The University of Toledo

Research Index for College of Pharmacy and Pharmaceutical Sciences Faculty

Index Terms

• ADMET, SAR 
• Age-Related Disorders
• Alzheimer's Disease
• Anticancer Agents
• Antimalarial Agents
• Autoimmune Disease
• Bioorganic and Heterocyclic Chemistry
• Biopolymeric Nanoparticles
• Cancer Chemotherapy
• Cancer diagnosis, treatment and prevention agents
• Chemical Biology
• Chemical Toxicology
• Chronic Inflammation
• Cilia Biology
• Clinical Outcomes in Infectious Diseases
• Cytosolic Sulfatransferase
• Diabetes
• DNA Damage and Cancer
• Drug Clearance, Targeting, Design, Delivery
• Drug Metabolism, including prodrug and soft drug design
• Electro Catalysts/Electrochemical Sensors
• Enzymology and protein chemistry
• HIV/AIDS
• Immunology
• Infectious Disease
• Innate Immunity
• Ischemic Brain Injury and Stroke
• Kidney Disease
• Mass Spectrometry
• Molecular Wires
• Natural Products
• Neurodegenerative Disorders
• NMR
• Organic Synthesis
• Oxidative Damage to Nucleic Acids
• Oxidative Stress
• Pharmacodynamics
• Pharmacoeconomics
• Pharmacogenomics
• Pharmacokinetics
• Quantum Dots
• Rheology
• Zebra Fish

Click on each faculty member's name to view curriculum vitae.

ADMET, SAR

Paul W. Erhardt, PhD
Professor Medicinal & Biological Chemistry
Joint Professor Biochemistry & Cancer Biology
Director Center for Drug Design & Development
paul.erhardt@utoledo.edu

Funding:
ca. $750 K annually from multiple sources

Key Words: 
ADMET SAR
Cancer diagnosis, treatment and prevention agents
Drug metabolism including prodrug and soft drug design
Drug targeting
Natural products
Synthetic medicinal chemistry

Age-Related Disorders

Amanda Bryant-Friedrich, PhD
Associate Professor of Medicinal and Biological Chemistry
Joint Associate Professor Chemistry
amanda.bryant-friedrich@utoledo.edu

Funding:      
National Science Foundation

Key Words: 
Age-related disorders
Anticancer agents
Antimicrobial agents
Cancer etiology
Chemical toxicology
Chronic inflammation
Oxidative damage to nucleic acids
Photodynamic therapy
Synthesis of modified nucleic acids
Synthesis of organic dyes

Zahoor A. Shah, PhD
Assistant Professor
Zahoor.shah@utoledo.edu

Funding:
National Institutes of Health (NCCAM; K99/R00)

Key Words: 
Age-related disorders
Ischemic brain injury and Stroke
Oxidative stress
Natural Compounds 
Alzheimer's Disease



Alzheimer's Disease

Isaac T. Schiefer, PhD
Research Assistant Professor
Isaac.schiefer@utoledo.edu

Key Words:
Chemical Biology
Organic Synthesis
Alzheimer's Disease
Ischemic Brain Injury and Stroke

Anticancer Agents

Amanda Bryant-Friedrich, PhD
Associate Professor of Medicinal and Biological Chemistry
Joint Associate Professor Chemistry
amanda.bryant-friedrich@utoledo.edu

Funding:      
National Science Foundation

Key Words: 
Age-related disorders
Anticancer agents
Antimicrobial agents
Cancer etiology
Chemical toxicology
Chronic inflammation
Oxidative damage to nucleic acids
Photodynamic therapy
Synthesis of modified nucleic acids
Synthesis of organic dyes

Sai Hanuman Sagar Boddu, Ph.D.
Assistant Professor of Pharmaceutics
S.Boddu@UTNet.utoledo.edu

L. M. V. Tillekeratne
Associate Professor
liyanaaratchige.tillekeratne@utoledo.edu

Key Words: 
Anticancer agents
Electro catalysts/thiol detection
Natural Products
Quantum dots

  

Antimicrobial Agents

Amanda Bryant-Friedrich, PhD
Associate Professor of Medicinal and Biological Chemistry
Joint Associate Professor Chemistry
amanda.bryant-friedrich@utoledo.edu

Funding:      
National Science Foundation

Key Words: 
Age-related disorders
Anticancer agents
Antimicrobial agents
Cancer etiology
Chemical toxicology
Chronic inflammation
Oxidative damage to nucleic acids
Photodynamic therapy
Synthesis of modified nucleic acids
Synthesis of organic dyes                 

