Student-Faculty Publications
PUBLICATIONS
(bold = CAB student or alumni, underline = CAB faculty)
2022
Su, S., Cao, J., Meng, X., Liu, R., Vander Ark, A., Woodford, E., Zhang, R., Stiver, I., Zhang, X., Madaj, Z. B., Bowman, M. J., Wu, Y., Xu, H. E., Chen, B., Yu, H., Li, X. (2022) Enzalutamide-induced and PTH1R-mediated TGFBR2 degradation in osteoblasts confers resistance in prostate cancer bone metastases. Cancer Letters, 525:170-178
Becker, K.N., Eisenmann, K. M. (2022) New Targets in the Glioblastoma Tumor Microtube Multiverse: Emerging Roles for the TGF-beta/TSP1 Signaling Axis Neuro-Oncology, https://doi.org/10.1093/neuonc/noac006
2021
Becker, K.N., Pettee, K.M., Sugrue, A,. Reinard, K.A., Schroeder, J.L., Eisenmann, K.M. (2021) ROCK and mDia have dynamic roles in glioblastoma tumor microtube invasion. Cancer Res. 81:2.
Craig, D.J., Crawford, E.L., Massion, P.P., Morrison, T., Willey, J.C. (2021) Low frequency TP53 mutations in airway epithelial cells serve as lung cancer risk biomarker. Cancer Res. 81:1.
Crawford, E.L., Chen T., Craig, D.J., Willey, J.C. (2021) Use of a synthetic spike-in ladder to measure NGS library complexity. Cancer Res. 81:2.
Creeden, J.F., Imami, A.S., Eby, H.M. Gillman, C., Becker, K.N., Reigle, J., Andari, E., Pan, Z.K., O'Donovan, S.M., McCullumsmith, R.E., and McCullumsmith, C.B. (2021) Fluoxetine as an anti-inflammatory therapy in SARS-CoV-2 infection. Biomed. Pharmacother. 138:111437.
Kalpana, G., Figy, C., Feng, J., Tipton, C., DeCastro, J.N., Bach, V.N., Borile, C., LaSalla, A., Odeh,
H.N., Yeung, M., Garcia-Mata, Yeung, K.C. (2021) The RhoA dependent anti-metastatic function of RKIP in breast cancer. Nature Sci. Rep. 11:17455.
Li ,Z., Hui Wang-Heaton, H., Cartwright, B.M., Makinwa, Y., Hilton, B.A., Musich, P.R., Shkriabai, N., Kvaratskhelia, M.K., Guan, S., Chen,
Q., Yu, X., and Zou, Y. (2021) ATR prevents Ca2+ overload-induced necrotic cell death through phosphorylation-mediated inactivation
of PARP1 without DNA damage signaling. FASEB J 35(5):e21373.
O'Donovan, S.M., Imami, A., Eby, H., Henkel, N.D., Creeden, J.F., Asah, S., Zhang, X., Wu, X., Alnafisah, R., Taylor, R.T., Reigle, J., Thomran, A.,
Shamsaei, B., Meller, J., and McCullumsmith, R.E. (2021) Identification of a candidate repurposable drugs to combat COVID-19 using a signature-based
approach. Scientific Reports, 11(1): 4495.
Ren, G., Zheng, X., Sharma, V., Letson, J., Nestor-Kalinoski, A.L., Furuta, S. (2021) Loss of Nitric Oxide Induces Fibrogenic Response in Organotypic 3D Co-Culture of Mammary Epithelia and Fibroblasts-An Indicator for Breast Carcinogenesis. Cancers. 13. 15
Sharma, V., Fernando, V., Letson, J., Walia, Y., Zheng, X., Fackelman, D., and Furuta, S. (2021) S-Nitrosylation in tumor microenvironment. Int. J. Mol. Sci. 22:(9).
2020
Craig, D.J., Creeden, J.F., Einloth, K.R., Gillman, C.E., Stanbery, L., Hamouda, D., Edelman, G., Dworkin, L., and Nemunaitis, J.J. (2020) Resident memory T cells and their effect on cancer. Vaccines (Basel) 8(4).
Creeden, J.F., Alganem, K., Imami, A.S., Henkel, N.D., Brunicardi, F.C., Liu, S-H., Shukla, R., Tomar, T., Naji F., and Mccullumsmith, R.E. (2020) Emerging kinase therapeutic targets in pancreatic ductal adenocarcinoma and pancreatic
cancer desmoplasia. Int. J. Mol. Sci. 21(22).
Gurung, D., and Blumenthal, R.M. (2020) Distribution of RecBCD and AddAB recombination-associated genes among bacteria in
33 phyla. Microbiology (Reading) 166(11).
Howard, C.M, Estrada, M., Terreo, D., Tiwari, A.K., and Raman, D. (2020) Identification of cardiac glycosides as novel inhibitors of eIF4A1-mediated translation
in triple-negative breast cancer cells. Cancers 12(8).
