Department of Cancer Biology

Student-Faculty Publications


(bold = CAB student or alumni, underline = CAB faculty) 


Trivedi, A., Mehrotra, A., Baum, C.E., Lewis, B., Basuroy, T., Blomquist, T., Trumbly, R., Filipp, F.V., Setaluri, V., and de la Serna, I.L. Epigenetics Chromatin. (2020)  Bromodomain and extra-terminal domain (BET) proteins regulate melanocyte differentiation. 10;13(1):14. doi: 10.1186/s13072-020-00333-z.

Zheng, X., Fernando, V., Sharma, V., Walia, Y., Letson, J., Furuta, S. (2020) Correction of arginine metabolism with sepiapterin-the precursor of nitric oxide synthase cofactor BH4-induces immunostimulatory-shift of breast cancer. biochem. Pharmacol. 113887. doi;10.1016/j.bcp.2020.113887.


Aras, S., Saladi, S.V., Basuroy, T., Marathe, H.G., Lores, P., de la Serna, I.L. (2019) BAF60 mediates interactions between the microphthalmia-associated transcription factor and the BRG1-containing SWI/SNF complex during melanocyte differentiation. J. Cell Physiol. 234:11780-11791.

Basuroy, T., de la Serna, I.L. (2019) SETD7 in cardiomyocyte differentiation and cardiac function. Stem Cell Investig. 6:29, doi: 10.21037/sci.2019.08.01

Datar, I., Kalpana, G.,
Choi, J., Basuroy, T., Trumbly, R., Arudra, S.K.C., McPhee, M.D., de la Serna, I., Yeung, K.C. (2019) Critical role of miR-10B in B-RafV600E dependent anchorage independent growth and invasion of melanoma cells. PLoS One 17;14(4):e0204387

Du, S., Sarver, J.G., Trabbic, C.J., Erhardt, P.W., Schroering, A., and Maltese, W.A. (2019) 6-MOMIPP, a novel brain-penetrant antimiotic indolyl-chalcone, inhibits glioblastoma growth and viability. Cancer Chemo. Pharmacol. 83:237-254.

Fernando, V., Zheng, X., Walia, Y., Sharma V., Letson, J. Furuta. S.  S-Nitrosylation: An emerging paradigm of redox signaling. Antioxidants (Basel), 2019: 8(9).

Howard, C.M.,
Bearss, N., Subramaniyan, B., Tilley, A., Sridharan, S., Villa, N., Fraser, C.S., Raman, D. (2019) The CXCR4-LASP1-eIF4F axis promotes translation of oncogenic proteins in triple-negative breast cancer cells. Front. Oncol. 9:284.

Kalpana, G., Figy, C., Yeung, M., and Yeung, K.C. (2019) Reduced RhoA expression enhances breast cancer metastasis with a concomitant increase in CCR5 and CXCR4 chemokines signaling. Sci. Rep. 9(1):16351. doi:10.1038/s41598019-52746-w 

Li, Z., Mbah, N.E., Overmeyer, J.H., Sarver, J.G., George, S., Trabbic, C.J., Erhardt, P.W., and Maltese, W.A. (2019) The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastoma. BMS Cancer, 19:77.

Liu, SH., Hong, Y., Markowiak, S., Sanchez, R., Creeden, J., Nemunaitis, J., Kalinoski, A., Willey, J., Erhardt, P., Lee, J, van Dam, M., Brunicardi, F.D. (2019) BIRC5 is a target for molecular imaging and detectionof human pancreatic cancer. Cancer Lett. 457:10-19. doi: 10.1016/j.canlet.2019.04.036

Pettee, K.M., Becker, K.N., Alberts, A.S., Reinard, K.A., Schroeder, J.L., Eisenmann, K.M. (2019) Targeting the mDia formin-assembled cytoskeleton is an effective anti-invasion strategy in adult high-grade glioma patient-derived neurospheres. Cancers (Basel) 11(3) pii: E392. doi: 10.3390/cancers11030392

Ren, G., Sharma, V., Letson, J., Walia, Y., Fernando, V., and Furuta, S. (2019) Reconstituting breast tissue with organotypic three-dimensional co-culture of epithelial and stromal cells in discontinuous extracellular matrices. Bio-protocol  9(19): e3392.

Ren, G., Zheng, X., Bommarito, M., Metzger, S., Walia, Y., Leston, J., Schroering, A., Kalinoski, A., Weaver, D., Figy, C., Yeung, K., Furuta, S. (2019) Reduced basal nitric oxide production induces precancerous mammary lesions via ERBB2 and TGFβ. Scientific Reports 9:6688.

