BIOE 1000: Orientation and Introduction to Bioengineering

Designation:    Required
Description:    Orientation to the University of Toledo, the College of Engineering and the Department of Bioengineering. Topics also include a general introduction to the field of bioengineering, and a survey of engineering computing resources.
Prerequisite:    Acceptance into Bioengineering
Textbook:    Course Units for BIOE 1000: Introduction to Bioengineering
D.A. Christensen, R.D. Rabbitt, and A.M. Yamauchi (2004)
This coursepack contains all of the course units discussed in the lectures as well as information on the major project.
Objectives:    To learn that Bioengineering is a very quantitative field 
To learn that engineering principles can be applied to living systems 
To obtain a realistic view of the Bioengineering curriculum and of the Bioengineering field 
To demonstrate key principles and engineering concepts taught in various courses throughout the Bioengineering curriculum 
To help students make an informed decision about whether or not Bioengineering is in line with their skills and interests
Topics:    This course provides a one-semester overview of the biomechanical and bioelectrical aspects of the Bioengineering field. The course is broken down into unit modules that illustrate key engineering principles and concepts. A major project based on the modeling of the cardiovascular system (implemented in MATLAB and PSpice) integrates the course units.

Basic units, dimensions, scientific notation 
Record keeping - the role of a laboratory notebook 
Darcy's law - pressure driven flow through a membrane 
Poiselle's law - pressure driven flow through a tube or pipe 
Hooke's Law - elasticity and stress/strain relationship 
Starling's Law of the heart, windkessel elements, and conservation of mass/volume 
Euler's method - first order time constants and numerical solution of differential equations in MATLAB 
Equilibrium statics and dynamics - muscles, leverage, work, energy, power, force, levers, and moments 
Ohm's law - current, voltage, and resistance 
Kirchhoff's voltage and current laws 
Operational amplifiers 
Coulomb's law, capacitors, fluid/electrical analog 
Series and parallel combinations of resistors and capacitors (RCs) 
Thevenin equivalent circuits and first order RC time constants 
Nernst potential, cell membrane equivalent circuit 
Fourier transforms - AC current and frequency domain
Schedule:    3 - 50 minute lectures per week
1 - 50 minute project review session per week
Contribution:    Engineering topics
(a)    An ability to apply knowledge of mathematics, science, and engineering
(b)    An ability to design and conduct experiments, as well as to analyze and interpret data
(c)    An ability to design a system, component, or process to meet desired needs within realistic constraints such as economic, environmental, social, political, ethical, health and safety, manufacturability, and sustainability
(e)    An ability to identify, formulate, and solve engineering problems
(g)    An ability to communicate effectively
(i)    A recognition of the need for, and an ability to engage in life-long learning
(j)    A knowledge of contemporary issues
(k)    An ability to use the techniques, skills, and modern engineering tools necessary for engineering practice
(8a)    An understanding of biology and physiology
(8c)    The ability to make measurements on and interpret data from living systems, addressing the problems associated with the interaction between living and non-living materials and systems
Prepared by:    Scott Molitor ( and Tammy Phares (

Last Updated: 6/27/22