Diane Cappelletty, PharmD
Associate Professor
diane.cappelletty@utoledo.edu

Key Words: 
Antimicrobial stewardship
Bacterial resistance
Clinical outcomes in infectious diseases
Fungal infections
Pharmacodynamics

Rose Jung, PharmD, BCPS
Visiting Associate Professor of Pharmacy Practice
Rose.jung@utoledo.edu

Key Words: 
Antimicrobial Resistance
Opportunistic pathogens
Multi-drug resistance
Pseudomonas aeruginosa
Methicillin-resistant Staphylococcus aureus
Molecular mechanisms
Genetic predispositions
Molecular epidemiology of antimicrobial resistance

Autoimmune Diseases

Hermann von Grafenstein, PhD
Associate Professor
hermann.grafenstein@utoledo.edu

Funding:      
National Institutes of Health (NIAID; R15)

Key words: 
Autoimmune diseases
Inflammation
Ligand-receptor interactions
Mass spectrometry
NMR
Peptide-MHC complexes
Protein structure determination
Toll-like receptor associated proteins

 

Biopolymeric Nanoparticles

Sai Hanuman Sagar Boddu, Ph.D.
Assistant Professor of Pharmaceutics
S.Boddu@UTNet.utoledo.edu  

Jerry Nesamony, PhD
Assistant Professor of Pharmaceutics
jerry.nesamony@utoledo.edu

Key Words: 
Biopolymeric nanoparticles
Drug delivery
Dynamic light scattering
Liposomes
Microemulsions
Nanostructured liquid systems
Rheology
Sub-ambient thermal analysis

 

Cancer Chemotherapy  

Sai Hanuman Sagar Boddu, Ph.D.
Assistant Professor of Pharmaceutics
S.Boddu@UTNet.utoledo.edu

Cancer diagnosis, treatment and prevention agents

 

Sai Hanuman Sagar Boddu, Ph.D.
Assistant Professor of Pharmaceutics
S.Boddu@UTNet.utoledo.edu



Chemical Biology

Isaac T. Schiefer, PhD
Research Assistant Professor
Isaac.schiefer@utoledo.edu

Key Words:
Chemical Biology
Organic Synthesis
Alzheimer's Disease
Ischemic Brain Injury and Stroke

 

Cilia Biology

Surya Nauli, PhD
Assistant Professor
surya.Nauli@UToledo.Edu

Funding:      
American Heart Association (Nat’l; Scientist Developmental Grant)
National Institutes of Health (NHLBI; R21)
National Institutes of Health (NIDDK; R01)

Key Words: 
Cilia biology
Cardiovascular disease
Clinical Outcomes in Infectious Diseases
Cytosolic Sulfatransferase
Polycystic kidney disease

Diabetes

Marcia F. McInerney, PhD
Professor and Chair
Member Center for Diabetes and Endocrine Research
Adjunct Professor  Biochemistry and Cancer Biology
Adjunct Professor Pathology
Adjunct Professor Internal Medicine, Diabetes Metabolism and Endocrinology, U of Michigan
marcia.mcinerney@utoledo.edu

Funding:      
United States Department of Agriculture/ CSREES

Key words:
Diabetes (both type 1 and type 2)
Autoimmunity
Innate immunity
Toll-like receptors
Inflammation
Cytokines
Nutrition
Infection and Diabetes
Macrophages, T Cells, B cells

Drug Clearance, Targeting, Design, Delivery

Sai Hanuman Sagar Boddu, Ph.D.
Assistant Professor of Pharmaceutics
S.Boddu@UTNet.utoledo.edu  

Mariann Churchwell
Assistant Professor
mariann.churchwell@utoledo.edu

Funding:      
Am. College of Clinical Pharmacy Investigator Development grant

Key Words: 
Drug Clearance
Kidney Disease
Renal Replacement Therapy
Epidemiology of infectious diseases

Jerry Nesamony, PhD
Assistant Professor of Pharmaceutics
jerry.nesamony@utoledo.edu

Key Words: 
Biopolymeric nanoparticles
Drug delivery 
Dynamic light scattering
Liposomes
Microemulsions
Nanostructured liquid systems,
Rheology
Sub-ambient thermal analysis

Drug Metabolism, including prodrug and soft drug design 

 

