Department of Pharmacy Practice

Sai HanumanSagar Boddu, Ph.D.

Boddu photo

Assistant Professor of Pharmaceutics
Department of Pharmacy Practice

419.383.1959
Frederic and Mary Wolfe Center 114G
sboddu@utnet.utoledo.edu

Education

  • PhD in Pharmaceutics and Drug Design, University of Missouri
  • Masters in Pharmaceutics, NDMVP SAMAJ’S College Of Pharmacy, Nashik, Maharashtra, India
  • Bachelors in Pharmaceutics, Bapatla College of Pharmacy, Bapatla, Andhra Pradesh, India

Scope of Practice and Curriculum

Pharmaceutics and Drug Design

Professional Experience

  • Assistant Professor, The University of Toledo 2011 - present
  • Research Assistant, University of Missouri 2006 – 2010
  • Part-time Lecturer, University of Pune, Yeola Maharashtra, India 2005 – 2006
  • Research Associate, University of Pune, Yeola Maharashtra, India 2005 – 2006
  • Graduate Assistant, NDMVP Samaj's College of Pharmacy Nashik Maharashtra, India 2003 - 2005

Recent Publications

Book Chapters

  1. Boddu SHS, Gaudana R. Routes of drug delivery, In: Drug Delivery, Edited by Mitra AK, and published by Jones & Bartlett Learning, p. 335-356.
  2. Nguyen S, Baki G, Nesamony J, Boddu SHS. Vaginal drug delivery, In: Drug Delivery, Edited by Mitra AK, and published by Jones & Bartlett Learning, p. 50-69.
  3. Rittenhouse K, Atluri H, Boddu SHS, Mitra AK, Microdialysis - Utility in Establishing PK/PD Relationships in Ophthalmology, In: Treatise on Ocular Drug Delivery, 2013. Bentham Science, p. 161-202.
  4. Karla PK, Boddu SHS, Patel A, Mitra AK, Novel Strategies To Enhance Ocular Bioavailability, In: Treatise on Ocular Drug Delivery, 2013. Bentham Science, p. 140-160.
  5. Boddu SHS, Menees AL, Ray A, Mitra AK, A Brief Overview of Ocular Anatomy and Physiology, In: Treatise on Ocular Drug Delivery, 2013. Bentham Science, p. 3-19.
  6. Gunda S, Boddu SHS, Gupta J, Mitra AK, Ocular Pharmacokinetics: Challenges and Models, In: Duane's Foundations of Clinical Ophthalmology, 2012, J. B. Lippincott Co. p. 17337-17350
  7. Boddu SHS, Kwatra D, Mitra AK, Prodrug Strategies to Enhance Oral Drug Absorption, in Oral Bioavailability. 2011, John Wiley & Sons, Inc. p. 355-369.
  8. Kwatra D, Boddu SHS, Mitra AK, MDCK Cells and Other Cell Culture Models of Oral Drug Absorption, in Oral Bioavailability. 2011, John Wiley & Sons, Inc. p. 443-460.
  9. Karla PK, Boddu SHS, Dasari C, Mitra AK, Outward-Directed Transport, in Adler's Physiology of the Eye, 2011. Elsevier, p. 385-393.

