Department of Cell and Cancer Biology

Student-Faculty Publications


(bold = CAB student or alumni, underline = CAB faculty) 


Becker, K.N., Gifford, C.S., Qaqish, H., Alexander, C., Ren, G., Caras, A., Miller, W.K., Schroeder, J.L. (2022) A Population-Based Study of Patients with Sleep-Wake Disorders Undergoing Elective Instrumented Spinal Surgery. World Neurosurg.

Becker, K.N., Eisenmann, K. M. (2022) New Targets in the Glioblastoma Tumor Microtube Multiverse: Emerging Roles for the TGF-beta/TSP1 Signaling Axis Neuro-Oncology,

Becker, K.N., Pettee, K.M., Sugrue, A., Reinard, K.A., Schroeder, J.L., Eisenmann, K.E.  (2022) The Cytoskeleton Effectors Rho-Kinase (ROCK) and Mammalian Diaphanous-Related (mDia) Formin Have Dynamic Roles in Tumor Microtube Formation in Invasive Glioblastoma Cells. Cells 11:1159

Biswas, H., S. Zhao, Y. Makinwa, J.S. Bassett, M. Pike, P.R. Musich, JY Liu, Y. Zou (2022) Prolyl Isomerization-Mediated Conformational Changes Define ATR Subcellular Compartment-Specific Functions. Front . Cell Dev. Biol. , in press.

Sharma, V., Letson, J., Furuta, S. (2022) Fibrous Stroma: Driver and Passenger Cancer Development.  Sci. Signal. 15. doi: 10.1126/scisignal.abg3449


Becker, K.N., Pettee, K.M., Sugrue, A,. Reinard, K.A., Schroeder, J.L., Eisenmann, K.M. (2021) ROCK and mDia have dynamic roles in glioblastoma tumor microtube invasionCancer Res. 81:2.

Craig, D.J., Crawford, E.L., Massion, P.P., Morrison, T., Willey, J.C. (2021) Low frequency TP53 mutations in airway epithelial cells serve as lung cancer risk biomarker. Cancer Res. 81:1.

Crawford, E.L., Chen T., Craig, D.J., Willey, J.C. (2021) Use of a synthetic spike-in ladder to measure NGS library complexityCancer Res. 81:2.

Creeden, J.F., Imami, A.S., Eby, H.M. Gillman, C., Becker, K.N., Reigle, J., Andari, E., Pan, Z.K., O'Donovan, S.M., McCullumsmith, R.E., and McCullumsmith, C.B. (2021) Fluoxetine as an anti-inflammatory therapy in SARS-CoV-2 infection. Biomed. Pharmacother. 138:111437.

Gardiyawasam, K., Figy, C., Feng, J., Tipton, C., De Castro, J.N., Bach, V.N., Borile, C., LaSalla, A., Odeh, H.N., Yeung, M., Garcia-Mata, R., Yeung, K.C. (2021) The RhoA dependent anti-metastatic function of RKIP in breast cancer. Nature Sci. Rep. 11:17455.

Kalpana, G., Figy, C., Feng, J., Tipton, C., DeCastro, J.N., Bach, V.N., Borile, C., LaSalla, A., Odeh, H.N., Yeung, M., Garcia-Mata, Yeung, K.C. (2021) The RhoA dependent anti-metastatic function of RKIP in breast cancer. Nature Sci. Rep. 11:17455.

Li ,Z., Hui Wang-Heaton, H., Cartwright, B.M., Makinwa, Y., Hilton, B.A., Musich, P.R., Shkriabai, N., Kvaratskhelia, M.K., Guan, S., Chen, Q., Yu, X., and Zou, Y. (2021) ATR prevents Ca2+ overload-induced necrotic cell death through phosphorylation-mediated inactivation of PARP1 without DNA damage signaling. FASEB J  35(5):e21373.

O'Donovan, S.M., Imami, A., Eby, H., Henkel, N.D., Creeden, J.F., Asah, S., Zhang, X., Wu, X., Alnafisah, R., Taylor, R.T., Reigle, J., Thomran, A., Shamsaei, B., Meller, J., and McCullumsmith, R.E. (2021) Identification of a candidate repurposable drugs to combat COVID-19 using a signature-based approach. Scientific Reports, 11(1): 4495.

Ren, G., Zheng, X., Sharma, V., Letson, J., Nestor-Kalinoski, A.L., Furuta, S. (2021) Loss of Nitric Oxide Induces Fibrogenic Response in Organotypic 3D Co-Culture of Mammary Epithelia and Fibroblasts-An Indicator for Breast CarcinogenesisCancers. 13. 15

Sharma, V., Fernando, V., Letson, J., Walia, Y., Zheng, X., Fackelman, D., and Furuta, S. (2021) S-Nitrosylation in tumor microenvironmentInt. J. Mol. Sci. 22:(9).