Sridharan, S., Howard, C.M., Tilley, A.M.C., Subramaniyan, B., Tiwari, A.K., Ruch, R.J., Raman, D. (2019) Novel and alternative targets against breast cancer stemness to combat chemoresistance Front. Oncol. 9,

Sridharan, S., Robeson, M., Basihalli-Tukaramrao, D., Howard, C.M., Subramaniyan, B., Tilley, A.M.C., Tiwari, A.K., and Raman, D. (2019) Targeting the Eukaryotic Translation Initiation Factor 4A Against Breast Cancer Stemness. Front. Oncol., 9:doi: 10.3389/fonc.2019.01311



Datar, I., Kalpana, G., de la Serna, I., Trumbly, R., Choi, J., Yeung, K.C. (2018) Critical role of MiR-10b in BRafV600E dependent anchorage-independent growth and invasion of melanoma cells. BioRxiv

Dvorak, K.M., Pettee, K.M., Rubinic-Minotti, K., Su, R., Nestor-Kalinoski, A., Eisenmann, K.M. (2018) Carcinoma-associate fibroblasts (CAFs) promote breast cancer motility by suppressing mammalian Diaphanous-related formin-2 (mDia2). PLos ONE, 13:e0195278.

LeCorgne, H., Tudosie, A.M, Lavik, K., Su, R., Becker, K.N., Moore, S., Walia, Y., Wisner, A., Koehler, D., Alberts, A.S., Williams, F.E. and Eisenmann, K.E. (2018) Differential toxicity of mDia formin-directed functional agonists and antagonists in developing zebrafish.  Fron. Pharmacol. 9: doi:10.3389/fphar.2018.00340.

Marathe, H.M., Watkins-Chow, D.E., Weider, M., Hoffman, A., Mehta, G., Trivedi, A., Aras, S. Basuroy, T., Mehrotra, A., Bennett, D.C., Wegner, M., Pavan, W.J., and de la Serna, I.L. (2017) BRG1 interacts with SOX10 to establish the melanocyte lineage. Nucleic Acids Res. 45:6442-6450.

Li, Z., Mbah, N.E.,
  and Maltese, W.A. (2018) Vacuole-inducing compounds that disrupt endolysosomal trafficking stimulate production of exosomes by glioblastoma cells. Mol. Cell. Biochem. 439:1-9.


Marathe, H.G., Watkins-Chow, D.E., Weider, M., Hoffmann, A., Mehta, G., Trivedi, A., Aras, S., Basuroy, T., Mehrotra, A., Bennett, D.C., Wegener, M., Pavan, W.J., and de la Serna, I.L. (2017) BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation.  Nucleic Acids Res. 45:6442-6458. 

Mbah, N., Overmeyer, J.H., and Maltese, W.A. (2017) Disruption of endolysosomal trafficking pathways in glioma cells by methuosis-inducing indole-based chalcones. Cell Biol. Toxicol. 33:263-282.

Wyse, M.M., Goicoechea, S., Garcia-Mata, R., Nestor-Kalinoski, A.L., and Eisenmann, K.M. (2017) mDia2 and CXCL 12/CXCR4 chemokine signaling intersect to drive tumor cell amoeboid morphological transition.  Biochem. Biophys. Res. Commun. 484: 255-261.


Datar, I.,  Qiu, X., Ma, H.Z., Yeung, M., Aras, S., de la Serna, I., Al-Mulla, F., Thiery, J.P., Trumbly, R., Fan, X, Cui, H., and Yeung, K.C. (2016) RKIP regulates CCL5 expression to inhibit breast cancer invasion and metastasis by controlling macrophage infiltration.  Oncotarget 6:39050-39061.

Mbah, N.E.,
 Overmeyer, J.H., and Maltese, W.A.  (2016) Disruption of endolysosomal trafficking pathways in glioma cells by methuosis-inducing indole-based chalcones.  Cell Biol. Toxicol. Epub ahead of print DOI:10.1007/s10565-016-9369-2

Trabbic, C.J., George, S.M., Alexander, E.M., Du, S., Offenbacher, J.M., Crissman, E.J., Overmeyer, J.H., Maltese, W.A., and Erhardt, P.W. (2016) Synthesis and biological evaluation of isomeric methoxy substitutions on anti-cancer indolylpyridinyl-propenones: effects on potency and mode of activityEur. J. Med. Chem. 122:79-91.

Ziske, M.A., Pettee, K.M., MaNada, K., Rubinic, K., and Eisenmann, K.M.  (2016) SMIFH2-mediated mDia formin functional inhibition potentiates chemotherapeutic targeting of human ovarian cancer spheroids. Biochem. Biophys. Res. Comm. 472:33-39.

Last Updated: 5/26/20