Department of Neurology

Dr. Venkiteswaran, MSc, Ph.D.

Associate Professor

Special Interests

Parkinson's Disease Research
CN Immunology


BSc, University of Calicut, Calicut, India 
MSc, Cochin University of Science and Technology, Cochin, India
PhD, University of Calicut, India 

Professional Appointments

Associate Professor, University of Toledo, Department of Neurology, 2021-present

Society Memberships

Parkinson's Study Group (PSG)
International Parkinson and Movement Disorder Society (MDS)
Society of Neuroscience (SfN)
American Society for Neural Therapy and Repair (ASNTR)


Manuscript Reviewer
Evidence Based Complimentary and Alternate Medicine
Cell Transplantation
Journal of Neuroscience Research
Neuroscience Journal
Parkinson's Disease

Editorial Board Member
Journal of Neurology and Neurobiology (ISSN 2379-7150)
Current Advances in Neurology and Neurological Disorders (ISSN 2637-6997)

Selected Publications


Parkinson Study Group, STEADY-PD III Investigators (Includes Venkiteswaran, K.).
Isradipine Versus Placebo in Early Parkinson Disease: A Randomized Trial. Online
ahead of print, 2020 Mar 31. Ann Intern Med. 2020;10.7326/M19-2534. NCT02168842. doi:10.7326/M19-2534. PMID: 32227247

Vishakh Iyer, Quynh Vo, Anthony Mell, Siven Chinniah, Ashley Zenerovitz, Kala
Venkiteswaran, Allen R. Kunselman, Jidong Fang and Thyagarajan Subramanian. Acute
levodopa dosing around-the-clock ameliorates REM sleep without atonia in
hemiparkinsonian rats. npj Parkinsons Dis. 2019; 5: 27. Published online 2019

Anselmi L, Bove C, Coleman FH, Le K, Subramanian MP, Venkiteswaran K,
Subramanian T, Travagli RA. Ingestion of subthreshold doses of environmental toxins
induces ascending Parkinsonism in the rat. npj Parkinson's Disease. 2018;4(1):30. doi:
10.1038/s41531-018-0066-0. PMID: 30302391. PMCID: PMC6160447

Venkiteswaran K, Subramanian T, Sue-Grigson P (2016) Commentary on - Human
Embryonic Retinal Pigment Epithelial (RPE) Cell Transplants for Chronic Refractory
Cocaine Addiction. Health Care: Current Reviews 4: 165. doi: 10.4172/2375-

Venkiteswaran K, Alexander DN, Puhl MD, Rao A, Piquet AL, Nyland
JE, Subramanian MP, Iyer P, Boisvert MM, Handly E, Subramanian T, Grigson PS.
Transplantation of Human Retinal Pigment Epithelial Cells in the Nucleus Accumbens of
cocaine self-administering rats provides protection from reinstatement. Brain Res Bull.
2016; 123: 53-60 PMID: 26562520.

Subramanian, T., Venkiteswaran, K., Update on Movement Disorders – five new things
in Parkinson’s disease. BMH Medical Journal 2015; 2(3):60-70

Wang, J., Yang, Q.X., Sun, X., Vesek, J., Mosher, Z., Vasavada, M., Chu, J., Kanekar, S.,
Shivkumar, V., Venkiteswaran, K., Subramanian, T., MRI Evaluation of Asymmetry of
Nigrostriatal Damage in the Early Stage of Early-onset Parkinson’s Disease, Parkinsonism
and Related Disorders, 2015; 21(6):590-6, PMID: 25825242

Quynh Vo, Timothy P. Gilmour, Kala Venkiteswaran, Jidong Fang, and Thyagarajan
Subramanian, Polysomnographic Features of Sleep Disturbances and REM Sleep
Behavior Disorder in the Unilateral 6-OHDA Lesioned Hemiparkinsonian Rat, Parkinson’s
Disease, vol. 2014, Article ID 852965, 2014.

Lieu, C.A., Venkiteswaran, K., Gilmour, T., Rao, A., Petticoffer, A., Gilbert, E.V.,
Deogaonkar, M., Manyam, B.V. and Subramanian, T. The anti-parkinsonian and antidyskinetic
mechanisms of Mucuna pruriens in the MPTP-treated non-human primate.
Evidence-Based Complementary and Alternative Medicine, 2012; 2012: 840247. PMID
22997535. PMC3445014.