Craig, D.J., Creeden, J.F., Einloth, K.R., Gillman, C.E., Stanbery, L., Hamouda, D., Edelman, G., Dworkin, L., and Nemunaitis, J.J.  (2020) Resident memory T cells and their effect on cancerVaccines (Basel)  8(4).

Creeden, J.F., Alganem, K., Imami, A.S., Henkel, N.D., Brunicardi, F.C., Liu, S-H., Shukla, R., Tomar, T., Naji F., and Mccullumsmith, R.E. (2020) Emerging kinase therapeutic targets in pancreatic ductal adenocarcinoma and pancreatic cancer desmoplasia. Int. J. Mol. Sci. 21(22).

Gurung, D., and Blumenthal, R.M. (2020) Distribution of RecBCD and AddAB recombination-associated genes among bacteria in 33 phylaMicrobiology (Reading) 166(11).

Howard, C.M, Estrada, M., Terreo, D., Tiwari, A.K., and Raman, D. (2020) Identification of cardiac glycosides as novel inhibitors of eIF4A1-mediated translation in triple-negative breast cancer cells. Cancers 12(8).

Makinwa, Y., Musich, P.R., and Zou, Y. (2020) Phosphorylation-Dependent Pin1 isomerization of ATR: Its role in regulating ATR's anti-apoptotic function at mitochondria, and the implications in cancer. Fron. Cell Dev. Biol. 8:281.

Liu, S-H., Yu, J.H., Creeden, J.F., Sutton, J.M., Markowiak, S., Sanchez, R., Nemunaitis, J., Kalinoski, A., and Zhang, J.T. (2020) Repurposing metformin, simvastatin and digoxin as a combination for targeted therapy for pancreatic ductal adenocarcinoma. Cancer Lett., 491:97107.

Subramaniyan, B., Sridharan, S., Howard, C.M., Basuroy, T., de la Serna, I., Butt, E., and Raman, D. (2020) Role of the CXCR4-LASP1 axis in the stabilization of Snail1 in triple-negative breast cancer. Cancers 12(9).

Tilley, A.M.C., Howard, C.M., Sridharan, S., Subramaniyan, B., Bearss, N.R., Alkhalili, S., and Raman, D. (2020) The CXCR4-dependent LASP1-Ago2 interaction in triple-negative breast cancer. Cancers 12(9).

Trivedi, A.,
Mehrotra, A., Baum, C.E., Lewis, B., Basuroy, T., Blomquist, T., Trumbly, R., Filipp, F.V., Setaluri, V., and de la Serna, I.L. Epigenetics Chromatin. (2020)  Bromodomain and extra-terminal domain (BET) proteins regulate melanocyte differentiation. 10;13(1):14. doi: 10.1186/s13072-020-00333-z.

Zheng, X., Fernando, V., Sharma, V., Walia, Y., Letson, J., Furuta, S. (2020) Correction of arginine metabolism with sepiapterin-the precursor of nitric oxide synthase cofactor BH4-induces immunostimulatory-shift of breast cancer. Biochem. Pharmacol. 113887. doi;10.1016/j.bcp.2020.113887.

Makinwa, Y., Cartwright, B.., Musich, P.R., Li, Z., and Zou, Y. (2020) PP2A Regulates phosphorylation-dependent isomerization of cytoplasmic and mitochondrial-associated ATR by Pin1 in DNA damage responses. Front Cell Dev Biol. 8:281.


Aras, S., Saladi, S.V., Basuroy, T., Marathe, H.G., Lores, P., de la Serna, I.L. (2019) BAF60 mediates interactions between the microphthalmia-associated transcription factor and the BRG1-containing SWI/SNF complex during melanocyte differentiation. J. Cell Physiol. 234:11780-11791.

Basuroy, T., de la Serna, I.L. (2019) SETD7 in cardiomyocyte differentiation and cardiac function. Stem Cell Investig. 6:29, doi: 10.21037/sci.2019.08.01

Datar, I., Kalpana, G.,
Choi, J., Basuroy, T., Trumbly, R., Arudra, S.K.C., McPhee, M.D., de la Serna, I., Yeung, K.C. (2019) Critical role of miR-10B in B-RafV600E dependent anchorage independent growth and invasion of melanoma cells. PLoS One 17;14(4):e0204387

Du, S., Sarver, J.G., Trabbic, C.J., Erhardt, P.W., Schroering, A., and Maltese, W.A. (2019) 6-MOMIPP, a novel brain-penetrant antimiotic indolyl-chalcone, inhibits glioblastoma growth and viability. Cancer Chemo. Pharmacol. 83:237-254.

