Surya Nauli, Ph.D.
Vice Chair, Department of Pharmacology
Minnesota State University, Biotechnology & Chemistry
Loma Linda University, Pharmacology
|NIH Fellow||Harvard Medical School, Cilia Biology|
- Cilia Biology
- Cardiovascular Disease
- Polycystic Kidney Disease
Nauli SM, Kawanabe Y, Kaminski JJ, Pearce WJ, Ingber DE, Zhou J. Endothelial cilia are fluid-shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1. Circulation. 2008 Mar 4;117(9):1161-71.
AbouAlaiwi WA, Takahashi M, Mell BR, Jones TJ, Ratnam S, Kolb RJ, Nauli SM. Ciliary polycystin-2 is a mechanosensitive calcium channel involved in nitric oxide signaling cascades. Circ Res. 2009 Apr 10;104(7):860-9.
AbouAlaiwi WA, Ratnam S, Booth RL, Shah JV, Nauli SM. Endothelial cells from humans and mice with polycystic kidney disease are characterized by polyploidy and chromosome segregation defects through survivin down-regulation. Hum Mol Genet. 2011 Jan 15;20(2):354-67.
Jin X, Mohieldin AM, Muntean BS, Green JA, Shah JV, Mykytyn K, Nauli SM. Cilioplasm is a cellular compartment for calcium signaling in response to mechanical and chemical stimuli. Cell Mol Life Sci. 2013 [In Press]
AbouAlaiwi WA, Muntean BS, Ratnam S, Joe B, Liu L, Booth RL, Rodriguez I, Herbert BS, Bacallao RL, Fruttiger M, Mak TW, Zhou J, Nauli SM. Survivin-induced abnormal ploidy contributes to cystic kidney and aneurysm formation. Circulation. 2014 Feb 11;129(6):660-72.