Neurology Research Day
Friday, February 23, 2024
8:30 a.m. to 4 p.m.
ProMedica Neurosciences Center
2130 W. Central Ave, 2nd floor
Rooms 2011 & 2012
2024 Keynote Speaker:
Title: Modeling Genetic Epilepsies with Human brain Organoids
Jack Parent, M.D.
Objectives:
1.) Describe the advantages and limitations of modeling neurological disorders using human brain organoids.
2.) Discuss the use of human brain organoids for exploring epilepsy-associated malformations of cortical devlopment.
3.) Describe the role of genetic mosaicism in the pathogenesis of Protocadherin 19 Clustering Epilepsy.
Jack M. Parent, MD, is a professor of neurology, director of the Neurodevelopment and Regeneration Laboratory, and co-director of the Comprehensive Epilepsy Center in the University of Michigan Medical School.
His current research interests include neural stem cell transplantation to treat brain injury and neurodegeneration, and the modification of adult neural stem cells to promote brain repair after stroke or prevent epilepsy.
Dr. Parent earned a Bachelor of Arts degree, with distinction, in human biology from Stanford University and his medical degree from the Yale University School of Medicine. He completed a medical internship and neurology residency at the University of California, San Francisco (UCSF), where he was selected chief resident. He stayed at UCSF for clinical fellowship training in epilepsy and clinical neurophysiology, and postdoctoral training in neuroscience research.
An internationally recognized research leader in the fields of neural stem cell biology, regeneration after brain injury and epilepsy, Dr. Parent established the Neurodevelopment and Regeneration Laboratory at the University of Michigan in 2000.
Dr. Parent is a member of the Epilepsy Foundation of America Research Council, the Medical Advisory Board of the Global Ischemia Foundation, the Independent Science Review Panel of the New Jersey Commission on Brain Injury Research, and the National Scientific Advisory Council of the American Federation for Aging Research. He also serves as an associate editor of Neuroscience Letters and is on the editorial boards of Experimental Neurology and Epilepsy Currents.
He has received several awards for his research, including a Junior Investigator Award from the American Epilepsy Society, a Paul Beeson Physician Faculty Scholars in Aging Award, a Dreifuss-Penry Epilepsy Award from the American Academy of Neurology, and a Grass Foundation Award in Neuroscience from the American Neurological Association.
Day at a Glance
8:30 – 8:55 AM Breakfast
9:00 – 9:05 AM Opening Remarks – Noor Pirzada, MD
9:10 – 9:55 AM Platform Presentations
9:10 – 9:30 Sidra Saleem, MD
9:35 – 9:55 Dipesh Pokharel, PhD, nnd
10:00 – 11:10 AM Keynote Speaker - Jack M. Parent, MD
11:15 – 11:30 AM Neurology Jeopardy
11:30 – 12:30 PM Lunch
12:35 – 1:20 PM Platform Presentations
12:35 – 12:55 PM Adam Mierzwa, MD
1:00 – 1:20 PM Sidra Saleem, MD
1:25 – 3:00 PM Poster Viewing/Judging
3:00 – 3:30 PM Awards/Closing Remarks
2024 Platform Presentations
2024 Platform Winner:
Thrombectomy Outcomes in Acute Basilar Artery Occlusions Due to Intracranial Atherosclerotic
Disease
Adam Mierzwa, MD, Sami Al Kasab, MD, Ashley Nelson, DO, Santiago Ortega Gutierrez,
MD, Juan Vivanco-Suarez, MD, Mudassir Farooqui, MD, Ashutosh P Jadhav, MD, PhD, Sheshvat
Desai, MD, Gabor Toth, MD, Anas Alrohimi, MD, Thanh N. Nguyen, MD, Piers Klein, MA,
Mohamad Abdalkader, MD, Hisham Salahuddin, MD, Aditya Pandey, MD, Sravanthi Koduri,
MD, Zachary Wilseck, MD, Nirav Vora, MD, Nameer Aladamat, MD, Khaled Gharaibeh, MD,
Ehad Afreen, MD, Syed F. Zaidi, MD, Mouhammad Jumaa, MD
Presenter: Adam Mierzwa, MD
Post-Stroke Seizures; Clinical, Electrographic, Radiologic Characteristics and Management
Options
Sidra Saleem, MD, Hira Pervez, MD, Ajaz Sheikh, MD, Vicki A. Ramsey-Williams, MD,
PhD, Hongyan Li, MD, PhD, Imran Ali, MD
Presented by: Sidra Saleem, MD
Neurofascin 155 IgG4-Associated CIDP: Characterization of Clinical Phenotypes and
Durability of Rituximab Therapy
Authors: Sidra Saleem, MD, Khaled Gharaibeh, MD, Judy Zheng, MD, Zainab Zahra, MD,
Bashar Saour, MD
Presented by: Sidra Saleem, MD
Squalamine as a Potential Neuroprotective Agent in Parkinson's Disease-Related Cognitive
