Evidence-Based Medicine is the integration of best research evidence with clinical expertise and patient values. (Sackett DL, Straus SE, Richardson WS, et al. Evidence-based medicine: how to practice and teach EBM. 2nd ed. Edinburgh: Churchill Livingstone, 2000.)
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TRIP (Turning Research Into Practice) Database Plus
Simultaneously searches evidence-based sources of systematic reviews, practice guidelines, and critically-appraised topics and articles -- including most of those listed above and many more. Also searches MEDLINE's Clinical Queries, medical image databases, e-textbooks, and patient information leaflets.
Systematic Reviews / Meta-Analyses
The "best single source of reliable evidence about the effects of health care." Updated regularly and includes these databases:
- Cochrane Database of Systematic Reviews
- Database of Abstracts of Reviews of Effectiveness (DARE)
- Cochrane Controlled Trials Register
- Cochrane Methodology Register
- NHS Economic Evaluation Database
- Health Technology Assessment Database
- Cochrane Database of Methodology Reviews (CDMR)
A quick help guide is available.
The Database of Abstracts of Reviews of Effect (DARE)
Full-text database containing structured abstracts of systematic reviews from a variety of medical journals. DARE is produced by the National Health Services' Centre for Reviews and Dissemination (NHS CRD) at the University of York. DARE records cover topics such as diagnosis, prevention, rehabilitation, screening, and treatment.
Systematic Reviews are also searchable in MEDLINE:
- EBSCOhost MEDLINE: Enter your search query. Click on the "Limits" icon; select "Systematic Reviews" under "Subject Subsets."
This resource is restricted to faculty, residents, staff, and students who are registered with the Mulford Library (Off-campus users click here)
- PubMed: Click on "Clinical Queries" on the left side of the screen; select "Find Systematic Reviews" and enter your search query, OR click on "Search Options" and select from the "Systematic Reviews" dropdown menu after doing the search.
Go to the Mulford Library Homepage and click on PubMed@UT in the Mulford Quick Links menu to access these resources.
The public version of PubMed can be accessed through pubmed.gov.
The Agency for Health Care Research and Quality (US Department of Health and Human Services) coordinates, supports, and reports on all Federal quality improvement efforts and health services research. Links to freely available evidence reports and technology assessments on topics relevant to clinical, social science/behavioral, economic, and other health care organization and delivery issues.
OT Seeker (Occupational Therapy Systematic Evaluation of Evidence)
OTSeeker is a database that contains abstracts of systematic reviews and randomised controlled trials relevant to occupational therapy. Trials have been critically appraised and rated to assist one in evaluating their validity and interpretability. Published by a team of occupational therapists from two Australian universities.
Core Library for Evidence-Based Practice
Includes many links to EBM articles on basic statistics for clinicians, systematic reviews, meta-analysis, how to read a paper, understanding controlled trials, and getting research into practice.
Critically-Appraised Topics
Summarizes the current state of knowledge about the prevention and treatment of clinical conditions, based on thorough searches and appraisal of the literature. It describes the best available evidence from systematic reviews, RCTs, and observational studies where appropriate, and if there is no good evidence it says so.
National Guideline Clearinghouse
A comprehensive database of evidence-based clinical practice guidelines and related documents produced by the Agency for Health Care Research and Quality, in partnership with the American Medical Association and the American Association of Health Plans. Updated weekly.
Note: Guideline evidence varies from expert opinion to high levels of evidence.
Produced by The American College of Physicians, The Physicians' Information and Education Resource (PIER) is a tool for finding authoritative, evidence-based information for the diagnosis and treatment of disease. It contains information on prescription and over-the-counter drugs, screening and prevention, ethical and legal issues, and more.
There is a PDA version of this product.
Critically-Appraised Individual Articles
The editors of this journal screen the top 100+ clinical journals and identify studies that are methodologically sound and clinically relevant. An enhanced abstract, with conclusions clearly stated, and a commentary are provided for each selected article. Published by the American College of Physicians-American Society of Internal Medicine.
Check ACP journal club (Online) in the UT catalog for multiple subscriptions.
Bandolier (maintained by the Pain Research Unit at the University of Oxford) distills evidence-based medicine techniques from PubMed and Cochrane to provide advice about particular treatments for healthcare professionals and consumers. This freely available content may be accessed through the Knowledge Library, the monthly journal, extended essays, and the Oxford Pain Internet Site.
Quality articles from over 110 clinical journals are selected by research staff, and then rated for clinical relevance and interest by an international group of physicians. Includes a searchable database of the best evidence from the medical literature and an email alerting system. From BMJ Publishing Group and McMaster University's Health Information Research Unit.
Published for the National Health Service in England primarily as a succinct "point of care" resource for primary caregivers. Core material on nearly 500 clinical scenarios includes differential diagnosis, admission and referral guidelines, management for patients and (often British based) prescription drugs. Cochrane Review highlights, one sentence summaries and links.
Health Services Technology Assessment Text (HSTAT)
The US National Library of Medicine sponsors this free resource that provides health information and supports health care decision making. Full text documents include Evidence Reports, Clinical Practice Guidelines, Technical Reviews and Summaries, and a Guide to Clinical Preventative Services.
