Bioengineering

BIOE 4710 Biomechanics of Soft and Hard Tissues

Designation:		Elective
Description:		Composite and hierarchial models of bones; models of bone remodeling. Soft tissue models; linear and nonlinear viscoelasticity, Fung's quasilinear viscoelastic theory. Biphasic and triphasic models and mechano-ionic interactions.
Prerequisite:		BIOE 3110
Textbook:		None
Objectives:		To understand the molecular level characteristics of extracellular matrices that form musculoskeletal tissues such as tendons, ligaments, cartilage, muscle and bone.  To understand the structural hierarchial organization and physiology of musculoskeletal tissues.  To understand the biological and physiological factors that render these tissues the unique mechanical properties they have.  To understand the concepts such as stress, strain, stress-strain relationships, viscoelasticity and how these concepts apply to musculoskeletal tissues.  To understand how the mechanical function of these tissues alter with age, disease and trauma.
Topics:		Stress-Strain  Anisotropy/Composite Mechanics  Linear Viscoelasticity  Proteins of the Extracellular Matrix  Physiology and Mechanics of Tendons/Ligaments  Physiology and Mechanics of Bone  Physiology and Mechanics of Muscle  Physiology and Mechanics of Cartilage
Schedule:		2 - 1 hour and 15 minute lectures per week
Contribution:		Engineering topics
Outcomes:		(a)    An ability to apply knowledge of mathematics, science, and engineering (e)    An ability to identify, formulate, and solve engineering problems (8a)    An understanding of biology and physiology
Prepared by:		Scott Molitor (scott.molitor@utoledo.edu) and Tammy Phares (tamara.phares@utoledo.edu).