Decline
Dipesh Pokharel, BS, Tatiana White, MS, Vaibhavi Peshattiwar, PhD, Caroline Swain,
BS, MS, Khoi Le, MS, Thyagarajan Subramanian, MD
Presenter: Dipesh Pokharel, BS, & Caroline Swain, MD, PhD
2024 Poster Presentations
2024 Poster Winner:
S129-alphaSyn Phosphorylation in Paraquat and Lectin Model of Parkinson's Disease
Presented by: Caroline Swain, BS, MS
Nigrovagal Chemogentic Inhibition Effects on Paraquat + Lectin Model and Electrophysiology
of the Hemiparkinsonian Substantia Nigra
Presented by: Julia Kalbus
Early Onset Parkinson's Disease Patients with Rem Behavioral Disorder and Constipation
Show Poor Performance on the Mental Rotation Task
Presented by: Joyeta Razzaque, MD
Early and Late Basilar Artery Thrombectomy Time Window Outcomes
Presented by: Adam Mierzwa, MD
Blood Pressure after Successful Endovascular Therapy: A Systematic Review and Meta-Analysis
of Randomized Control Trials
Presented by: Khaled Gharaibeh, MD
Expression of Light Chain 3b (LC3b) in the Mesolimbic Dopaminergic Regions of Rat
Brains Self-administering high Dose Cocaine
Presented by: Sachi Bhati, BS
Triglyceride-HDL Index as a Predictor of Post-Stroke Cardiovascular Outcomes: Analysis
of 6,235 Stroke Patients from the Qatar Stroke Database
Presented by: Syed M. Owais, MD
Targeted Hemispheric Lesioning with 6-OHDA
Presented by: Tatiana White, MS
Word Reading in Persons with Epilepsy Using the Wide Range Achievement Test-4 (WRAT-4)
Presented by: Fahham Asghar, MD
Understanding the Mechanisms of Brain Dysfunction when Performing the Mental Rotation
Task (MRT) in Stage 1 and Stage 2 EOPD Using Brain Imaging
Presented by: Joyeta Razzaque, MD
Major Depression and Generalized Anxiety Disorder in Persons with Epilepsy: Correlations
with Commonly used Anti-seizure Medications
Presented by: Sidra Saleem, MD
Seizure Triggers in Persons with Epilepsy (PWE): Numbers from a Tertiary Care Neurology
Database
Presented by: Fahham Asghar, MD
Angiography Utilization in LVO Drip-and-Ship Patients: Comparing Air and Ground
Presented by: Rahul Rao, MD
Mental Rotation Task as a Clinical Tool: Comparison Across Age Groups
Presented by: Joyeta Razzaque, MD
Initiation of Antiepileptic Drugs in Acute Care Setting: Necessity to Avoid Overuse
Presented by: Sarah Haseen, DO
The Impact of Social Determinants of Health on Stroke Readmissions and Recovery
Presented by: Rahul Rao, MD
Medication Adherence in Persons with Epilepsy: Common Reasons for Missing Doses
Presented by: Hira Pervez, MD
Locked-in Syndrome Secondary to Vertebro-Basilar Dolichoectasia - and Unfortunate
Complication of a Rare Pathology in a Young Patient
Presented by: Syed Owais, MD
Optic Nerve Diffusion Restriction - A Non-Invasive Technique for Idiopathic Intracranial
Hypertension
Presented by: Hira Pervez, MD
Development of a Chronic Paraquat and Lectin-induced Rat Model Recapitulating the
Human Pathogenesis of Parkinson's Disease
Presented by: Vaibhavi Peshattiwar, PhD
Sex Differences in Brain Activation for MRT Using fMRI in Adults
Presented by: Joyeta Razzaque, MD
2024 Virtual Posters
Fulminant Demyelination with Delayed Diagnosis and Treatment - A Rare Case of Marburg
MS-variant Presenting as Stroke Mimic
Hira Pervez, MD, Ahsan Ali, MD, Sumayya Naz, MD, Dionne Elizabeth Swor, DO, Boyd Koffman,
MD, Deepa Malaiyandi, MD
Attention Defficit Hyperactivity Disorder and Seizure Type
Imran, Ali, MD, Fahham Asghar, MD, Sidra Saleem, MD, Alisa Gega, Ajaz Sheikh, MD
People with Epilepsy (PWE) and Attention Deficit hyperactivity Disorder (ADHD)/ Attention
Deficit Disorder (ADD)
Syed Muhammad Owais, MD, Fahham Asghar, MD, Hira Pervez, MD, Sidra Saleem, MD, Sumayya
Naz, MD, Ajaz Sheikh, MD, Naeem Mahfooz, MD, Joyeta Razzaque, MD, Rabia Zubair, MD,
Bashar Saour, MD, Anum Riaz, MD, Imran Ali, MD
Atypical Electroencephalographic Findings in Patients with Sub-acute Encephalopathy
with Seizures in Alcoholics (SESA) Syndrome
Hira Pervez, MD, Sumayya Naz, MD, Syed Muhammad Owais, MD, Adam Mierzwa, MD, Ajaz
Sheikh, MD
Effect of Resistance Training on Parkinson's Disease Motor Symptoms
Noor Abdulhameed, BS, Ethan Kosco, BS, Benjamin Klein BS
Striking Multi-focal Diffusion Restriction with Intracranial Hypertension - Is it
CHANTER Syndrome?
