Student-Faculty Publications
PUBLICATIONS
(bold = CAB student or alumni, underline = CAB faculty)
2020
Trivedi, A., Mehrotra, A., Baum, C.E., Lewis, B., Basuroy, T., Blomquist, T., Trumbly, R., Filipp, F.V., Setaluri, V., and de la Serna, I.L. Epigenetics Chromatin. (2020) Bromodomain and extra-terminal domain (BET) proteins regulate melanocyte differentiation. 10;13(1):14. doi: 10.1186/s13072-020-00333-z.
Zheng, X., Fernando, V., Sharma, V., Walia, Y., Letson, J., Furuta, S. (2020) Correction of arginine metabolism with sepiapterin-the precursor of nitric oxide synthase
cofactor BH4-induces immunostimulatory-shift of breast cancer. biochem. Pharmacol. 113887. doi;10.1016/j.bcp.2020.113887.
2019
Aras, S., Saladi, S.V., Basuroy, T., Marathe, H.G., Lores, P., de la Serna, I.L. (2019) BAF60 mediates interactions between the microphthalmia-associated transcription factor and the BRG1-containing SWI/SNF complex during melanocyte differentiation. J. Cell Physiol. 234:11780-11791.
Basuroy, T., de la Serna, I.L. (2019) SETD7 in cardiomyocyte differentiation and cardiac function. Stem Cell Investig. 6:29, doi: 10.21037/sci.2019.08.01
Datar, I., Kalpana, G., Choi, J., Basuroy, T., Trumbly, R., Arudra, S.K.C., McPhee, M.D., de la Serna, I., Yeung, K.C. (2019) Critical role of miR-10B in B-RafV600E dependent anchorage independent growth and invasion of melanoma cells. PLoS One 17;14(4):e0204387
Du, S., Sarver, J.G., Trabbic, C.J., Erhardt, P.W., Schroering, A., and Maltese, W.A. (2019) 6-MOMIPP, a novel brain-penetrant antimiotic indolyl-chalcone, inhibits glioblastoma
growth and viability. Cancer Chemo. Pharmacol. 83:237-254.
Fernando, V., Zheng, X., Walia, Y., Sharma V., Letson, J. Furuta. S. S-Nitrosylation: An emerging paradigm of redox signaling. Antioxidants (Basel), 2019: 8(9).
Howard, C.M., Bearss, N., Subramaniyan, B., Tilley, A., Sridharan, S., Villa, N., Fraser, C.S., Raman, D. (2019) The CXCR4-LASP1-eIF4F axis promotes translation of oncogenic proteins in triple-negative
breast cancer cells. Front. Oncol. 9:284.
Kalpana, G., Figy, C., Yeung, M., and Yeung, K.C. (2019) Reduced RhoA expression enhances breast cancer metastasis with a concomitant increase
in CCR5 and CXCR4 chemokines signaling. Sci. Rep. 9(1):16351. doi:10.1038/s41598019-52746-w
Li, Z., Mbah, N.E., Overmeyer, J.H., Sarver, J.G., George, S., Trabbic, C.J., Erhardt, P.W., and Maltese, W.A. (2019) The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death)
induced by MOMIPP in glioblastoma. BMS Cancer, 19:77.
Liu, SH., Hong, Y., Markowiak, S., Sanchez, R., Creeden, J., Nemunaitis, J., Kalinoski, A., Willey, J., Erhardt, P., Lee, J, van Dam, M., Brunicardi, F.D. (2019) BIRC5 is a target for molecular imaging and detectionof human pancreatic cancer. Cancer Lett. 457:10-19. doi: 10.1016/j.canlet.2019.04.036
Pettee, K.M., Becker, K.N., Alberts, A.S., Reinard, K.A., Schroeder, J.L., Eisenmann, K.M. (2019) Targeting the mDia formin-assembled cytoskeleton is an effective anti-invasion strategy
in adult high-grade glioma patient-derived neurospheres. Cancers (Basel) 11(3) pii: E392. doi: 10.3390/cancers11030392
Ren, G., Sharma, V., Letson, J., Walia, Y., Fernando, V., and Furuta, S. (2019) Reconstituting breast tissue with organotypic three-dimensional co-culture
of epithelial and stromal cells in discontinuous extracellular matrices. Bio-protocol 9(19): e3392.
Ren, G., Zheng, X., Bommarito, M., Metzger, S., Walia, Y., Leston, J., Schroering, A., Kalinoski, A., Weaver, D., Figy, C., Yeung, K., Furuta, S. (2019) Reduced basal nitric oxide production induces precancerous mammary lesions via ERBB2
and TGFβ. Scientific Reports 9:6688.