Fernando, V., Zheng, X., Walia, Y., Sharma V., Letson, J. Furuta. S.  S-Nitrosylation: An emerging paradigm of redox signaling. Antioxidants (Basel), 2019: 8(9).

Howard, C.M.,
Bearss, N., Subramaniyan, B., Tilley, A., Sridharan, S., Villa, N., Fraser, C.S., Raman, D. (2019) The CXCR4-LASP1-eIF4F axis promotes translation of oncogenic proteins in triple-negative breast cancer cells. Front. Oncol. 9:284.

Kalpana, G., Figy, C., Yeung, M., and Yeung, K.C. (2019) Reduced RhoA expression enhances breast cancer metastasis with a concomitant increase in CCR5 and CXCR4 chemokines signaling. Sci. Rep. 9(1):16351. doi:10.1038/s41598019-52746-w 

Li, Z., Mbah, N.E., Overmeyer, J.H., Sarver, J.G., George, S., Trabbic, C.J., Erhardt, P.W., and Maltese, W.A. (2019) The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastoma. BMS Cancer, 19:77.

Liu, SH., Hong, Y., Markowiak, S., Sanchez, R., Creeden, J., Nemunaitis, J., Kalinoski, A., Willey, J., Erhardt, P., Lee, J, van Dam, M., Brunicardi, F.D. (2019) BIRC5 is a target for molecular imaging and detectionof human pancreatic cancer. Cancer Lett. 457:10-19. doi: 10.1016/j.canlet.2019.04.036

Pettee, K.M., Becker, K.N., Alberts, A.S., Reinard, K.A., Schroeder, J.L., Eisenmann, K.M. (2019) Targeting the mDia formin-assembled cytoskeleton is an effective anti-invasion strategy in adult high-grade glioma patient-derived neurospheres. Cancers (Basel) 11(3) pii: E392. doi: 10.3390/cancers11030392

Ren, G., Sharma, V., Letson, J., Walia, Y., Fernando, V., and Furuta, S. (2019) Reconstituting breast tissue with organotypic three-dimensional co-culture of epithelial and stromal cells in discontinuous extracellular matrices. Bio-protocol  9(19): e3392.

Ren, G., Zheng, X., Bommarito, M., Metzger, S., Walia, Y., Leston, J., Schroering, A., Kalinoski, A., Weaver, D., Figy, C., Yeung, K., Furuta, S. (2019) Reduced basal nitric oxide production induces precancerous mammary lesions via ERBB2 and TGFβ. Scientific Reports 9:6688.

Sridharan, S., Howard, C.M., Tilley, A.M.C., Subramaniyan, B., Tiwari, A.K., Ruch, R.J., Raman, D. (2019) Novel and alternative targets against breast cancer stemness to combat chemoresistance Front. Oncol. 9,

Sridharan, S., Robeson, M., Basihalli-Tukaramrao, D., Howard, C.M., Subramaniyan, B., Tilley, A.M.C., Tiwari, A.K., and Raman, D. (2019) Targeting the Eukaryotic Translation Initiation Factor 4A Against Breast Cancer Stemness. Front. Oncol., 9:doi: 10.3389/fonc.2019.01311 


Datar, I., Kalpana, G., de la Serna, I., Trumbly, R., Choi, J., Yeung, K.C. (2018) Critical role of MiR-10b in BRafV600E dependent anchorage-independent growth and invasion of melanoma cells. BioRxiv

Dvorak, K.M., Pettee, K.M., Rubinic-Minotti, K., Su, R., Nestor-Kalinoski, A., Eisenmann, K.M. (2018) Carcinoma-associate fibroblasts (CAFs) promote breast cancer motility by suppressing mammalian Diaphanous-related formin-2 (mDia2). PLos ONE, 13:e0195278.

LeCorgne, H., Tudosie, A.M, Lavik, K., Su, R., Becker, K.N., Moore, S., Walia, Y., Wisner, A., Koehler, D., Alberts, A.S., Williams, F.E. and Eisenmann, K.E. (2018) Differential toxicity of mDia formin-directed functional agonists and antagonists in developing zebrafish.  Fron. Pharmacol. 9: doi:10.3389/fphar.2018.00340.

Marathe, H.M., Watkins-Chow, D.E., Weider, M., Hoffman, A., Mehta, G., Trivedi, A., Aras, S. Basuroy, T., Mehrotra, A., Bennett, D.C., Wegner, M., Pavan, W.J., and de la Serna, I.L. (2017) BRG1 interacts with SOX10 to establish the melanocyte lineage. Nucleic Acids Res. 45:6442-6450.

Li, Z., Mbah, N.E.,
  and Maltese, W.A. (2018) Vacuole-inducing compounds that disrupt endolysosomal trafficking stimulate production of exosomes by glioblastoma cells. Mol. Cell. Biochem. 439:1-9.


Last Updated: 6/21/22