckert, M., Heck, H., Pettee, K., Schroeder, J., Eisenmann, K.M. (2025)Targeting glioblastoma invasion and therapy resistance: Emerging trends and molecular pathways. Tumor Discov. 4:8578. doi: 10.36922/td.8578
Ghai, S., Shrestha, R., Su, K-H. (2025) HSF1 at the crossroads of chemoresistance: from current insights to future horizons in cell death mechanisms. Front Cell Dev Biol. 12:1500880. doi: 10.3389/fcell.2024.1500880
Luo, Y., Biswas, H., Makinwa, Y., Liu, SH., Dong, Z., Liu, JY., Zhang, JT., Zou, Y. (2025) A PP2A-mtATR-tBid axis links DNA damage-induced CIP2A degradation to apoptotic dormancy and therapeutic resistance in PDAC. Cancer Lett. 627:217790. doi: 10.1016/j.canlet.2025.217790.
Schwarz, G., Ren, X., Xie, W., Guo, H., Jiang, Y. and Zhang, J. (2025) Engineered exosomes: a promising drug delivery platform with therapeutic potential. Front. Mol. Biosci. 12:1583992. doi.org/10.3389/fmolb.2025.1583992
Sharma, V., Fernando, V., Zheng, X., Choi, E-S., Sweef, O., Thomas, V., Szpendyk, J., Furuta, S. (2025) Immunogenic shift of arginine metabolism triggers systemic metabolic and immulological reprogramming to suppress HER2+ breast cancer. Cancer Metab. 13:15. https://doi.org/10.1186/s40170-025-00384-4
2024
Barlow, L., Josephraj, S., Gu, B., Dong, Z., Zhang, JT. (2024) FASN negatively regulates the expression of p65 by diminishing its stability through phosphorylation at Thr254 and isomerization by Pin1. J Lipid Res. 65:100529. doi:10.1016/j.jlr.2024.100529
Creeden, J.F., Sevier, J., Zhang, J.T., Lapitsky, Y., Brunicardi, F.C., Jin, G., Nemunaitis, J., Liu, JY., Kalinoski, A., Rao, D., Liu, SH. (2024) Smart exosomes enhance PDAC targeted therapy. J Control Release 368:413-429. doi:10.1016/j.jconrel.2024.02.037
Dreier, M.R., Walia, J., de la Serna, I.L. (2024) Targeting SWI/SNF Complexes in Cancer: An Overview of Pharmacological Strategies and Consequences. Epigenomes. 2024 8:7. doi:10.3390/epigenomes8010007
Fernando, V., Zheng, X., Sharma, V., Sweef, O., Choi, E-S., and Furuta, S. (2024) Reprogramming of Breast Tumor-Associated Macrophages with Modulation of Arginine Metabolism. Life Sci Alliance 7:e202302339. doi: 10.26508/lsa.202302339.
Letson, J., Ren, G., Zheng, X., Sweef, O., Corcino, Y.L., Furuta, S. Reduced S-nitrosylation of TGFβ1 elevates its binding affinity toward the receptor and promotes fibrogenic signaling in the breast. J Biol Chem. 2024 Dec;300(12):108011. doi:10.1016/j.jbc.2024.108011
Liu, R., Zhao, Y., Su, S., Kwabil, A., Njoku, P.C., Yu, H., Li, X. (2024) Unveiling cancer dormancy: Intrinsic mechanisms and extrinsic forces. Cancer Lett. 591:216899. https://doi.org/10.1016/j.canlet.2024.216899
Makinwa, Y., Luo, Y., Musich, P.R., Zou, Y. (2024) Canonical and noncanonical functions of the BH3 domain protein bid in apoptosis, oncogenesis, cancer therapeutics, and aging. Cancers 16:2199. doi:10.3390/cancers16122199
2023
Ahmad, N., de la Serna, I.L., Marathe, H.G., Fan, X., Dube, P., Zhang, S., Haller, S.T., Kennedy, D.J., Pestov, N.B., and Modyanov, N.N. (2023) Eutherian-specific functions of BetaM acquired through Atp1b4 gene co-option in the regulation of MyoD expression. Life (Basel) 13:414. doi: 10.3390/life13020414
Argueta, C.E., Figy, C., Bouali, S., Guo, A., Yeung, K.C., Fenteany, G. (2023) RKIP localizes to the nucleus through a bipartite nuclear localization signal and interaction with importin α to regulate mitotic progression. J. Biol. Chem. 299:103023. https://doi.org/10.1016/j.jbc.2023.103023