Makinwa, Y., Musich, P.R., and Zou, Y. (2020) Phosphorylation-Dependent Pin1 isomerization of ATR: Its role in regulating ATR's
anti-apoptotic function at mitochondria, and the implications in cancer. Fron. Cell Dev. Biol. 8:281.
Liu, S-H., Yu, J.H., Creeden, J.F., Sutton, J.M., Markowiak, S., Sanchez, R., Nemunaitis, J., Kalinoski, A., and Zhang, J.T. (2020) Repurposing metformin, simvastatin and digoxin as a combination for targeted therapy
for pancreatic ductal adenocarcinoma. Cancer Lett., 491:97107.
Subramaniyan, B., Sridharan, S., Howard, C.M., Basuroy, T., de la Serna, I., Butt, E., and Raman, D. (2020) Role of the CXCR4-LASP1 axis in the stabilization of Snail1 in triple-negative breast
cancer. Cancers 12(9).
Tilley, A.M.C., Howard, C.M., Sridharan, S., Subramaniyan, B., Bearss, N.R., Alkhalili, S., and Raman, D. (2020) The CXCR4-dependent LASP1-Ago2 interaction in triple-negative breast cancer. Cancers 12(9).
Trivedi, A., Mehrotra, A., Baum, C.E., Lewis, B., Basuroy, T., Blomquist, T., Trumbly, R., Filipp, F.V., Setaluri, V., and de la Serna, I.L. Epigenetics Chromatin. (2020) Bromodomain and extra-terminal domain (BET) proteins regulate melanocyte differentiation. 10;13(1):14. doi: 10.1186/s13072-020-00333-z.
Zheng, X., Fernando, V., Sharma, V., Walia, Y., Letson, J., Furuta, S. (2020) Correction of arginine metabolism with sepiapterin-the precursor of nitric oxide synthase
cofactor BH4-induces immunostimulatory-shift of breast cancer. Biochem. Pharmacol. 113887. doi;10.1016/j.bcp.2020.113887.
Makinwa, Y., Cartwright, B.., Musich, P.R., Li, Z., and Zou, Y. (2020) PP2A Regulates phosphorylation-dependent isomerization of cytoplasmic and mitochondrial-associated ATR by Pin1 in DNA damage responses. Front Cell Dev Biol. 8:281.
2019
Aras, S., Saladi, S.V., Basuroy, T., Marathe, H.G., Lores, P., de la Serna, I.L. (2019) BAF60 mediates interactions between the microphthalmia-associated transcription factor and the BRG1-containing SWI/SNF complex during melanocyte differentiation. J. Cell Physiol. 234:11780-11791.
Basuroy, T., de la Serna, I.L. (2019) SETD7 in cardiomyocyte differentiation and cardiac function. Stem Cell Investig. 6:29, doi: 10.21037/sci.2019.08.01
Datar, I., Kalpana, G., Choi, J., Basuroy, T., Trumbly, R., Arudra, S.K.C., McPhee, M.D., de la Serna, I., Yeung, K.C. (2019) Critical role of miR-10B in B-RafV600E dependent anchorage independent growth and invasion of melanoma cells. PLoS One 17;14(4):e0204387
Du, S., Sarver, J.G., Trabbic, C.J., Erhardt, P.W., Schroering, A., and Maltese, W.A. (2019) 6-MOMIPP, a novel brain-penetrant antimiotic indolyl-chalcone, inhibits glioblastoma
growth and viability. Cancer Chemo. Pharmacol. 83:237-254.
Fernando, V., Zheng, X., Walia, Y., Sharma V., Letson, J. Furuta. S. S-Nitrosylation: An emerging paradigm of redox signaling. Antioxidants (Basel), 2019: 8(9).
Howard, C.M., Bearss, N., Subramaniyan, B., Tilley, A., Sridharan, S., Villa, N., Fraser, C.S., Raman, D. (2019) The CXCR4-LASP1-eIF4F axis promotes translation of oncogenic proteins in triple-negative
breast cancer cells. Front. Oncol. 9:284.
Kalpana, G., Figy, C., Yeung, M., and Yeung, K.C. (2019) Reduced RhoA expression enhances breast cancer metastasis with a concomitant increase
in CCR5 and CXCR4 chemokines signaling. Sci. Rep. 9(1):16351. doi:10.1038/s41598019-52746-w
Li, Z., Mbah, N.E., Overmeyer, J.H., Sarver, J.G., George, S., Trabbic, C.J., Erhardt, P.W., and Maltese, W.A. (2019) The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death)
induced by MOMIPP in glioblastoma. BMS Cancer, 19:77.