Peer-Reviewed Articles

  1. Ako-Adounvo AM, Nagarwal RC, Oliveira L, Boddu SHS, Wang X, Dey S, Karla PK. Recent Patents on Ophthalmic Nanoformulations and Therapeutic Implications. Recent Pat Drug Deliv Formul. 2014 Sep 26.
  2. Patel MN, Lakkadwala S, Majrad MS, Injeti ER, Gollmer SM, Shah ZA, Boddu SHS, Nesamony J. Characterization and Evaluation of 5-Fluorouracil-Loaded Solid Lipid Nanoparticles Prepared via a Temperature-Modulated Solidification Technique. AAPS PharmSciTech. 2014 Jul 18.
  3. Howard MS, Boddu SHS, Mauro VF, Churchwell MD, Intravenous Compatibility of Conivaptan Hydrochloride with Select Cardiovascular Medications, AJHP, 2014 (In print)
  4. Boddu SHS, Gupta H, Bonam SP. Preclinical evaluation of a ricinoleic acid poloxamer gel system for transdermal eyelid delivery. Int J Pharm. 2014, 15;470(1-2):158-161
  5. Boddu SHS, Bonam SP, Wei Y, Alexander K. Preparation and in vitro evaluation of a pluronic lecithin organogel containing ricinoleic acid for transdermal delivery. International Journal of Pharmaceutical Compounding, 2014, 18(3):256-261
  6. Boddu SHS, Recovery of Lipophilic Drugs, Probes, AAPS Microdialysis FG Magazine.
  7. Boddu SHS, Bonam SP,  Rose Jung Development and Characterization of a Ricinoleic acid Poloxamer Gel System for Transdermal Eyelid Delivery. Drug Delivery and Industrial Pharmacy,  2014, 1-8.
  8. Boddu SHS, Gupta H, Patel S, Drug delivery to the back of the eye following topical administration, Recent Patents On Drug Delivery & Formulation, 2014 Jan 29.
  9. Nesamony J, Kalra A, Majrad MS, Boddu SHS, Jung R, Williams FE, Schnapp AM, Nauli SM, Kalinoski AL. Development and Characterization of Nanostructured Mists with Potential for Actively Targeting Poorly Water-Soluble Compounds into the Lungs. Pharm Res. 2013; 30(10):2625-39.
  10. Martha C, Boddu SHS, Churchwell M. Physical compatibility of sodium citrate catheter locking solution with ethanol and cefepime. Am J Health Syst Pharm. 2013; 70(11):932-7.
  11. Boddu SHS, Nesamony J. Utility of Transporter/Receptor(s) in Drug Delivery to the Eye.  World J Pharmacology. 2013; 2(1): 1-17
  12. Renukuntla J, Vadlapudi AD, Patel A, Boddu SHS, Mitra AK. Approaches for enhancing oral bioavailability of peptides and proteins. Int J Pharm. 2013;447, 75– 93. 
  13. Boddu SHS, Microdialysis: A Reliable and Cost Effective Technique to Study the Pharmacokinetics of Ocular Drugs, Probes, AAPS Microdialysis FG Magazine.
  14. Boddu SHS. Polymeric Nanoparticles for Ophthalmic Drug Delivery: An Update on Research and Patenting Activity. Recent Patent on Nanomedicine. 2012;2(2):96-112.
  15. Gaudana RJ, Gokulgandhi MR, Boddu SHS, Mitra AK. Recent overview of ocular patents. Recent Pat Drug Deliv Formul. 2012;6(2):95-106.
  16. Boddu SHS, Vaishya R, Jwala J, Vadlapudi A, Pal D, Mitra AK. Preparation and Characterization of Folate Conjugated Nanoparticles of Doxorubicin using PLGA-PEG-FOL Polymer. Med chem. 2012;2:68-75.
  17. Jwala J, Vadlapatla R, Vadlapudi A, Boddu SHS, Pal DJ, Mitra AK. Differential expression of folate receptor-alpha (FR-α), sodium dependent multivitamin transporter (SMVT) and amino acid transporter (B (0, +)) in human retinoblastoma (Y-79) and retinal pigment epithelial (ARPE-19) cell lines. J Ocul Pharmacol Ther. 2012;28(3):237-44. 
  18. Jwala J, Boddu SHS, Paturi DK, Shah S, Smith SB, Pal D, et al. Functional characterization of folate transport proteins in staten's seruminstitut rabbit corneal epithelial cell line. Curr Eye Res. 2011;36(5):404-16.
  19. Jwala J, Boddu SHS, Shah S, Sirimulla S, Pal D, Mitra AK. Ocular sustained release nanoparticles containing stereoisomeric dipeptide prodrugs of acyclovir. Journal of Ocular Pharmacology and Therapeutics. 2011;27(2):163-72.