Basuroy, T., Dreier, M., Baum, C., Blomquist, T., Trumbly, R., Filipp, F.V., de la Serna, I.L. (2023) Epidgentic and pharmacological control of pigmentatin via Bromodomain Protein 9 (BRD9). Pigment Cell Melanoma Res. 36:19-32. doi: 10.1111/pcmr.13068
Beamer, M.A., Zamora, C., Nestor-Kalinoski, A.L., Fernando, V., Sharma, V., and Furuta, S. (2023) Novel 3D flipwell system that models gut mucosal microenvironment for studying interactions between gut microbiota, epithelia and immunity. Sci .Rep. 13:870. https://doi.org/10.1038/s41598-023-28233-8
Biswas H, Makinwa Y, Zou Y. (2023) Novel cellular functions of ATR for therapeutic targeting: Embryogenesis to tumorigenesis. Int J Mol Sci. Jul20;24(14). Doi:10.3390/ijms241411684
Cui, T, Huang, C, Liu J-Y and Zhang J-T (2023) Small molecule inhibitors targeting the "undruggable" survivin: The past, present, and future from a medicinal chemist's perspective. J Med Chem 66(24): 16515-16545. https://doi.org/10.1021/acs.jmedchem.3c01130
Figy, C., Guo, A., Fernando, V.R., Furuta, S., Al-Mulla, F. , Yeung, K. (2023) Changes in expression of tumor suppressor gene RKIP impact how cancers interact with their complex environment. Cancers (Basel) 15:958. https://doi.org/10.3390/cancers15030958
Ghai, S., Young, A., and Su, K-H. (2023) Proteotoxic stress response in atherosclerotic cardiovascular disease: Emerging role of heat shock factor 1. Front. Cardiovasc. Med. 10:1155444, doi: 10.3389/fcvm.2023.1155444
Gurung, D., Danielson, J.A., Tasnim, A., Zhang, J.T., Zou, Y., Liu, J.Y. (2023) Proline isomerization: From the chemistry and biology to therapeutic opportunities. Biology (Basel) 12(7). doi:10.3390/biology12071008.37508437
Heck, H., Tipton, C. Becker, K., Creeden, J., Schroeder, J., Larder, C., Haak, P., Pyles, B., Eisenmann, K. (2023) Impact of COVID-19 on clinical productivity at the University of Toledo Medical Center Specialty Care Clinics. Translation The University of Toledo Journal of Medical Sciences, 11(2). doi:10.46570
Fernando, V., Zheng, X., Sharma, V., Furuta, S. (2023) Reprogramming of breast tumor-associated macrophages with modulation of arginine metabolism. Preprint. bioRxiv. 2023;2023.08.22.554238. Published 2023 Aug 22. doi:10.1101/2023.08.22.554238
Letson, J., Furuta, S. (2023) Reduced S-nitrosylation of TGFβ1 elevates its binding affinity towards the receptor and promotes fibrogenic signaling in the breast. bioRxiv, 2023 Sep 12:2023.09.07.556714. doi: https://doi.org/10.1101/2023.09.07.556714
Qin, L., Dong, Z., Huang, C., Liu, H., Beebe, J., Subramaniyan, B., Hao, Y., Liu, Y., He, Z., Liu, J-Y., Zhang, J-T. (2023) Reversible promoter demethylation of PDGFD confers gemcitabine resistance through STAT3 activation and RRM1 upregulation. Cancer Lett. 567:216266. doi: 10.1016/j.canlet.2023.216266.
Raman, D., Cimpean, A.M., and De Miglio, M.R. (2023) Editorial: Drug resistance in breast cancer - mechanisms and approaches to overcome chemoresistance. Front Oncol. 12:1080684. doi: 10.3389/fonc.2022.1080684
Zajac, K.K., Malla, S., Babu, R.J., Raman, D., Tiwari, A.K. (2023) Ethnic disparities in the immune microenvironment of triple negative breast cancer and its role in therapeutic outcomes. Cancer Rep (Hoboken). 2023:e1779. doi:10.1002/cnr2.1779