Liu, SH., Hong, Y., Markowiak, S., Sanchez, R., Creeden, J., Nemunaitis, J., Kalinoski, A., Willey, J., Erhardt, P., Lee, J, van Dam, M., Brunicardi, F.D. (2019) BIRC5 is a target for molecular imaging and detectionof human pancreatic cancer. Cancer Lett. 457:10-19. doi: 10.1016/j.canlet.2019.04.036
Pettee, K.M., Becker, K.N., Alberts, A.S., Reinard, K.A., Schroeder, J.L., Eisenmann, K.M. (2019) Targeting the mDia formin-assembled cytoskeleton is an effective anti-invasion strategy
in adult high-grade glioma patient-derived neurospheres. Cancers (Basel) 11(3) pii: E392. doi: 10.3390/cancers11030392
Ren, G., Sharma, V., Letson, J., Walia, Y., Fernando, V., and Furuta, S. (2019) Reconstituting breast tissue with organotypic three-dimensional co-culture
of epithelial and stromal cells in discontinuous extracellular matrices. Bio-protocol 9(19): e3392.
Ren, G., Zheng, X., Bommarito, M., Metzger, S., Walia, Y., Leston, J., Schroering, A., Kalinoski, A., Weaver, D., Figy, C., Yeung, K., Furuta, S. (2019) Reduced basal nitric oxide production induces precancerous mammary lesions via ERBB2
and TGFβ. Scientific Reports 9:6688.
Sridharan, S., Howard, C.M., Tilley, A.M.C., Subramaniyan, B., Tiwari, A.K., Ruch, R.J., Raman, D. (2019) Novel and alternative targets against breast cancer stemness to combat chemoresistance. Front. Oncol. 9, doi.org/10.3389/fonc.2019.01003
Sridharan, S., Robeson, M., Basihalli-Tukaramrao, D., Howard, C.M., Subramaniyan, B., Tilley, A.M.C., Tiwari, A.K., and Raman, D. (2019) Targeting the Eukaryotic Translation Initiation Factor 4A Against Breast Cancer Stemness. Front. Oncol., 9:doi: 10.3389/fonc.2019.01311
2018
Datar, I., Kalpana, G., de la Serna, I., Trumbly, R., Choi, J., Yeung, K.C. (2018) Critical role of MiR-10b in BRafV600E dependent anchorage-independent growth and invasion of melanoma cells. BioRxiv https://doi.org/10.1101/413476
Dvorak, K.M., Pettee, K.M., Rubinic-Minotti, K., Su, R., Nestor-Kalinoski, A., Eisenmann, K.M. (2018) Carcinoma-associate fibroblasts (CAFs) promote breast cancer motility by suppressing mammalian Diaphanous-related formin-2 (mDia2). PLos ONE, 13:e0195278.
LeCorgne, H., Tudosie, A.M, Lavik, K., Su, R., Becker, K.N., Moore, S., Walia, Y., Wisner, A., Koehler, D., Alberts, A.S., Williams, F.E. and Eisenmann, K.E. (2018) Differential toxicity of mDia formin-directed functional agonists and antagonists
in developing zebrafish. Fron. Pharmacol. 9: doi:10.3389/fphar.2018.00340.
Marathe, H.M., Watkins-Chow, D.E., Weider, M., Hoffman, A., Mehta, G., Trivedi, A., Aras, S. Basuroy, T., Mehrotra, A., Bennett, D.C., Wegner, M., Pavan, W.J., and de la Serna, I.L. (2017) BRG1 interacts with SOX10 to establish the melanocyte lineage. Nucleic Acids Res. 45:6442-6450.
Li, Z., Mbah, N.E., and Maltese, W.A. (2018) Vacuole-inducing compounds that disrupt endolysosomal trafficking stimulate production
of exosomes by glioblastoma cells. Mol. Cell. Biochem. 439:1-9.
2017
Marathe, H.G., Watkins-Chow, D.E., Weider, M., Hoffmann, A., Mehta, G., Trivedi, A., Aras, S., Basuroy, T., Mehrotra, A., Bennett, D.C., Wegener, M., Pavan, W.J., and de la Serna, I.L. (2017) BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation. Nucleic Acids Res. 45:6442-6458.
Mbah, N., Overmeyer, J.H., and Maltese, W.A. (2017) Disruption of endolysosomal trafficking pathways in glioma cells by methuosis-inducing
indole-based chalcones. Cell Biol. Toxicol. 33:263-282.
Wyse, M.M., Goicoechea, S., Garcia-Mata, R., Nestor-Kalinoski, A.L., and Eisenmann, K.M. (2017) mDia2 and CXCL 12/CXCR4 chemokine signaling intersect to drive tumor cell amoeboid
morphological transition. Biochem. Biophys. Res. Commun. 484: 255-261.
Su, S., Cao, J., Meng, X., Liu, R., Vander Ark, A., Woodford, E., Zhang, R., Stiver, I., Zhang, X., Madaj, Z. B., Bowman, M. J., Wu, Y., Xu, H. E., Chen, B., Yu, H., Li, X.
(2022) Enzalutamide-induced and PTH1R-mediated TGFBR2 degradation in osteoblasts confers resistance in prostate cancer bone metastases. Cancer Letters, 525:170-178
Becker, K.N., Eisenmann, K. M. (2022) New Targets in the Glioblastoma Tumor Microtube Multiverse: Emerging Roles for the TGF-beta/TSP1 Signaling Axis Neuro-Oncology, https://doi.org/10.1093/neuonc/noac006