The University of Toledo

Advanced Microscopy & Imaging Center Overview

The University of Toledo Advanced Microscopy & Imaging Center on the Health Science Campus is a 3,000 square foot facility designed to bring together advanced light and fluorescence microscopy systems and “state of the art” image analysis software to perform biomedical research.  Current projects in this center include work in Cancer, Genetics, Neurobiology, Vascular Biology, Pathology, Pulmonology, and Arthritis research.  The Center consists of a 1,000 square foot General Microscopy Laboratory with 12 separate “work stations” housing individual, computer-based microscopy systems.  The center also includes an 800 square foot, Tissue-culture Microscopy Laboratory with 6 separate “work stations” for microscopy systems dedicated to the study of living cells, along with complete culture facilities and a cryogenic storage system. 

The mission of the Advanced Microscopy & Imaging Center is to provide facilities, instruments and training for scientists, students and clinicians engaged in translational research within UT and sister institutions.  Indeed, investigators from the UT Main Campus, Bowling Green State University, Case Western Reserve University, The University of Michigan and Wright State University have already expressed an interest in using this facility.  The Advanced Microscopy & Imaging center will also be focused on developing new technologies for automating and providing advanced imaging technologies.  The current systems running in the facility include:   

• Confocal Microscopy with 3-D Construction
• Fluorescence Microscopy
• Time Lapse Imaging with Fluorescence
• Multi-photon Microscopy in Real-Time
• TIRF Microscopy
• Laser Capture Microscopy
• Transmission Electron Microscopy
• Basic Light Microscopy
• Absorption Cytometric Measurement of Cancer Cell DNA Content
• Image Analysis of Vascular Injury
• Fluorescence in situ Hybridization of Cancerous and Normal Chromosomes