Research and Sponsored Programs

Animal Care and Use in Research

Why Animal Research Is Important To Humans And Animals

Researchers who conduct animal research must adhere to strict federal policies and regulations that help ensure that the animals will be in responsible, humane and conscientious hands. For truthful and accurate results, the animals must be healthy and well cared for. For this reason, scientists who work with animals are devoted to making sure their animal partners treated with care and concern. Humane and gentle treatment is the utmost concern in animal care at The University of Toledo. 

Humans are not the only beings that benefit from this necessary and critical research. Many animals live long and healthy lives thanks to the medical knowledge obtained through animal research.

In accordance with The Guide and Use of Laboratory Animals, Animal Welfare Regulations; The Public Health Service Policy on Humane Care and Use of Laboratory Animals; and other applicable federal (Appendixes C and D) state, and local laws, regulations, and policies – All research activities involving animals at The University of Toledo must be done under the oversight of the Institutional Animal Care and Use Committee (IACUC).

Research Activities - Mitigating Impacts Due to COVID-19
IRB Manager for IACUC   IRB Manager Training for IACUC

IACUC staff
Elaine Joseph, PhD - Office of Research & Sponsored Programs

Elaine Joseph, PhD

Project Administrator, IACUC, IBC, IRE
The University of Toledo
Office of Research & Sponsored Programs
Main Campus | R1 1020E

Phone: 419.383.4251 | Email:

Anne Izzi, JD - Director, Sponsored Programs  Anne Izzi, JD

Director of Sponsored Programs
The University of Toledo
Office of Research and Sponsored Programs
Main Campus | R1 1020A

Phone: 419.530.6226 | Email:
Protocol Information
Frequently Asked Questions About Animal Research Protocols | Update 11/18/2019
IACUC Animal Use Protocol xForm Sample | Update 11/18/2020
IACUC Guidelines
Administration of Substances Guideline | New 6/24/2021
Animal Research Being Done at Another PHS Assured Site | Update 8/7/2019
Animal Re-Use | Updated 6/24/2021 
Animal Transportation | Updated 6/24/2021
Blood Collection | Updated 4/23/2021
Breeding and Breeding Cage Densities | Updated 11/20/2020
Buprenorphine Dilution and Labeling Instructions | Updated 10/9/2020
Custom Antibodies | Updated 2/1/2019 
Drug Dilution and Storage Guidelines | Updated 1/20/2020
Euthanasia Guideline | Update 9/18/2020
Euthanasia of Neonatal Rodents | Updated 7/17/2019
Food and Fluid Restriction | Updated 3/11/2021
Housing Space Requirements for Laboratory Animals | Updated 9/12/2019
Multiple Survival Surgeries | Updated 3/18/2021
Photography and Videography in UToledo DLAR Animal Use Areas | Updated 1/23/2020
Prolonged Restraint | Updated 3/11/2021
Reporting Animal Welfare Concerns | Updated 7/1/2021
Rodent Analgesia | Updated 12/08/2020
Rodent Anesthesia | Updated 10/21/2020
Rodent Genotyping | Updated 7/17/2019
Rodent Tumor Monitoring | Updated 4/6/2020
Satellite Animal Facilities Operating Procedures | Updated 7/17/2019
Social Housing and Enrichment | Updated 6/24/2021
Surgery | Updated 10/24/2019
Training and Training Personnel Involved with Animal Activities | Updated 01/18/2020
Use of Adjuvants and Polyclonal Antibody Production | Updated 3/18/2021
Use of DMR to Approve Protocols Subsequent to FCR - Signed | Updated 8/6/2019
Use of Non-Pharmaceutical Grade Chemicals in Research Animals | Updated 8/6/2019
Veterinary Verification and Consultation (VVC) | Updated 11/20/2020

IACUC Standard Operating Procedures
Closure of IACUC Protocols by PI Request or Expiration | Updated 11/20/2020
Handling Allegations of Non-Compliance | Updated 7/21/2021
Holding of Animals Not Covered by Active Animal Care and Use Protocols | Updated 12/13/2018
Guillotine and Scissor Maintenance and Testing | Updated 7/17/2019
Membership, Roles and Responsibilities | Updated 8/22/2019
Protocol Pre-Review | Updated 11/20/2020
Protocol and Amendment Review | Updated 9/16/2020
Vaporizer Maintenance | Updated 10/24/2019

Other Animal-Related Research Information
DLAR Animal Requisition Form
UToledo Policy on Laboratory Animal Welfare, Care and Use | Updated 4/5/2019
Facility and Vet Care Information for NIH Grants | Updated 11/8/2018 
AVMA Guidelines for the Euthanasia of Animals: 2020 Edition
NIH OLAW - Preparing the Invertebrate Animal Section for Submission to the NIH | Updated 8/3/2020
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Last Updated: 8/3/21