  20. Boddu SHS, Jwala J, Chowdhury MR, Mitra AK. In vitro evaluation of a targeted and sustained release system for retinoblastoma cells using doxorubicin as a model drug. Journal of Ocular Pharmacology and Therapeutics. 2010;26(5):459-68.
  21. Earla R, Boddu SHS, Cholkar K, Hariharan S, Jwala J, Mitra AK. Development and validation of a fast and sensitive bioanalytical method for the quantitative determination of glucocorticoids-quantitative measurement of dexamethasone in rabbit ocular matrices by liquid chromatography tandem mass spectrometry. J Pharm Biomed Anal. 2010;52(4):525-33.
  22. Challa BR, Boddu SHS, Awen BZ, Chandu BR, Bannoth CK, Khagga M, et al. Development and validation of a sensitive bioanalytical method for the quantitative estimation of pantoprazole in human plasma samples by LC-MS/MS: Application to bioequivalence study. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 2010;878(19):1499-505.
  23. Janoria KG, Boddu SHS, Natesan S, Mitra AK. Vitreal pharmacokinetics of peptide-transporter-targeted prodrugs of ganciclovir in conscious animals. Journal of Ocular Pharmacology and Therapeutics. 2010;26(3):265-71.
  24. Boddu SHS, Gunda S, Earla R, Mitra AK. Ocular microdialysis: A continuous sampling technique to study pharmacokinetics and pharmacodynamics in the eye. Bioanalysis. 2010;2(3):487-507.
  25. Boddu SHS, Jwala J, Vaishya R, Earla R, Karla PK, Pal D, et al. Novel nanoparticulate gel formulations of steroids for the treatment of macular edema. Journal of Ocular Pharmacology and Therapeutics. 2010;26(1):37-48.
  26. Gaudana R, Jwala J, Boddu SHS, Mitra AK. Recent perspectives in ocular drug delivery. Pharm Res. 2009;26(5):1197-216.
  27. Janoria KG, Boddu SHS, Wang Z, Paturi DK, Samanta S, Pal D, et al. Vitreal pharmacokinetics of biotinylated ganciclovir: Role of sodium-dependent multivitamin transporter expressed on retina. Journal of Ocular Pharmacology and Therapeutics. 2009;25(1):39-49.
  28. Karla PK, Earla R, Boddu SHS, Johnston TP, Pal D, Mitra A. Molecular expression and functional evidence of a drug efflux pump (BCRP) in human corneal epithelial cells. Curr Eye Res. 2009;34(1):1-9.
  29. Agarwal S, Boddu SHS, Jain R, Samanta S, Pal D, Mitra AK. Peptide prodrugs: Improved oral absorption of lopinavir, a HIV protease inhibitor. Int J Pharm. 2008;359(1-2):7-14.
  30. Janoria KG, Gunda S, Boddu SHS, Mitra AK. Novel approaches to retinal drug delivery. Expert Opinion on Drug Delivery. 2007;4(4):371-88.
  31. Derle DV, Gujar KN, Boddu SHS. Adverse effects associated with the use of nonsteroidal antiinflammatory drugs: An overview. Indian Journal of Pharmaceutical Sciences. 2006;68(4):409-14.
  32. Derle DV, Boddu SHS, Pimpale R. Microemulsion as a vehicle for transdermal permeation of nimesulide. Indian Journal of Pharmaceutical Sciences. 2006;68(5):622-5.
  33. Derle DV, Boddu SHS, Kotwal RS, Ingole RD, Chavan SS. A compartive in vitro evaluation of transdermal permeation of  valdecoxib and its complex with HP-beta-cyclodextrin from microemulsion based gel. Indian Drugs  2006;48(8):625-629.
  34. Deelip Derle, Boddu SHS, Manoj Magar. Studies on the Preparation, Characterization and Solubility of β-Cyclodextrin -Satranidazole Inclusion Complexes. Indian Journal of Pharmaceutical Education and Research. 2006;40(6):232-236.
  35. Derle DV, Khangoankar S, Boddu SHS, Pimpale R 2005. Development of dissolution medium for Pioglitazone, Indian Drugs. 2005;42(5):313-315.
  36. Sagar GV, Sastry BS, Boddu SHS, 2003. Determination of Lacidipine in Pharmaceutical formulations by Oxidimetry, Journal- institution of Chemists India 75(4):133-134.

Recent Awards

  • UMKC-Vice Chancellor for Student Affairs and Enrollment Management Honor Recipient, Fall-2010
  • UMKC-Chancellor's Doctoral Fellowship, (2008-10)
  • UMKC-Chancellor Non-Resident award, (2006-10)
  • Best poster award for Research Day 2010 at UMKC
Last Updated: 3/22/15