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Seminar Series: 2012-2013

Department of Physiology and Pharmacology & CVMD Graduate Program

Director, Ashok Kumar, Ph.D., FAHA

Seminars: 2012-2013	Speaker	Title
Wednesday December 5, 2012 11:15 am - 12:15 pm Room 105 Health Education Bldg.	Curt D. Sigmund, Ph.D. Professor and Head, Department of Pharmacology Roy J. Carver Chair in Hypertension Research Roy J. and Lucille A. Carver College of Medicine The University of Iowa	"Novel Role of the Cullin-3 Pathway in Hypertension"
Wednesday October 3, 2012 11:15 am - 12:15 pm Room 105 HEB	Andrea Kalinoski, Ph.D. Assistant Professor, Technical Director Advanced Microscopy & Imaging Center The University of Toledo, HSC Dept of Surgery College of Medicine	"Vascular reactivity: Physiology & Genetics"
Center for Diabetes and Endocrine Research (CeDER) Thursday September 20, 2012 4:00-5:00 pm Room 375 BHS	E. Dale Abel, M.D., Ph.D. The University of Utah, School of Medicine Professor of Medicine & Biochemistry & Human Genetics Chief: Div of Endocrinology Metabolism & Diabetes Senior Investigator: Program in Molecular Medicine Josie l Johnson Professorship in Molecular Biology	"Cardiac adaptations of insulin resistance"
Seminars: 2011-2012	Speaker	Title
Wednesday June 27, 2012 11:15 am - 12:15 pm Room 375 BHS	David Allison, M.D., Ph.D. Professor The University of Toledo Dept of Surgery, Dir of Surgical Research College of Medicine	"Genetic instability and housekeeping gene expression"
Wednesday June 20, 2012 11:15 am - 12:15 pm Room 105 HEB	Ashok Kumar, Ph.D. FAHA Professor The University of Toledo, HSC Dept of Physiology & Pharmacology College of Medicine Toledo, OH	"Humanized transgenic mice to understand genetics of hypertension"
*MEDICINE GRAND ROUNDS &* DEPT OF PHYSIOLOGY PHARMACOLOGY Keynote Speaker Wednesday June 13, 2012 12:15 pm Room 103 HEB	Jeffrey M. Friedman, M.D., Ph.D. Marilyn M. Simpson Professor The Rockefeller University New York, NY	"Discovery of Leptin gene and the biologic basis of obesity"
Wednesday June 6, 2012 11:15 am - 12:15 pm Room 105 HEB	Guillermo Vazquez, Ph.D. Assistant Professor The University of Toledo, HSC Dept of Physiology & Pharmacology College of Medicine Toledo, OH	"Unraveling the roles of TRPC channels in atherosclerosis"
Wednesday May 30, 2012 11:15 am - 12:15 pm Room 105 HEB	Jennifer Hill, Ph.D. Assistant Professor The University of Toledo, HSC Dept of Dept of Physiology & Pharmacology College of Medicine Toledo, OH	"Of mice and women: The impact of metabolic status on fertility"
Wednesday May 9, 2012 11:15 am - 12:15 pm Room 105 HEB	Beata Lecka-Czernik, Ph.D. Professor The University of Toledo, HSC Dept of Orthopedics, Dept of Physiology & Pharmacology College of Medicine Toledo, OH	"PPARgamma nuclear receptor integrates bone with energy metabolism system"
Center for Diabetes and Endocrine Research (CeDER) Seminar: Friday April 20, 2012 4:00 pm - 5:00 pm Room 375, BHS	John J. Bellizzi, III, Ph.D. Assistant Professor Department of Chemistry, Main Campus The University of Toledo Toledo, OH	"Biochemical and structural studies of circadian oscillator proteins: post-translational modifications and metabolic sensors"
Wednesday March 28, 2012 11:15 am - 12:15 pm	Kamal Rahmouni, Ph.D. Associate Professor, Department of Pharmacology, Department of Internal Medicine Roy J. and Lucille A. Carver College of Medicine The University of Iowa, Iowa City, IA	"Obesity-Associated Hypertension: Mechanistic Insights"
Co-Sponsored: Biomedical Sciences Program Cancer Biology & Center for Diabetes and Endocrine Research (CeDER) Thursday March 22, 2012 4:00 pm	Richard DiMarchi, Ph.D. Standiford H. Cox Professor of Chemistry Linda & Jack Gill Chair in Biomolecular Sciences Indiana University, Department of Chemistry Bloomington, IN	"Novel Glucagon peptides that demonstrate the virtues of combinatorial pharmacology in the treatment of obesity and diabetes"