Sai Hanuman Sagar Boddu, Ph.D.
Assistant Professor of Pharmaceutics
S.Boddu@UTNet.utoledo.edu

HIV/AIDS

Eric Sahloff
Assistant Professor
eric.sahloff@UToledo.Edu 

Key Words: 
Adherence/Patient care issues
HIV/AIDS
Pharmacokinetics/pharmacodynamics



Ischemic Brain Injury and Stroke

Isaac T. Schiefer, PhD
Research Assistant Professor
Isaac.schiefer@utoledo.edu

Key Words:
Chemical Biology
Organic Synthesis
Alzheimer's Disease
Ischemic Brain Injury and Stroke

Kidney Disease

Mariann Churchwell
Assistant Professor
mariann.churchwell@utoledo.edu

Funding:      
Am. College of Clinical Pharmacy Investigator Development grant

Key Words: 
Drug Clearance
Kidney Disease
Renal Replacement Therapy
Epidemiology of infectious diseases 

Surya Nauli, PhD
Assistant Professor
surya.Nauli@UToledo.Edu

Funding:      
American Heart Association (Nat’l; Scientist Developmental Grant)
National Institutes of Health (NHLBI; R21)
National Institutes of Health (NIDDK; R01)

Key Words: 
Cilia biology
Cardiovascular disease
Clinical Outcomes in Infectious Diseases
Cytosolic Sulfatransferase
Polycystic kidney disease

Jerry Nesamony, PhD
Assistant Professor of Pharmaceutics
jerry.nesamony@utoledo.edu

Key Words: 
Biopolymeric nanoparticles
Drug delivery
Dynamic light scattering
Liposomes
Microemulsions
Nanostructured liquid systems
Rheology
Sub-ambient thermal analysis 

Mass Spectrometry

Natural Products

Neurodegenerative Disorders

Youssef Sari, PhD
Assistant Professor
youssef.sari@utoledo.edu

Funding:
National Institutes of Health

Key words:
Oxidative stress
Synthetic neuroprotective peptide
Glutamate transport
Drug/Substance abuse

 

NMR

Hermann von Grafenstein, PhD
Associate Professor
hermann.grafenstein@utoledo.edu

Funding:      
National Institutes of Health (NIAID; R15)

Key words: 
Autoimmune diseases
Inflammation
Ligand-receptor interactions
Mass spectrometry
NMR
Peptide-MHC complexes
Protein structure determination
Toll-like receptor associated proteins



Organic Synthesis

Isaac T. Schiefer, PhD
Research Assistant Professor
Isaac.schiefer@utoledo.edu

Key words:
Chemical Biology
Organic Synthesis
Alzheimer's Disease
Ischemic Brain Injury and Stroke

Pharmacodynamics

Diane Cappelletty, PharmD
Associate Professor
diane.cappelletty@utoledo.edu

Key Words: 
Antimicrobial stewardship
Bacterial resistance
Clinical outcomes in infectious diseases
Fungal infections
Pharmacodynamics

Eric Sahloff
Assistant Professor
eric.sahloff@UToledo.Edu 

Key Words: 
Adherence/Patient care issues
HIV/AIDS
Pharmacokinetics/pharmacodynamics

Pharmacoeconomics

Varun Vaidya, PhD
Assistant Professor
varun.vaidya@utoledo.edu

Key words: 
Economic outcomes
Health Literacy
Health Outcomes
Health Services Research
Patient Compliance
Pharmacoeconomics 
Pharmaceutical care
Policy formulation

Pharmacokinetics

Eric Sahloff
Assistant Professor
eric.sahloff@UToledo.Edu 

Key Words: 
Adherence/Patient care issues
HIV/AIDS
Pharmacokinetics/pharmacodynamics

Rheology

Jerry Nesamony, PhD
Assistant Professor of Pharmaceutics
jerry.nesamony@utoledo.edu 

Key Words: 
Biopolymeric nanoparticles
Drug delivery
Dynamic light scattering
Liposomes
Microemulsions
Nanostructured liquid systems
Rheology
Sub-ambient thermal analysis

Zebra Fish

Ming-Cheh Liu, PhD
Associate Professor of Pharmacology
ming.liu@utoledo.edu

Funding:      
NIH R15; NSF

Key Words: 
Cytosolic sulfotransferase
Developmental pharmacology
Drug metabolism
Protein modification
Sulfation
Tyrosine sulfation
Tyrosylprotein sulfotransferase
Zebrafish