Sridharan, S., Howard, C.M., Tilley, A.M.C., Subramaniyan, B., Tiwari, A.K., Ruch, R.J., Raman, D. (2019) Novel and alternative targets against breast cancer stemness to combat chemoresistance. Front. Oncol. 9, doi.org/10.3389/fonc.2019.01003
Sridharan, S., Robeson, M., Basihalli-Tukaramrao, D., Howard, C.M., Subramaniyan, B., Tilley, A.M.C., Tiwari, A.K., and Raman, D. (2019) Targeting the Eukaryotic Translation Initiation Factor 4A Against Breast Cancer Stemness. Front. Oncol., 9:doi: 10.3389/fonc.2019.01311
2018
Datar, I., Kalpana, G., de la Serna, I., Trumbly, R., Choi, J., Yeung, K.C. (2018) Critical role of MiR-10b in BRafV600E dependent anchorage-independent growth and invasion of melanoma cells. BioRxiv https://doi.org/10.1101/413476
Dvorak, K.M., Pettee, K.M., Rubinic-Minotti, K., Su, R., Nestor-Kalinoski, A., Eisenmann, K.M. (2018) Carcinoma-associate fibroblasts (CAFs) promote breast cancer motility by suppressing mammalian Diaphanous-related formin-2 (mDia2). PLos ONE, 13:e0195278.
LeCorgne, H., Tudosie, A.M, Lavik, K., Su, R., Becker, K.N., Moore, S., Walia, Y., Wisner, A., Koehler, D., Alberts, A.S., Williams, F.E. and Eisenmann, K.E. (2018) Differential toxicity of mDia formin-directed functional agonists and antagonists
in developing zebrafish. Fron. Pharmacol. 9: doi:10.3389/fphar.2018.00340.
Marathe, H.M., Watkins-Chow, D.E., Weider, M., Hoffman, A., Mehta, G., Trivedi, A., Aras, S. Basuroy, T., Mehrotra, A., Bennett, D.C., Wegner, M., Pavan, W.J., and de la Serna, I.L. (2017) BRG1 interacts with SOX10 to establish the melanocyte lineage. Nucleic Acids Res. 45:6442-6450.
Li, Z., Mbah, N.E., and Maltese, W.A. (2018) Vacuole-inducing compounds that disrupt endolysosomal trafficking stimulate production
of exosomes by glioblastoma cells. Mol. Cell. Biochem. 439:1-9.
2017
Marathe, H.G., Watkins-Chow, D.E., Weider, M., Hoffmann, A., Mehta, G., Trivedi, A., Aras, S., Basuroy, T., Mehrotra, A., Bennett, D.C., Wegener, M., Pavan, W.J., and de la Serna, I.L. (2017) BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation. Nucleic Acids Res. 45:6442-6458.
Mbah, N., Overmeyer, J.H., and Maltese, W.A. (2017) Disruption of endolysosomal trafficking pathways in glioma cells by methuosis-inducing
indole-based chalcones. Cell Biol. Toxicol. 33:263-282.
Wyse, M.M., Goicoechea, S., Garcia-Mata, R., Nestor-Kalinoski, A.L., and Eisenmann, K.M. (2017) mDia2 and CXCL 12/CXCR4 chemokine signaling intersect to drive tumor cell amoeboid
morphological transition. Biochem. Biophys. Res. Commun. 484: 255-261.
2016
Datar, I., Qiu, X., Ma, H.Z., Yeung, M., Aras, S., de la Serna, I., Al-Mulla, F., Thiery, J.P., Trumbly, R., Fan, X, Cui, H., and Yeung, K.C. (2016) RKIP regulates CCL5 expression to inhibit breast cancer invasion and metastasis by
controlling macrophage infiltration. Oncotarget 6:39050-39061.
Mbah, N.E., Overmeyer, J.H., and Maltese, W.A. (2016) Disruption of endolysosomal trafficking pathways in glioma cells by methuosis-inducing indole-based
chalcones. Cell Biol. Toxicol. Epub ahead of print DOI:10.1007/s10565-016-9369-2
Trabbic, C.J., George, S.M., Alexander, E.M., Du, S., Offenbacher, J.M., Crissman, E.J., Overmeyer, J.H., Maltese, W.A., and Erhardt, P.W. (2016) Synthesis and biological evaluation of isomeric methoxy substitutions on anti-cancer
indolylpyridinyl-propenones: effects on potency and mode of activity. Eur. J. Med. Chem. 122:79-91.
Ziske, M.A., Pettee, K.M., MaNada, K., Rubinic, K., and Eisenmann, K.M. (2016) SMIFH2-mediated mDia formin functional inhibition potentiates chemotherapeutic targeting
of human ovarian cancer spheroids. Biochem. Biophys. Res. Comm. 472:33-39.