Wednesday March 21, 2012 11:15 am - 12:15 pm	Saverio Luzzi, M.D. Professor The University of Siena, Italy	"Pathophysiology of primary headache"
Wednesday March 14, 2012 11:15 am - 12:15 pm	Christopher Cooper, M.D. Professor Chief, Division of Cardiovascular Medicine Director of Cardiovascular Research Center Department of Medicine, The University of Toledo Toledo, OH	"Ischemic renal disease: reconsidering our understanding of the relationship between the stenosis and the kidney"
Wednesday March 7, 2012 11:15 am - 12:15 pm	Stavroula Kousteni, Ph.D. Associate Professor Department of Medicine and Physiology College of Physicians and Surgeons Columbia University New York, NY	"Update on the Cross-Talk between bone and energy metabolism"
Wednesday February 29, 2012 11:15 am - 12:15 pm	Bina Joe, Ph.D. Professor Department of Physiology & Pharmacology College of Medicine The University of Toledo Toledo, OH	"Under pressure to find genes controlling blood pressure"
Wednesday February 15, 2012 11:15 am - 12:15 pm	Zi-Jian Xie, Ph.D. Professor Department of Physiology & Pharmacology College of Medicine The University of Toledo Toledo, OH	"Na/K-ATPase in signal transduction"
Wednesday November 30, 2011 11:00 am - 12:00 pm	Mario Petrini, M.D. Dean of the School of Medicine and Chief of Oncology and Transplant The University of Pisa Pisa, Italy	"Clinical application of stem cells?"
Wednesday September 7, 2011 11:00 am - 12:00 pm	Anumpam Agarwal, M.D. Interim Chairman, Department of Medicine Director, Division of Nephrology The University of Alabama at Birmingham Birmingham, AL	"Adaptive responses in renal and vascular injury: Role of Heme oxygenese-1"
Seminars: 2010-2011	Speaker	Title
Wednesday May 18, 2011 11:00 am - 12:00 pm	Sang Don Lee, Ph.D. Professor, Pusan National University Yangsan Hospital, School of Medicine Department of Urology, Division of Pediatric Urology, Busan, Korea	"Understanding the basic function, morphological and molecular changes of bladder after bladder outlet obstructions."
Wednesday April 28, 2011 11:00 am - 12:00 pm	1998 NOBEL LAUREATE Ferid Murad, M.D., Ph.D. The University of Texas at Houston	"Discovery of nitric oxide and cyclic GMP in cell signaling and the role in drug development"
Wednesday April 14, 2011 11:00 am - 12:00 pm	Raymond A. Frizzell, Ph.D. Professor, Director of Cystic Fibrosis Research Center, Department of Cell Biology The University of Pittsburgh Pittsburgh, PA	"Two modes of ion channel regulation by 14-3-3 proteins"
Wednesday April 13, 2011 11:00 am - 12:00 pm	Matteo A. Russo, Ph.D. Professor, Experimental Medicine The University of Rome, Italy	"Sirtuins and physical exercise in the maintenance and repair of post-mitotic cells"
Wednesday April 6, 2011 10:30 am - 2:00 pm	STEM CELL: Basic Science & Clinical Application Symposium: Speakers: Dr. Donald Phinney Dr. Eva Mezey Dr. Nader G. Abraham Dr. Daniel J. Weiss Dr. Luis A. Ortiz	Titles of talks: -Functional Heterogeneity of MSC Populations and Implications for clinical medicine. -Immuno-modulation by bone arrow derived stromal cells. -Introduction of stem cells plasticity and types. -Clinical trials with MSCs. -The MSC secretome in acute lung injury"
Wednesday March 9, 2011 11:00 am - 12:00 pm	Richard J. Roman, Ph.D. Professor & Chair, Department of Pharmacology & Toxicology, The University of Mississippi Medical Center	"Genetic basis of altered myogenic response and the development of renal disease in FHH rats"
Wednesday February 23, 2011 11:00 am - 12:00 pm	Michal Schwartzman, Ph.D. Professor & Chair of Pharmacology New York Medical College Valhalla, NY	"Cytochrome P450-derived eicosanoids in the regulation of renal function and blood pressure"
