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BIOE 2200: Biomaterials

Designation:    Required
  
Description:    Physical and chemical properties of materials commonly used in medicine. Inflammatory, immunogenic, carcinogenic and toxicologic responses within host tissues. Testing and evaluation strategies for effective use of materials in medicine and biology.
  
Prerequisite:    PHYS 2130; MATH 1860 or 1930; CHEM 1240.
  
Textbook:    There is no suggested textbook for Biomaterials. Lecture notes are available on the web in Adobe Acrobat and PowerPoint formats
  
Objectives:    To apply knowledge of material science to biological systems 
The ability to select and design biomaterials for applications as devices in medical and clinical fields 
To understand and solve problems arising from material and host tissue interaction following implantation. 
To understand regulations on the use of implantable biomaterials (outcome n) 
To develop communication skills with papers and presentations
  
Topics:    Biomaterials Science and Engineering Overview 
Structure of Solids 
Characterization of Materials 
Metals 
Ceramics/Polymers 
Polymers/Hydrogels 
Natural Materials 
Structure Property Relationships 
Tissue Response to Implants 
In-vivo and in-vitro testing of biomaterials 
Regulatory Environment 
Artificial Organs 
Cardiovascular Applications 
Orthopaedic Applications
  
Schedule:    2 - 1 hour 15 minute lectures per week
  
Contribution:    Engineering topics
  
Outcomes:   
(a)    An ability to apply knowledge of mathematics, science, and engineering
(c)    An ability to design a system, component, or process to meet desired needs within realistic constraints such as economic, environmental, social, political, ethical, health and safety, manufacturability, and sustainability
(e)    An ability to identify, formulate, and solve engineering problems
(8a)    The capability to apply advanced mathematics (including differential equations and statistics), science, and engineering to solve the problems at the interface of engineering and biology
  
Prepared by:    Scott Molitor (scott.molitor@utoledo.edu) and Tammy Phares (tamara.phares@utoledo.edu).
Last Updated: 2/7/17