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Radiation Biology

UT HSC Medical Physics Course MPHY6160/8160 (CRN: 27965/27971) 
Spring semester 2015

 Class meeting time:   Wednesday 9:30 AM - 12:00 PM (4 PM – 6:30 PM for CC/KR lectures)

 Class meeting place:

Ruppert Center, Suit K, 0005A (DCC 2nd floor conference room for CC/KR lectures)

 Textbook:

Radiobiology for the Radiologist, 7th edition
Eric J. Hall, Amato Giaccia; Lippincott, Williams & Wilkins Co, Philadelphia, PA 

 Instructors:  Diana Shvydka, E. Ishmael Parsai, Krishna Reddy, Changhu Chen

 Grades: Midterm - 50%, Final exam - 50%

 

Syllabus:

Date

Prof.

Topic(s)

Chapters

14 Jan

EIP

Physics & Chemistry of Radiation Absorption

1

21 Jan

DS

DNA Strand Breaks; Chromosome Aberrations; Cell Survival Curves

2, 3

28 Jan

DS

Radiosensitivity and Cell Age in the Mitotic Cycle; Fractionated Radiation and the Dose-Rate Effect

4, 5

4 Feb

EIP

Oxygen Effects; Re-oxygenation; Linear Energy Transfer; Relative Biological Effectiveness

6, 7

11 Feb

CC

Time, Dose and Fractionation in Clinical Radiotherapy; Newer & Less Common Radiation Modalities

23, 24, 25 

18 Feb

KR

Effects of Total Body Irradiation; Radiation Cataractogenesis; Radiation Carcinogenesis

8, 10, 13

25 Feb

DS

Dose-Response Relationships; Normal Tissue Responses

19, 20

4 Mar

DS

MIDTERM EXAMINATION

1-8, 10, 13, 19, 20, 23-25

Week of Mar 11th

 

SPRING BREAK

 

18 Mar

KR

Cancer Biology

18

25 Mar

DS

Model Tumor Systems; Tumor Kinetics

21,22

1 Apr

CC

Radioprotectors; Radiosensitizers;  Chemotherapy Agents

9, 26, 27

8 Apr

EIP

Heritable Effects of Radiation; Effects of Radiation on the Embryo and Fetus

11, 12

15 Apr

DS

Hyperthermia

28

22 Apr

DS

Predictive Assays

 

29 Apr

EIP

Diagnostic Imaging; Nuclear Medicine; Radiation Risk vs. Benefit; Radiation Protection

15, 16, 17

6 May

DS

FINAL EXAMINATION

9, 11, 12, 15-18, 21, 22, 26-28

Last Updated: 6/26/15