Wednesday February 16, 2011 11:00 am - 12:00 pm	David Stec, Ph.D. Associate Professor, Director, Transgenic Core The University of Mississippi Medical Center Jackson, MS	"Role of heme oxygenase-1 and its metabolites in the regulation of blood pressure"
Wednesday February 16, 2011 11:00 am - 12:00 pm	Jane Reckelhoff, Ph.D. Billy S. Guyton Distinguished Professor, Professor of Physiology & Biophysics, Director, Women's Health Research Center, The University of Mississippi Medical Center, Jackson, MS	"Update on sex differences in control of blood pressure"
Seminars: 2009-2010	Speaker	Title
Wednesday May 20, 2010 11:00 am - 12:00 pm	Stephen Peterson, M.D. Executive Vice Chair of the Department and Professor of Medicine Medical College of New York Valhalla, NY	"Pre-clinical and clinical applications of Apo lipoprotein A-1 mimetic peptide, L-4F in obesity and diabetes" Host: Dr. Abraham
Wednesday May 13, 2010 11:00 am - 12:00 pm	John E. Hall, Ph.D. Arthur C. Guyton Professor & Chair Associate Vice Chancellor for Research Department of Physiology & Biophysics University of Mississippi Medical Center Jackson, MS	"Pathophysiology of hypertension in obesity/metabolic syndrome" Host: Dr. Abraham
Wednesday May 5, 2010 11:00 am - 12:00 pm	Eduardo Nillni, Ph.D. Professor of Medicine Departments of Medicine, Molecular Biology, Cell Biology & Biochemistry Brown University Boston, MA	"Physiological response of the thyroid axis in diet-induced obesity hypothalamic endoplasmic reticulum stress alters POMC processing and contributes to Leptin resistance" Host: Dr. Sonia Najjar
Wednesday March 19, 2010 11:00 am - 12:00 pm	David Bernlohr, Ph.D. Distinguished McKnight University Professor and head of the Dept of Biochemistry, Molecular Biology and Biophysics, The University of Minnesota Minneapolis, MN	"Mitochondrial dysfunction and insulin resistance" Host: Dr. Sonia Najjar
Wednesday March 10, 2010 11:00 am - 12:00 pm	Curt D. Sigmund, Ph.D. Professor, Department of Medicine and Molecular Physiology & Biophysics, University of Iowa, Carver College of Medicine Iowa City, IA
Wednesday January 13, 2010 11:00 am - 12:00 pm	Helmy M. Siragy, M.D., FACP, FAHA Professor of Medicine and Endocrinology University of Virginia Charlottesville, Virginia	"Renin: Old enzyme with a new story"
Thursday December 10, 2009 11:00 am - 12:00 pm	Silvana Obici, M.D. Associate Professor Department of Internal Medicine-Endocrinology University of Cincinnati	"Role of CB1 Receptors in the Control of Energy Metabolism"
Tuesday November 24, 2009 11:00 am - 12:00 pm	Jian-Ping Jin, M.D., Ph.D. Professor and Chairman Department of Physiology Wayne State University Detroit, Michigan	"Regulation of troponin in cardiac function and adaptation"
Wednesday November 18, 2009 12:00 - 1:00 pm	Carol Moreno-Quinn, M.D., Ph.D. Assistant Professor Department of Physiology Medical College of Wisconsin Milwaukee, Wisconsin	“Genomic strategies for dissecting complex diseases”
Tuesday November 10, 2009 12:00 - 1:00 pm	Andrey Sorokin, Ph.D. Professor of Medicine Division of Nephrology Medical College of Wisconsin Milwaukee, Wisconsin	“Endothelin Signaling and Hypertension Induced Nephropathy”
Wednesday November 4, 2009 11:00 – Noon	Mingyu Liang, M.B., Ph.D. Associate Professor Department of Physiology Medical College of Wisconsin	"Cellular Metabolism and Hypertension: Expect the Unexpected"
Seminars: 2008-2009	Speaker	Title
Tuesday May 19, 2009 Reception, 5:00-5:30 pm Talk, 5:30-6:30 pm Room 103 Health Education Building	Dr. Steven L. Shafer Editor-in Chief, Anesthesia & Analgesia	“From Dose to TCI: 40 Years of Progress in Clinical Pharmacology”