User's Guides to Evidence-Based Practice (Center for Health Evidence)
The Centre for Health Evidence in Edmonton maintains a full set of the prepublication versions of the articles in JAMA's Users' Guides to the Medical Literature series. Mulford also has access to the 2002 Users' Guides Interactive through our JAMA subscription.
PubMed is the free version of MEDLINE made available by National Center for Biotechnology Information (NCBI) at the National Library of Medicine (NLM). Searchers on the University of Toledo Health Science Campus or those who are registered with the Mulford Library should search PubMed@UT; it tells PubMed to show information about locally-available online journals.
To include locally-available online journals for the PubMed search via the Entrez cross-database search page use this URL: URL: http://www.ncbi.nlm.nih.gov/gquery/gquery.fcgi?-holding=ohiolinklib,mcolib_fft,f1000&otool=ohiolink.To limit your PubMed search to the best evidence-producing studies: Click on "clinical queries" (on the left side of the screen). This specialized search is intended for clinicians and has built-in search "filters." Four study categories--therapy, diagnosis, etiology, prognosis--are provided, and you may indicate whether you wish your search to be more sensitive (i.e., include most relevant articles but probably including some less relevant ones) or more specific (i.e., including mostly relevant articles but probably omit a few).
EBSCOhost Medline
1966-present [off-campus access]
EBSCOhost MEDLINE also provides links to the full-text articles that are available at the Mulford Library.To limit your EBSCOhost MEDLINE search to the best evidence-producing studies: Clinical Queries (See PubMed) is searchable in EBSCOhost; Limit your results with options from the "Clinical Queries" dropdown menu on the initial search page, OR click on "Search Options" and select from the "Clinical Queries" dropdown menu after doing the search.
International coverage of the professional and academic literature in psychology, medicine, psychiatry, nursing, sociology, education, pharmacology, physiology, linguistics, and other areas.
To limit your PsycINFO search to the best evidence-producing studies: Click on the "Limits" icon to use "Clinical Queries" or limit to "methodology" types.
CINAHL, 1982-present [off-campus access]
CINAHL (the main database for nursing and allied health literature) indexes articles from the professional journal literature from 1982 to the present (though some journal titles are retrospectively indexed back to 1937). Articles from more than 1000 journals are covered, as well as books, pamphlets, dissertations, books and chapters, audiovisuals, research instruments, evidence-based care sheets, software, and more.To limit your CINAHL search to the best evidence-producing studies: Click on the "Limits" icon to use "Clinical Queries" or limit to "Research" or other "publication" types (i.e., systematic review).
Mulford Library help sheets/tutorials ~ CINAHL tutorials (from the U Florida HSC Libraries)
Note: Evidence in these resources may vary from expert opinion to high levels of evidence.
A clinical information resource, which offers up-to-date, fully referenced expert answers to patient-care, diagnosis, and treatment questions. Topic reviews are written by recognized authorities who review the topic, synthesize the evidence, summarize key findings, and provide specific recommendations.
(Access restrictions: UpToDate is licensed for on-site use only at The University of Toledo, Main and Health Science Campuses. Remote access is not permitted).
Physician authors and editors contribute to the eMedicine Clinical Knowledge Base, which contains articles on 7,000 diseases and disorders. The evidence-based content provides the latest practice guidelines in 62 medical specialties. eMedicine's professional content undergoes multiple levels of physician peer review.
Searchable and continually updated version of Harrison's Principles of Internal Medicine. Available at UT through AccessMedicine.
Electronic textbook of general medicine; updated continually.
Centre for Evidence-Based Medicine (Oxford University)
The Centre promotes evidence-based health care and provide support and resources to anyone who wants to make use of them. Includes the EBM Toolbox, an assortment of materials which are very useful for practitioners of EBM, and EBM Teaching Materials, including PowerPoint presentations.
Centre for Evidence-Based Medicine (Toronto)
Includes many resources for practicing and teaching EBM.
A selective list of additional EBM websites developed and maintained by Duke University Medical Center Library.
From the School of Health and Related Research (ScHARR) at the University of Sheffield, UK. Includes a comprehensive list of EBM databases, journals, articles, and other information sources.
Users' Guides to Evidence-Based Practice
From the University of Alberta's Centre for Health Evidence. Includes the complete set of EBM Users' Guides originally published as a series in the Journal of the American Medical Association (JAMA).
Evidence-Based Medicine Toolkit
A collection of tools for identifying, assessing and applying relevant evidence for better health care decision-making based on the work of the Evidence Based Medicine Working Group. The site contains in-depth search strategies for finding EBM articles and guides to using them.
Evidence-Based Health Care Resources on the Internet
Compiled by the Medical Library Association, this site includes many links to EBM resources. Includes EBM tutorial sites, organizations and journals, search filters, journals, practice guidelines, and systematic reviews.
Evidence-Based Practice and Guidelines
The University of Washington maintains this list of links to EBM resources. The site has links to finding tools, definitions, glossaries, calculators, and evidence-based medicine research.
Introduction to Evidence-Based Medicine
From Duke University Medical Center Library and University of North Carolina at Chapel Hill Health Sciences Library.
Evidence-Based Medicine Resources for the PDA
A list of resources from the Dartmouth Biomedical Libraries.
Currently no content.
EBM Pyramid and EBM Page Generator,
copyright 2006 Trustees of Dartmouth College and Yale University.
All Rights Reserved.
Produced by Jan Glover, David Izzo, Karen Odato and Lei Wang.
