What is Bioinformatics ?

Bioinformatics is the use of computers to extract meaning from DNA sequences. Genome sequencing is becoming much cheaper and faster, but from a billion As, Gs, Cs and Ts, how do we link genetic variations with medically relevant traits, and how do we predict gene function or regulation? Knowledge in these areas is essential for biomedical researchers, whether in academia, government, or the private sector. These tools are being introduced into the practice of medicine, and into general biology in areas such as ecology, bioremediation, and agriculture. This knowledge is also valuable for careers in business, law, and computer science.

The increasing application of genomics in biotech and pharmaceutical research and development has created a huge commercial market for bioinformatics worldwide. As per our latest research report's estimation, the global bioinformatics market, which reached the mark of around US$ 3 Billion in 2010, will expand at a CAGR of around 25% during 2012-2015 as the declining cost of human genome sequencing and increasing public and private sector investment will give a significant boost to the industry.
http://www.bizjournals.com/prnewswire/ press_releases/2012/03/15/SP70895



Program in Bioinformatics and Proteomics/Genomics

The Program in Bioinformatics and Proteomics/ Genomics (BIPG) at The University of Toledo provides students with the advanced analytical tools and approaches needed for life at the interface between computer science and molecular biology � great preparation for careers in genomic medicine, intellectual property law, biotechnology, and more.


Contact Information
The Program Office is located in the CCE Building on The University of Toledo Health Science Campus. Please contact us for more information about our program.

Master of Science
(For those who already have a BS or BA; combines bioinformatics courses with a research project)


Ms. Jo Anne Gray, Secretary
Bioinformatics Program
Phone: 419.383.6883


Dr. Robert M. Blumenthal,
Bioinformatics Program


Professional Science Masters
(Combines bioinformatics, biomarkers and business courses with an internship)
Dr. Keith Crist, Associate Director
Jacobson Center for Clinical & Translational Research


Dual-degree "pipeline" program 
(BS in Biology and MS in Bioinformatics in 51/2 y)

Dr. John Gray, Associate Professor
Department of Biological Sciences


Core Courses In Bioinformatics

1. Fundamentals of Bioinformatics (BIPG 5100/7100) Introduction to the full scope of bioinformatics, along with proteomic and genomic approaches.

2. Statistical Methods in Bioinformatics (BIPG 5200/7200) Training in statistical methods used in BPG (such as hidden Markov models).

3. Introduction to Bioinformatic Computation (BIPG 6100/8100) Handling and manipulation of databases, and introduction to computer programming skills needed to manipulate large quantities of nucleic acid and protein sequence data.

4.EITHER:  Applications of BPG (BIPG6400/8400) Faculty members using these methods discuss and demonstrate how these approaches are used to solve real-world research problems.

OR:  Biomarker Discovery, Validation and Implementation (BRIM6200/8200)  Overview of the biomarker discovery process and validation techniques, followed by development of individual (patient-specific) genomic or immunological medical interventions.


The program also includes a variety of other bioinformatics or elective courses, selected by you in partnership with your advisory committee to fit your goals. Electives may include courses in molecular biology, computer science, business, and statistics.


Degree Programs

Master of Science

The MS degree in Biomedical Sciences, with a concentration in Bioinformatics, is for those who want a research and development (R&D) career in in the computational or biological sciences. A key part of the training is a research project, so you have real experience in the application and design of bioinformatic tools. The program usually takes just two years to complete.


Professional Science Masters

The PSM in Biomarkers & Diagnostics is for those who want a career in industry. PSM programs in general are described here: http://www.sciencemasters.com/An internship with a commercial partner is scheduled for the summer term. The program usually takes one year to complete.

Dual-degree pipeline program

UT has established a 51/2-year dual-degree program, so that students can earn both a bachelors degree in biological sciences and a masters degree in bioinformatics. Students are formally admitted to

the pipeline after their 2nd year as biological sciences majors at UT.


Scholarship Opportunities

Some tuition scholarships are available. Currently these are of two types. One is from the UT College of Graduate Studies, for students entering with (and maintaining) strong GPAs. The second is for pipeline students in the masters component of their studies; this is through the Choose Ohio First program, and awardees must be Ohio residents.

 Application Requirements

>    Except for pipeline applicants, you should have earned a bachelor�s degree or graduate degree from an accredited college or university by the time you enter the program.

>      GPA of 3.0 or above. [GPA of2.5 or above may apply for provisional one-term acceptance, which would change to regular status if first term yields a GPA of 3.0 or above.]

>      Minimum GRE combined verbal + quantitative of 300 (1050 on old scale) and 3.5 (analytical). The GRE is not required if you have recent MCAT scores as an alternative.

>      Official transcripts for undergraduate and any graduate education.

>      Three letters of recommendation from college faculty or research supervisors.

>      Previous research or relevant job experience is considered, but not required.

>      Completed application form (online) and accompanying application fee (or waiver).

>      TOEFL (if applicable): 550 or higher (paper version), 213 or higher (computer), and 80 or higher (internet). IELTS scores (6.5 or higher) are accepted in place of TOEFL.  However, as of Spring 2014 admissions, IELTS will no longer be accepted.

Students can begin in either fall or spring, but fall entry is recommended. Admissions are made on a rolling basis until the class is filled; there is no fixed deadline.


For complete details, visit the BPG Program website: http://www.utoledo.edu/med/depts/bioinfo/


Online applications:  http://apply.utoledo.edu/