Tuesday May 19, 2009 12:00 – 1:00 PM	Pedro Jose, M.D., Ph.D. Professor Director, Center for Molecular Physiology Research Children's National Medical Center Department of Pediatrics The George Washington University School of Medicine and Health Sciences	“You Are What You Eat and What Your Parents Gave You”
Wednesday April 29, 2009 12:00 - 1:00 PM	Jacob Sznajder, M.D. Professor Medicine and Cell & Molecular Biology Chief, Pulmonary & Critical Care Medicine Feinberg School of Medicine, Northwestern University Evanston, IL	"Hypothalamic Mitochondrial Density and Function in Metabolism Regulation"
Wednesday March 18, 2009 12:00 - 1:00 PM	Jeffrey Gimble, M.D., Ph.D. Professor Cell Stem Biology Pennington Biomedical Research Center Baton Rouge, LA	"Adipose Stem Cells in the 4th Dimension"
Wednesday March 11, 2009 12:00 - 1:00 PM	Sandor Gyorke, Ph.D. Associate Director, Davis Heart & Lung Research Institute Director, Multiphoton/Confocal Microscopy Core Facility Ohio State University Columbus, OH	"Sarcoplasmic Reticulum Calcium Release in Normal and Diseased Heart: A View from Inside the SR Lumen"
Wednesday February 11, 2009 12:00 - 1:00 PM	Sabrina Diano, Ph.D. Associate Professor, Obstetrics & Gynecology and Neurobiology Yale University New Haven, CT
Thursday December 4, 2008 4:00 - 5:00 PM	Sonia M. Najjar, Ph.D. Professor, Physiology and Pharmacology Director, Center for Diabetes and Endocrine Research University of Toledo, College of Medicine Toledo, OH	"At the Crossroad of Obesity, Fatty Liver Disease and Metabolic Syndrome"
Wednesday November 19, 2008 12:00 - 1:00 PM	Nader G. Abraham, Ph.D. Professor and Director of Gene Therapy Department of Pharmacology and Medicine New York Medical College Valhalla, NY	"Adiponectin-HO-1 Interactions On Stem Cell Function In CVD And Metabolic Syndrome"
Wednesday November 12, 2008 12:00 - 1:00 PM	Stephen P. Soltoff, Ph.D. Assistant Professor of Medicine Division of Signal Transduction Department of Medicine Beth Israel Deaconess Medical Center Boston , MA	"Modulation of ERK Signaling via Energy Consumption in Salivary Cells: Another Use of Ouabain"
Wednesday November 5, 2008 12:00 - 1:00 PM	Peter K. Lauf, M.D. Professor Department of Pathology Wright State University Dayton, OH	"The Role of Electroneutral Cotransporters In Cell Function and Volume Regulation"
Tuesday October 28, 2008 11:30 - 12:30 pm	Mohan K. Raizada, Ph.D. Distinguished Professor Department of Physiology and Functional Genomics University of Florida Gainesville, FL	"ACE2: A New Target For Cardiovascular Disease Therapeutics"
Tuesday October 21, 2008 12:00 - 1:00 pm	Suresh C. Tyagi, Ph.D. Professor & Vice Chair for Research Department of Physiology & Biophysics Stodghill Endowed Chair in Biomedical Sciences University of Louisville School of Medicine Louisville, KY	"Endothelial Myocyte Matrix in Cardiac Remodeling: H2S a Cardioprotector"
Monday October 13, 2008 12:00 - 1:00 pm	Li-Na Wei, Ph.D. Professor Department of Pharmacology University of Minnesota Medical School Minneapolis, MN	"Signaling pathways regulating the action of nuclear receptors and coregulators – A comprehensive proteomic endeavor"
October 1, 2008 12:00 – 1:00 pm	William Schilling, Ph.D. Professor Department of Physiology and Biophysics Case Western Reserve University School of Medicine Cleveland, OH	“TRPC Channels in the Kidney”
September 10, 2008 12:00 – 1:00 pm	David W. Busija, Ph.D. Professor Physiology and Pharmacology Wake Forest University School of Medicine Winston-Salem, NC	"Detrimental Effects On The Cerebral Vasculature Of Insulin Resistance: What You Don’t Know Will Hurt You!”
August 13, 2008 12:00 – 1:00 pm	Devendra Agrawal, Ph.D. Professor Biomedical Sciences, Internal Medicine, Medical Microbiology & Immunology Creighton University School of Medicine Omaha, NE	"Vein Graft Disease: Why Is The Internal Mammary Artery Almost Immune To Restenosis?”

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