Syed Muhammad Owais, MD, Joyeta Razzaque, MD, Hira Pervez MD, Vinh Pham, MD, Sahil
Sakibuzzaman, MD, Mohammad Samara, MD, Vicki A. Ramsey-Williams, MD, PhD, Bashar Saour,
MD, Elysia James, MD
Auras in Persons with Focal and Generalized Epilepsy: Types and Patient Numbers from
a Tertiary Level Epilepsy Center
Fahham Asghar, MD, Sumayya Naz, MD, Vicki A. Ramsey-Williams, MD, PhD, Ajaz Sheikh,
MD, Sidra Saleem, MD, Hira Pervez, MD, Imran Ali, MD, Anum Riaz, MD
My Brainstem is Dead: But am I?
Rayan Magsi, MD, Nina Atanasova, PhD
Atypical Clinical Signs and Electroencephalographic Correlates in Patients with Sub-acute
Encephalopathy with Seizures and Alcoholics
Hira Pervez, MD, Adam Mierzwa, MD, Syed Muhammad Owais, MD, Mohamad Samara, MD, Vinh
Pham, MD, Ajaz Sheikh, MD
Single Center Experience Using the 3-max Catheter in Medium and Distal Vessel Occlusion
Aizaz Ali, MD, Rahul Rao, MD, Brandon Sharkey, Alisa Gega, Marion Oliver, MD, Syed
F. Zaidi, MD
Electroencephalographic Findings with Status Epilepticus in Chronic Alcoholism - A
Rare Case of SESA Syndrome
Syed Muhammad Owais, MD, Hira Pervez, MD, Joyeta Razzaque, MD, Fahham Asghar, MD,
Sumayya Naz, MD, Ajaz Sheikh, MD, Tayyaba Tariq, MD, Naeem Mahfooz, MD, Radha Patel,
MD, Sahil Kapur, Imran Ali, MD
Seizure Triggers in Persons with Epilepsy (PWE): A Cohort of 1975 Patients
Fahham Asghar, MD, Meghana Ranabothu, Sumayya Naz, MD, Hira Pervez, MD, Sidra Saleem,
MD, Ajaz Sheikh, MD, Anum Riaz, MD, Imran Ali, MD, Vicki A. Ramsey-Williams, MD, PhD
Achromobacter Xylosidans - Positive Meningitis Secondary to Exposed Intrathecal Catheter
Ajay Nair, BA, Vito Lucarelli, Alastair Hoyt, MD
2024 Poster and Platform presentation Judges
We would like to express our sincere appreciation to our poster and platform presentation judges for their valuable time, expertise, and support in evaluating the submissions and helping to ensure the success of our event.
Vicki Ramsey-Williams, MD, PhD
Associate Professor, Director Neurology Clerkship
University of Toledo
Mouhammad Jumaa, MD, FSVIN, FAHA
Professor of Neurology, Vascular and Interventional Neurology, Program Director, Vascular
Neurology Fellowship, Medical Director, ProMedica Stroke Network
University of Toledo
Jason Schroeder, MD
Professor and Interim Chair, Department of Surgery Chief, Division of Neurosurgery
University of Toledo
Dionne Swor, DO
Assistant Professor
University of Toledo
Jack Parent, MD
William J Herdman Professor of Neurology, Research Professor, Michigan Neuroscience
Institute, Staff Physician, Ann Arbor VA Healthcare Center, Co-director, Epilepsy
Program, Director, Human Stem Cell and Gene Editing Core
The University of Michigan