Piquet, AL.*, Venkiteswaran, K.*, Marupudi, NI, Berk, M., Subramanian, T.
Immunological challenges to cell transplantation in Parkinson’s disease. Brain Res Bull.,
88(4): p.320-331 2012 PMID: 22521427. PMC3376210. Equal first authors.

Gilmour, TP., Piallat, B., Lieu, CA., Venkiteswaran, K., Ramachandra, R., Rao, AN.,
Petticoffer, AC., Berk, M., Subramanian, T., The effect of striatal dopaminergic grafts on
the neuronal activity in the substantia nigra reticulata and subthalamic nucleus in
hemiparkinsonian rats, Brain, 134(Pt 11):3276-89. PMID: 21911417. PMCID:

Lieu CA, Kunselman AR, Manyam BV, Venkiteswaran K, Subramanian T. A water extract
of Mucuna pruriens provides long-term amelioration of Parkinsonism with reduced risk for
dyskinesias. Parkinsonism Relat Disord. 2010 Aug; 16 (7) :458-65. PMID:20570206.

Zhao, Z., Krishnaney, A., Teng, Q., Garrity-Moses, M., Tanase, D., Liu, JK.,
Venkiteswaran, K., Subramanian, T., Davis, M., Boulis, NM., Anatomically discrete
functional effects of adenoviral clostridial light chain gene-based synaptic inhibition in the
deep layers of the superior colliculus/deep mesencephalic nucleus of the midbrain, Gene
Therapy 13 (12): 942-952, 2006. PMID: 16511525

Venkiteswaran, K. Xiao K., Summers S., Calkins C. C., Vincent P. A., Pumiglia K., and
Kowalczyk A. P. Regulation of endothelial barrier function and growth by VE-cadherin,
plakoglobin, and {beta}-catenin, Am J Physiol Cell Physiol Sept. 2002 283: C811-C821.
PMID: 12176738.

Venkiteswaran K, Sgoutas DS, Santanam N, Neylan JF. Tacrolimus, cyclosporine and
plasma lipoproteins in renal transplant recipients. Transplant International. 2001 Dec;
14(6): 405-10. PMID: 11793038.

Nagarajan S, Venkiteswaran K, Anderson M, Sayed U, Zhu C, Selvaraj P. Cell-specific,
activation-dependent regulation of neutrophil CD32A ligand-binding function. Blood. 2000
Feb 1; 95(3): 1069-77. PMID: 10648424.

Bruce Sundstrom, Kala Venkiteswaran, Periasamy Selvaraj and Demetrious Sgoutas
Oxidized lipoproteins enhance the in vitro tube formation by endothelial cells cultured on
Matrigel. Angiogenesis: Models, Modulators and Applications, Edited by Maragoudakis,
Plenum Press, New York, 367-375, 1998.

McHugh, R. S., Venkiteswaran, K., Wang Y-C. and Selvaraj P. Cells modified with lipidanchored
proteins: A novel approach to cancer vaccines. Proceedings of the Symposium
on: Frontiers in Biology and Biotechnology, Ed. A. Oommen, pp. 26-27, 1997.

Shanavas KR, Venkiteswaran K, Vasudevan DM, Vijayakumar T, Yadav M. Anti-HHV-6
antibodies in normal population and in cancer patients in India. J Exp Pathol. 1992; 6(1-
2): 95-105. PMID: 1320669.

Vasudevan D. M., Shanavas K. R., Venkiteswaran K, Vijayakumar T., Kumari T. V.,
Association of Herpes group of viruses with oral cancers, Proceedings of the 2nd
International Congress on oral cancers, New Delhi, India.1991

Book Chapters

Kala Venkiteswaran, Vikram Shivkumar and Thyagarajan Subramanian. Early Parkinson’s
disease – Essentials of Diagnosis and Management. Pearls in Neurology, 2019.

Elizabeth Lucassen, Kala Venkiteswaran, Thyagarajan Subramanian “Secondary
Parkinsonism” in Imaging of Neurodegenerative Disorders, Ed. Sangam Kanekar, Thieme
Publishers, 2014.

Lieu, C.A., V. Shivkumar, T.P. Gilmour, K. Venkiteswaran, M.J. Nolt, M. Deogaonkar, and T.
Subramanian, Pathophysiology of Drug-Induced Dyskinesias, in Symptoms of Parkinson's
Disease, A.Q. Rana, Editor. 2011, InTech Open Access Publisher: Rijeka. p. 83-114.

Research Interests

Gut-brain axis during early stages of Parkinson's disease



Last Updated: 1/29/24