Xiaohuan Chen
Research Assistant
Affiliation: Kevin Pan, M.D., Ph.D.
College of Medicine and Life Sciences
Department of Medical Microbiology& Immunology
Lab: HEB 263
Phone: (419) 383-5421
Email: Xiaohuan.Chen@utoledo.edu
Education
Southern Medical University School of Basic Medicine
Guangzhou, China
Ph. D. Completed Jun 2018
Research: Identification of novel anti-inflammatory drugs and their functional mechanisms
Southern Medical University School of Basic Medicine
Guangzhou, China
B.S. Completed Jun 2011
Major: basic Medicine
PUBLICATIONS
- Dolin HH, Papadimos TJ, Stepkowski S, Chen X, Pan ZK. (2018). A Novel Combination of Biomarkers to Herald the Onset of Sepsis Prior to the Manifestation
of Symptoms. Shock. 2018 Apr; 49(4): 364-370.
- Jiang, Y., Smith, L., Pan, W. W., Chen, X., Wang, J., Lu, X. Y., ... Pan, Z. K. (2016).
Bacterial chemoattractant synergizes with LPS to induce inflammation via upregulating
TLR4. International Journal of Clinical and Experimental Medicine, 9(3), 6005-6013.
- Liqun Wang, Haihua Luo, Xiaohuan Chen, Yong Jiang, Qiaobing Huang (2014). Functional characterization of S100A8 and S100A9 in altering monolayer permeability
of human umbilical endothelial cells. PLoS One 9(3): e90472.
- YE Ping, CAI Jun-wei, FU Xiao-xia, CUI Hang, LIU Ya-wei, CHEN Xiao-huan, LUO Hai-hua,
LI Yu-sheng, LIU Yun, JIANG Yong, LIU Jing-hua. Effects of p38 MAPK on SETD4 expression and location in p38 +/+ and p38 -/- cells
treated with sodium arsenite. Chin J Pathophysiol, 2012, 28(5): 878-883.
- Wang Juan, Xiaohuan Chen, Jingyu Feng, Xueou Zheng, Peng Deng, Yong Jiang. Study of Signaling Mechanism of IP-10 Expression Induced by MRP14 in THP-1cells, Weixunhuanxue Zazhi, 2009, 19(4):106.
EXPERIMENT SKILLS
Proficient PCR skills including RT-PCR, Real Time PCR
Skilled in DNA and RNA extraction, agarose gel electrophoresis and SDS PAGE
Experience in bacteria and cell culture
Excelled at Western Blotting and protein- protein interaction (Protein pull down,
Co-immunoprecipitation)
Familiar with various protein purification methods
Animal experiment skills with mouse and rabbit
Skilled at using molecular biology application software such as DNAMAN, Primer, BLAST